{"id":766,"date":"2022-04-29T13:36:49","date_gmt":"2022-04-29T16:36:49","guid":{"rendered":"https:\/\/www.uoh.cl\/investigacion\/academico\/valentina-giaconi-2\/"},"modified":"2026-05-14T05:02:51","modified_gmt":"2026-05-14T08:02:51","slug":"pablo-rupin-gutierrez","status":"publish","type":"academics","link":"https:\/\/www.uoh.cl\/investigacion\/academico\/pablo-rupin-gutierrez\/","title":{"rendered":"Pablo Rupin Guti\u00e9rrez"},"content":{"rendered":"<div class=\"wpb-content-wrapper\"><p>[vc_section el_class=&#8221;container mx-auto align-items-center circle&#8211;pattern&#8221; css=&#8221;.vc_custom_1650056176159{padding-top: 3rem !important;}&#8221;][vc_row][vc_column][vc_wp_custommenu nav_menu=&#8221;5&#8243;]<div class=\"breadcrumb\"><ol itemscope itemtype=\"https:\/\/schema.org\/BreadcrumbList\"><li itemprop=\"itemListElement\" itemscope itemtype=\"https:\/\/schema.org\/ListItem\"><a itemprop=\"item\" href=\"http:\/\/www.uoh.cl\"><span itemprop=\"name\">Inicio<\/span><\/a><meta itemprop=\"position\" content=\"1\" \/><li itemprop=\"itemListElement\" itemscope itemtype=\"https:\/\/schema.org\/ListItem\"><a itemprop=\"item\" href=\"https:\/\/www.uoh.cl\/investigacion\"><span itemprop=\"name\">Investigaci\u00f3n<\/span><\/a><meta itemprop=\"position\" content=\"2\" \/><li itemprop=\"itemListElement\" itemscope itemtype=\"https:\/\/schema.org\/ListItem\"><a itemprop=\"item\" href=\"https:\/\/www.uoh.cl\/investigacion\"><span itemprop=\"name\">Investigaci\u00f3n<\/span><\/a><meta itemprop=\"position\" content=\"3\" \/><li itemprop=\"itemListElement\" itemscope itemtype=\"https:\/\/schema.org\/ListItem\"><a itemprop=\"item\" href=\"https:\/\/www.uoh.cl\/investigacion\/academicos\"><span itemprop=\"name\">Acad\u00e9micos<\/span><\/a><meta itemprop=\"position\" content=\"4\" \/><li itemprop=\"itemListElement\" itemscope itemtype=\"https:\/\/schema.org\/ListItem\"><span itemprop=\"name\">Pablo Rupin Guti\u00e9rrez <\/span><meta itemprop=\"position\" content=\"5\" \/><\/ol><\/div><ul class=\"p-0 list-style-none d-inline-block\"><li class=\"p-0\"><a href=\"https:\/\/www.uoh.cl\/instituto-de-ciencias-de-la-educacion\" class=\"px-1 py-2\">\n                            Instituto de Ciencias de la Educaci\u00f3n\n                        <\/a><\/li><\/ul><div class=\"uoh_title_component-container\"><h1 class=\"title title--ms d-inline-block big\">Pablo Rupin Guti\u00e9rrez<em class=\"position__title\"> <span>\u25cf<\/span> Profesor Asistente<\/em><\/h1><\/div>[vc_row_inner el_class=&#8221;border-separator m-0 mt-4&#8243;][vc_column_inner width=&#8221;1\/6&#8243;]<div class=\"vc_single_image-wrapper vc_box_rounded  vc_box_border_grey\"><img decoding=\"async\" width=\"1000\" height=\"1000\" data-src=\"https:\/\/www.uoh.cl\/investigacion\/wp-content\/uploads\/sites\/12\/2022\/04\/Pablo-Rupin-2.jpg\" class=\"attachment-large size-large wp-post-image lazyload\" alt=\"\" data-srcset=\"https:\/\/www.uoh.cl\/investigacion\/wp-content\/uploads\/sites\/12\/2022\/04\/Pablo-Rupin-2.jpg 1000w, https:\/\/www.uoh.cl\/investigacion\/wp-content\/uploads\/sites\/12\/2022\/04\/Pablo-Rupin-2-300x300.jpg 300w, https:\/\/www.uoh.cl\/investigacion\/wp-content\/uploads\/sites\/12\/2022\/04\/Pablo-Rupin-2-150x150.jpg 150w, https:\/\/www.uoh.cl\/investigacion\/wp-content\/uploads\/sites\/12\/2022\/04\/Pablo-Rupin-2-768x768.jpg 768w, https:\/\/www.uoh.cl\/investigacion\/wp-content\/uploads\/sites\/12\/2022\/04\/Pablo-Rupin-2-600x600.jpg 600w\" data-sizes=\"(max-width: 1000px) 100vw, 