
{"id":16,"date":"2022-04-01T19:33:46","date_gmt":"2022-04-01T22:33:46","guid":{"rendered":"https:\/\/www.uoh.cl\/investigacion\/instituto-de-ciencias-sociales\/?page_id=16"},"modified":"2025-06-03T10:17:14","modified_gmt":"2025-06-03T13:17:14","slug":"home","status":"publish","type":"page","link":"https:\/\/www.uoh.cl\/investigacion\/","title":{"rendered":"Investigaci\u00f3n"},"content":{"rendered":"<div class=\"wpb-content-wrapper\"><p>[vc_row el_class=&#8221;mobile-padding-0&#8243;][vc_column el_class=&#8221;mobile-padding-0&#8243;]<div class=\"uoh_slider_featured_component component__featured-slide row mx-auto col-12 m-0 align-items-center position-relative lazyload\" style=\" background:inherit\" data-bg=\"url(https:\/\/www.uoh.cl\/investigacion\/wp-content\/uploads\/sites\/12\/2022\/05\/Foto-Investigacion-1-web-copia-2.jpg)\"><div class=\"caption--degrade\"><svg  xmlns=\"http:\/\/www.w3.org\/2000\/svg\" xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" width=\"1061px\" 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featured-slide title\"  style=\"\"><em>100% de los acad\u00e9micos y acad\u00e9micas con doctorado<\/em>Investigaci\u00f3n<\/h1><\/div><span><\/span><\/div><\/div>[\/vc_column][\/vc_row][vc_section el_id=&#8221;investigacion&#8221; el_class=&#8221;container mx-auto p-md-0 align-items-center&#8221;][vc_row el_class=&#8221;container mx-auto p-0 align-items-center circle&#8211;pattern&#8221;][vc_column css=&#8221;.vc_custom_1648334964471{margin-top: 3rem !important;}&#8221;][vc_wp_custommenu nav_menu=&#8221;5&#8243;][\/vc_column][\/vc_row][vc_row el_class=&#8221;pt-5 pb-5 m-0&#8243;][vc_column el_class=&#8221;m-0&#8243;]<div class=\"uoh_title_component-container\"><h1 class=\"title title--ms d-inline-block title--decorator  big\">Investigaci\u00f3n<\/h1><\/div>[vc_row_inner content_placement=&#8221;middle&#8221; el_class=&#8221;pb-5&#8243;][vc_column_inner width=&#8221;1\/2&#8243; css=&#8221;.vc_custom_1648841686405{margin-right: 100px !important;}&#8221;][vc_column_text css=&#8221;.vc_custom_1649807045976{margin-bottom: 3rem !important;}&#8221;]\u00c9sta busca promover actividades de investigaci\u00f3n y desarrollo al m\u00e1s alto nivel, a cargo de sus acad\u00e9mico\/as e investigadores\/as en el marco de proyectos cient\u00edficos y tecnol\u00f3gicos de alcance regional, nacional e internacional, en concordancia con el Plan de Desarrollo Estrat\u00e9gico de la Universidad.[\/vc_column_text]<div class=\"uoh_link_component pe-4 d-inline-block py-1 simple inline\"><a href=\"https:\/\/www.uoh.cl\/universidad\/vicerrectoria-de-investigacion-y-postgrado\/direccion-de-investigacion\/\"\n                                    class=\"link link--bold component__btn-content\"\n                                    title\"\"\n                                    target=\"\"\n                                    rel=\"\">Direcci\u00f3n de Investigaci\u00f3n<span class=\"icon icon--inline icon--link\"><svg version=\"1.1\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" 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target=\"_blank\"\n                                    rel=\"\">Reglamento de Propiedad Intelectural e Industrial<span class=\"icon icon--inline icon--link\"><svg version=\"1.1\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" x=\"0px\" y=\"0px\" width=\"22px\"height=\"22px\" viewBox=\"0 0 22 22\" style=\"overflow:visible;enable-background:new 0 0 80 64.6;\" xml:space=\"preserve\"><g clip-path=\"url(#acA)\"><path fill-rule=\"evenodd\" d=\"M21.913 11.266a.93.93 0 000-.711c-.022-.056-.063-.097-.091-.144s-.053-.103-.097-.15L12.306.294c-.357-.379-.955-.394-1.334-.038s-.394.955-.038 1.334l7.917 8.374H.927a.95.95 0 00-.908.983.946.946 0 00.908.908h17.924l-8.089 8.552c-.357.379-.341.977.034 1.334s.977.341 1.334-.034l9.594-10.148c.044-.044.063-.1.097-.15.028-.047.069-.088.091-.141z\"\/><\/g><defs><clipPath id=\"acA\"><path fill=\"#fff\" d=\"M0 0h22v22H0z\"\/><\/clipPath><\/defs><\/svg><\/span><\/a><\/div><div class=\"uoh_link_component pe-4 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src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMSIgaGVpZ2h0PSIxIiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjwvc3ZnPg==\" style=\"--smush-placeholder-width: 1920px; --smush-placeholder-aspect-ratio: 1920\/1920;\"><\/div><div class=\"caption uoh-row align-items-center w-100 m-0 h-100\">\n                                     <a  class=\"title text-white caption--title\" href=\"https:\/\/www.uoh.cl\/instituto-ciencias-de-la-salud\"><h3 class=\"title__caption\">Instituto de Ciencias de la Salud<\/h3><\/a>\n                                    <a class=\"link\" href=\"https:\/\/www.uoh.cl\/instituto-ciencias-de-la-salud\">Saber m\u00e1s <span class=\"icon icon--inline icon--link\"><svg version=\"1.1\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" x=\"0px\" y=\"0px\" width=\"22px\"height=\"22px\" viewBox=\"0 0 22 22\" style=\"overflow:visible;enable-background:new 0 0 80 64.6;\" xml:space=\"preserve\"><g clip-path=\"url(#acA)\"><path fill-rule=\"evenodd\" d=\"M21.913 11.266a.93.93 0 000-.711c-.022-.056-.063-.097-.091-.144s-.053-.103-.097-.15L12.306.294c-.357-.379-.955-.394-1.334-.038s-.394.955-.038 1.334l7.917 8.374H.927a.95.95 0 00-.908.983.946.946 0 00.908.908h17.924l-8.089 8.552c-.357.379-.341.977.034 1.334s.977.341 1.334-.034l9.594-10.148c.044-.044.063-.1.097-.15.028-.047.069-.088.091-.141z\"\/><\/g><defs><clipPath id=\"acA\"><path fill=\"#fff\" d=\"M0 0h22v22H0z\"\/><\/clipPath><\/defs><\/svg><\/span><\/a><\/div><\/div><\/div><\/div>[\/vc_column][\/vc_row][vc_row el_class=&#8221;pb-5 m-0&#8243;][vc_column width=&#8221;1\/4&#8243;]<div class=\"col-12>\n                            <img-article p-md-1\">\n                            <div class=\"holder featured__block component-border\"><div class=\"content-holder component-border overflow-hidden row m-0  aling-items-center\"><div class=\"p-0 col-12 w-100 h-100\"><img decoding=\"async\" class=\"w-100 h-100 lazyload\" data-src=\"https:\/\/www.uoh.cl\/investigacion\/wp-content\/uploads\/sites\/12\/2022\/05\/Foto-Inst-Sociales-web-copia-4.jpg\" alt=\"Instituto de Ciencias Sociales\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMSIgaGVpZ2h0PSIxIiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjwvc3ZnPg==\" style=\"--smush-placeholder-width: 1920px; --smush-placeholder-aspect-ratio: 1920\/1920;\"><\/div><div class=\"caption uoh-row align-items-center w-100 m-0 h-100\">\n                                     <a  class=\"title text-white caption--title\" href=\"https:\/\/www.uoh.cl\/instituto-de-ciencias-sociales\"><h3 class=\"title__caption\">Instituto de Ciencias Sociales<\/h3><\/a>\n                                    <a class=\"link\" href=\"https:\/\/www.uoh.cl\/instituto-de-ciencias-sociales\">Saber m\u00e1s <span class=\"icon icon--inline icon--link\"><svg version=\"1.1\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" x=\"0px\" y=\"0px\" width=\"22px\"height=\"22px\" viewBox=\"0 0 22 22\" style=\"overflow:visible;enable-background:new 0 0 80 64.6;\" xml:space=\"preserve\"><g clip-path=\"url(#acA)\"><path fill-rule=\"evenodd\" d=\"M21.913 11.266a.93.93 0 000-.711c-.022-.056-.063-.097-.091-.144s-.053-.103-.097-.15L12.306.294c-.357-.379-.955-.394-1.334-.038s-.394.955-.038 1.334l7.917 8.374H.927a.95.95 0 00-.908.983.946.946 0 00.908.908h17.924l-8.089 8.552c-.357.379-.341.977.034 1.334s.977.341 1.334-.034l9.594-10.148c.044-.044.063-.1.097-.15.028-.047.069-.088.091-.141z\"\/><\/g><defs><clipPath id=\"acA\"><path fill=\"#fff\" d=\"M0 0h22v22H0z\"\/><\/clipPath><\/defs><\/svg><\/span><\/a><\/div><\/div><\/div><\/div>[\/vc_column][vc_column width=&#8221;1\/4&#8243;]<div class=\"col-12>\n                            <img-article p-md-1\">\n                            <div class=\"holder featured__block component-border\"><div class=\"content-holder component-border overflow-hidden row m-0  aling-items-center\"><div class=\"p-0 col-12 w-100 h-100\"><img decoding=\"async\" class=\"w-100 h-100 lazyload\" data-src=\"https:\/\/www.uoh.cl\/investigacion\/wp-content\/uploads\/sites\/12\/2022\/05\/Foto-IEA-web-copia-4.jpg\" alt=\"Instituto de Altos Estudios Audiovisuales\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMSIgaGVpZ2h0PSIxIiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjwvc3ZnPg==\" style=\"--smush-placeholder-width: 1920px; --smush-placeholder-aspect-ratio: 1920\/1920;\"><\/div><div class=\"caption uoh-row align-items-center w-100 m-0 h-100\">\n                                     <a  class=\"title text-white caption--title\" href=\"https:\/\/www.uoh.cl\/instituto-de-altos-estudios-audiovisuales\"><h3 class=\"title__caption\">Instituto de Altos Estudios Audiovisuales<\/h3><\/a>\n                                    <a class=\"link\" href=\"https:\/\/www.uoh.cl\/instituto-de-altos-estudios-audiovisuales\">Saber m\u00e1s <span class=\"icon icon--inline icon--link\"><svg version=\"1.1\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" x=\"0px\" y=\"0px\" width=\"22px\"height=\"22px\" viewBox=\"0 0 22 22\" style=\"overflow:visible;enable-background:new 0 0 80 64.6;\" xml:space=\"preserve\"><g clip-path=\"url(#acA)\"><path fill-rule=\"evenodd\" d=\"M21.913 11.266a.93.93 0 000-.711c-.022-.056-.063-.097-.091-.144s-.053-.103-.097-.15L12.306.294c-.357-.379-.955-.394-1.334-.038s-.394.955-.038 1.334l7.917 8.374H.927a.95.95 0 00-.908.983.946.946 0 00.908.908h17.924l-8.089 8.552c-.357.379-.341.977.034 1.334s.977.341 1.334-.034l9.594-10.148c.044-.044.063-.1.097-.15.028-.047.069-.088.091-.141z\"\/><\/g><defs><clipPath id=\"acA\"><path fill=\"#fff\" d=\"M0 0h22v22H0z\"\/><\/clipPath><\/defs><\/svg><\/span><\/a><\/div><\/div><\/div><\/div>[\/vc_column][vc_column width=&#8221;1\/4&#8243;][\/vc_column][vc_column width=&#8221;1\/4&#8243;][\/vc_column][\/vc_row][\/vc_section][vc_section el_id=&#8221;cifras&#8221; css=&#8221;.vc_custom_1680727183212{margin-bottom: 60px !important;}&#8221; el_class=&#8221;container mx-auto p-md-0 align-items-center pb-5&#8243;][vc_row el_class=&#8221;m-0&#8243;][vc_column]<div class=\"uoh_title_component-container\"><h2 class=\"title title--ms d-inline-block title--decorator  medium\">Convocatorias<\/h2><\/div>[\/vc_column][\/vc_row][vc_row el_class=&#8221;container mx-auto p-md-0 align-items-center pb-5&#8243;][vc_column width=&#8221;1\/2&#8243;]<div class=\"col-12>\n                            <img-article p-md-1\">\n                            <div class=\"holder featured__block component-border\"><div class=\"content-holder component-border overflow-hidden row m-0  aling-items-center\"><div class=\"p-0 col-12 w-100 h-100\"><img decoding=\"async\" class=\"w-100 h-100 lazyload\" data-src=\"https:\/\/www.uoh.cl\/investigacion\/wp-content\/uploads\/sites\/12\/2023\/04\/Investigacion-600x600.png\" alt=\"Externas\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMSIgaGVpZ2h0PSIxIiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjwvc3ZnPg==\" style=\"--smush-placeholder-width: 600px; --smush-placeholder-aspect-ratio: 600\/600;\"><\/div><div class=\"caption uoh-row align-items-center w-100 m-0 h-100\">\n                                     <a  class=\"title text-white caption--title\" href=\"https:\/\/www.uoh.cl\/investigacion\/convocatorias-externas\/\"><h3 class=\"title__caption\">Externas<\/h3><\/a>\n                                    <a class=\"link\" href=\"https:\/\/www.uoh.cl\/investigacion\/convocatorias-externas\/\">Saber m\u00e1s <span class=\"icon icon--inline icon--link\"><svg version=\"1.1\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" x=\"0px\" y=\"0px\" width=\"22px\"height=\"22px\" viewBox=\"0 0 22 22\" style=\"overflow:visible;enable-background:new 0 0 80 64.6;\" xml:space=\"preserve\"><g clip-path=\"url(#acA)\"><path fill-rule=\"evenodd\" d=\"M21.913 11.266a.93.93 0 000-.711c-.022-.056-.063-.097-.091-.144s-.053-.103-.097-.15L12.306.294c-.357-.379-.955-.394-1.334-.038s-.394.955-.038 1.334l7.917 8.374H.927a.95.95 0 00-.908.983.946.946 0 00.908.908h17.924l-8.089 8.552c-.357.379-.341.977.034 1.334s.977.341 1.334-.034l9.594-10.148c.044-.044.063-.1.097-.15.028-.047.069-.088.091-.141z\"\/><\/g><defs><clipPath id=\"acA\"><path fill=\"#fff\" d=\"M0 0h22v22H0z\"\/><\/clipPath><\/defs><\/svg><\/span><\/a><\/div><\/div><\/div><\/div>[\/vc_column][vc_column width=&#8221;1\/2&#8243;]<div class=\"col-12>\n                            <img-article p-md-1\">\n                            <div class=\"holder featured__block component-border\"><div class=\"content-holder component-border overflow-hidden row m-0  aling-items-center\"><div class=\"p-0 col-12 w-100 h-100\"><img decoding=\"async\" class=\"w-100 h-100 lazyload\" data-src=\"https:\/\/www.uoh.cl\/investigacion\/wp-content\/uploads\/sites\/12\/2023\/04\/Investigacion-1-600x600.png\" alt=\"Internas\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMSIgaGVpZ2h0PSIxIiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjwvc3ZnPg==\" style=\"--smush-placeholder-width: 600px; --smush-placeholder-aspect-ratio: 600\/600;\"><\/div><div class=\"caption uoh-row align-items-center w-100 m-0 h-100\">\n                                     <a  class=\"title text-white caption--title\" href=\"https:\/\/www.uoh.cl\/investigacion\/convocatorias-internas\/\"><h3 class=\"title__caption\">Internas<\/h3><\/a>\n                                    <a class=\"link\" href=\"https:\/\/www.uoh.cl\/investigacion\/convocatorias-internas\/\">Saber m\u00e1s <span class=\"icon icon--inline icon--link\"><svg version=\"1.1\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" x=\"0px\" y=\"0px\" width=\"22px\"height=\"22px\" viewBox=\"0 0 22 22\" style=\"overflow:visible;enable-background:new 0 0 80 64.6;\" xml:space=\"preserve\"><g clip-path=\"url(#acA)\"><path fill-rule=\"evenodd\" d=\"M21.913 11.266a.93.93 0 000-.711c-.022-.056-.063-.097-.091-.144s-.053-.103-.097-.15L12.306.294c-.357-.379-.955-.394-1.334-.038s-.394.955-.038 1.334l7.917 8.374H.927a.95.95 0 00-.908.983.946.946 0 00.908.908h17.924l-8.089 8.552c-.357.379-.341.977.034 1.334s.977.341 1.334-.034l9.594-10.148c.044-.044.063-.1.097-.15.028-.047.069-.088.091-.141z\"\/><\/g><defs><clipPath id=\"acA\"><path fill=\"#fff\" d=\"M0 0h22v22H0z\"\/><\/clipPath><\/defs><\/svg><\/span><\/a><\/div><\/div><\/div><\/div>[\/vc_column][\/vc_row][\/vc_section][vc_section css=&#8221;.vc_custom_1649812420360{margin-bottom: 60px !important;background-color: #f6faff !important;}&#8221;][vc_row el_class=&#8221;container mx-auto p-md-0 align-items-center pb-5&#8243;][vc_column]<div class=\"uoh_title_component-container\"><h2 class=\"title title--ms d-inline-block medium\">Cifras<\/h2><\/div>[vc_row_inner el_class=&#8221;pt-4 pb-5&#8243;][vc_column_inner width=&#8221;1\/4&#8243;]<div class=\"box-container__info circle--pattern\" style=\"border-top: 4px solid #42a0f8\"><figure ><img decoding=\"async\" data-src=\"https:\/\/www.uoh.cl\/investigacion\/wp-content\/uploads\/sites\/12\/2022\/04\/projects-1.jpg\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMSIgaGVpZ2h0PSIxIiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjwvc3ZnPg==\" class=\"lazyload\" style=\"--smush-placeholder-width: 128px; --smush-placeholder-aspect-ratio: 128\/128;\" \/><figcaption class=\"uoh_row m-0 align-items-center\">\n                        <div class=\"\"><h5 class=\"title__caption mb-3\">208<\/h5><div> <p>Proyectos de investigaci\u00f3n como responsables o co-investigadoras\/es entre 2017 y 2021 (66 