Amanda D’espessailles Investigadora Postdoctoral

    Grado Académico

    Doctorado en Nutrición y Alimentos Universidad de Chile (enero 2019)

    Título(s) Profesional

    Licenciada en Ciencias con mención en Biología Universidad de Chile 2011

    Descripción

    Licenciada en Ciencias con mención en Biología, Magister en Ciencias Biológicas y Doctora en Nutrición y Alimentos de la Universidad de Chile. Sus líneas de investigación están relacionadas con los mecanismos moleculares que subyacen a enfermedades crónicas no transmisibles asociadas a obesidad, disfunción del tejido adiposo y enfermedad de hígado graso no alcohólico.

    Higher hepatic advanced glycation end products and liver damage markers are associated with non-alcoholic steatohepatitis

    • Kathleen Maureen Priken Figueroa • Gladys Tapia • CynthiaCadagan • Nicolas Quezada • JavieraTorres

    DOI: http://dx.doi.org/10.1016/j.nutres.2022.04.005

    Dietary alpha- and gamma-tocopherol (1:5 ratio) supplementation attenuates adipose tissue expansion, hepatic steatosis, and expression of inflammatory markers in a high-fat-diet-fed murine model

    • Nevenka Juretic • Ruth Sepúlveda • Amanda D'Espessailles Tapia • Cinthya Cadagan • Manuel De Miguel

    DOI: http://dx.doi.org/10.1016/j.nut.2021.111139

    Hepatic retinaldehyde dehydrogenases are modulated by tocopherols supplementation in mice with hepatic steatosis.

    • Amanda D'Espessailles Tapia • Valeria Campos • Gladys S. Tapia • Paulina Pettinelli • Nevenka Juretic

    DOI: http://dx.doi.org/10.1016/j.nut.2021.111539

    Calcium sensing receptor activation in THP-1 macrophages triggers NLRP3 inflammasome and human preadipose cell inflammation

    • Amanda D'Espessailles Tapia • Natalia Santillana • Cecilia Fuentes • Mariana Cifuentes Köster •

    DOI: http://dx.doi.org/10.1016/j.mce.2019.110654

    Calcium-sensing receptor activates the NLRP3 inflammasome in LS14 preadipocytes mediated by ERK1/2 signaling

    • Amanda D'Espessailles Tapia • Yuli Mora • Cecilia Fuentes • Mariana Cifuentes Köster •

    DOI: http://dx.doi.org/10.1002/jcp.26490

    Rosa Mosqueta Oil Prevents Oxidative Stress and Inflammation through the Upregulation of PPAR-? and NRF2 in C57BL/6J Mice Fed a High-Fat Diet

    • Daniel González-Mañán • Amanda D'Espessailles Tapia • Camila Dossi • Marcela San Martín • Rodrigo Mancilla

    DOI: http://dx.doi.org/10.3945/jn.116.243261

    Calcium sensing receptor effects in adipocytes and liver cells: Implications for an adipose-hepatic crosstalk

    • Villarroel P • Pamela Mattar • Amanda D'Espessailles Tapia • Marco Arrese

    DOI: http://dx.doi.org/10.1016/j.abb.2016.08.017

    <em>n-3</em> LCPUFA in the reversal of hepatic steatosis: the role of ACOX and CAT-1

    • Gladys Tapia • Daniel González-Mañán • Amanda D'Espessailles Tapia • Camila Dossi •

    DOI: http://dx.doi.org/10.3989/gya.0886152

    Dietary Rosa mosqueta (Rosa rubiginosa) oil prevents high diet-induced hepatic steatosis in mice

    • Amanda D'Espessailles Tapia • Camila Dossi • Alejandra Espinosa • Daniel González-Mañán • Gladys Tapia

    DOI: http://dx.doi.org/doi:10.1039/c5fo00741k

    N-3long-chain PUFA supplementation prevents high fat diet induced mouse liver steatosis and inflammation in relation to PPAR-? upregulation and NF-?B DNA binding abrogation

    • Amanda D'Espessailles Tapia • Gladys Tapia • Rodrigo Valenzuela • Alejandra Espinosa • Pamela Romanque

    DOI: http://dx.doi.org/10.1002/mnfr.201300458

    Reversal of high-fat diet-induced hepatic steatosis by n-3 LCPUFA: role of PPAR-? and SREBP-1c

    • Camila Dossi • Gladys Tapia • Alejandra Espinosa • Luis Videla • Amanda D'Espessailles Tapia

    DOI: http://dx.doi.org/10.1016/j.jnutbio.2014.04.011

    Hormonal pretreatment preserves liver regenerative capacity and minimizes inflammation after partial hepatectomy

    • Amanda D'Espessailles Tapia • Camila Dossi • Pedro Leiva • Giomar Intriago • Pamela Romanque

    DOI: http://dx.doi.org/10.1016/S1665-2681(19)31293-1

    Bioconversion of ?-linolenic acid to n-3 LCPUFA and expression of PPAR-alpha, acyl coenzyme A oxidase 1 and carnitine acyl transferase I are incremented after feeding rats with ?-linolenic acid-rich oils

    • Daniel González-Mañán • Gladys Tapia • Gormaz • Juan Guillermo • Amanda D'Espessailles Tapia

    DOI: http://dx.doi.org/10.1039/c2fo30012e

    N-3 Long-Chain Polyunsaturated Fatty Acid Supplementation Significantly Reduces Liver Oxidative Stress in High Fat Induced Steatosis

    • Rodrigo Valenzuela • Alejandra Espinosa • Daniel González-Mañán • Amanda D'Espessailles Tapia • Virginia Fernández

    DOI: http://dx.doi.org/10.1371/journal.pone.0046400

    • ● Noviembre 2020

    Proyecto de investigación SOCHED No 2020-08

    Investigador/a Responsable
    • ● Septiembre 2020

    Producto de divulgación ER190042.

    Co-Investigador/a