1000px\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMSIgaGVpZ2h0PSIxIiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjwvc3ZnPg==\" style=\"--smush-placeholder-width: 1000px; --smush-placeholder-aspect-ratio: 1000\/1000;\" \/><\/div>[\/vc_column_inner][vc_column_inner width=&#8221;2\/3&#8243;]<div class=\"block--info\">\n                                <div class=\"sub_title__grade\">Grado Acad\u00e9mico<\/div>\n                                <h3>Doctor en Ciencias de la Educaci\u00f3n, Universit\u00e9 Paris 13 Paris Sorbonne Cit\u00e9 \/ Magister en Gesti\u00f3n y Pol\u00edticas P\u00fablicas, Universidad de Chile.<\/h3> <\/div><div class=\"block--info\">\n                                <div class=\"sub_title__grade\">T\u00edtulo(s) Profesional<\/div>\n                                <h3>Soci\u00f3logo, Universidad Cat\u00f3lica de Chile.<\/h3> <\/div>[\/vc_column_inner][vc_column_inner width=&#8221;1\/6&#8243;]<div class=\"uoh_social_network_component uoh_row col-12 justify-content-end m-0 p-0\"> <div class=\"icon__facebook-share-button\">\n                       <a href=\"https:\/\/www.facebook.com\/sharer\/sharer.php?u=https:\/\/www.uoh.cl\/investigacion\/academico\/pablo-rupin-gutierrez\/\" target=\"_blank\"> <div class=\"icon__facebook-svg\"><svg version=\"1.1\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" x=\"0px\" y=\"0px\" width=\"22.4px\" height=\"48.3px\" viewBox=\"0 0 22.4 48.3\" style=\"overflow:visible;enable-background:new 0 0 22.4 48.3;\" xml:space=\"preserve\">\n                <defs>\n                <\/defs>\n                <path class=\"st0\" d=\"M22.4,15.6h-7.6v-5c0-1.9,1.2-2.3,2.1-2.3c0.9,0,5.4,0,5.4,0V0l-7.4,0C6.6,0,4.8,6.2,4.8,10.1v5.5H0v8.5h4.8\n                    c0,10.9,0,24.1,0,24.1h10c0,0,0-13.3,0-24.1h6.8L22.4,15.6z\"><\/path>\n                <\/svg><\/a><\/div>\n                    <\/div><div class=\"icon__twitter-share-button\">\n                        <div class=\"icon__twitter-svg\"><a target=\"_blank\" href=\"http:\/\/twitter.com\/share?url=https:\/\/www.uoh.cl\/investigacion\/academico\/pablo-rupin-gutierrez\/\"><svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" height=\"1em\" viewBox=\"0 0 512 512\"><!--! 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Ejerce como investigador del Consejo Nacional de Televisi\u00f3n (2001-2007), per\u00edodo durante el cual cursa el Mag\u00edster en Gesti\u00f3n y Pol\u00edticas P\u00fablicas de la Universidad de Chile. En 2007 ingresa a la JUNJI, desempe\u00f1\u00e1ndose como Encargado de la Secci\u00f3n de Estudios y Estad\u00edsticas del Departamento de Planificaci\u00f3n. En 2008 se adjudica la beca Presidente de la Rep\u00fablica para efectuar su doctorado en la Universidad Paris 13 (Universit\u00e9 Sorbonne Paris Nord), Francia. De regreso en Chile, en 2016 se incorpora al Centro de Investigaci\u00f3n Avanzada en Educaci\u00f3n (CIAE) de la Universidad de Chile. Forma parte del ICED \u2013 UOH desde diciembre de 2018.<\/p>[\/vc_column_inner][\/vc_row_inner][\/vc_column][\/vc_row][\/vc_section][vc_section css=&#8221;.vc_custom_1650056119592{background-color: #ffffff !important;}&#8221; el_class=&#8221;p-md-0 pt-md-5 pb-md-5&#8243;][vc_row el_class=&#8221;container mx-auto align-items-start&#8221;][vc_column width=&#8221;1\/6&#8243; el_class=&#8221;p-0&#8243;]<div class=\"uoh_link_component pe-4 d-inline-block py-1 button_icon inline\"><i class=\"me-2 fas fa-newspaper\" style=\"color: #42a0f8\"><\/i><span>Publicaciones<\/span><\/div><div class=\"wpb_text_column