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  4. Mauricio Latorre Mora

    Mauricio Latorre Mora ● Profesor Asociado

    Grado Académico

    Doctor en Ciencias, mención Biología Molecular, Celular y Neurociencias, Universidad de Chile.

    Título(s) Profesional

    Ingeniero en Biotecnología Molecular, Universidad de Chile, Chile

    Descripción

    Mauricio Latorre es Ingeniero en Biotecnología Molecular y Doctor en Ciencias de la Universidad de Chile. Su desarrollo profesional se vincula en áreas de Biología de Sistemas y Biotecnología, enfocados principalmente en la construcción y utilización de modelos bacterianos capaces de describir resistencia a metales pesados, patogénesis y procesos de biominería. Actualmente se desarrolla como profesor asistente del Instituto de Ciencias de la Ingeniería de la UOH, investigador asociado de los centros nacionales FONDAP-Center for Genome Regulation, BASAL-Center for Mathematical Modeling y colaborador internacional del departamento de “Infection Diseases” de la Universidad de Texas (E.E.U.U.) y del grupo CNRS-Dyliss de la Université de Rennes (Francia).

    Publicaciones

    34

    Proyectos

    21

    Publicaciones

    Co-occurrence Interaction Networks of Extremophile Species Living in a Copper Mining Tailing

    • Gabriel Galvez • Jaime Ortega • Fernanda Fredericksen • Víctor Aliaga-Tobar • Valentina Parra

    DOI: http://dx.doi.org/10.3389/fmicb.2021.791127

    Genome-scale metabolic models of Microbacterium species isolated from a high altitude desert environment

    • Dinka Mandakovic • Mauricio Latorre •

    DOI: http://dx.doi.org/10.1038/s41598-020-62130-8.

    Integration of biological networks for Acidithiobacillus thiooxidans describes a modular gene regulatory organization of bioleaching pathways

    • María Paz Cortés • Vicente Acuña • Dante Travisany • Anne Siegel • Alejandro Maass

    DOI: http://dx.doi.org/10.3389/fmolb.2019.00155.

    Genome-wide analysis of in vivo CcpA binding with and without its key co-factor HPr in the major human pathogen group A Streptococcus

    • Sruti DebRoy • Mauricio Latorre • Samuel Shelburne •

    DOI: http://dx.doi.org/10.3389/fmolb.2019.00155.

    Chronic copper treatment prevents the liver critical balance transcription response induced by acetaminophen

    • Mauricio Latorre • Jason L. Burkhead • Christian Hodar • Miguel Arredondo • Mauricio Gonzalez Canales

    DOI: http://dx.doi.org/10.1016/j.jtemb.2019.02.007

    Antimicrobial sensing coupled with cell membrane remodeling mediates antibiotic resistance and virulence in Enterococcus faecalis.

    • Ayesha Khan • Mauricio Latorre • Cesar A Arias •

    DOI: http://dx.doi.org/10.1073/pnas.1916037116.

    The Combined Effect of Cold and Copper Stresses on the Proliferation and Transcriptional Response of Listeria monocytogenes

    • Ana María Quesille-Villalobos • Angel Parra • Felipe Maza • Paola Navarrete • Mauricio Gonzalez Canales

    DOI: http://dx.doi.org/10.3389/fmicb.2019.00612

    Generation and robustness of Boolean networks to model Clostridium difficile infection

    • Dante Travisany • Eric Goles • Mauricio Latorre • María Paz Cortés • Alejandro Maass

    DOI: http://dx.doi.org/10.3389/fmicb.2019.00612

    Structure and co-occurrence patterns in microbial communities under acute environmental stress reveal ecological factors fostering resilience

    • Dinka Mandakovic • Claudia Macarena Rojas Alvarado • Jonathan Maldonado • Mauricio Latorre • Dante Travisany

    DOI: http://dx.doi.org/10.1038/s41598-018-23931-0

    Altered zinc balance in the Atp7b-/- mouse reveals a mechanism of copper toxicity in Wilson disease

    • Kelsey A. Meacham • María Paz Cortés • Eve M. Wiggins • Alejandro Maass • Mauricio Latorre

    DOI: http://dx.doi.org/10.1039/c8mt00199e

    Traceability, reproducibility and wiki-exploration for "à-la-carte" reconstructions of genome-scale metabolic models

