{"id":348,"date":"2022-04-26T00:44:39","date_gmt":"2022-04-26T03:44:39","guid":{"rendered":"https:\/\/www.uoh.cl\/investigacion\/?page_id=348"},"modified":"2023-01-10T15:55:32","modified_gmt":"2023-01-10T18:55:32","slug":"proyectos","status":"publish","type":"page","link":"https:\/\/www.uoh.cl\/investigacion\/proyectos\/","title":{"rendered":"Proyectos"},"content":{"rendered":"<div class=\"wpb-content-wrapper\"><p>[vc_section el_class=&#8221;container mx-auto align-items-center circle&#8211;pattern&#8221; css=&#8221;.vc_custom_1673376913144{padding-top: 3rem !important;}&#8221;][vc_row][vc_column][vc_wp_custommenu nav_menu=&#8221;5&#8243;]<div class=\"breadcrumb\"><ol itemscope itemtype=\"https:\/\/schema.org\/BreadcrumbList\"><li itemprop=\"itemListElement\" itemscope itemtype=\"https:\/\/schema.org\/ListItem\"><a itemprop=\"item\" href=\"http:\/\/www.uoh.cl\"><span itemprop=\"name\">Inicio<\/span><\/a><meta itemprop=\"position\" content=\"1\" \/><li itemprop=\"itemListElement\" itemscope itemtype=\"https:\/\/schema.org\/ListItem\"><a itemprop=\"item\" href=\"https:\/\/www.uoh.cl\/investigacion\"><span itemprop=\"name\">Investigaci\u00f3n<\/span><\/a><meta itemprop=\"position\" content=\"2\" \/><li itemprop=\"itemListElement\" itemscope itemtype=\"https:\/\/schema.org\/ListItem\"><span itemprop=\"name\">Proyectos <\/span><meta itemprop=\"position\" content=\"3\" \/><\/ol><\/div><div class=\"uoh_title_component-container\"><h1 class=\"title title--ms d-inline-block title--decorator  big\">Proyectos<\/h1><\/div><div class=\"row filter__row m-0 horizontal\"> <form class=\"filter__form p-0 row m-0\" action=\"https:\/\/www.uoh.cl\/investigacion\/wp-admin\/admin-ajax.php\" method=\"post\" id=\"filter\"><div class=\"col-12 col-md-6 filter__container-input p-0\"><div class=\"filter__icon-search\"><svg enable-background=\"new 0 0 32 32\" id=\"Editable-line\" version=\"1.1\" viewBox=\"0 0 32 32\" xml:space=\"preserve\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\"><circle cx=\"14\" cy=\"14\" fill=\"none\" id=\"XMLID_42_\" r=\"9\" stroke=\"#000000\" stroke-linecap=\"round\" stroke-linejoin=\"round\" stroke-miterlimit=\"10\" stroke-width=\"2\"><\/circle><line fill=\"none\" id=\"XMLID_44_\" stroke=\"#000000\" stroke-linecap=\"round\" stroke-linejoin=\"round\" stroke-miterlimit=\"10\" stroke-width=\"2\" x1=\"27\" x2=\"20.366\" y1=\"27\" y2=\"20.366\"><\/line><\/svg><\/div><input type=\"text\" class=\"filter__input\" placeholder=\"Buscar Proyectos\" name=\"filter__form-text\" autocomplete=\"off\"\/><\/div><div class=\"col-12 col-md-6 row m-0 justify-content-end p-0\"><input type=\"hidden\" name=\"action\" value=\"uoh_filter\" \/><input type=\"hidden\" name=\"posttype\" value=\"projects\" \/><div class=\"loading\"><svg version=\"1.1\" id=\"L5\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" x=\"0px\" y=\"0px\" viewBox=\"0 0 100 100\" enable-background=\"new 0 0 0 0\" xml:space=\"preserve\">\n                  <circle fill=\"#42a0f8\" stroke=\"none\" cx=\"6\" cy=\"50\" r=\"6\">\n                    <animateTransform attributeName=\"transform\" dur=\"1s\" type=\"translate\" values=\"0 15 ; 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el_class=&#8221;p-md-0&#8243;][vc_row el_class=&#8221;container mx-auto p-md-0&#8243;][vc_column width=&#8221;1\/4&#8243;]<div class=\"row filter__row margin-box-vertical box-vertical\"> <form  p-0 row m-0\" action=\"https:\/\/www.uoh.cl\/investigacion\/wp-admin\/admin-ajax.php\" method=\"post\" id=\"filter__vertical\"><div class=\"select__for-authors\">\n                                <span> Ordenar Resultados<\/span>\n\n                                <div class=\"select__for-authors-input\">\n                                    <select name=\"order\" id=\"order\" class=\"select__author mb-4\">\n                                        <option value=\"desc\">M\u00e1s Nuevos<\/option>\n                                        <option value=\"asc\">M\u00e1s Antiguos<\/option>\n                                    <\/select>\n                                <\/div>\n                            <\/div><div class=\"select__for-authors mb-2\"><span> Filtrar por autor<\/span><input type=\"text\" id=\"autocomplete__authors\" name=\"author\" placeholder=\"Buscar autor\" autocomplete=\"off\"><div class=\"loading loading-author\"><svg version=\"1.1\" id=\"L5\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" x=\"0px\" y=\"0px\" viewBox=\"0 0 100 100\" enable-background=\"new 0 0 0 0\" xml:space=\"preserve\">\n                  <circle fill=\"#42a0f8\" stroke=\"none\" cx=\"6\" cy=\"50\" r=\"6\">\n                    <animateTransform attributeName=\"transform\" dur=\"1s\" type=\"translate\" values=\"0 15 ; 0 -15; 0 15\" repeatCount=\"indefinite\" begin=\"0.1\"><\/animateTransform>\n                  <\/circle>\n                  <circle fill=\"#42a0f8\" stroke=\"none\" cx=\"30\" cy=\"50\" r=\"6\">\n                    <animateTransform attributeName=\"transform\" dur=\"1s\" type=\"translate\" values=\"0 10 ; 0 -10; 0 10\" repeatCount=\"indefinite\" begin=\"0.2\"><\/animateTransform>\n                  <\/circle>\n                  <circle fill=\"#42a0f8\" stroke=\"none\" cx=\"54\" cy=\"50\" r=\"6\">\n                    <animateTransform attributeName=\"transform\" dur=\"1s\" type=\"translate\" values=\"0 5 ; 0 -5; 0 5\" repeatCount=\"indefinite\" begin=\"0.3\"><\/animateTransform>\n                  <\/circle>\n                <\/svg><\/div><div id=\"user__option\">\n                        <li class=\"academic-list pe-4 py-2 inline\"><a target=\"__blank\" href=\"\"><img decoding=\"async\" width=\"150\" height=\"150\" src=\"\" class=\"attachment-thumbnail size-thumbnail wp-post-image\" alt=\"\" ><\/a><h5 class=\"name-user-option\"><em class=\"d-block font-style-normal name-user-option-em\"> <\/em><\/h5><\/li>\n                        <div class=\"btn-close\"><\/div>\n                        <\/div><div id=\"someElem\"><\/div><\/div><div class=\"tax_select mt-4\">\n                    <span class=\"col-12 p-0  d-block\"> Filtrar por Categor\u00eda<\/span><div class=\"select__for-authors-input\"><select name=\"tax\" class=\"select__author mb-4\"><option value=\"-1\" class=\"filter__option-title\">Seleccionar <\/option><\/select><\/div><\/div><div class=\"tags-cloud mt-2 d-block mb-4\">\n                    <span class=\"col-12 p-0 mb-3 d-block\"> Filtrar por tema de int\u00e9res<\/span><\/div><\/div><input type=\"hidden\" name=\"action\" value=\"uoh_filter\" \/><input type=\"hidden\" name=\"posttype\" value=\"projects\" \/>[\/vc_column][vc_column width=&#8221;3\/4&#8243;]<link rel=\"stylesheet\" id=\"font-awesome-css\" href=\"https:\/\/cdnjs.cloudflare.com\/ajax\/libs\/font-awesome\/6.5.1\/css\/all.min.css\" type=\"text\/css\" media=\"all\"><div class=\"row m-0 p-0\"><div class=\"col-12 col-md-9 pt-5 pt-md-0 px-md-0 \"><\/div><\/div><div class=\"content-holder row m-0 p-0 aling-items-center pt-5 pb-5 \"><div class=\"row  large--swipper-content p-0 \"><div class=\"\"><div class=\"  circle--pattern-bottom-large col-sm-12 col-md-12 img-article\"><div class=\"holder-publish col-md-12\" style=\"border-bottom: 1px solid #EFB956\"><div class=\"content-holder h-100 component-border overflow-hidden row m-0 p-4 aling-items-center\"><ul class=\"p-0 list-style-none\"><li class=\"p-0 ms-1\"><i class=\"fa fa-regular fa-calendar fa-fw ms-1\"><\/i>Abril 2026 - Mayo 2029<\/li><\/ul><div class=\"caption col-12 p-0 col-md-12 row m-0 align-items-center\"><div class=\"px-md-1\"><small class=\"badge rounded-pill fw-semibold\" style=\"background-color:#EFB956 !important; color:#FFF\">Adjudicado<\/small><small class=\"ms-2 badge rounded-pill fw-semibold\" style=\"background-color:#F0F1F3 !important; color:#797979\"><i class=\"fa fa-solid fa-lg fa-money-check-dollar fa-fw me-1\"><\/i>Gobierno Regional - GORE<\/small>\n                            <div class=\"accordion accordion-flush\" id=\"26379\">\n                                <div class=\"accordion-item\">\n                                    <h3 class=\"my-0 small-space pt-2 title-ss text-decoration-none accordion-header\">\n                                        <a role=\"button\" class=\"bg-transparent p-0\" href=\"\">\n                                            <i class=\"fas fa-solid fa-link fa-fw me-2\"><\/i>\n                                            Fortaleciendo la protecci\u00f3n del humedal Bucalemu: Transferencia de herramientas para la gesti\u00f3n, monitoreo y desarrollo sostenible\n                                        <\/a><\/h3>\n                                    <div id=\"collapse-26379\" class=\"accordion-collapse collapse\" data-bs-parent=\"#26379\">\n                                        <div class=\"accordion-body p-0 pt-4 pb-4\">\n                                            [vc_section el_class=\"container mx-auto align-items-center circle--pattern\" css=\".vc_custom_1648956589196{padding-top: 3rem !important;}\"][vc_row el_class=\"pb-5\"][vc_column][vc_wp_custommenu nav_menu=\"6\"][uoh_breadcrumb_component automatic_breadcrumb=\"true\"][uoh_title_component title_dropdown=\"big\" title_decorator=\"true\"]{{title}}[\/uoh_title_component][vc_column_text css=\"\"]En el marco del diagn\u00f3stico territorial participativo realizado para el humedal Bucalemu, los beneficiarios identificaron necesidades prioritarias para mejorar la gesti\u00f3n integral del humedal, considerando su importancia como \u00e1rea protegida y las actividades antr\u00f3picas asociadas. Entre las propuestas m\u00e1s destacadas se encuentran:\r\n1.\tFortalecer la gobernanza local: Los actores locales se\u00f1alaron la necesidad de establecer un plan de gesti\u00f3n municipal que permita una mejor coordinaci\u00f3n entre las partes interesadas y que priorice acciones concretas para la conservaci\u00f3n y uso sostenible del humedal.\r\n2.\tImplementar programas educativos y de difusi\u00f3n: Se propuso incluir a la comunidad y a los colegios locales en actividades de educaci\u00f3n ambiental, sensibilizaci\u00f3n sobre la importancia del humedal y difusi\u00f3n de buenas pr\u00e1cticas de manejo sostenible.\r\n3.\tCapacitaci\u00f3n en monitoreo ambiental: Los participantes destacaron la necesidad de contar con herramientas y conocimientos t\u00e9cnicos para monitorear y gestionar el humedal de manera aut\u00f3noma y sostenible.\r\n4.\tZonificaci\u00f3n y regulaci\u00f3n de actividades: Identificaron la importancia de delimitar \u00e1reas para uso tur\u00edstico, conservaci\u00f3n estricta y actividades productivas de bajo impacto, para minimizar los efectos de las actividades humanas sobre el ecosistema.\r\nLa Universidad de O\u0092Higgins se compromete a incorporar estas propuestas como ejes centrales en el proyecto, apoyando al municipio en el desarrollo de su plan de gesti\u00f3n mediante las siguientes acciones concretas:\r\n\u0095\tGenerar informaci\u00f3n cient\u00edfica confiable a trav\u00e9s del Laboratorio de Ecosistemas de Humedales, la cual servir\u00e1 como base t\u00e9cnica para el diagn\u00f3stico sectorial y la planificaci\u00f3n.\r\n\u0095\tFacilitar talleres participativos para definir los objetos de conservaci\u00f3n y metas del plan, as\u00ed como estrategias espec\u00edficas para su implementaci\u00f3n.\r\n\u0095\tTransferir herramientas de monitoreo ambiental y capacitar a actores locales, asegurando que puedan realizar un seguimiento continuo de los indicadores del plan.\r\n\u0095\tDise\u00f1ar materiales educativos y desarrollar campa\u00f1as de difusi\u00f3n que fortalezcan la conexi\u00f3n entre la comunidad y el humedal.\r\n\"Como resultado del proceso de diagn\u00f3stico territorial participativo, los beneficiarios identificaron diversas iniciativas clave para fortalecer la gesti\u00f3n del humedal Bucalemu y promover su desarrollo sostenible. Entre las propuestas m\u00e1s destacadas se incluyen:\r\n1.\tCharlas informativas: Estas actividades sensibilizar\u00e1n a la comunidad sobre la importancia del humedal, destacando su biodiversidad y los beneficios de su conservaci\u00f3n. Las charlas incluir\u00e1n informaci\u00f3n t\u00e9cnica y relevante para fomentar un manejo m\u00e1s sostenible del ecosistema.\r\n2.\tProgramas educativos con colegios locales: Se implementar\u00e1n talleres pr\u00e1cticos y actividades educativas para involucrar a estudiantes en la conservaci\u00f3n del humedal, inspirando un sentido de pertenencia y responsabilidad hacia el ecosistema.\r\n3.\tCapacitaciones especializadas: Funcionarios municipales y algunos actores clases recibir\u00e1n formaci\u00f3n en gesti\u00f3n sostenible, incluyendo monitoreo ambiental y pr\u00e1cticas de bajo impacto, para fortalecer sus capacidades en el manejo del humedal.\r\n4.\tActividades de difusi\u00f3n y sensibilizaci\u00f3n: Campa\u00f1as de comunicaci\u00f3n y material informativo promover\u00e1n el turismo responsable y orientar\u00e1n a los visitantes hacia pr\u00e1cticas respetuosas con el ecosistema.\r\n5.\tFortalecimiento de los peque\u00f1os productores locales: Se desarrollar\u00e1n actividades espec\u00edficas para capacitar a productores en pr\u00e1cticas sostenibles y promocionar sus productos como parte de una estrategia de turismo responsable, fortaleciendo su conexi\u00f3n con el humedal.\r\n\r\nEl Laboratorio de Ecosistemas de Humedales de la Universidad de O\u0092Higgins aportar\u00e1 informaci\u00f3n cient\u00edfica y herramientas t\u00e9cnicas esenciales para sustentar estas iniciativas, especialmente en lo relacionado con el diagn\u00f3stico del ecosistema, el dise\u00f1o de protocolos de monitoreo y la generaci\u00f3n de indicadores clave para evaluar el impacto de las acciones implementadas. De esta forma, la Universidad de O\u0092Higgins se compromete a incorporar estas propuestas en la iniciativa, asegurando su implementaci\u00f3n como parte de una estrategia integral de transferencia de conocimiento y gesti\u00f3n sostenible en colaboraci\u00f3n con los actores locales y otras instituciones relevantes[\/vc_column_text][\/vc_column][\/vc_row][\/vc_section][vc_section css=\".vc_custom_1649209804184{background-color: #f6faff !important;}\" el_class=\"p-md-0 pt-md-5\"][vc_row el_class=\"container mx-auto align-items-center p-md-0 pt-5\"][vc_column el_class=\"p-0\"][\/vc_column][\/vc_row][\/vc_section][vc_section css=\".vc_custom_1649210787516{background-color: #f6faff !important;}\" el_class=\"p-md-0 pt-md-5 pb-md-5\"][vc_row el_class=\"container mx-auto align-items-center\"][vc_column][\/vc_column][\/vc_row][\/vc_section]\n                                        <\/div>\n                                    <\/div>\n                                <\/div>\n                            <\/div><div class=\"mt-3\"><i class=\"fas fa-solid fa-user-tag fa-fw me-2\"><\/i><small class=\"text-muted\">Investigador\/a Responsable<\/small><\/div><span class=\"caption-field-publish\"><\/span><\/div><\/div><\/div><\/div><\/div><div class=\"  circle--pattern-bottom-large col-sm-12 col-md-12 img-article\"><div class=\"holder-publish col-md-12\" style=\"border-bottom: 1px solid #EFB956\"><div class=\"content-holder h-100 component-border overflow-hidden row m-0 p-4 aling-items-center\"><ul class=\"p-0 list-style-none\"><li class=\"p-0 ms-1 me-2\"><i class=\"fa fa-solid fa-id-card-clip fa-fw\"><\/i> 1261124<\/li><li class=\"p-0 ms-1\"><i class=\"fa fa-regular fa-calendar fa-fw ms-1\"><\/i>Abril 2026 - Marzo 2029<\/li><\/ul><div class=\"caption col-12 p-0 col-md-12 row m-0 align-items-center\"><div class=\"px-md-1\"><small class=\"badge rounded-pill fw-semibold\" style=\"background-color:#EFB956 !important; color:#FFF\">Adjudicado<\/small><small class=\"ms-2 badge rounded-pill fw-semibold\" style=\"background-color:#F0F1F3 !important; color:#797979\"><i class=\"fa fa-solid fa-lg fa-money-check-dollar fa-fw me-1\"><\/i>Agencia Nacional de Investigaci\u00f3n y Desarrollo - ANID<\/small>\n                            <div class=\"accordion accordion-flush\" id=\"27125\">\n                                <div class=\"accordion-item\">\n                                    <h3 class=\"my-0 small-space pt-2 title-ss text-decoration-none accordion-header\">\n                                        <a role=\"button\" class=\"bg-transparent p-0\" href=\"\">\n                                            <i class=\"fas fa-solid fa-link fa-fw me-2\"><\/i>\n                                            Los cuidados en perspectiva territorial: estudio comparativo sobre corresponsabilidad de g\u00e9nero, salud mental y uso del tiempo en la agricultura familiar\n                                        <\/a><\/h3>\n                                    <div id=\"collapse-27125\" class=\"accordion-collapse collapse\" data-bs-parent=\"#27125\">\n                                        <div class=\"accordion-body p-0 pt-4 pb-4\">\n                                            [vc_section el_class=\"container mx-auto align-items-center circle--pattern\" css=\".vc_custom_1648956589196{padding-top: 3rem !important;}\"][vc_row el_class=\"pb-5\"][vc_column][vc_wp_custommenu nav_menu=\"6\"][uoh_breadcrumb_component automatic_breadcrumb=\"true\"][uoh_title_component title_dropdown=\"big\" title_decorator=\"true\"]{{title}}[\/uoh_title_component][vc_column_text css=\"\"]El proyecto estudia los cuidados en perspectiva territorial por medio de un estudio comparativo sobre corresponsabilidad de g\u00e9nero, salud mental y uso del tiempo en la agricultura familiar, especialmente en el caso de mujeres campesinas en 4 regiones del pa\u00eds: Arica y Tarapac\u00e1, Antofagasta, Metropolitana y Araucan\u00eda.[\/vc_column_text][\/vc_column][\/vc_row][\/vc_section][vc_section css=\".vc_custom_1649209804184{background-color: #f6faff !important;}\" el_class=\"p-md-0 pt-md-5\"][vc_row el_class=\"container mx-auto align-items-center p-md-0 pt-5\"][vc_column el_class=\"p-0\"][\/vc_column][\/vc_row][\/vc_section][vc_section css=\".vc_custom_1649210787516{background-color: #f6faff !important;}\" el_class=\"p-md-0 pt-md-5 pb-md-5\"][vc_row el_class=\"container mx-auto align-items-center\"][vc_column][\/vc_column][\/vc_row][\/vc_section]\n                                        <\/div>\n                                    <\/div>\n                                <\/div>\n                            <\/div><div class=\"mt-3\"><i class=\"fas fa-solid fa-user-tag fa-fw me-2\"><\/i><small class=\"text-muted\">Co-Investigador\/a<\/small><\/div><span class=\"caption-field-publish\"><\/span><\/div><\/div><\/div><\/div><\/div><div class=\"  circle--pattern-bottom-large col-sm-12 col-md-12 img-article\"><div class=\"holder-publish col-md-12\" style=\"border-bottom: 1px solid #EFB956\"><div class=\"content-holder h-100 component-border overflow-hidden row m-0 p-4 aling-items-center\"><ul class=\"p-0 list-style-none\"><li class=\"p-0 ms-1\"><i class=\"fa fa-regular fa-calendar fa-fw ms-1\"><\/i>Abril 2026<\/li><\/ul><div class=\"caption col-12 p-0 col-md-12 row m-0 align-items-center\"><div class=\"px-md-1\"><small class=\"badge rounded-pill fw-semibold\" style=\"background-color:#EFB956 !important; color:#FFF\">Adjudicado<\/small><small class=\"ms-2 badge rounded-pill fw-semibold\" style=\"background-color:#F0F1F3 !important; color:#797979\"><i class=\"fa fa-solid fa-lg fa-money-check-dollar fa-fw me-1\"><\/i>Agencia Nacional de Investigaci\u00f3n y Desarrollo - ANID<\/small>\n                            <div class=\"accordion accordion-flush\" id=\"26950\">\n                                <div class=\"accordion-item\">\n                                    <h3 class=\"my-0 small-space pt-2 title-ss text-decoration-none accordion-header\">\n                                        <a role=\"button\" class=\"bg-transparent p-0\" href=\"\">\n                                            <i class=\"fas fa-solid fa-link fa-fw me-2\"><\/i>\n                                            Charting Colon Cancer\u0092s Molecular Axes via an Integrated Multi-Omic Atlas and AI-Driven Histopathology\n                                        <\/a><\/h3>\n                                    <div id=\"collapse-26950\" class=\"accordion-collapse collapse\" data-bs-parent=\"#26950\">\n                                        <div class=\"accordion-body p-0 pt-4 pb-4\">\n                                            [vc_section el_class=\"container mx-auto align-items-center circle--pattern\" css=\".vc_custom_1648956589196{padding-top: 3rem !important;}\"][vc_row el_class=\"pb-5\"][vc_column][vc_wp_custommenu nav_menu=\"6\"][uoh_breadcrumb_component automatic_breadcrumb=\"true\"][uoh_title_component title_dropdown=\"big\" title_decorator=\"true\"]{{title}}[\/uoh_title_component][vc_column_text css=\"\"]Chile is facing one of the steepest increases in Colorectal cancer (CRC) incidence and mortality in the Southern Cone, with\r\nthe greatest surge occurring in adults &#8804; 50 years. Incidence is lowest in the far north and increases toward the\r\nsouth-central regions, mirroring a gradient in Aymara-Mapuche Native-American ancestry, an axis largely absent from the\r\nEuropean reference cohorts that guide modern precision oncology. To fill this gap, we propose a four-year project to create\r\nthe first Chile-specific, multi-omic and histopathological atlas of CRC and to explore ancestry-aware, AI-assisted\r\ndiagnostics.\r\nRationale and Hypothesis.\r\nWe hypothesise that Chilean CRC shows (i) unique, ancestry-driven molecular patterns that differ from European tumors;\r\n(ii) AI models can detect these patterns directly on routine whole-slide images, and (iii) they shape distinct evolutionary\r\npaths in early- versus late-onset disease.\r\nSpecific objectives.\r\nMolecular landscape & heterogeneity: Produce single-gland long-read WGS, methylome, and transcriptome profiles for\r\n100 tumors (30 early-onset, 70 late-onset; &#8805;30\u00d7 coverage, &#8805;50 % purity).\r\nAncestry impact: Phase somatic alterations by local ancestry and contrast their frequencies with European CRC\r\ngenomes (TCGA, PCAWG).\r\nAI-enhanced histopathology: Train and externally validate multi-instance-learning (MIL) models that predict microsatellite\r\ninstability, driver mutations, and whole-genome doubling from matched WSIs, targeting AUC &#8805; 0.80 (pilot: AUC &#8805; 0.85 for\r\nwhole-genome doubling on TCGA WSIs).\r\nEvolutionary trajectories: Multi-region sequence early-onset and late-onset tumors, reconstruct their clonal phylogenies,\r\nand contrast the resulting evolutionary patterns between the two age groups.\r\nTeam capacity & resources. Computational biologist Alex Di Genova (genomics & AI), pathologist Juan Carlos Araya\r\n(digital pathology), and gastro-immunologist Tamara P\u00e9rez-Jeldres (clinical phenotyping) have prospective access to >220\r\nnew CRC resections and >1,800 registry entries each year. A biobank already houses 100 well-annotated tumour\r\nspecimens from hospitals in Santiago and the O\u0092Higgins Region, ready for immediate sequencing and imaging.\r\nAs a team we are delivering important results as (i) the generation of the first telomere-to-telomere Chilean genome,\r\nestablishing a population-specific reference; (ii) sequenced >270 high-coverage whole genomes of chileans individuals (70\r\nhealthy donors, 120 hereditary-breast-cancer cases, 80 primary gallbladder tumors); iii) built the first multi-omic atlas of\r\ngallbladder cancer by integrating our data with Korean (n = 94) and Indian (n = 64) cohorts, uncovering a Chile-enriched\r\nproliferative phenotype; and (iv) developed CRAB-MIL, a weakly supervised deep-learning framework that predicts\r\nwhole-genome doubling from routine H&E slides with an AUC > 0.85 and provides attention maps for interpretability. These\r\naccomplishments demonstrate our ability to generate, integrate, and clinically interpret large-scale genomic and AI\r\ndatasets\u0097capabilities directly transferable to Chilean CRC. International collaborators Ana\u00efs Baudot (Marseille) and Luis\r\nZapata (Institute of Cancer Research, London) further contribute multi-omic network analysis and evolutionary-genomics\r\nexpertise, respectively.