Denisse Valladares Ide Profesora Asistente

    Grado Académico

    Ciencias Biomédicas, Universidad de Chile / Magister en Formación Docente para la Enseñanza Universitaria, Finis Terrae

    Título(s) Profesional

    Bioquímica, Universidad Austral de Chile

    Descripción

    Ciencias Biomédicas, Universidad de Chile / Magister en Formación Docente para la Enseñanza Universitaria, Finis Terrae.

    High extracellular ATP levels released through pannexin-1 channels mediate inflammation and insulin resistance in skeletal muscle fibers of diet induced obese mice

    • Gonzalo Jorquera • Roberto Meneses-Valdés • Giovanni Rosales-Soto • Denisse Valladares • Cristian Campos

    DOI: http://dx.doi.org/10.1007/s00125-021-05418-2

    Changes in pulmonary and plasma Oxidative Stress and Inflammation Following Eccentric and Concentric Cycling in Stable COPD Patients

    • Denisse Valladares • Maria José Bravo • Ana Carvajal • Oscar F. Araneda • Marcelo Tuesta

    DOI: http://dx.doi.org/10.1007/s00421-021-04652-1

    NLRP3 Inflammasome: Potential Role in Obesity Related Low-Grade Inflammation and Insulin Resistance in Skeletal Muscle

    • Gonzalo Jorquera • Javier Russell • Matías Monsalves Álvarez • Gonzalo Cruz • Denisse Valladares

    DOI: http://dx.doi.org/10.3390/ijms22063254

    Moderate Exercise in Spontaneously Hypertensive Rats Is Unable to Activate the Expression of Genes Linked to Mitochondrial Dynamics and Biogenesis in Cardiomyocytes

    • Clara Quiroga • Georthan Mancilla • Ingrid Oyarzun • Anita Tapia • Mia Caballero

    DOI: http://dx.doi.org/10.3389/fendo.2020.00546

    Changes in oxidative stress, inflammation and muscle damage markers following eccentric versus concentric cycling in older adults

    • Roberto González-Bartholin • Karen Mackay • Denisse Valladares • Hermann Zbinden-Foncea • Kazunori Nosaka

    DOI: http://dx.doi.org/10.1007/s00421-019-04213-7

    Defective fasting-induced PKA activation impairs adipose tissue glycogen degradation in obese Zucker rats

    • Marcelo Flores • Jennifer Trieu • Timur Naim • Denisse Valladares • Hermann Zbinden-Foncea

    DOI: http://dx.doi.org/10.1038/s41366-019-0327-y

    Activation of protein synthesis, regeneration, and MAPK signaling pathways following repeated bouts of eccentric cycling

    • Denisse Valladares • Luis Peñailillo • Nicolás Collao • Hugo Marambio • Louise Deldicque

    DOI: http://dx.doi.org/10.1152/ajpendo.00216.2019

    IP3 receptor blockade restores autophagy and mitochondrial function in skeletal muscle fibers of dystrophic mice

    • Denisse Valladares • Yildy Utreras-Mendoza • Cristian Campos • Camilo Morales • Alexis Diaz-Vegas

    DOI: http://dx.doi.org/10.1016/j.bbadis.2018.08.042

    Mitochondrial Calcium Increase Induced by RyR1 and IP3R Channel Activation After Membrane Depolarization Regulates Skeletal Muscle Metabolism

    • Alexis R. Díaz-Vegas • Alex Cordova • Denisse Valladares • Paola Llanos • Cecilia Hidalgo

    DOI: http://dx.doi.org/10.3389/fphys.2018.00791

    Characterization of a multiprotein complex involved in excitation-transcription coupling of skeletal muscle

    • Manuel Arias-Calderón • Gonzalo Almarza • Alexis Diaz-Vegas • Ariel Contreras-Ferrat • Denisse Valladares

    DOI: http://dx.doi.org/10.1186/s13395-016-0087-5

    GSK-3?/NFAT Signaling Is Involved in Testosterone-Induced Cardiac Myocyte Hypertrophy

    • Javier Duran • Cesar Oyarce • Mario Pavez • Denisse Valladares • Carla Basualto-Alarcon

    DOI: http://dx.doi.org/10.1371/journal.pone.0168255

    NOX2 Inhibition Impairs Early Muscle Gene Expression Induced by a Single Exercise Bout