    • Méziane Aite • Mauricio Latorre • Anne Siegel •

    DOI: http://dx.doi.org/10.1371/journal.pcbi.1006146

    Codon usage bias reveals genomic adaptations to environmental conditions in an acidophilic consortium

    • Andrew Hart • María Paz Cortés • Mauricio Latorre • Servet Martinez •

    DOI: http://dx.doi.org/10.1371/journal.pone.0195869

    Synthesis and Antibacterial Activity of Metal(loid) Nanostructures by Environmental Multi-Metal(loid) Resistant Bacteria and Metal(loid)-Reducing Flavoproteins

    • Maximiliano Figueroa • Valentina Fernandez • Mauricio Arenas-Salinas • Diego Ahumada • Claudia Muñoz-Villagrán

    DOI: http://dx.doi.org/10.3389/fmicb.2018.00959

    The Role of Fur in the Transcriptional and Iron Homeostatic Response of Enterococcus faecalis

    • Mauricio Latorre • Daniela Quenti • Dante Travisany • Kavindra V. Singh • Barbara E. Murray

    DOI: http://dx.doi.org/10.3389/fmicb.2018.01580

    Cobalamin cbiP mutant shows decreased tolerance to low temperature and copper stress in Listeria monocytogenes

    • Mauricio Latorre • Angélica Reyes-Jara •

    DOI: http://dx.doi.org/10.1186/s40659-022-00376-4

    Estrogen signaling as a bridge between the nucleus and mitochondria in cardiovascular diseases

    • Emanuel Guajardo-Correa • Juan Francisco Silva-Agüero • Mauricio Latorre • Valentina Parra •

    DOI: http://dx.doi.org/10.3389/fcell.2022.968373

    Generation and robustness of Boolean networks to model Clostridium difficile infection

    • Mauricio Latorre • Dante Travisany • Eric Goles • María-Paz Cortés • Dra. Barbara E. Murray

    DOI: http://dx.doi.org/10.1007/s11047-019-09730-0

    Identification of reference genes for quantitative real-time PCR studies in human cell lines under copper and zinc exposure

    • Mauricio Latorre •

    DOI: http://dx.doi.org/10.1007/s10534-016-9965-x

    Structural and functional analysis of the ASM p.Ala359Asp mutant that causes acid sphingomyelinase deficiency

    • Mauricio Latorre •

    DOI: http://dx.doi.org/10.1016/j.bbrc.2016.09.096

    The bioleaching potential of a bacterial consortium

    • Mauricio Latorre •

    DOI: http://dx.doi.org/10.1016/j.biortech.2016.07.012

    A Multi-Serotype Approach Clarifies the Catabolite Control Protein A Regulon in the Major Human Pathogen Group A Streptococcus

    • Mauricio Latorre •

    DOI: http://dx.doi.org/10.1038/srep32442

    Putative bacterial interactions from metagenomic knowledge with an integrative systems ecology approach

    • Mauricio Latorre •

    DOI: http://dx.doi.org/10.1002/mbo3.315

    Transcriptional activation of glutathione pathways and role of glucose homeostasis during copper imbalance

    • Mauricio Latorre •

    DOI: http://dx.doi.org/10.1007/s10534-015-9834-z

    Synergistic effect of copper and low temperature over Listeria monocytogenes

    • Mauricio Latorre •

    DOI: http://dx.doi.org/10.1007/s10534-015-9891-3

    Global transcriptional responses of Acidithiobacillus ferrooxidans Wenelen under different sulfide minerals

    • Mauricio Latorre •

    DOI: http://dx.doi.org/10.1016/j.biortech.2015.09.110

    Complete genome sequence of Microbacterium sp. CGR1, bacterium tolerant to wide abiotic conditions isolated from the Atacama Desert

    • Mauricio Latorre •

    DOI: http://dx.doi.org/10.1016/j.jbiotec.2015.10.020

    Nutrigenomics analysis reveals that copper deficiency and dietary sucrose up-regulate inflammation, fibrosis and lipogenic pathways in a mature rat model of nonalcoholic fatty liver disease