Fondecyt)<\/p><\/div><\/div> <\/figcaption><\/figure><\/div>[\/vc_column_inner][vc_column_inner width=&#8221;1\/4&#8243;]<div class=\"box-container__info circle--pattern\" style=\"border-top: 4px solid #42a0f8\"><figure ><img decoding=\"async\" data-src=\"https:\/\/www.uoh.cl\/investigacion\/wp-content\/uploads\/sites\/12\/2022\/04\/publish.jpg\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMSIgaGVpZ2h0PSIxIiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjwvc3ZnPg==\" class=\"lazyload\" style=\"--smush-placeholder-width: 128px; --smush-placeholder-aspect-ratio: 128\/128;\" \/><figcaption class=\"uoh_row m-0 align-items-center\">\n                        <div class=\"\"><h5 class=\"title__caption mb-3\">311<\/h5><div> <p>Publicaciones cient\u00edficas entre 2017 y 2021 (266 en Scopus)<\/p><\/div><\/div> <\/figcaption><\/figure><\/div>[\/vc_column_inner][vc_column_inner width=&#8221;1\/4&#8243;]<div class=\"box-container__info circle--pattern\" style=\"border-top: 4px solid #42a0f8\"><figure ><img decoding=\"async\" data-src=\"https:\/\/www.uoh.cl\/investigacion\/wp-content\/uploads\/sites\/12\/2022\/04\/institutos.jpg\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMSIgaGVpZ2h0PSIxIiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjwvc3ZnPg==\" class=\"lazyload\" style=\"--smush-placeholder-width: 128px; --smush-placeholder-aspect-ratio: 128\/128;\" \/><figcaption class=\"uoh_row m-0 align-items-center\">\n                        <div class=\"\"><h5 class=\"title__caption mb-3\">6<\/h5><div> <p>Institutos de investigaci\u00f3n interdisciplinaria en 2021<\/p><\/div><\/div> <\/figcaption><\/figure><\/div>[\/vc_column_inner][vc_column_inner width=&#8221;1\/4&#8243;]<div class=\"box-container__info circle--pattern\" style=\"border-top: 4px solid #42a0f8\"><figure ><img decoding=\"async\" data-src=\"https:\/\/www.uoh.cl\/investigacion\/wp-content\/uploads\/sites\/12\/2022\/04\/gorra.jpg\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMSIgaGVpZ2h0PSIxIiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjwvc3ZnPg==\" class=\"lazyload\" style=\"--smush-placeholder-width: 128px; --smush-placeholder-aspect-ratio: 128\/128;\" \/><figcaption class=\"uoh_row m-0 align-items-center\">\n                        <div class=\"\"><h5 class=\"title__caption mb-3\">100%<\/h5><div> <p>De acad\u00e9micas\/os con grado de Doctor en 2021<\/p><\/div><\/div> <\/figcaption><\/figure><\/div>[\/vc_column_inner][\/vc_row_inner][\/vc_column][\/vc_row][\/vc_section][vc_section el_id=&#8221;proyectos&#8221; el_class=&#8221;container mx-auto p-0 align-items-center pb-5&#8243;][\/vc_section][vc_section el_class=&#8221;container mx-auto p-0 align-items-center pb-5&#8243;][vc_row el_class=&#8221;pb-5&#8243;][vc_column]<link rel=\"stylesheet\" id=\"font-awesome-css\" href=\"https:\/\/cdnjs.cloudflare.com\/ajax\/libs\/font-awesome\/6.5.1\/css\/all.min.css\" type=\"text\/css\" media=\"all\"><div class=\"row m-0 p-0\"><div class=\"col-12 col-md-9 pt-5 pt-md-0 px-md-0 \"><h2 class=\"title title--decorator title--ms d-inline-block\">Proyectos<\/h2><\/div><div class=\"swipper-buttons col-12 col-md-3 row m-0  justify-content-center justify-content-md-end pe-0 \">\n                    <div class=\"swiper-button-prev-publish-59 swiper-button-prev-component\"><span class=\"icon icon--inline icon--slide icon--slide-left\"><svg version=\"1.1\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" x=\"0px\" y=\"0px\" width=\"22px\"height=\"22px\" viewBox=\"0 0 22 22\" style=\"overflow:visible;enable-background:new 0 0 80 64.6;\" xml:space=\"preserve\"><g clip-path=\"url(#acA)\"><path fill-rule=\"evenodd\" d=\"M21.913 11.266a.93.93 0 000-.711c-.022-.056-.063-.097-.091-.144s-.053-.103-.097-.15L12.306.294c-.357-.379-.955-.394-1.334-.038s-.394.955-.038 1.334l7.917 8.374H.927a.95.95 0 00-.908.983.946.946 0 00.908.908h17.924l-8.089 8.552c-.357.379-.341.977.034 1.334s.977.341 1.334-.034l9.594-10.148c.044-.044.063-.1.097-.15.028-.047.069-.088.091-.141z\"\/><\/g><defs><clipPath id=\"acA\"><path fill=\"#fff\" d=\"M0 0h22v22H0z\"\/><\/clipPath><\/defs><\/svg><\/span><\/div>\n                    <div class=\"swiper-pagination-component-publish-59\"><\/div>\n                    <div class=\"swiper-button-next-publish-59 swiper-button-prev-component\"><span class=\"icon icon--inline icon--slide \"><svg version=\"1.1\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" x=\"0px\" y=\"0px\" width=\"22px\"height=\"22px\" viewBox=\"0 0 22 22\" style=\"overflow:visible;enable-background:new 0 0 80 64.6;\" xml:space=\"preserve\"><g clip-path=\"url(#acA)\"><path fill-rule=\"evenodd\" d=\"M21.913 11.266a.93.93 0 000-.711c-.022-.056-.063-.097-.091-.144s-.053-.103-.097-.15L12.306.294c-.357-.379-.955-.394-1.334-.038s-.394.955-.038 1.334l7.917 8.374H.927a.95.95 0 00-.908.983.946.946 0 00.908.908h17.924l-8.089 8.552c-.357.379-.341.977.034 1.334s.977.341 1.334-.034l9.594-10.148c.044-.044.063-.1.097-.15.028-.047.069-.088.091-.141z\"\/><\/g><defs><clipPath id=\"acA\"><path fill=\"#fff\" d=\"M0 0h22v22H0z\"\/><\/clipPath><\/defs><\/svg><\/span><\/div> <\/div><\/div><div class=\"content-holder row m-0 p-0 aling-items-center pt-5 pb-5 \"><div class=\"row swiper large--swipper-content p-0 publish-59\"><div class=\"swiper-wrapper\"><div class=\" swiper-slide circle--pattern-bottom-large col-sm-12 col-md-6 img-article\"><div class=\"holder-publish \" style=\"border-bottom: 1px solid #48A2F9\"><div class=\"content-holder h-100 component-border overflow-hidden row m-0 p-4 aling-items-center\"><ul class=\"p-0 list-style-none\"><li class=\"p-0 ms-1\"><i class=\"fa fa-regular fa-calendar fa-fw ms-1\"><\/i>Septiembre 2024<\/li><\/ul><div class=\"caption col-12 p-0 col-md-12 row m-0 align-items-center\"><div class=\"px-md-1\"><small class=\"badge rounded-pill fw-semibold\" style=\"background-color:#48A2F9 !important; color:#FFF\">En Ejecuci\u00f3n<\/small><small class=\"ms-2 badge rounded-pill fw-semibold\" style=\"background-color:#F0F1F3 !important; color:#797979\"><i class=\"fa fa-solid fa-lg fa-money-check-dollar fa-fw me-1\"><\/i>International Centre for Antimicrobial Resistance Solutions (ICARS)<\/small>\n                            <div class=\"accordion accordion-flush\" id=\"36993\">\n                                <div class=\"accordion-item\">\n                                    <h3 class=\"my-0 small-space pt-2 title-ss text-decoration-none accordion-header\">\n                                        <a role=\"button\" class=\"bg-transparent p-0\" href=\"\">\n                                            <i class=\"fas fa-solid fa-link fa-fw me-2\"><\/i>\n                                            Surveillance, alert, and response system (SVAR) for the use of antimicrobials in Chilean salmon farming\n                                        <\/a><\/h3>\n                                    <div id=\"collapse-36993\" class=\"accordion-collapse collapse\" data-bs-parent=\"#36993\">\n                                        <div class=\"accordion-body p-0 pt-4 pb-4\">\n                                            [vc_section el_class=\"container mx-auto align-items-center circle--pattern\" css=\".vc_custom_1648956589196{padding-top: 3rem !important;}\"][vc_row el_class=\"pb-5\"][vc_column][vc_wp_custommenu nav_menu=\"6\"][uoh_breadcrumb_component automatic_breadcrumb=\"true\"][uoh_title_component title_dropdown=\"big\" title_decorator=\"true\"]{{title}}[\/uoh_title_component][vc_column_text css=\"\"]The use of antimicrobials (AMU) in the salmon farming industry in Chile is concentrated in the sea fattening phase of the production cycle. In 2022, 91% of the AMU in fattening farms was for treatment of Piscirickettsia salmonis (Sernapesca, 2023), the main disease-causing pathogen affecting farmed salmon in Chile (Rozas and Enriquez, 2014).