Carlos Sepúlveda Guzmán Profesor Asistente

    Grado Académico

    Doctor en Nutrición y Alimentos, Universidad de Chile.

    Título(s) Profesional

    Profesor de Educación Física, Universidad de Playa Ancha.

    Descripción

    Carlos Sepúlveda Guzmán es Profesor de Educación Física de la Universidad de Playa Ancha y Doctor en Nutrición y Alimentos de la Universidad de Chile. Realizó su postdoctorado en el Instituto de Nutrición y Alimentos de la Universidad de Chile. Actualmente es Profesor Asistente en el Instituto de Ciencias de la Salud de la Universidad de O’Higgins.

    La línea de investigación del Dr. Sepúlveda está enfocada en dos aspectos: a) Estudiar el papel que juega el ejercicio físico sobre la prevención y tratamiento de enfermedades relacionadas a la obesidad con énfasis en músculo esquelético e hígado; b) Desarrollar herramientas de bajo costo y fácil aplicación para la valoración del rendimiento humano en contextos clínicos.

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    • REVISTA BMC Geriatrics
    • 2026

    Randomized, double-blind, placebo-controlled trial of fecal microbiota transplantation from young physically active donors to promote resilient aging: clinical trial protocol (ARMOR study)


    • Camila Astudillo-Guerrero • Angel Garrido • Dominique Masferrer • Carlos Andrés Sepúlveda Guzmán • Loreto Olavarría

    http://dx.doi.org/10.1186/s12877-025-06920-7

    • REVISTA Scientific Reports
    • 2026

    FKBP51 disrupts the insulin signaling pathway and impairs mitochondrial bioenergetics in HepG2 cells


    • Camila Donoso-Barraza • Melissa Díaz-Roblero • Carlos Andrés Sepúlveda Guzmán • Anais Villegas-Bravo • Sandra A. Soto-Alarcón

    http://dx.doi.org/10.1038/s41598-026-40414-9

    • REVISTA BMC Geriatrics
    • 2026

    Randomized, double-blind, placebo-controlled trial of fecal microbiota transplantation from young physically active donors to promote resilient aging: clinical trial protocol (ARMOR study)


    • Camila Astudillo-Guerrero • Angel Garrido • Dominique Masferrer • Carlos Andrés Sepúlveda Guzmán • Loreto Olavarría

    http://dx.doi.org/10.1186/s12877-025-06920-7

    • REVISTA Scientific Reports
    • 2026

    FKBP51 disrupts the insulin signaling pathway and impairs mitochondrial bioenergetics in HepG2 cells


    • Camila Donoso-Barraza • Melissa Díaz-Roblero • Carlos Andrés Sepúlveda Guzmán • Anais Villegas-Bravo • Sandra A. Soto-Alarcón

    http://dx.doi.org/10.1038/s41598-026-40414-9

    • REVISTA Scientific Reports
    • 2025

    Validity and reliability of the step test to estimate maximal oxygen consumption in pediatric population


    • Gerardo Weisstaub • Jose Gonzalez • José González Farías • Ignacio Orizola • Juan Borquez

    http://dx.doi.org/10.1038/s41598-024-84336-w

    • REVISTA Scientific Reports
    • 2025

    Validity and reliability of the step test to estimate maximal oxygen consumption in pediatric population


    • Gerardo Weisstaub • Jose Gonzalez • José González Farías • Ignacio Orizola • Juan Borquez

    http://dx.doi.org/10.1038/s41598-024-84336-w

    • REVISTA JAMA Network Open
    • 2025

    Long-Term Obesity and Biological Aging in Young Adults


    • Paulina Correa-Burrows • Raquel Burrows • Cecilia Albala • Carlos Andrés Sepúlveda Guzmán • Felipe Salech

    http://dx.doi.org/10.1001/jamanetworkopen.2025.20011

    • REVISTA PlosOne
    • 2025

    Children and adolescents with overweight or obesity exhibit poor cardiorespiratory performance and elevated energy expenditure during an exercise task


    • Carlos Andrés Sepúlveda Guzmán • Matías Monsalves-Álvarez • Rodrigo Troncoso • Gerardo Weisstaub

    http://dx.doi.org/10.1371/journal.pone.0327875

    • REVISTA Pediatric Research
    • 2025

    Perspective Review: Advancing toward the diagnosis of sarcopenia in the pediatric population