\r\nInterdisciplinary workflow. Clinical phenotyping, computational histopathology, PromethION sequencing, and Nextflow\r\nharmonisation feed ancestry-aware genomic analyses; attention-based models are fine-tuned on TCGA and Chilean WSIs;\r\ncomputational, pathology, and gastroenterology teams jointly review outputs to prioritise clinically relevant signals. All\r\nvariant calls, methylomes, expression matrices, AI prediction, and metadata will be released through an open and intuitive\r\nTumorMap portal.\r\nExpected Outcomes and Impact.\r\nThe project will (i) reveal population-specific drivers and mutational processes, (ii) quantify the frequency of clinically\r\nactionable biomarkers originally identified in Europeans, (iii) deliver image-based tools that offer low-cost, molecular\r\nstratification and heterogeneity scoring, and (iv) provide a high-resolution evolutionary framework for EO versus LO CRC.\r\nCollectively, these data will offer the first high-resolution portrait of the Chilean CRC and lay the groundwork for\r\nancestry-aware screening, diagnostic, and treatment strategies.[\/vc_column_text][\/vc_column][\/vc_row][\/vc_section][vc_section css=\".vc_custom_1649209804184{background-color: #f6faff !important;}\" el_class=\"p-md-0 pt-md-5\"][vc_row el_class=\"container mx-auto align-items-center p-md-0 pt-5\"][vc_column el_class=\"p-0\"][\/vc_column][\/vc_row][\/vc_section][vc_section css=\".vc_custom_1649210787516{background-color: #f6faff !important;}\" el_class=\"p-md-0 pt-md-5 pb-md-5\"][vc_row el_class=\"container mx-auto align-items-center\"][vc_column][\/vc_column][\/vc_row][\/vc_section]\n                                        <\/div>\n                                    <\/div>\n                                <\/div>\n                            <\/div><div class=\"mt-3\"><i class=\"fas fa-solid fa-user-tag fa-fw me-2\"><\/i><small class=\"text-muted\">Investigador\/a Responsable<\/small><\/div><span class=\"caption-field-publish\"><\/span><\/div><\/div><\/div><\/div><\/div><div class=\"  circle--pattern-bottom-large col-sm-12 col-md-12 img-article\"><div class=\"holder-publish col-md-12\" style=\"border-bottom: 1px solid #EFB956\"><div class=\"content-holder h-100 component-border overflow-hidden row m-0 p-4 aling-items-center\"><ul class=\"p-0 list-style-none\"><li class=\"p-0 ms-1 me-2\"><i class=\"fa fa-solid fa-id-card-clip fa-fw\"><\/i> 1261473<\/li><li class=\"p-0 ms-1\"><i class=\"fa fa-regular fa-calendar fa-fw ms-1\"><\/i>Abril 2026 - Marzo 2029<\/li><\/ul><div class=\"caption col-12 p-0 col-md-12 row m-0 align-items-center\"><div class=\"px-md-1\"><small class=\"badge rounded-pill fw-semibold\" style=\"background-color:#EFB956 !important; color:#FFF\">Adjudicado<\/small><small class=\"ms-2 badge rounded-pill fw-semibold\" style=\"background-color:#F0F1F3 !important; color:#797979\"><i class=\"fa fa-solid fa-lg fa-money-check-dollar fa-fw me-1\"><\/i>Agencia Nacional de Investigaci\u00f3n y Desarrollo - ANID<\/small>\n                            <div class=\"accordion accordion-flush\" id=\"26188\">\n                                <div class=\"accordion-item\">\n                                    <h3 class=\"my-0 small-space pt-2 title-ss text-decoration-none accordion-header\">\n                                        <a role=\"button\" class=\"bg-transparent p-0\" href=\"\">\n                                            <i class=\"fas fa-solid fa-link fa-fw me-2\"><\/i>\n                                            Geomorphological and ecological dynamics of a deglaciated landscape in the subtropical Andes: The proglacial zone of Universidad Glacier, central Chile (34\u00baS)\n                                        <\/a><\/h3>\n                                    <div id=\"collapse-26188\" class=\"accordion-collapse collapse\" data-bs-parent=\"#26188\">\n                                        <div class=\"accordion-body p-0 pt-4 pb-4\">\n                                            [vc_section el_class=\"container mx-auto align-items-center circle--pattern\" css=\".vc_custom_1648956589196{padding-top: 3rem !important;}\"][vc_row el_class=\"pb-5\"][vc_column][vc_wp_custommenu nav_menu=\"6\"][uoh_breadcrumb_component automatic_breadcrumb=\"true\"][uoh_title_component title_dropdown=\"big\" title_decorator=\"true\"]{{title}}[\/uoh_title_component][vc_column_text css=\"\"].[\/vc_column_text][\/vc_column][\/vc_row][\/vc_section][vc_section css=\".vc_custom_1649209804184{background-color: #f6faff !important;}\" el_class=\"p-md-0 pt-md-5\"][vc_row el_class=\"container mx-auto align-items-center p-md-0 pt-5\"][vc_column el_class=\"p-0\"][\/vc_column][\/vc_row][\/vc_section][vc_section css=\".vc_custom_1649210787516{background-color: #f6faff !important;}\" el_class=\"p-md-0 pt-md-5 pb-md-5\"][vc_row el_class=\"container mx-auto align-items-center\"][vc_column][\/vc_column][\/vc_row][\/vc_section]\n                                        <\/div>\n                                    <\/div>\n                                <\/div>\n                            <\/div><div class=\"mt-3\"><i class=\"fas fa-solid fa-user-tag fa-fw me-2\"><\/i><small class=\"text-muted\">Co-Investigador\/a<\/small><\/div><span class=\"caption-field-publish\"><\/span><\/div><\/div><\/div><\/div><\/div><div class=\"  circle--pattern-bottom-large col-sm-12 col-md-12 img-article\"><div class=\"holder-publish col-md-12\" style=\"border-bottom: 1px solid #EFB956\"><div class=\"content-holder h-100 component-border overflow-hidden row m-0 p-4 aling-items-center\"><ul class=\"p-0 list-style-none\"><li class=\"p-0 ms-1 me-2\"><i class=\"fa fa-solid fa-id-card-clip fa-fw\"><\/i> PYT-2026-186<\/li><li class=\"p-0 ms-1\"><i class=\"fa fa-regular fa-calendar fa-fw ms-1\"><\/i>Abril 2026 - Marzo 2029<\/li><\/ul><div class=\"caption col-12 p-0 col-md-12 row m-0 align-items-center\"><div class=\"px-md-1\"><small class=\"badge rounded-pill fw-semibold\" style=\"background-color:#EFB956 !important; color:#FFF\">Adjudicado<\/small><small class=\"ms-2 badge rounded-pill fw-semibold\" style=\"background-color:#F0F1F3 !important; color:#797979\"><i class=\"fa fa-solid fa-lg fa-money-check-dollar fa-fw me-1\"><\/i>Fundaci\u00f3n para la Innovaci\u00f3n Agraria - FIA<\/small>\n                            <div class=\"accordion accordion-flush\" id=\"26271\">\n                                <div class=\"accordion-item\">\n                                    <h3 class=\"my-0 small-space pt-2 title-ss text-decoration-none accordion-header\">\n                                        <a role=\"button\" class=\"bg-transparent p-0\" href=\"\">\n                                            <i class=\"fas fa-solid fa-link fa-fw me-2\"><\/i>\n                                            Obtenci\u00f3n de ingredientes funcionales desde pulpa de sand\u00eda residual post cosecha para su uso en la industria de alimentos funcionales y en la agricultura\n                                        <\/a><\/h3>\n                                    <div id=\"collapse-26271\" class=\"accordion-collapse collapse\" data-bs-parent=\"#26271\">\n                                        <div class=\"accordion-body p-0 pt-4 pb-4\">\n                                            [vc_section el_class=\"container mx-auto align-items-center circle--pattern\" css=\".vc_custom_1648956589196{padding-top: 3rem !important;}\"][vc_row el_class=\"pb-5\"][vc_column][vc_wp_custommenu nav_menu=\"6\"][uoh_breadcrumb_component automatic_breadcrumb=\"true\"][uoh_title_component title_dropdown=\"big\" title_decorator=\"true\"]{{title}}[\/uoh_title_component][vc_column_text css=\"\"]La producci\u00f3n de semillas de sand\u00eda en Chile es