    • Mauricio Latorre •

    DOI: http://dx.doi.org/10.1016/j.jnutbio.2015.04.009

    Interplay between copper and zinc homeostasis through the transcriptional regulator Zur in Enterococcus faecalis

    • Mauricio Latorre •

    DOI: http://dx.doi.org/10.1039/c5mt00043b

    A new genome of Acidithiobacillus thiooxidans provides insights into adaptation to a bioleaching environment

    • Mauricio Latorre •

    DOI: http://dx.doi.org/10.1016/j.resmic.2014.08.004

    Enterococcus faecalis reconfigures its transcriptional regulatory network activation at different copper levels

    • Mauricio Latorre •

    DOI: http://dx.doi.org/10.1039/c3mt00288h

    Transcriptomic response of Enterococcus faecalis to iron excess

    • Mauricio Latorre •

    DOI: http://dx.doi.org/10.1007/s10534-012-9539-5

    Genome wide identification of Acidithiobacillus ferrooxidans (ATCC 23270) transcription factors and comparative analysis of ArsR and MerR metal regulators

    • Mauricio Latorre •

    DOI: http://dx.doi.org/10.1007/s10534-011-9484-8

    CutC is induced late during copper exposure and can modify intracellular copper content in Enterococcus faecalis

    • Mauricio Latorre •

    DOI: http://dx.doi.org/10.1016/j.bbrc.2011.02.109

    Genome-wide transcriptome analysis of the adaptive response of Enterococcus faecalis to copper exposure

    • Mauricio Latorre •

    DOI: http://dx.doi.org/10.1007/s10534-010-9356-7

    Proyectos

    • ● Marzo 2022

    Centro de Modelamiento Matemático

    • ● Diciembre 2021

    Systems Biology Center for the study of extremophile communities from mining tailings. Anillo ACT210004.

    • ● Junio 2021

    Estudio de especies bacterianas con potenciales en biotecnología: Aplicaciones en minería y agroindustria.

    • ● Noviembre 2020

    Laboratorio de diagnóstico Universidad de O’Higgins ETAPA 3

    Investigador/a Responsable
    • ● Septiembre 2020

    Laboratorio de diagnóstico Universidad de O’Higgins ETAPA 2

    Investigador/a Responsable
    • ● Julio 2020

    Laboratorio de diagnóstico Universidad de O’Higgins. ETAPA 1

    Investigador/a Responsable
    • ● Abril 2020

    Marcadores Metabólicos de Pronóstico de Severidad para Pacientes Covid-19.

    • ● Marzo 2019

    Laboratorio Biominero para la Región de O’Higgins

    • ● Marzo 2019

    Non-coding RNA global transcriptional regulatory network in Enterococcus faecalis.

    Investigador/a Responsable
    • ● Marzo 2019

    RCAN1 trisomy and the control of PINK1 levels in the survival of human Down’s syndrome induced pluripotent stem cells (iPSC) and iPSC-derived cardiomyocytes

    • ● Marzo 2019

    Transcriptional Networks for Mitochondrial Dynamics related to Human Cardiomyocyte Dysfunction.

    • ● Marzo 2018

    Entendiendo la complejidad metabólica y nutricional de frutos en poscosecha: una perspectiva integradora desde la Biología de Sistemas.

    • ● Marzo 2018

    Estudio de especies bacterianas nativas de importancia nacional mediante estrategias de Biología de Sistemas.

    Investigador/a Responsable
    • ● Mayo 2017

    EUROPEAN COMMISSION REA: MILEAGE Nº734931.

    • ● Marzo 2017

    Synergistic transcriptional response of Listeria monocytogenes to low temperature and copper.

    • ● Marzo 2016

    Centro de Modelamiento Matemático (CMM)

    • ● Marzo 2016

    Role of Fur in the systemic response of Enterococcus faecalis and its impact on in vivo infectiveness under different nutritional status of iron.

    Investigador/a Responsable
    • ● Marzo 2015

    Centro de Regulación del Genoma (CRG)

    • ● Marzo 2015

    Metal metabolism in soil bacterial communities from an extreme environment: A comparative genomics analysis.

    • ● Marzo 2015

    Sistema biotecnológico de extracción de tierras raras presentes en relaves mineros.

    • ● Marzo 2015

    Transferencia Laboratorio Ecosistemas de Humedales