    • Marcelo Flores-Opazo • Matías Monsalves-Álvarez • Carlos Andrés Sepúlveda Guzmán • Sebastián Jannas-Vela • Paz Fernández Valero

    http://dx.doi.org/10.1038/s41390-025-04716-4

    • REVISTA JAMA Network Open
    • 2025

    Long-Term Obesity and Biological Aging in Young Adults


    • Paulina Correa-Burrows • Raquel Burrows • Cecilia Albala • Carlos Andrés Sepúlveda Guzmán • Felipe Salech

    http://dx.doi.org/10.1001/jamanetworkopen.2025.20011

    • REVISTA PlosOne
    • 2025

    Children and adolescents with overweight or obesity exhibit poor cardiorespiratory performance and elevated energy expenditure during an exercise task


    • Carlos Andrés Sepúlveda Guzmán • Matías Monsalves-Álvarez • Rodrigo Troncoso • Gerardo Weisstaub

    http://dx.doi.org/10.1371/journal.pone.0327875

    • REVISTA Pediatric Research
    • 2025

    Perspective Review: Advancing toward the diagnosis of sarcopenia in the pediatric population


    • Marcelo Flores-Opazo • Matías Monsalves-Álvarez • Carlos Andrés Sepúlveda Guzmán • Sebastián Jannas-Vela • Paz Fernández Valero

    http://dx.doi.org/10.1038/s41390-025-04716-4

    • REVISTA Molecular and Cellular Biochemistry
    • 2024

    Folate induces stemness and increases oxygen consumption under glucose deprivation by notch-1 pathway activation in colorectal cancer cell


    • Juan Rodríguez • Matías Monsalves-Álvarez • Carlos Andrés Sepúlveda Guzmán • Camila Donoso-Barraza • Rodrigo Troncoso

    http://dx.doi.org/10.1007/s11010-024-04987-1

    • REVISTA Journal of Functional Morphology and Kinesiology
    • 2024

    Cycling Isokinetic Peak Force Explains Maximal Aerobic Power and Physiological Thresholds but Not Cycling Economy in Trained Triathletes


    • Felipe Giancaspero • Carlos Burgos-Jara • Carlos Andrés Sepúlveda Guzmán • Danni Haichellis • Roberto Meneses-Valdés

    http://dx.doi.org/10.3390/jfmk9040273

    • REVISTA Molecular and Cellular Biochemistry
    • 2024

    Folate induces stemness and increases oxygen consumption under glucose deprivation by notch-1 pathway activation in colorectal cancer cell


    • Juan Rodríguez • Matías Monsalves-Álvarez • Carlos Andrés Sepúlveda Guzmán • Camila Donoso-Barraza • Rodrigo Troncoso

    http://dx.doi.org/10.1007/s11010-024-04987-1

    • REVISTA Journal of Functional Morphology and Kinesiology
    • 2024

    Cycling Isokinetic Peak Force Explains Maximal Aerobic Power and Physiological Thresholds but Not Cycling Economy in Trained Triathletes


    • Felipe Giancaspero • Carlos Burgos-Jara • Carlos Andrés Sepúlveda Guzmán • Danni Haichellis • Roberto Meneses-Valdés

    http://dx.doi.org/10.3390/jfmk9040273

    • REVISTA Biological Research
    • 2023

    The CB1 cannabinoid receptor regulates autophagy in the tibialis anterior skeletal muscle in mice


    • Carlos Andrés Sepúlveda Guzmán • Juan Manuel Rodriguez • Matías Monsalves Álvarez • Camila Donoso-Barraza • Francisco Pino-de la Fuente

    http://dx.doi.org/10.1186/s40659-023-00426-5

    • REVISTA Frontiers in Nutrition
    • 2023

    High-intensity interval training prevents muscle mass loss in overweight Chilean young adults during a hypocaloric-Mediterranean diet: a randomized trial


    • Matías Monsalves Álvarez • Teresa Jimenez • Daniel Bunout • Gladys Barrera • Sandra Hirsch

    http://dx.doi.org/10.3389/fnut.2023.1181436

    • REVISTA Biological Research
    • 2023

    The CB1 cannabinoid receptor regulates autophagy in the tibialis anterior skeletal muscle in mice