una de las que genera mayores vol\u00famenes (12,5%) y mejores precios (26 MM U$FOB) de\r\nexportaci\u00f3n respecto del total de semillas exportadas. En los \u00faltimos 5 a\u00f1os su exportaci\u00f3n ha aumentado considerablemente ocupando el\r\nsegundo lugar en este mercado. Derivado del procesamiento de los frutos se genera un alto porcentaje de pulpa y c\u00e1scara; residuos no\r\naprovechables como subproducto para otras industrias como cuarta gama y\/o farmac\u00e9utica. El elevado contenido antioxidantes de la sand\u00eda\r\nrepresenta una oportunidad para su extracci\u00f3n y uso en otras industrias. La soluci\u00f3n innovadora permitir\u00e1 reutilizar grandes vol\u00famenes de la\r\npulpa y c\u00e1scara, mitigando su disposici\u00f3n inadecuada y mejorando pr\u00e1cticas agr\u00edcolas y biotecnol\u00f3gicas. El objetivo de la propuesta es\r\ndesarrollar un paquete tecnol\u00f3gico consistente en tres aplicaciones que permiten valorizar los residuos de c\u00e1scara y pulpa de sand\u00eda para la\r\nproducci\u00f3n de nutrac\u00e9uticos, bioenmienda de suelos provenientes de relaves mineros, y sustrato para el crecimiento de microorganismos. El\r\nproyecto busca generar innovaciones que promuevan la transformaci\u00f3n de los residuos agr\u00edcolas, proyectando as\u00ed nuevos negocios para los\r\nproductores hort\u00edcolas en la industria de los alimentos dando valor agregado a los residuos derivados del procesamiento de semillas. Los\r\nresultados esperados de esta iniciativa son: Portafolio de al menos 2 ingredientes funcionales (Licopeno y Citrulina) desarrollados y\r\ncaracterizados; validaci\u00f3n t\u00e9cnica del ingrediente principal (Licopeno o citrulina) con actividad antioxidante; bioenmienda validada en un\r\nentorno operacional (campo), alcanzando el nivel de madurez tecnol\u00f3gica TRL7; an\u00e1lisis de mercado robusto que incluye un plan de\r\nescalamiento t\u00e9cnico de la bioenmienda; medio de cultivo validado en un entorno operacional (empresas), alcanzando el nivel de madurez\r\ntecnol\u00f3gica TRL7; y an\u00e1lisis de mercado robusto que incluye un plan de escalamiento t\u00e9cnico.[\/vc_column_text][\/vc_column][\/vc_row][\/vc_section][vc_section css=\".vc_custom_1649209804184{background-color: #f6faff !important;}\" el_class=\"p-md-0 pt-md-5\"][vc_row el_class=\"container mx-auto align-items-center p-md-0 pt-5\"][vc_column el_class=\"p-0\"][\/vc_column][\/vc_row][\/vc_section][vc_section css=\".vc_custom_1649210787516{background-color: #f6faff !important;}\" el_class=\"p-md-0 pt-md-5 pb-md-5\"][vc_row el_class=\"container mx-auto align-items-center\"][vc_column][\/vc_column][\/vc_row][\/vc_section]\n                                        <\/div>\n                                    <\/div>\n                                <\/div>\n                            <\/div><div class=\"mt-3\"><i class=\"fas fa-solid fa-user-tag fa-fw me-2\"><\/i><small class=\"text-muted\">Responsable Alterno<\/small><\/div><span class=\"caption-field-publish\"><\/span><\/div><\/div><\/div><\/div><\/div><div class=\"  circle--pattern-bottom-large col-sm-12 col-md-12 img-article\"><div class=\"holder-publish col-md-12\" style=\"border-bottom: 1px solid #EFB956\"><div class=\"content-holder h-100 component-border overflow-hidden row m-0 p-4 aling-items-center\"><ul class=\"p-0 list-style-none\"><li class=\"p-0 ms-1\"><i class=\"fa fa-regular fa-calendar fa-fw ms-1\"><\/i>Abril 2026<\/li><\/ul><div class=\"caption col-12 p-0 col-md-12 row m-0 align-items-center\"><div class=\"px-md-1\"><small class=\"badge rounded-pill fw-semibold\" style=\"background-color:#EFB956 !important; color:#FFF\">Adjudicado<\/small><small class=\"ms-2 badge rounded-pill fw-semibold\" style=\"background-color:#F0F1F3 !important; color:#797979\"><i class=\"fa fa-solid fa-lg fa-money-check-dollar fa-fw me-1\"><\/i>Agencia Nacional de Investigaci\u00f3n y Desarrollo - ANID<\/small>\n                            <div class=\"accordion accordion-flush\" id=\"26277\">\n                                <div class=\"accordion-item\">\n                                    <h3 class=\"my-0 small-space pt-2 title-ss text-decoration-none accordion-header\">\n                                        <a role=\"button\" class=\"bg-transparent p-0\" href=\"\">\n                                            <i class=\"fas fa-solid fa-link fa-fw me-2\"><\/i>\n                                            Pressure and shear shock waves on porous matrices: The erosion mechanism underneath water-dripping-on-stone craters\n                                        <\/a><\/h3>\n                                    <div id=\"collapse-26277\" class=\"accordion-collapse collapse\" data-bs-parent=\"#26277\">\n                                        <div class=\"accordion-body p-0 pt-4 pb-4\">\n                                            [vc_section el_class=\"container mx-auto align-items-center circle--pattern\" css=\".vc_custom_1648956589196{padding-top: 3rem !important;}\"][vc_row el_class=\"pb-5\"][vc_column][vc_wp_custommenu nav_menu=\"6\"][uoh_breadcrumb_component automatic_breadcrumb=\"true\"][uoh_title_component title_dropdown=\"big\" title_decorator=\"true\"]{{title}}[\/uoh_title_component][vc_column_text css=\"\"]The phenomenon of a soft liquid drop eroding a hard stone surface over time, immortalized in the ancient proverb \u00abdripping water wears away the stone,\u00bb presents a profound mechanical puzzle. While craters are common imprints of high-energy events, those formed by persistent, low-energy water dripping are exceptional. The impact energy of a single drop is far below the threshold required to plastically deform or fracture the material, yet erosion occurs. This project seeks to answer the fundamental question: How can water erode stone through dripping and create distinctive craters?\r\nWhile recent advancements in drop-impact dynamics have revealed that an impacting drop generates propagating fronts of intense, singular pressure and shear, these theories were developed for ideal, non-porous surfaces and are insufficient to explain the erosion. Our preliminary experimental work\u0097which has successfully reproduced water-dripping craters on gypsum targets while failing to erode non-porous materials\u0097points to a crucial, previously overlooked element: the porous nature of the target material. We discovered that erosion and the formation of a distinct surface microstructure of pores commence only after the substrate becomes fully saturated with water. This key finding suggests that the complex interaction between the impact-induced flow and the internal, liquid-filled pore structure is the primary driver of the erosion mechanism.\r\nThis project will establish the first comprehensive experimental and theoretical framework for slow erosion in porous ma- terials by water dripping. We will investigate three potential and non-exclusive micro-mechanisms. The first is low-Reynolds accumulative erosion, where the impact pressure pumps liquid into the matrix, generating high shear stress along pore walls that slowly abrades material, a process whose rate is expected to be proportional to the wall shear stress. The second is the inter-pore propagation of pressure shocks; because the surface pressure front arrives at adjacent pore openings at slightly different times, large pressure gradients are generated within the saturated matrix, inducing mechanical fatigue and failure of inter-pore walls. The third is cavitation bursts, where the negative-pressure front trailing the initial impact shock\u0097 akin to an explosion\u0092s blast wave\u0097causes the formation and violent collapse of vapor bubbles. These collapses generate localized but highly destructive shock waves, a process potentially detectable via acoustic emissions.