\r\n\r\nTo control P. salmonis, a series of preventive strategies have been adopted. Nevertheless, the incidence of P. salmonis remains high; resulting in high mortality rates (Jakob et al., 2014) and extensive AMU. The use of antimicrobials is exacerbated by current management practices in salmon farms as well as a lack of standardization in treatment guidelines and practices between veterinarians and companies (e.g. treatment of all or selected cages, dosage, etc.), but also because of limited consolidation, communication and use of available AMU data.\r\n\r\nThe aim of this project is to reduce antimicrobial consumption in salmon farming in Los Lagos and Aysen regions where P. salmonis is a challenge and improve science-based governance of AMU in the salmon farming sector through a surveillance, alert and response system (SVARS). The project will be implemented in two phases. Phase one will focus on increasing the knowledge of AMU drivers by developing a catalog of practices and factors that impact the use of antimicrobials and conduct a cost-effectiveness analysis to assess the more cost efficient alternative methods to AMU practices. The catalog will be compiled in a format that can be used to implement improvements on high AMU farms. Different AMU metrics will be reviewed and selected to differentiate farms with low, medium and high AMU. In addition, the legislative requirements to develop and sustain a surveillance, alert and response system (SVARS) to reduce AMU in Chilean salmon farming will be reviewed. Finally, the infrastructural and operational requirements for the platform will be assessed and the design of the platform will be completed, integrating geospatial and health information.\r\n\r\nIn phase two, the SVARS will categorize the farms based on their AMU levels. The high use farms will be recruited to a Randomized Controlled Trial where intervention farms will implement practices and methods from the catalog created in phase one to reduce AMU. The outcomes and the effectiveness of the SVARS will be quantitatively and qualitatively assessed. Finally, results and outcomes of establishing and implementing the SVARS will be shared with relevant stakeholders in Chile, to low-and middle-income countries in the region and beyond, e.g. through workshops and education training programs in order to disseminate the results.[\/vc_column_text][\/vc_column][\/vc_row][\/vc_section][vc_section css=\".vc_custom_1649209804184{background-color: #f6faff !important;}\" el_class=\"p-md-0 pt-md-5\"][vc_row el_class=\"container mx-auto align-items-center p-md-0 pt-5\"][vc_column el_class=\"p-0\"][\/vc_column][\/vc_row][\/vc_section][vc_section css=\".vc_custom_1649210787516{background-color: #f6faff !important;}\" el_class=\"p-md-0 pt-md-5 pb-md-5\"][vc_row el_class=\"container mx-auto align-items-center\"][vc_column][\/vc_column][\/vc_row][\/vc_section]\n                                        <\/div>\n                                    <\/div>\n                                <\/div>\n                            <\/div><div class=\"mt-3\"><i class=\"fas fa-solid fa-user-tag fa-fw me-2\"><\/i><small class=\"text-muted\">Investigador\/a Responsable<\/small><\/div><span class=\"caption-field-publish\"><\/span><\/div><\/div><\/div><\/div><\/div><div class=\" swiper-slide circle--pattern-bottom-large col-sm-12 col-md-6 img-article\"><div class=\"holder-publish \" style=\"border-bottom: 1px solid #48A2F9\"><div class=\"content-holder h-100 component-border overflow-hidden row m-0 p-4 aling-items-center\"><ul class=\"p-0 list-style-none\"><li class=\"p-0 ms-1 me-2\"><i class=\"fa fa-solid fa-id-card-clip fa-fw\"><\/i> 24I10188<\/li><li class=\"p-0 ms-1\"><i class=\"fa fa-regular fa-calendar fa-fw ms-1\"><\/i>Junio 2024 - Junio 2026<\/li><\/ul><div class=\"caption col-12 p-0 col-md-12 row m-0 align-items-center\"><div class=\"px-md-1\"><small class=\"badge rounded-pill fw-semibold\" style=\"background-color:#48A2F9 !important; color:#FFF\">En Ejecuci\u00f3n<\/small><small class=\"ms-2 badge rounded-pill fw-semibold\" style=\"background-color:#F0F1F3 !important; color:#797979\"><i class=\"fa fa-solid fa-lg fa-money-check-dollar fa-fw me-1\"><\/i>Agencia Nacional de Investigaci\u00f3n y Desarrollo - ANID<\/small>\n                            <div class=\"accordion accordion-flush\" id=\"36995\">\n                                <div class=\"accordion-item\">\n                                    <h3 class=\"my-0 small-space pt-2 title-ss text-decoration-none accordion-header\">\n                                        <a role=\"button\" class=\"bg-transparent p-0\" href=\"\">\n                                            <i class=\"fas fa-solid fa-link fa-fw me-2\"><\/i>\n                                            Herramienta molecular para el monitoreo de la sensibilidad farmacol\u00f3gica de productos antiparasitarios contra el piojo de mar en la industria salmonera\n                                        <\/a><\/h3>\n                                    <div id=\"collapse-36995\" class=\"accordion-collapse collapse\" data-bs-parent=\"#36995\">\n                                        <div class=\"accordion-body p-0 pt-4 pb-4\">\n                                            [vc_section el_class=\"container mx-auto align-items-center circle--pattern\" css=\".vc_custom_1648956589196{padding-top: 3rem !important;}\"][vc_row el_class=\"pb-5\"][vc_column][vc_wp_custommenu nav_menu=\"6\"][uoh_breadcrumb_component automatic_breadcrumb=\"true\"][uoh_title_component title_dropdown=\"big\" title_decorator=\"true\"]{{title}}[\/uoh_title_component][vc_column_text css=\"\"]Objetivo General\r\nDesarrollar un kit de qPCR que permita evaluar con precisi\u00f3n la sensibilidad farmacol\u00f3gica de C.\r\nrogercresseyi a tratamientos como inhibidores de quitina mediante asociaci\u00f3n estad\u00edstica entre\r\nfrecuencia de marcadores gen\u00f3micos y eficacia de tratamientos en campo.\r\n\r\nObjetivos Espec\u00edficos\r\n1. Validar estad\u00edsticamente la relaci\u00f3n entre las variantes gen\u00f3micas detectadas por el kit de\r\nqPCR y la resistencia a tratamientos con inhibidores de quitina.\r\n2. Establecer un protocolo de buenas pr\u00e1cticas de laboratorio para la correcta aplicaci\u00f3n del\r\nkit de qPCR.\r\n3. Implementar capacitaciones para laboratorios y culminar con la certificaci\u00f3n de aquellos\r\naptos para aplicar la t\u00e9cnica con eficacia.[\/vc_column_text][\/vc_column][\/vc_row][\/vc_section][vc_section css=\".vc_custom_1649209804184{background-color: #f6faff !important;}\" el_class=\"p-md-0 pt-md-5\"][vc_row el_class=\"container mx-auto align-items-center p-md-0 pt-5\"][vc_column el_class=\"p-0\"][\/vc_column][\/vc_row][\/vc_section][vc_section css=\".vc_custom_1649210787516{background-color: #f6faff !important;}\" el_class=\"p-md-0 pt-md-5 pb-md-5\"][vc_row el_class=\"container mx-auto align-items-center\"][vc_column][\/vc_column][\/vc_row][\/vc_section]\n                                        <\/div>\n                                    <\/div>\n                                <\/div>\n                            <\/div><div class=\"mt-3\"><i class=\"fas fa-solid fa-user-tag fa-fw me-2\"><\/i><small class=\"text-muted\">Co-Investigador\/a<\/small><\/div><span class=\"caption-field-publish\"><\/span><\/div><\/div><\/div><\/div><\/div><div class=\" swiper-slide circle--pattern-bottom-large col-sm-12 col-md-6 img-article\"><div class=\"holder-publish \" style=\"border-bottom: 1px solid #EFB956\"><div class=\"content-holder h-100 component-border overflow-hidden row m-0 p-4 aling-items-center\"><ul class=\"p-0 list-style-none\"><li class=\"p-0 ms-1\"><i class=\"fa fa-regular