    • Carlos Andrés Sepúlveda Guzmán • Juan Manuel Rodriguez • Matías Monsalves Álvarez • Camila Donoso-Barraza • Francisco Pino-de la Fuente

    http://dx.doi.org/10.1186/s40659-023-00426-5

    • REVISTA Frontiers in Nutrition
    • 2023

    High-intensity interval training prevents muscle mass loss in overweight Chilean young adults during a hypocaloric-Mediterranean diet: a randomized trial


    • Matías Monsalves Álvarez • Teresa Jimenez • Daniel Bunout • Gladys Barrera • Sandra Hirsch

    http://dx.doi.org/10.3389/fnut.2023.1181436

    • REVISTA BMJ Open Sport & Exercise Medicine
    • 2023

    Next steps to advance general physical activity recommendations towards physical exercise prescription: a narrative review


    • Raúl Festa • Emilio Jofré Saldía • Alejandro Candia • Matías Monsalves Álvarez • Marcelo Alejandro Flores Opazo

    http://dx.doi.org/10.1136/bmjsem-2023-001749

    • REVISTA BMJ Open Sport & Exercise Medicine
    • 2023

    Next steps to advance general physical activity recommendations towards physical exercise prescription: a narrative review


    • Raúl Festa • Emilio Jofré Saldía • Alejandro Candia • Matías Monsalves Álvarez • Marcelo Alejandro Flores Opazo

    http://dx.doi.org/10.1136/bmjsem-2023-001749

    • REVISTA Food and Chemical Toxicology
    • 2022

    Hydrogen sulfide disrupts insulin-induced glucose uptake in L6 skeletal muscle cells


    • Camila Donoso-Barraza • Juan Borquez • Carlos Andrés Sepúlveda Guzmán • Francisco Díaz-Castro • Claudia Sepulveda-Quiñenao

    http://dx.doi.org/10.1016/j.fct.2022.113083

    • REVISTA Food and Chemical Toxicology
    • 2022

    Hydrogen sulfide disrupts insulin-induced glucose uptake in L6 skeletal muscle cells


    • Camila Donoso-Barraza • Juan Borquez • Carlos Andrés Sepúlveda Guzmán • Francisco Díaz-Castro • Claudia Sepulveda-Quiñenao

    http://dx.doi.org/10.1016/j.fct.2022.113083

    • REVISTA Sports Medicine Open
    • 2021

    Modified Talk Test: A randomised cross-over trial investigating the comparative utility of two "Talk Test" for determining aerobic training zones in overweight and obese patients


    • Ignacio Orizola-Cáceres • Hugo Cerda-Kohler • Carlos Burgos-Jara • Roberto Meneses-Valdés • Rafael Gutierrez-Pino

    http://dx.doi.org/10.21203/rs.3.rs-21678/v2

    • REVISTA Sports Medicine Open
    • 2021

    Modified Talk Test: A randomised cross-over trial investigating the comparative utility of two "Talk Test" for determining aerobic training zones in overweight and obese patients


    • Ignacio Orizola-Cáceres • Hugo Cerda-Kohler • Carlos Burgos-Jara • Roberto Meneses-Valdés • Rafael Gutierrez-Pino

    http://dx.doi.org/10.21203/rs.3.rs-21678/v2

    • REVISTA Nutrients
    • 2020

    ?-Hydroxybutyrate Increases Exercise Capacity Associated with Changes in Mitochondrial Function in Skeletal Muscle


    • Matías Monsalves Álvarez • Pablo Esteban Morales • Mauricio Castro-Sepulveda • Carlos Andrés Sepúlveda Guzmán • Juan Manuel Rodriguez

    http://dx.doi.org/10.3390/nu12071930

    • REVISTA Nutrients
    • 2020

    ?-Hydroxybutyrate Increases Exercise Capacity Associated with Changes in Mitochondrial Function in Skeletal Muscle


    • Matías Monsalves Álvarez • Pablo Esteban Morales • Mauricio Castro-Sepulveda • Carlos Andrés Sepúlveda Guzmán • Juan Manuel Rodriguez

    http://dx.doi.org/10.3390/nu12071930

    • REVISTA International Journal of Molecular Sciences
    • 2020

    Moderate Aerobic Exercise Training Prevents the Augmented Hepatic Glucocorticoid Response Induced by High-Fat Diet in Mice