    • Carlos Henríquez-Olguín • Alexis Diaz-Vegas • Yildy Utreras-Mendoza • Cristian Campos • Manuel Arias-Calderón

    DOI: http://dx.doi.org/10.3389/fphys.2016.00282

    Altered ROS production, NF-?B activation and interleukin-6 gene expression induced by electrical stimulation in dystrophic mdx skeletal muscle cells

    • Carlos Henríquez-Olguín • Francisco Altamirano • Denisse Valladares • José R. López • Paul D. Allen

    DOI: http://dx.doi.org/10.1016/j.bbadis.2015.03.012

    Nifedipine Treatment Improves Muscle Function in Mdx Mice

    • Francisco Altamirano • Denisse Valladares • Carlos Henríquez-Olguín • Mariana Casas • José R. López

    DOI: http://dx.doi.org/10.1016/j.bpj.2013.11.4014

    Electrical Stimuli Are Anti-Apoptotic in Skeletal Muscle via Extracellular ATP. Alteration of This Signal in Mdx Mice Is a Likely Cause of Dystrophy

    • Denisse Valladares • Gonzalo Almarza • Ariel Contreras • Mario Pavez • Sonja Buvinic

    DOI: http://dx.doi.org/10.1371/journal.pone.0075340

    Nifedipine Treatment Reduces Resting Calcium Concentration, Oxidative and Apoptotic Gene Expression, and Improves Muscle Function in Dystrophic mdx Mice

    • Francisco Altamirano • Denisse Valladares • Carlos Henríquez-Olguín • Mariana Casas • José R. López

    DOI: http://dx.doi.org/10.1371/journal.pone.0081222

    Do Adenosine Receptors Offer New Therapeutic Options for Diabetic Nephropathy?

    • Rody Martin • Denisse Valladares • Horacio Roa • Evelin Troncoso • Luis Sobrevia

    DOI: http://dx.doi.org/10.2174/157016109789043964

    Adenosine A2B receptor mediates an increase on VEGF-A production in rat kidney glomeruli

    • Denisse Valladares • C. Quezada • P. Montecinos • Concha • A.J. Yañez

    DOI: http://dx.doi.org/10.1016/j.bbrc.2007.11.113

    Effects of eccentric, concentric and eccentric/concentric training on muscle function and mass, functional performance, cardiometabolic health, quality of life and molecular adaptations of skeletal muscle in COPD patients: a multicentre randomised trial

    • Luis Peñailillo • Denisse Valladares • Sebastián Jannas Vela • Marcelo Flores • Mauricio Jalón

    DOI: http://dx.doi.org/10.1186/s12890-022-02061-4

    • ● Abril 2022

    Fortalecimiento de estrategias comunitarias de promoción de la salud, prevención y tratamiento temprano y oportuno de enfermedades crónicas no transmisibles con foco en actividad física y nutrición saludable

    Co-Investigador/a
    • ● Diciembre 2021

    Creacion de imagenes de super-resolucion ultrasonicas en placentas humanas ex vivo

    Co-Investigador/a
    • ● Diciembre 2021

    “Divas de la Ciencia” Mujeres del Pasado Inspirando al Futuro

    Co-Investigador/a
    • ● Julio 2021

    Creación de imágenes de super-resolución ultrasónicas en placentas humanas ex-vivo

    Co-Investigador/a
    • ● Abril 2021

    Effects of eccentric, concentric and eccentric/concentric training on muscle function and mass, functional performance, cardiometabolic health, quality of life and molecular adaptations of skeletal muscle in COPD patients: a multicenter randomized trial

    Co-Investigador/a
    • ● Noviembre 2019

    Exercise stimulates autophagy by downregulation of NOX2 activity improving young and aged human skeletal muscle function

    Co-Investigador/aCo-Investigador/a
    • ● Octubre 2013

    Modulación de la autofagia por el receptor de inositol trifosfato (IP3R) en distrofia muscular de Duchenne

    Co-Investigador/aCo-Investigador/a
    • ● Octubre 2013

    No Whey: Lácteos altos en proteína y ejercicio de resistencia para la mejora de la composición corporal y función muscular de personas mayores.

    Responsable Alterno