fa-calendar fa-fw ms-1\"><\/i>Abril 2024 - Marzo 2027<\/li><\/ul><div class=\"caption col-12 p-0 col-md-12 row m-0 align-items-center\"><div class=\"px-md-1\"><small class=\"badge rounded-pill fw-semibold\" style=\"background-color:#EFB956 !important; color:#FFF\">Adjudicado<\/small><small class=\"ms-2 badge rounded-pill fw-semibold\" style=\"background-color:#F0F1F3 !important; color:#797979\"><i class=\"fa fa-solid fa-lg fa-money-check-dollar fa-fw me-1\"><\/i>Agencia Nacional de Investigaci\u00f3n y Desarrollo - ANID<\/small>\n                            <div class=\"accordion accordion-flush\" id=\"37017\">\n                                <div class=\"accordion-item\">\n                                    <h3 class=\"my-0 small-space pt-2 title-ss text-decoration-none accordion-header\">\n                                        <a role=\"button\" class=\"bg-transparent p-0\" href=\"\">\n                                            <i class=\"fas fa-solid fa-link fa-fw me-2\"><\/i>\n                                            A Biopsychosocial Approach for Frailty Intervention: Uncovering a Circulating microRNA Biomarker Panel Using an Omics-Based Machine Learning Approach\n                                        <\/a><\/h3>\n                                    <div id=\"collapse-37017\" class=\"accordion-collapse collapse\" data-bs-parent=\"#37017\">\n                                        <div class=\"accordion-body p-0 pt-4 pb-4\">\n                                            [vc_section el_class=\"container mx-auto align-items-center circle--pattern\" css=\".vc_custom_1648956589196{padding-top: 3rem !important;}\"][vc_row el_class=\"pb-5\"][vc_column][vc_wp_custommenu nav_menu=\"6\"][uoh_breadcrumb_component automatic_breadcrumb=\"true\"][uoh_title_component title_dropdown=\"big\" title_decorator=\"true\"]{{title}}[\/uoh_title_component][vc_column_text css=\"\"]Frailty is increasingly becoming an important public health challenge worldwide because it is associated with older age, and with adverse outcomes such as reduced quality of life, increased mortality rates, hospitalizations, falls, depression, and dementia. Frailty is defined as dynamic state affecting an individual who experiences losses in one or more domains of human functioning (physical, psychological, social) that are caused by the influence of a range of variables, and which increases the risk of adverse outcomes. This more integral conceptual definition promotes the collaboration of scientists, social and behavioral professionals as well as clinicians from diverse specialties. In this proposal an interdisciplinary group (Biochemistry, Geriatric, Occupational Therapist, Kinesiologist, social worker, bioengineer, statistician among others) aims to evaluate frailty in Chile with a biopsychosocial approach with the final purpose to identify and manage frailty while taking into consideration all the dimensions. Additionally, we aim to design a multidomain personalized person-base intervention for a healthy aging that can uncover a circulating microRNA biomarker panel that can allow an early-detection of frailty, leading to a new multidimensional geriatric assessment. We propose the following hypothesis:  A personalized multidimensional training program reduces the frailty prevalence, increasing adherence and participation in the program among community-living older adults. This intervention will be paralleled by a distinctive miRNA profile reflecting the multiple domains of frailty, as well as improvements in diverse psychosocial traits.[\/vc_column_text][\/vc_column][\/vc_row][\/vc_section][vc_section css=\".vc_custom_1649209804184{background-color: #f6faff !important;}\" el_class=\"p-md-0 pt-md-5\"][vc_row el_class=\"container mx-auto align-items-center p-md-0 pt-5\"][vc_column el_class=\"p-0\"][\/vc_column][\/vc_row][\/vc_section][vc_section css=\".vc_custom_1649210787516{background-color: #f6faff !important;}\" el_class=\"p-md-0 pt-md-5 pb-md-5\"][vc_row el_class=\"container mx-auto align-items-center\"][vc_column][\/vc_column][\/vc_row][\/vc_section]\n                                        <\/div>\n                                    <\/div>\n                                <\/div>\n                            <\/div><div class=\"mt-3\"><i class=\"fas fa-solid fa-user-tag fa-fw me-2\"><\/i><small class=\"text-muted\">Investigador\/a Responsable<\/small><\/div><span class=\"caption-field-publish\"><\/span><\/div><\/div><\/div><\/div><\/div><div class=\" swiper-slide circle--pattern-bottom-large col-sm-12 col-md-6 img-article\"><div class=\"holder-publish \" style=\"border-bottom: 1px solid #35DB54\"><div class=\"content-holder h-100 component-border overflow-hidden row m-0 p-4 aling-items-center\"><ul class=\"p-0 list-style-none\"><li class=\"p-0 ms-1 me-2\"><i class=\"fa fa-solid fa-id-card-clip fa-fw\"><\/i> FOVI230047<\/li><li class=\"p-0 ms-1\"><i class=\"fa fa-regular fa-calendar fa-fw ms-1\"><\/i>Enero 2024 - Diciembre 2024<\/li><\/ul><div class=\"caption col-12 p-0 col-md-12 row m-0 align-items-center\"><div class=\"px-md-1\"><small class=\"badge rounded-pill fw-semibold\" style=\"background-color:#35DB54 !important; color:#FFF\">Finalizado<\/small><small class=\"ms-2 badge rounded-pill fw-semibold\" style=\"background-color:#F0F1F3 !important; color:#797979\"><i class=\"fa fa-solid fa-lg fa-money-check-dollar fa-fw me-1\"><\/i>Agencia Nacional de Investigaci\u00f3n y Desarrollo - ANID<\/small>\n                            <div class=\"accordion accordion-flush\" id=\"36989\">\n                                <div class=\"accordion-item\">\n                                    <h3 class=\"my-0 small-space pt-2 title-ss text-decoration-none accordion-header\">\n                                        <a role=\"button\" class=\"bg-transparent p-0\" href=\"\">\n                                            <i class=\"fas fa-solid fa-link fa-fw me-2\"><\/i>\n                                            Vinculaci\u00f3n internacional para la evaluaci\u00f3n de la capacidad centinela de moluscos bivalvos filtradores en el monitoreo de contaminantes emergentes en \u00e1reas costeras marinas\n                                        <\/a><\/h3>\n                                    <div id=\"collapse-36989\" class=\"accordion-collapse collapse\" data-bs-parent=\"#36989\">\n                                        <div class=\"accordion-body p-0 pt-4 pb-4\">\n                                            [vc_section el_class=\"container mx-auto align-items-center circle--pattern\" css=\".vc_custom_1648956589196{padding-top: 3rem !important;}\"][vc_row el_class=\"pb-5\"][vc_column][vc_wp_custommenu nav_menu=\"6\"][uoh_breadcrumb_component automatic_breadcrumb=\"true\"][uoh_title_component title_dropdown=\"big\" title_decorator=\"true\"]{{title}}[\/uoh_title_component][vc_column_text css=\"\"]Vinculaci\u00f3n internacional para la evaluaci\u00f3n de la capacidad centinela de moluscos bivalvos filtradores en el monitoreo de contaminantes emergentes en \u00e1reas costeras marinas[\/vc_column_text][\/vc_column][\/vc_row][\/vc_section][vc_section css=\".vc_custom_1649209804184{background-color: #f6faff !important;}\" el_class=\"p-md-0 pt-md-5\"][vc_row el_class=\"container mx-auto align-items-center p-md-0 pt-5\"][vc_column el_class=\"p-0\"][\/vc_column][\/vc_row][\/vc_section][vc_section css=\".vc_custom_1649210787516{background-color: #f6faff !important;}\" el_class=\"p-md-0 pt-md-5 pb-md-5\"][vc_row el_class=\"container mx-auto align-items-center\"][vc_column][\/vc_column][\/vc_row][\/vc_section]\n                                        <\/div>\n                                    <\/div>\n                                <\/div>\n                            <\/div><div class=\"mt-3\"><i class=\"fas fa-solid fa-user-tag fa-fw me-2\"><\/i><small class=\"text-muted\">Co-Investigador\/a<\/small><\/div><span class=\"caption-field-publish\"><\/span><\/div><\/div><\/div><\/div><\/div><div class=\" swiper-slide circle--pattern-bottom-large col-sm-12 col-md-6 img-article\"><div class=\"holder-publish \" style=\"border-bottom: 1px solid #48A2F9\"><div class=\"content-holder h-100 component-border overflow-hidden row m-0 p-4 aling-items-center\"><ul class=\"p-0 list-style-none\"><li class=\"p-0 ms-1\"><i class=\"fa fa-regular fa-calendar fa-fw ms-1\"><\/i>Enero 2024 - Diciembre 2025<\/li><\/ul><div class=\"caption col-12 p-0 col-md-12 row m-0 align-items-center\"><div class=\"px-md-1\"><small class=\"badge rounded-pill fw-semibold\" style=\"background-color:#48A2F9 !important; color:#FFF\">En Ejecuci\u00f3n<\/small><small class=\"ms-2 badge rounded-pill fw-semibold\" style=\"background-color:#F0F1F3 !important; color:#797979\"><i class=\"fa fa-solid fa-lg fa-money-check-dollar fa-fw me-1\"><\/i>Universidad de O'Higgins<\/small>\n                            <div class=\"accordion accordion-flush\" id=\"37026\">\n                                <div class=\"accordion-item\">\n                                    <h3 class=\"my-0 small-space pt-2 title-ss text-decoration-none accordion-header\">\n                                        <a role=\"button\" class=\"bg-transparent p-0\" href=\"\">\n                                            <i class=\"fas fa-solid fa-link fa-fw me-2\"><\/i>\n                                            An\u00e1lisis multi\u00f3mico de redes reguladoras post-transcripcionales microARN- ARNm en el m\u00fasculo esquel\u00e9tico humano envejecido.\n                                        <\/a><\/h3>\n                                    <div id=\"collapse-37026\" class=\"accordion-collapse collapse\" data-bs-parent=\"#37026\">\n                                        <div class=\"accordion-body p-0 pt-4 pb-4\">\n                                            [vc_section el_class=\"container mx-auto align-items-center circle--pattern\" css=\".vc_custom_1648956589196{padding-top: 3rem !important;}\"][vc_row el_class=\"pb-5\"][vc_column][vc_wp_custommenu nav_menu=\"6\"][uoh_breadcrumb_component automatic_breadcrumb=\"true\"][uoh_title_component title_dropdown=\"big\" title_decorator=\"true\"]{{title}}[\/uoh_title_component][vc_column_text css=\"\"]Durante las \u00faltimas d\u00e9cadas, la expectativa de vida promedio ha aumentado dram\u00e1ticamente, mientras\r\nque la salud no ha aumentado proporcionalmente. Para Chile se espera que para el 2050 el n\u00famero de\r\nadultos mayores superar\u00e1 el 30% de la poblaci\u00f3n con un incremento del 109% respecto al 2015,\r\nsuperando el 75% proyectado para la poblaci\u00f3n mundial. Entender el proceso de envejecimeinto y\r\nencontrar marcadores biol\u00f3gicos con capacidad diagn\u00f3stica y pron\u00f3stica, permitir\u00e1 promover estrategias\r\npara aumentar el n\u00famero de a\u00f1os de vida saludable, disminuyendo los gastos en salud asociado al\r\nenvejecimiento.\r\nVarios estudios han permitido avanzar y entender los mecanismos moleculares de p\u00e9rdidad de funci\u00f3n\r\nmuscular durante el evenjecimiento, m\u00e1s conocida como sarcopenia. Sin embargo, la complejidad del\r\nproceso y el insuficiente conocimiento de los mecanismos subjacentes dificultan el dise\u00f1o de estrategias\r\nterap\u00e9uticas eficaces. Hasta el momento, la actividad f\u00edsica y el ejercicio siguen siendo la estrategia m\u00e1s\r\neficaz para previnir y tratar la sarcopenia. Por lo cual, identificar nuevos biomarcadores musculares en\r\ncombinaci\u00f3n con marcadores cl\u00ednicos bien establecidos de par\u00e1metros f\u00edsicos y funcionales, fortalecer\u00eda\r\nla actual evaluaci\u00f3n geri\u00e1trica, al utilizar un enfoque interdiciplinario.\r\nLos microRNA (miRNA, 18\u009625 nt de largo) han ganado inter\u00e9s debido a que son mol\u00e9culas altamente\r\nconservadas en todas las especies, y act\u00faan como reguladores positivos y\/o negativos de la expresi\u00f3n\r\ng\u00e9nica. Entender la relaci\u00f3n reguladora directa entre los miARN y el ARN mensajero (mRNA) desempe\u00f1a\r\nen el m\u00fasculo esquel\u00e9tica es fundamentaltanto para el proceso de transcripci\u00f3n del ARNm y traducci\u00f3n\r\nde prote\u00ednas como para entender el deterioro de la funci\u00f3n muscular. Sin embargo, la regulaci\u00f3n de la\r\nred post-transcripcional miARN-ARNm y los mecanismos gen\u00e9ticos involucrados en el proceso de\r\nenvejecimiento del m\u00fasculo esquel\u00e9tico humano est\u00e1n lejos de ser elucidados.\r\nEn el presente estudio, nuestro objetivo es explorar e integrar coperfiles emparejados de miARN y ARNm\r\ndurante la p\u00e9rdida de funci\u00f3n muscular producidad durante el envejecimeinto en personas mayores. Este\r\nan\u00e1lisis integral permitir\u00e1 la identificaci\u00f3n de nuevos blancos de miARN y estrategias reguladoras que\r\ncontrolan la expresi\u00f3n g\u00e9nica en la p\u00e9rdidad de funci\u00f3n del m\u00fasculo esquel\u00e9tico y c\u00f3mo \u00e9stas son\r\nmodificadas por el entrenamiento de fuerza.\r\nSe hipotetiza que existen redes de regulaci\u00f3n post-transcripcional miRNA\/mRNA que se expresan de\r\nmanera diferencial en el m\u00fasculo esquel\u00e9tico de personas j\u00f3venes y personas mayores, que estar\u00edan\r\nasociadas con cambios en la funci\u00f3n muscular durante el envejecimiento. Adem\u00e1s, el entrenamiento de\r\nfuerza modifica estas redes de regulaci\u00f3n, lo que podr\u00eda contribuir a la mejora de la funci\u00f3n muscular y la\r\nprevenci\u00f3n o atenuaci\u00f3n de la sarcopenia.\r\nObjetivos generales\r\n- Identificar las redes de regulaci\u00f3n post-transcripcional miRNA\/mRNA involucradas en la\r\np\u00e9rdida de funci\u00f3n musclular en personas mayores que son moduladas por un entrenamiento\r\nde fuerza, para proponer nuevos biomarcadores de funci\u00f3n muscular durante el\r\nenvejecimeinto que se correlacionan con par\u00e1metros cl\u00ednicos\/funcionales.\r\nObjetivos espec\u00edficos\r\n1. Determinar las redes de regulaci\u00f3n post-transcripcional miRNA\/mRNA que se expresan\r\ndiferencialmente en el m\u00fasculo esquel\u00e9tico de personas j\u00f3venes y personas mayores.\r\n2. Identificar las redes de regulaci\u00f3n post-transcripcional miRNA\/mRNA que se modifican\r\ndespu\u00e9s de 12 semanas de entrenamiento de fuerza en personas mayores\r\n3. Correlacionar las redes miRNA\/mRNA identificadas con par\u00e1metros bioqu\u00edmicos, f\u00edsicos y\r\nfuncionales de funci\u00f3n muscular, antes y despu\u00e9s de 12 semanas de entrenamiento de\r\nfuerza en personas mayores\r\nEste proyecto busca Identificar nuevos biomarcadores de funci\u00f3n muscular durante el envejecimiento,\r\npodr\u00edan ser utilizados en futuros estudios y en la pr\u00e1ctica cl\u00ednica para evaluar la salud muscular en\r\npersonas mayores. Adem\u00e1s, de contribuir a una mejor comprensi\u00f3n de los mecanismos moleculares que\r\nsubyacen a la p\u00e9rdida de masa muscular en el envejecimiento y c\u00f3mo la intervenci\u00f3n del entrenamiento\r\nde fuerza puede modificar esos mecanismos. Finalmente, el uso de tecnolog\u00edas avanzadas de\r\nsecuenciaci\u00f3n (mARN y miARN) y bioinform\u00e1tica permitir\u00e1 impulsar el desarrollo y la mejora de t\u00e9cnicas\r\nde secuenciaci\u00f3n y an\u00e1lisis de datos en el campo de la gen\u00f3mica y la transcript\u00f3mica en el \u00e1rea del\r\nenvejecimiento, como tambi\u00e9n, promover la colaboraci\u00f3n a nivel nacional e internacional a trav\u00e9s de las\r\nbases de datos y recursos bioinform\u00e1ticos generados que estar\u00e1n a disposici\u00f3n de investigadores del \u00e1rea.