\r\nOur methodology integrates a novel, multi-scale experimental approach with robust theoretical modeling. An automated, custom-built setup, featuring a syringe pump for precise drop control and a photo-gate for impact counting and synchroniza- tion, tracks crater evolution over tens of thousands of reproducible impacts. An automated translation stage will move the sample between the impact zone and a characterization chamber for on-the-run 3D shape reconstruction via high-resolution laser profilometry and for mass measurement via an integrated load cell. This will be complemented by a suite of characteriza- tion techniques, including high-speed imaging to capture rare ejecta events, microscopic surface imaging, and advanced bulk imaging (X-ray Micro-Tomography, Scanning Electron Microscopy or Nuclear Magnetic Resonance) to visualize the internal 3D pore network and wear propagation. Experiments will mainly utilize natural materials like gypsum and selenite, as well as custom-fabricated synthetic porous samples (e.g., PDMS). These transparent, engineered samples will allow for direct flow visualization via Particle Image Velocimetry (PIV) to isolate and study specific mechanisms in a controlled environment.\r\nThe theoretical work will couple established models for drop-impact pressure distributions with frameworks for flow in porous media, wall-shear erosion, and wave propagation. The goal is to develop predictive formulae for crater growth rates and their scaling with fluid and material properties, which can be validated against our extensive experimental data. By leveraging the research team\u0092s expertise in drop-impact forces and tackling this 2,500-year-old question, this project will provide novel insights into fluid-solid interactions, wear on porous materials, and landscape evolution. It moves beyond prior studies, which used simplified substrates, to address the central role of porosity in this long-unsolved problem in continuum physics.[\/vc_column_text][\/vc_column][\/vc_row][\/vc_section][vc_section css=\".vc_custom_1649209804184{background-color: #f6faff !important;}\" el_class=\"p-md-0 pt-md-5\"][vc_row el_class=\"container mx-auto align-items-center p-md-0 pt-5\"][vc_column el_class=\"p-0\"][\/vc_column][\/vc_row][\/vc_section][vc_section css=\".vc_custom_1649210787516{background-color: #f6faff !important;}\" el_class=\"p-md-0 pt-md-5 pb-md-5\"][vc_row el_class=\"container mx-auto align-items-center\"][vc_column][\/vc_column][\/vc_row][\/vc_section]\n                                        <\/div>\n                                    <\/div>\n                                <\/div>\n                            <\/div><div class=\"mt-3\"><i class=\"fas fa-solid fa-user-tag fa-fw me-2\"><\/i><small class=\"text-muted\">Co-Investigador\/a<\/small><\/div><span class=\"caption-field-publish\"><\/span><\/div><\/div><\/div><\/div><\/div><div class=\"  circle--pattern-bottom-large col-sm-12 col-md-12 img-article\"><div class=\"holder-publish col-md-12\" style=\"border-bottom: 1px solid #48A2F9\"><div class=\"content-holder h-100 component-border overflow-hidden row m-0 p-4 aling-items-center\"><ul class=\"p-0 list-style-none\"><li class=\"p-0 ms-1\"><i class=\"fa fa-regular fa-calendar fa-fw ms-1\"><\/i>Abril 2026 - Diciembre 2026<\/li><\/ul><div class=\"caption col-12 p-0 col-md-12 row m-0 align-items-center\"><div class=\"px-md-1\"><small class=\"badge rounded-pill fw-semibold\" style=\"background-color:#48A2F9 !important; color:#FFF\">En Ejecuci\u00f3n<\/small><small class=\"ms-2 badge rounded-pill fw-semibold\" style=\"background-color:#F0F1F3 !important; color:#797979\"><i class=\"fa fa-solid fa-lg fa-money-check-dollar fa-fw me-1\"><\/i>Universidad de O'Higgins<\/small>\n                            <div class=\"accordion accordion-flush\" id=\"26380\">\n                                <div class=\"accordion-item\">\n                                    <h3 class=\"my-0 small-space pt-2 title-ss text-decoration-none accordion-header\">\n                                        <a role=\"button\" class=\"bg-transparent p-0\" href=\"\">\n                                            <i class=\"fas fa-solid fa-link fa-fw me-2\"><\/i>\n                                            Paquete tecnol\u00f3gico transferible para el control sustentable de nem\u00e1todos gastrointestinales en ovinos Hidango del secano costero de Cardenal Caro\n                                        <\/a><\/h3>\n                                    <div id=\"collapse-26380\" class=\"accordion-collapse collapse\" data-bs-parent=\"#26380\">\n                                        <div class=\"accordion-body p-0 pt-4 pb-4\">\n                                            [vc_section el_class=\"container mx-auto align-items-center circle--pattern\" css=\".vc_custom_1648956589196{padding-top: 3rem !important;}\"][vc_row el_class=\"pb-5\"][vc_column][vc_wp_custommenu nav_menu=\"6\"][uoh_breadcrumb_component automatic_breadcrumb=\"true\"][uoh_title_component title_dropdown=\"big\" title_decorator=\"true\"]{{title}}[\/uoh_title_component][vc_column_text css=\"\"]En la Provincia de Cardenal Caro, el control de nem\u00e1todos gastrointestinales (NGI) en ovinos se\r\nrealiza principalmente mediante antiparasitarios qu\u00edmicos, con resultados heterog\u00e9neos entre\r\npredios. Esta variabilidad puede responder a una combinaci\u00f3n de factores: composici\u00f3n local de\r\nespecies parasitarias, fallas de dosificaci\u00f3n\/administraci\u00f3n y\/o presencia de resistencia\r\nantihelm\u00edntica. La ausencia de herramientas diagn\u00f3sticas operativas y de criterios\r\nestandarizados de decisi\u00f3n a nivel predial favorece tratamientos repetidos sin evaluaci\u00f3n\r\nobjetiva de eficacia, elevando costos y aumentando la presi\u00f3n de selecci\u00f3n de resistencia, con\r\npotenciales externalidades ambientales asociadas a residuos en heces.\r\nLa propuesta desarrolla y transfiere un paquete tecnol\u00f3gico de bajo costo y alta aplicabilidad\r\npara el secano costero de Cardenal Caro, utilizando ovinos Hidango como poblaci\u00f3n objetivo. El\r\npaquete se estructura en tres componentes integrados: (1) diagn\u00f3stico aplicado y l\u00ednea base\r\nterritorial, basado en muestreo seriado, recuento de huevos (HPG\/EPG) cuando corresponda y\r\nregistro estandarizado de tratamientos, manejo y condici\u00f3n corporal; (2) confirmaci\u00f3n\r\ntaxon\u00f3mica y validaci\u00f3n molecular estrat\u00e9gica (submuestra sentinela) para respaldar la\r\npertinencia territorial de las recomendaciones sin aumentar costos; y (3) transferencia\r\ntecnol\u00f3gica mediante un protocolo operativo (POE), kit de registros y criterios de decisi\u00f3n que\r\npermitan implementar un manejo racional del control parasitario en predios.[\/vc_column_text][\/vc_column][\/vc_row][\/vc_section][vc_section css=\".vc_custom_1649209804184{background-color: #f6faff !important;}\" el_class=\"p-md-0 pt-md-5\"][vc_row el_class=\"container mx-auto align-items-center p-md-0 pt-5\"][vc_column el_class=\"p-0\"][\/vc_column][\/vc_row][\/vc_section][vc_section css=\".vc_custom_1649210787516{background-color: #f6faff !important;}\" el_class=\"p-md-0 pt-md-5 pb-md-5\"][vc_row el_class=\"container mx-auto align-items-center\"][vc_column][\/vc_column][\/vc_row][\/vc_section]\n                                        <\/div>\n                                    <\/div>\n                                <\/div>\n                            <\/div><div class=\"mt-3\"><i class=\"fas fa-solid fa-user-tag fa-fw me-2\"><\/i><small class=\"text-muted\">Investigador\/a Responsable<\/small><\/div><span class=\"caption-field-publish\"><\/span><\/div><\/div><\/div><\/div><\/div><div class=\"  circle--pattern-bottom-large col-sm-12 col-md-12 img-article\"><div class=\"holder-publish col-md-12\" style=\"border-bottom: 1px solid #EFB956\"><div class=\"content-holder h-100 component-border overflow-hidden row m-0 p-4 aling-items-center\"><ul class=\"p-0 list-style-none\"><li class=\"p-0 ms-1\"><i class=\"fa fa-regular fa-calendar fa-fw ms-1\"><\/i>Abril 