    • Jonatan Dassonvalle • Francisco Díaz-Castro • Camila Donoso-Barraza • Carlos Andrés Sepúlveda Guzmán • Francisco Pino-de la Fuente

    http://dx.doi.org/10.3390/ijms21207582

    • REVISTA International Journal of Molecular Sciences
    • 2020

    Moderate Aerobic Exercise Training Prevents the Augmented Hepatic Glucocorticoid Response Induced by High-Fat Diet in Mice


    • Jonatan Dassonvalle • Francisco Díaz-Castro • Camila Donoso-Barraza • Carlos Andrés Sepúlveda Guzmán • Francisco Pino-de la Fuente

    http://dx.doi.org/10.3390/ijms21207582

    • REVISTA Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids
    • 2019

    Exercise regulates lipid droplet dynamics in normal and fatty liver


    • Francisco Pino-de la Fuente • Laura Quezada • Carlos Andrés Sepúlveda Guzmán • Matías Monsalves Álvarez • Juan M. Rodríguez

    http://dx.doi.org/10.1016/j.bbalip.2019.158519

    • REVISTA International Journal of School Health
    • 2019

    HIITing Health in School: Can High Intensity Interval Training Be a Useful and Reliable Tool for Health on a School-Based Enviroment? A Systematic Review


    • Rafael Zapata-Lamana • Igor Cigarroa Cuevas • Victor Fuentes • Claudio Soto Espindola • Eva Parrado Romero

    http://dx.doi.org/10.5812/intjsh.89829

    • REVISTA Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids
    • 2019

    Exercise regulates lipid droplet dynamics in normal and fatty liver


    • Francisco Pino-de la Fuente • Laura Quezada • Carlos Andrés Sepúlveda Guzmán • Matías Monsalves Álvarez • Juan M. Rodríguez

    http://dx.doi.org/10.1016/j.bbalip.2019.158519

    • REVISTA International Journal of School Health
    • 2019

    HIITing Health in School: Can High Intensity Interval Training Be a Useful and Reliable Tool for Health on a School-Based Enviroment? A Systematic Review


    • Rafael Zapata-Lamana • Igor Cigarroa Cuevas • Victor Fuentes • Claudio Soto Espindola • Eva Parrado Romero

    http://dx.doi.org/10.5812/intjsh.89829

    • REVISTA Revista Brasileira de Medicina do Esporte
    • 2014

    Influência do exercício físico na cognição: uma atualização sobre mecanismos fisiológicos


    • Carlos Merege • Cristiano Robles • Carlos Andrés Sepúlveda Guzmán • André dos Santos Costa • Antonio Herbert Lancha Junior

    http://dx.doi.org/10.1590/1517-86922014200301930

    • REVISTA Revista Brasileira de Medicina do Esporte
    • 2014

    Influência do exercício físico na cognição: uma atualização sobre mecanismos fisiológicos


    • Carlos Merege • Cristiano Robles • Carlos Andrés Sepúlveda Guzmán • André dos Santos Costa • Antonio Herbert Lancha Junior

    http://dx.doi.org/10.1590/1517-86922014200301930

    • MEDICINA Y CIENCIAS APLICADAS AL FÚTBOL. CONMEBOL.
    • 2022

    Demandas bioenergéticas.

    ISBN
    Páginas
    Désde la página , hasta la página
    Idioma
    Español
    Editorial
    Mediterraneo
    Editores
    Roberto Yañez, Sandra Mahecha
    Autores
    Carlos Andrés Sepúlveda Guzmán, Ignacio Orizola-Cáceres
    • MEDICINA Y CIENCIAS APLICADAS AL FÚTBOL. CONMEBOL.
    • 2022

    Evaluación básica y avanzada en el fútbol.

    ISBN
    Páginas
    Désde la página , hasta la página
    Idioma
    Español
    Editorial
    Mediterraneo
    Editores
    Roberto Yañez, Sandra Mahecha
    Autores
    Roberto Meneses-Valdés, Carlos Andrés Sepúlveda Guzmán