[\/vc_column_text][\/vc_column][\/vc_row][\/vc_section][vc_section css=\".vc_custom_1649209804184{background-color: #f6faff !important;}\" el_class=\"p-md-0 pt-md-5\"][vc_row el_class=\"container mx-auto align-items-center p-md-0 pt-5\"][vc_column el_class=\"p-0\"][\/vc_column][\/vc_row][\/vc_section][vc_section css=\".vc_custom_1649210787516{background-color: #f6faff !important;}\" el_class=\"p-md-0 pt-md-5 pb-md-5\"][vc_row el_class=\"container mx-auto align-items-center\"][vc_column][\/vc_column][\/vc_row][\/vc_section]\n                                        <\/div>\n                                    <\/div>\n                                <\/div>\n                            <\/div><div class=\"mt-3\"><i class=\"fas fa-solid fa-user-tag fa-fw me-2\"><\/i><small class=\"text-muted\">Investigador\/a Responsable<\/small><\/div><span class=\"caption-field-publish\"><\/span><\/div><\/div><\/div><\/div><\/div><div class=\" swiper-slide circle--pattern-bottom-large col-sm-12 col-md-6 img-article\"><div class=\"holder-publish \" style=\"border-bottom: 1px solid #EFB956\"><div class=\"content-holder h-100 component-border overflow-hidden row m-0 p-4 aling-items-center\"><ul class=\"p-0 list-style-none\"><li class=\"p-0 ms-1 me-2\"><i class=\"fa fa-solid fa-id-card-clip fa-fw\"><\/i> 23CVC-245806<\/li><li class=\"p-0 ms-1\"><i class=\"fa fa-regular fa-calendar fa-fw ms-1\"><\/i>Octubre 2023 - Diciembre 2026<\/li><\/ul><div class=\"caption col-12 p-0 col-md-12 row m-0 align-items-center\"><div class=\"px-md-1\"><small class=\"badge rounded-pill fw-semibold\" style=\"background-color:#EFB956 !important; color:#FFF\">Adjudicado<\/small><small class=\"ms-2 badge rounded-pill fw-semibold\" style=\"background-color:#F0F1F3 !important; color:#797979\"><i class=\"fa fa-solid fa-lg fa-money-check-dollar fa-fw me-1\"><\/i>Corporaci\u00f3n de Fomento de la Producci\u00f3n - CORFO<\/small>\n                            <div class=\"accordion accordion-flush\" id=\"37021\">\n                                <div class=\"accordion-item\">\n                                    <h3 class=\"my-0 small-space pt-2 title-ss text-decoration-none accordion-header\">\n                                        <a role=\"button\" class=\"bg-transparent p-0\" href=\"\">\n                                            <i class=\"fas fa-solid fa-link fa-fw me-2\"><\/i>\n                                            Strong-Bee: Gel multi-ingredientes formulado en base a compuestos naturales, especialmente desarrollado para favorecer la recuperaci\u00f3n muscular y el rendimiento de deportistas\n                                        <\/a><\/h3>\n                                    <div id=\"collapse-37021\" class=\"accordion-collapse collapse\" data-bs-parent=\"#37021\">\n                                        <div class=\"accordion-body p-0 pt-4 pb-4\">\n                                            [vc_section el_class=\"container mx-auto align-items-center circle--pattern\" css=\".vc_custom_1648956589196{padding-top: 3rem !important;}\"][vc_row el_class=\"pb-5\"][vc_column][vc_wp_custommenu nav_menu=\"6\"][uoh_breadcrumb_component automatic_breadcrumb=\"true\"][uoh_title_component title_dropdown=\"big\" title_decorator=\"true\"]{{title}}[\/uoh_title_component][vc_column_text css=\"\"]Desarrollar y validar mediante ensayos in vivo un gel energ\u00e9tico para deportistas de alto rendimiento, formulado en\r\nbase a miel y extractos naturales, para ser utilizado como potenciador del rendimiento deportivo y la recuperaci\u00f3n\r\nmuscular post ejercicio. Los principales objetivos son: 1) Formular el gel energ\u00e9tico en base a los requerimientos\r\nnutricionales espec\u00ed&#1048789;cos de deportistas de alto rendimiento, caracteriz\u00e1ndolo en t\u00e9rminos nutricionales, capacidad\r\nantioxidante y ausencia de sustancias no deseadas. 2)Evaluar la tolerabilidad in vivo del producto en t\u00e9rminos de\r\npalatabilidad y efectos gastrointestinales. 3)Dise\u00f1ar e implementar el proceso mezclamiento y envasado para escalar\r\nla producci\u00f3n. 4)Cuanti&#1048789;car los efectos del producto desarrollado respecto del aporte sobre el rendimiento deportivo,\r\nla recuperaci\u00f3n muscular post ejercicio y s\u00edntomas de malestar gastrointestinal. y 5) Fortalecer el modelo de negocios.[\/vc_column_text][\/vc_column][\/vc_row][\/vc_section][vc_section css=\".vc_custom_1649209804184{background-color: #f6faff !important;}\" el_class=\"p-md-0 pt-md-5\"][vc_row el_class=\"container mx-auto align-items-center p-md-0 pt-5\"][vc_column el_class=\"p-0\"][\/vc_column][\/vc_row][\/vc_section][vc_section css=\".vc_custom_1649210787516{background-color: #f6faff !important;}\" el_class=\"p-md-0 pt-md-5 pb-md-5\"][vc_row el_class=\"container mx-auto align-items-center\"][vc_column][\/vc_column][\/vc_row][\/vc_section]\n                                        <\/div>\n                                    <\/div>\n                                <\/div>\n                            <\/div><div class=\"mt-3\"><i class=\"fas fa-solid fa-user-tag fa-fw me-2\"><\/i><small class=\"text-muted\">Co-Investigador\/a<\/small><\/div><span class=\"caption-field-publish\"><\/span><\/div><\/div><\/div><\/div><\/div><div class=\"pagination justify-content-center my-5\"><span aria-current=\"page\" class=\"page-numbers current\">1<\/span>\n<a class=\"page-numbers\" href=\"https:\/\/www.uoh.cl\/investigacion\/wp-json\/wp\/v2\/pages\/16\/\/page\/2\">2<\/a>\n<a class=\"page-numbers\" 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todos los proyectos<\/a><\/div>[\/vc_column][\/vc_row][\/vc_section][vc_section el_id=&#8221;publicaciones&#8221; el_class=&#8221;container mx-auto p-md-0 align-items-center&#8221;][vc_row][vc_column]<link rel=\"stylesheet\" id=\"font-awesome-css\" href=\"https:\/\/cdnjs.cloudflare.com\/ajax\/libs\/font-awesome\/6.5.1\/css\/all.min.css\" type=\"text\/css\" media=\"all\"><div class=\"row m-0 p-0\"><div class=\"col-12 col-md-9 pt-5 pt-md-0 px-md-0 \"><h2 class=\"title title--decorator title--ms d-inline-block\">\u00daltimas Publicaciones<\/h2><\/div><div class=\"swipper-buttons col-12 col-md-3 row m-0  justify-content-center justify-content-md-end pe-0 \">\n                    <div class=\"swiper-button-prev-publish-44 swiper-button-prev-component\"><span class=\"icon icon--inline icon--slide icon--slide-left\"><svg version=\"1.1\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" x=\"0px\" y=\"0px\" width=\"22px\"height=\"22px\" viewBox=\"0 0 22 22\" style=\"overflow:visible;enable-background:new 0 0 80 64.6;\" xml:space=\"preserve\"><g clip-path=\"url(#acA)\"><path fill-rule=\"evenodd\" d=\"M21.913 11.266a.93.93 0 000-.711c-.022-.056-.063-.097-.091-.144s-.053-.103-.097-.15L12.306.294c-.357-.379-.955-.394-1.334-.038s-.394.955-.038 1.334l7.917 8.374H.927a.95.95 0 00-.908.983.946.946 0 00.908.908h17.924l-8.089 8.552c-.357.379-.341.977.034 1.334s.977.341 1.334-.034l9.594-10.148c.044-.044.063-.1.097-.15.028-.047.069-.088.091-.141z\"\/><\/g><defs><clipPath id=\"acA\"><path fill=\"#fff\" d=\"M0 0h22v22H0z\"\/><\/clipPath><\/defs><\/svg><\/span><\/div>\n                    <div class=\"swiper-pagination-component-publish-44\"><\/div>\n                    <div class=\"swiper-button-next-publish-44 swiper-button-prev-component\"><span class=\"icon icon--inline icon--slide \"><svg version=\"1.1\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" x=\"0px\" y=\"0px\" width=\"22px\"height=\"22px\" 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   rel=\"\">\n            <span class=\"icon__arrow-prelink\"><svg