2026<\/li><\/ul><div class=\"caption col-12 p-0 col-md-12 row m-0 align-items-center\"><div class=\"px-md-1\"><small class=\"badge rounded-pill fw-semibold\" style=\"background-color:#EFB956 !important; color:#FFF\">Adjudicado<\/small><small class=\"ms-2 badge rounded-pill fw-semibold\" style=\"background-color:#F0F1F3 !important; color:#797979\"><i class=\"fa fa-solid fa-lg fa-money-check-dollar fa-fw me-1\"><\/i>Agencia Nacional de Investigaci\u00f3n y Desarrollo - ANID<\/small>\n                            <div class=\"accordion accordion-flush\" id=\"26551\">\n                                <div class=\"accordion-item\">\n                                    <h3 class=\"my-0 small-space pt-2 title-ss text-decoration-none accordion-header\">\n                                        <a role=\"button\" class=\"bg-transparent p-0\" href=\"\">\n                                            <i class=\"fas fa-solid fa-link fa-fw me-2\"><\/i>\n                                            1260236_Language and interculturality: An examination of mediated practices in the conceptualization and implementation of interculturality in the Spanish, Ancestral Languages, and English as a foreign language school subjects\n                                        <\/a><\/h3>\n                                    <div id=\"collapse-26551\" class=\"accordion-collapse collapse\" data-bs-parent=\"#26551\">\n                                        <div class=\"accordion-body p-0 pt-4 pb-4\">\n                                            [vc_section el_class=\"container mx-auto align-items-center circle--pattern\" css=\".vc_custom_1648956589196{padding-top: 3rem !important;}\"][vc_row el_class=\"pb-5\"][vc_column][vc_wp_custommenu nav_menu=\"6\"][uoh_breadcrumb_component automatic_breadcrumb=\"true\"][uoh_title_component title_dropdown=\"big\" title_decorator=\"true\"]{{title}}[\/uoh_title_component][vc_column_text css=\"\"]The rapid increase in immigration and the presence of different Indigenous peoples in the country have resulted in culturally diverse classrooms in Chile. Cultural differences are significant for communication (Otten & Geppert, 2009) and teaching processes (Liddicoat & Scarino, 2013). Hence, intercultural interactions correspond to embodied culture discourses (Carbaugh, 2017; Shi-xu, 2023), which entail the communication practices that take place at institutional levels (i.e., top-down) and language classrooms (i.e., bottom-up). However, some tensions have been identified in these processes, particularly because they seem to maintain cultural and linguistic hierarchies that do not necessarily promote the social mobility or acceptance of minoritized groups (Flores & Rosa, 2015; Unamuno, 2016; Zavala, 2017). Against this backdrop, discursive practices are at the core of how these raciolinguistic hierarchies are maintained, negotiated, and\/or challenged by educational communities. Consequently, the main objective of this research proposal is to examine how language and interculturality are discursively conceptualized and implemented in culturally diverse Chilean schools, specifically within three language subjects: Spanish, Ancestral Languages, and English as a Foreign Language. This objective is articulated through the following research question: How are language and interculturality discursively conceptualized and implemented in culturally diverse Chilean schools across the subjects of Spanish, Ancestral Languages, and English as a Foreign Language? To address this question, the project outlines four specific objectives (SOs): SO1) To examine how interculturality is discursively constructed in educational policies and the national curriculum on language subjects (i.e., Spanish, Ancestral Languages, and English as a Foreign Language); SO2) To assess how language teachers understand and implement intercultural practices in Chile, highlighting areas of convergence and divergence; SO3) To analyze how school communities discursively construct interculturality on their schoolscapes; and SO4) To analyze how language teachers\u0092 actions and decisions address interculturality in the language classroom.\r\nThe proposed research is a mixed-methods study (Creswell & Plano, 2018). First, we will analyze a corpus of institutional pedagogical discourses to examine how interculturality is discursively constructed in educational policies and the national curriculum (SO1). To this end, the data will be examined from a Corpus-Assisted Approach to Discourse Studies (CADS) (Partington et al., 2013) following the guidelines proposed by Jaworska and Kinloch (2018, p. 116) for a thorough and systematic examination of multiple datasets in CADS. The first quantitative stage considers the analysis of frequency, concordance lines, collocations, and keywords. The second qualitative stage is informed by Bacchi's (2012) model, What's the Problem Represented to be? (or WPR) and the Discourse-Historical Approach (Reisigl, 2017; Reisigl & Wodak, 2016). Second, we will conduct a questionnaire to identify how language teachers understand interculturality and intercultural practices in their classrooms (SO2). The sampling considers a disproportionate stratification to enable similar sample sizes for Spanish and EFL teachers, and Traditional Educators, ensuring the representation of Traditional Educators, who are the smallest population (CEM Mineduc, 2024). Third, we will analyze how school communities discursively construct interculturality on their school grounds (SO3) through the examination of schoolscapes (Gorter & Cenoz, 2015). To this end, three schools across three regions will be selected (i.e., Tarapac\u00e1, Metropolitan, and Araucan\u00eda) to ensure geographic representativeness. The data will be analyzed in light of Ledin and Machin\u0092s multimodality framework (2017, 2018, 2019) as it incorporates the materiality of the semiotic signs, the ideologies and beliefs behind the creation of multimodal texts, and the recontextualization of social actors and practices (van Leeuwen, 2008). Finally, we analyze the actions and decisions language teachers take to address interculturality in the language classroom (SO4) through classroom observation (minimum 48 pedagogical hours in total; four hours per language subject) in the same schools. These observations will be analyzed using the synopsis technique (Dolz et al., 2018; Schneuwly & Dolz, 2009), which allows us to both hierarchize central pedagogical sequences and examine teachers' actions and students' reactions in detail. In turn, it enables data reduction and serves as heuristic support for analysis.\r\nExpected results seek to enlighten how educators co-create language and interculturality in culturally diverse schools. It examines how these social actors recontextualize and mediate top-down policies to their daily realities, thus illuminating the negotiation and resemiotization of hegemonic understandings of interculturality in line with the needs of their own communities (bottom-up practices).[\/vc_column_text][\/vc_column][\/vc_row][\/vc_section][vc_section css=\".vc_custom_1649209804184{background-color: #f6faff !important;}\" el_class=\"p-md-0 pt-md-5\"][vc_row el_class=\"container mx-auto align-items-center p-md-0 pt-5\"][vc_column el_class=\"p-0\"][\/vc_column][\/vc_row][\/vc_section][vc_section css=\".vc_custom_1649210787516{background-color: #f6faff !important;}\" el_class=\"p-md-0 pt-md-5 pb-md-5\"][vc_row el_class=\"container mx-auto align-items-center\"][vc_column][\/vc_column][\/vc_row][\/vc_section]\n                                        <\/div>\n                                    <\/div>\n                                <\/div>\n                            <\/div><div class=\"mt-3\"><i class=\"fas fa-solid fa-user-tag fa-fw me-2\"><\/i><small class=\"text-muted\">Investigador\/a Responsable<\/small><\/div><span class=\"caption-field-publish\"><\/span><\/div><\/div><\/div><\/div><\/div><div class=\"  circle--pattern-bottom-large col-sm-12 col-md-12 img-article\"><div class=\"holder-publish col-md-12\" style=\"border-bottom: 1px solid #EFB956\"><div class=\"content-holder h-100 component-border overflow-hidden row m-0 p-4 aling-items-center\"><ul class=\"p-0 list-style-none\"><li class=\"p-0 ms-1 me-2\"><i class=\"fa fa-solid fa-id-card-clip fa-fw\"><\/i> 3261097<\/li><li class=\"p-0 ms-1\"><i class=\"fa fa-regular fa-calendar fa-fw ms-1\"><\/i>Abril 2026<\/li><\/ul><div class=\"caption col-12 p-0 col-md-12 row m-0 align-items-center\"><div class=\"px-md-1\"><small class=\"badge rounded-pill fw-semibold\" style=\"background-color:#EFB956 !important; color:#FFF\">Adjudicado<\/small><small class=\"ms-2 badge rounded-pill fw-semibold\" style=\"background-color:#F0F1F3 !important; color:#797979\"><i class=\"fa fa-solid fa-lg fa-money-check-dollar fa-fw me-1\"><\/i>Agencia Nacional de Investigaci\u00f3n y Desarrollo - ANID<\/small>\n                            <div class=\"accordion accordion-flush\" id=\"26552\">\n                                <div class=\"accordion-item\">\n                                    <h3 class=\"my-0 small-space pt-2 title-ss text-decoration-none accordion-header\">\n                                        <a role=\"button\" class=\"bg-transparent p-0\" href=\"\">\n                                            <i class=\"fas fa-solid fa-link fa-fw me-2\"><\/i>\n                                            Procesos de convivencia intercultural en escuelas secundarias chilenas diversas: un estudio multimodal y decolonial en relaci\u00f3n a los discursos y pr\u00e1cticas escolares sobre la producci\u00f3n de diferencias \u00e9tnicas y migrantes\n                                        <\/a><\/h3>\n                                    <div id=\"collapse-26552\" class=\"accordion-collapse collapse\" data-bs-parent=\"#26552\">\n                                        <div class=\"accordion-body p-0 pt-4 pb-4\">\n                                            [vc_section el_class=\"container mx-auto align-items-center circle--pattern\" css=\".vc_custom_1648956589196{padding-top: 3rem !important;}\"][vc_row el_class=\"pb-5\"][vc_column][vc_wp_custommenu nav_menu=\"6\"][uoh_breadcrumb_component automatic_breadcrumb=\"true\"][uoh_title_component title_dropdown=\"big\" title_decorator=\"true\"]{{title}}[\/uoh_title_component][vc_column_text css=\"\"]Objetivo general: Examinar los procesos de convivencia intercultural y describir los discursos y pr\u00e1cticas escolares sobre la producci\u00f3n de diferencias \u00e9tnicas y migrantes en dos escuelas secundarias chilenas diversas en la Regi\u00f3n de O'Higgins y en la Regi\u00f3n Atacama.[\/vc_column_text][\/vc_column][\/vc_row][\/vc_section][vc_section css=\".vc_custom_1649209804184{background-color: #f6faff !important;}\" el_class=\"p-md-0 pt-md-5\"][vc_row el_class=\"container mx-auto align-items-center p-md-0 pt-5\"][vc_column el_class=\"p-0\"][\/vc_column][\/vc_row][\/vc_section][vc_section css=\".vc_custom_1649210787516{background-color: #f6faff !important;}\" el_class=\"p-md-0 pt-md-5 pb-md-5\"][vc_row el_class=\"container mx-auto align-items-center\"][vc_column][\/vc_column][\/vc_row][\/vc_section]\n                                        <\/div>\n                                    <\/div>\n                                <\/div>\n                            <\/div><div class=\"mt-3\"><i class=\"fas fa-solid fa-user-tag fa-fw me-2\"><\/i><small class=\"text-muted\">Patrocinante<\/small><\/div><span class=\"caption-field-publish\"><\/span><\/div><\/div><\/div><\/div><\/div><div class=\"  circle--pattern-bottom-large col-sm-12 col-md-12 img-article\"><div class=\"holder-publish col-md-12\" style=\"border-bottom: 1px solid #EFB956\"><div class=\"content-holder h-100 component-border overflow-hidden row m-0 p-4 aling-items-center\"><ul class=\"p-0 list-style-none\"><li class=\"p-0 ms-1\"><i class=\"fa fa-regular fa-calendar fa-fw ms-1\"><\/i>Abril 2026 - Marzo 2030<\/li><\/ul><div class=\"caption col-12 p-0 col-md-12 row m-0 align-items-center\"><div class=\"px-md-1\"><small class=\"badge rounded-pill fw-semibold\" style=\"background-color:#EFB956 !important; color:#FFF\">Adjudicado<\/small><small class=\"ms-2 badge rounded-pill fw-semibold\" style=\"background-color:#F0F1F3 !important; color:#797979\"><i class=\"fa fa-solid fa-lg fa-money-check-dollar fa-fw me-1\"><\/i>Agencia Nacional de Investigaci\u00f3n y Desarrollo - ANID<\/small>\n                            <div class=\"accordion accordion-flush\" id=\"26606\">\n                                <div class=\"accordion-item\">\n                                    <h3 class=\"my-0 small-space pt-2 title-ss text-decoration-none accordion-header\">\n                                        <a role=\"button\" class=\"bg-transparent p-0\" href=\"\">\n                                            <i class=\"fas fa-solid fa-link fa-fw me-2\"><\/i>\n                                            Mixed-integer quadratic bilevel optimization algorithms for security and decision-focused learning\n                                        <\/a><\/h3>\n                                    <div id=\"collapse-26606\" class=\"accordion-collapse collapse\" data-bs-parent=\"#26606\">\n                                        <div class=\"accordion-body p-0 pt-4 pb-4\">\n                                            [vc_section el_class=\"container mx-auto align-items-center circle--pattern\" css=\".vc_custom_1648956589196{padding-top: 3rem !important;}\"][vc_row el_class=\"pb-5\"][vc_column][vc_wp_custommenu nav_menu=\"6\"][uoh_breadcrumb_component automatic_breadcrumb=\"true\"][uoh_title_component title_dropdown=\"big\" title_decorator=\"true\"]{{title}}[\/uoh_title_component][vc_column_text css=\"\"]Postulaci\u00f3n a Fondecyt Regular[\/vc_column_text][\/vc_column][\/vc_row][\/vc_section][vc_section css=\".vc_custom_1649209804184{background-color: #f6faff !important;}\" el_class=\"p-md-0 pt-md-5\"][vc_row el_class=\"container mx-auto align-items-center p-md-0 pt-5\"][vc_column el_class=\"p-0\"][\/vc_column][\/vc_row][\/vc_section][vc_section css=\".vc_custom_1649210787516{background-color: #f6faff !important;}\" el_class=\"p-md-0 pt-md-5 pb-md-5\"][vc_row el_class=\"container mx-auto align-items-center\"][vc_column][\/vc_column][\/vc_row][\/vc_section]\n                                        <\/div>\n                                    <\/div>\n                                <\/div>\n                            <\/div><div class=\"mt-3\"><i class=\"fas fa-solid fa-user-tag fa-fw me-2\"><\/i><small class=\"text-muted\">Investigador\/a Responsable<\/small><\/div><span class=\"caption-field-publish\"><\/span><\/div><\/div><\/div><\/div><\/div><div class=\"pagination justify-content-center my-5\"><span aria-current=\"page\" class=\"page-numbers current\">1<\/span>\n<a class=\"page-numbers\" href=\"https:\/\/www.uoh.cl\/investigacion\/wp-json\/wp\/v2\/pages\/348\/\/page\/2\">2<\/a>\n<a class=\"page-numbers\" href=\"https:\/\/www.uoh.cl\/investigacion\/wp-json\/wp\/v2\/pages\/348\/\/page\/3\">3<\/a>\n<span class=\"page-numbers dots\">&hellip;<\/span>\n<a class=\"page-numbers\" href=\"https:\/\/www.uoh.cl\/investigacion\/wp-json\/wp\/v2\/pages\/348\/\/page\/116\">116<\/a>\n<a class=\"next page-numbers\" href=\"https:\/\/www.uoh.cl\/investigacion\/wp-json\/wp\/v2\/pages\/348\/\/page\/2\"><div class=\"icon-pagination-next\"> <?xml version=\"1.0\" ?><svg viewBox=\"0 0 96 96\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><title\/><path d=\"M39.3756,48.0022l30.47-25.39a6.0035,6.0035,0,0,0-7.6878-9.223L26.1563,43.3906a6.0092,6.0092,0,0,0,0,9.2231L62.1578,82.615a6.0035,6.0035,0,0,0,7.6878-9.2231Z\"\/><\/svg> <\/div><\/a><\/div><\/div><\/div><\/div>[\/vc_column][\/vc_row][\/vc_section][vc_section css=&#8221;.vc_custom_1649210787516{background-color: #f6faff !important;}&#8221; 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