version=\"1.1\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" x=\"0px\" y=\"0px\" width=\"80px\" height=\"64.6px\" viewBox=\"0 0 80 64.6\" style=\"overflow:visible;enable-background:new 0 0 80 64.6;\" xml:space=\"preserve\"><defs><\/defs><path d=\"M4,36.3h62.3L44.9,57.7c-1.6,1.6-1.6,4.1,0,5.7c1.6,1.6,4.1,1.6,5.7,0l28.3-28.3l0,0c0.2-0.2,0.4-0.4,0.5-0.6 c0.1-0.1,0.1-0.2,0.2-0.3c0.1-0.1,0.1-0.2,0.2-0.4c0.1-0.1,0.1-0.3,0.1-0.4c0-0.1,0.1-0.2,0.1-0.3c0.1-0.3,0.1-0.5,0.1-0.8l0,0 c0,0,0,0,0,0c0-0.3,0-0.5-0.1-0.8c0-0.1-0.1-0.2-0.1-0.3c0-0.1-0.1-0.3-0.1-0.4c-0.1-0.1-0.1-0.3-0.2-0.4c-0.1-0.1-0.1-0.2-0.2-0.3 c-0.1-0.2-0.3-0.4-0.5-0.6L50.5,1.2c-1.6-1.6-4.1-1.6-5.7,0c-1.6,1.6-1.6,4.1,0,5.7l21.5,21.5H4c-2.2,0-4,1.8-4,4S1.8,36.3,4,36.3z\"><\/path><\/svg><\/span>\n            Ir a todas las publicaciones<\/a><\/div>[\/vc_column][\/vc_row][\/vc_section][vc_section el_id=&#8221;noticias&#8221; el_class=&#8221;pt-5 pb-5&#8243; css=&#8221;.vc_custom_1650286969532{background-color: #f6faff !important;}&#8221;][vc_row el_class=&#8221;container mx-auto p-md-0 align-items-center pb-5 pt-5&#8243;][vc_column el_class=&#8221;pt-5 pb-5&#8243;]<div class=\"row m-0 p-0\"><div class=\"col-12 col-md-9 pt-5 pt-md-0\"><h2 class=\"title title--decorator title--ms d-inline-block\">Novedades destacadas<\/h2><\/div><\/div><div class=\"content-holder\"><div class=\"row  swipper-news-list not--activate-hack \"><div class=\"row -wrapper\"><div class=\"  col-sm-6 col-md-4 img-article\">\n                                        <div class=\"content-news-display row m-0 p-0\"><div class=\"holder p-0 \"><div class=\"img-wrap img-wrap-news\">\n                                        <div class=\"caption__news-category\">\n                                        <a href=\"https:\/\/www.uoh.cl\/investigacion\/category\/observatorio-laboral\/\">\n                                        Observatorio Laboral<\/a><\/div><img decoding=\"async\" class=\"w-100 h-100 lazyload\" data-src=\"https:\/\/www.uoh.cl\/investigacion\/wp-content\/uploads\/sites\/12\/2026\/05\/Observatorio-Laboral-1-scaled.jpg\" alt=\"Desocupaci\u00f3n se mantiene estable y brecha de g\u00e9nero se cierra por primera vez\" style=\"--smush-placeholder-width: 2560px; --smush-placeholder-aspect-ratio: 2560\/1707;object-fit: cover; object-position: center;\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMSIgaGVpZ2h0PSIxIiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjwvc3ZnPg==\"><\/div><\/div><div class=\"caption py-3 caption__news py-md-3 pb-md-5\">\n                                    <span class=\"caption__date\">Lunes 11, Mayo<\/span>\n                                     <a href=\"https:\/\/www.uoh.cl\/investigacion\/desocupacion-se-mantiene-estable-y-brecha-de-genero-se-cierra-por-primera-vez\/\">\n                                    <h3 class=\"small-space\">Desocupaci\u00f3n se mantiene estable y brecha de g\u00e9nero se cierra por primera vez<\/h3><\/a>\n\n                                    <p>Mientras que la desocupaci\u00f3n en los hombres subi\u00f3 2,6 puntos, la de las mujeres baj\u00f3 3,6 puntos.<\/p>\n                                    <a class=\"link link--bold mt-md-3\" href=\"https:\/\/www.uoh.cl\/investigacion\/desocupacion-se-mantiene-estable-y-brecha-de-genero-se-cierra-por-primera-vez\/\">Saber m\u00e1s <span class=\"icon icon--inline icon--link\"><svg version=\"1.1\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" x=\"0px\" y=\"0px\" width=\"22px\"height=\"22px\" viewBox=\"0 0 22 22\" style=\"overflow:visible;enable-background:new 0 0 80 64.6;\" xml:space=\"preserve\"><g clip-path=\"url(#acA)\"><path fill-rule=\"evenodd\" d=\"M21.913 11.266a.93.93 0 000-.711c-.022-.056-.063-.097-.091-.144s-.053-.103-.097-.15L12.306.294c-.357-.379-.955-.394-1.334-.038s-.394.955-.038 1.334l7.917 8.374H.927a.95.95 0 00-.908.983.946.946 0 00.908.908h17.924l-8.089 8.552c-.357.379-.341.977.034 1.334s.977.341 1.334-.034l9.594-10.148c.044-.044.063-.1.097-.15.028-.047.069-.088.091-.141z\"\/><\/g><defs><clipPath id=\"acA\"><path fill=\"#fff\" d=\"M0 0h22v22H0z\"\/><\/clipPath><\/defs><\/svg><\/span><\/a><\/div><\/div><\/div><div class=\"  col-sm-6 col-md-4 img-article\">\n                                        <div class=\"content-news-display row m-0 p-0\"><div class=\"holder p-0 \"><div class=\"img-wrap img-wrap-news\">\n                                        <div class=\"caption__news-category\">\n                                        <a href=\"https:\/\/www.uoh.cl\/investigacion\/category\/investigacion\/\">\n                                        Investigaci\u00f3n<\/a><\/div><img decoding=\"async\" class=\"w-100 h-100 lazyload\" data-src=\"https:\/\/www.uoh.cl\/investigacion\/wp-content\/uploads\/sites\/12\/2026\/04\/FWIS2026-web-op.jpg\" alt=\"Comienza proceso de postulaciones al Premio For Women in Science 2026\" style=\"--smush-placeholder-width: 800px; --smush-placeholder-aspect-ratio: 800\/444;object-fit: cover; object-position: center;\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMSIgaGVpZ2h0PSIxIiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjwvc3ZnPg==\"><\/div><\/div><div class=\"caption py-3 caption__news py-md-3 pb-md-5\">\n                                    <span class=\"caption__date\">Jueves 30, Abril<\/span>\n                                     <a href=\"https:\/\/www.uoh.cl\/investigacion\/comienza-proceso-de-postulaciones-al-premio-for-women-in-science-2026\/\">\n                                    <h3 class=\"small-space\">Comienza proceso de postulaciones al Premio For Women in Science 2026<\/h3><\/a>\n\n                                    <p>La convocatoria, abierta entre el 22 de abril y el 28 de mayo de 2026, busca impulsar la trayectoria y aporte cient\u00edfico de investigadoras chilenas.<\/p>\n                                    <a class=\"link link--bold mt-md-3\" href=\"https:\/\/www.uoh.cl\/investigacion\/comienza-proceso-de-postulaciones-al-premio-for-women-in-science-2026\/\">Saber m\u00e1s <span class=\"icon icon--inline icon--link\"><svg version=\"1.1\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" x=\"0px\" y=\"0px\" width=\"22px\"height=\"22px\" viewBox=\"0 0 22 22\" style=\"overflow:visible;enable-background:new 0 0 80 64.6;\" xml:space=\"preserve\"><g clip-path=\"url(#acA)\"><path fill-rule=\"evenodd\" d=\"M21.913 11.266a.93.93 0 000-.711c-.022-.056-.063-.097-.091-.144s-.053-.103-.097-.15L12.306.294c-.357-.379-.955-.394-1.334-.038s-.394.955-.038 1.334l7.917 8.374H.927a.95.95 0 00-.908.983.946.946 0 00.908.908h17.924l-8.089 8.552c-.357.379-.341.977.034 1.334s.977.341 1.334-.034l9.594-10.148c.044-.044.063-.1.097-.15.028-.047.069-.088.091-.141z\"\/><\/g><defs><clipPath id=\"acA\"><path fill=\"#fff\" d=\"M0 0h22v22H0z\"\/><\/clipPath><\/defs><\/svg><\/span><\/a><\/div><\/div><\/div><div 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href=\"https:\/\/www.uoh.cl\/investigacion\/uoh-conmemora-dia-mundial-de-la-propiedad-intelectual-destacando-avances-en-proteccion\/\">Saber m\u00e1s <span class=\"icon icon--inline icon--link\"><svg version=\"1.1\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" x=\"0px\" y=\"0px\" width=\"22px\"height=\"22px\" viewBox=\"0 0 22 22\" style=\"overflow:visible;enable-background:new 0 0 80 64.6;\" xml:space=\"preserve\"><g clip-path=\"url(#acA)\"><path fill-rule=\"evenodd\" d=\"M21.913 11.266a.93.93 0 000-.711c-.022-.056-.063-.097-.091-.144s-.053-.103-.097-.15L12.306.294c-.357-.379-.955-.394-1.334-.038s-.394.955-.038 1.334l7.917 8.374H.927a.95.95 0 00-.908.983.946.946 0 00.908.908h17.924l-8.089 8.552c-.357.379-.341.977.034 1.334s.977.341 1.334-.034l9.594-10.148c.044-.044.063-.1.097-.15.028-.047.069-.088.091-.141z\"\/><\/g><defs><clipPath id=\"acA\"><path fill=\"#fff\" d=\"M0 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