wpb_content_element  citas mb-3 pb-3\"><div class=\"wpb_wrapper\"><p>8<\/p><\/div><\/div><div class=\"uoh_link_component pe-4 d-inline-block py-1 button_icon inline\"><i class=\"me-2 fas fa-project-diagram\" style=\"color: #42a0f8\"><\/i><span>Proyectos<\/span><\/div><div class=\"wpb_text_column wpb_content_element  citas mb-3 pb-3\"><div class=\"wpb_wrapper\"><p>9<\/p><\/div><\/div><div class=\"uoh_link_component pe-4 d-inline-block py-1 button_icon inline\"><i class=\"me-2 fas fa-book\" style=\"color: #42a0f8\"><\/i><span>Libros y Monograf\u00edas<\/span><\/div><div class=\"wpb_text_column wpb_content_element  citas mb-3 pb-3\"><div class=\"wpb_wrapper\"><p>1<\/p><\/div><\/div><div class=\"uoh_link_component pe-4 d-inline-block py-1 button_icon inline\"><i class=\"me-2 fas fa-book-bookmark\" style=\"color: #42a0f8\"><\/i><span>Cap\u00edtulos de Libros<\/span><\/div><div class=\"wpb_text_column wpb_content_element  citas mb-3 pb-3\"><div class=\"wpb_wrapper\"><p>4<\/p><\/div><\/div>[\/vc_column][vc_column width=&#8221;5\/6&#8243;][vc_tta_tabs active_section=&#8221;1&#8243; el_class=&#8221;tabs-inner-academic&#8221;][vc_tta_section title=&#8221;Publicaciones&#8221; tab_id=&#8221;publicaciones&#8221;]<link rel=\"stylesheet\" id=\"font-awesome-css\" href=\"https:\/\/cdnjs.cloudflare.com\/ajax\/libs\/font-awesome\/6.5.1\/css\/all.min.css\" type=\"text\/css\" 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class=\"caption-field-publish\"><\/span><\/div><\/div><\/div><\/div><\/div><div class=\"  circle--pattern-bottom-large col-sm-12 col-md-12 img-article\"><div class=\"holder-publish col-md-12\" style=\"border-bottom: 1px solid #B8B8B8\"><div class=\"content-holder h-100 component-border overflow-hidden row m-0 p-4 aling-items-center\"><ul class=\"p-0 list-style-none\"><li class=\"p-0 me-2\"><i class=\"fas fa-solid fa-newspaper fa-fw\"><\/i> REVISTA Revue Fran\u00e7aise d\u0092\u00c9ducation Compar\u00e9e<\/li><li class=\"p-0\"><i class=\"fa fa-regular fa-calendar fa-fw\"><\/i> 2021<\/li><\/ul><div class=\"caption col-12 p-0 col-md-12 row m-0 align-items-center\"><div class=\"px-md-1\"><h3 class=\"small-space title-ss text-decoration-none m-0\">La participation parentale dans des structures pr\u00e9scolaires \u00ab communautaires \u00bb au Chili<\/h3><br><i class=\"fas fa-solid fa-users fa-fw me-2\"><\/i><small class=\"text-muted\"> \u2022 Pablo Iv\u00e1n Rup\u00edn Guti\u00e9rrez <\/small><br><span class=\"caption-field-publish\"><\/span><\/div><\/div><\/div><\/div><\/div><div class=\"  circle--pattern-bottom-large col-sm-12 col-md-12 img-article\"><div class=\"holder-publish col-md-12\" style=\"border-bottom: 1px solid #B8B8B8\"><div class=\"content-holder h-100 component-border overflow-hidden row m-0 p-4 aling-items-center\"><ul class=\"p-0 list-style-none\"><li class=\"p-0 me-2\"><i class=\"fas fa-solid fa-newspaper fa-fw\"><\/i> REVISTA Revue Fran\u00e7aise d\u0092\u00c9ducation Compar\u00e9e<\/li><li class=\"p-0\"><i class=\"fa fa-regular fa-calendar fa-fw\"><\/i> 2021<\/li><\/ul><div class=\"caption col-12 p-0 col-md-12 row m-0 align-items-center\"><div class=\"px-md-1\"><h3 class=\"small-space title-ss text-decoration-none m-0\">La participation parentale dans des structures pr\u00e9scolaires \u00ab communautaires \u00bb au Chili<\/h3><br><i class=\"fas fa-solid fa-users fa-fw me-2\"><\/i><small class=\"text-muted\"> \u2022 Pablo Iv\u00e1n Rup\u00edn Guti\u00e9rrez <\/small><br><span class=\"caption-field-publish\"><\/span><\/div><\/div><\/div><\/div><\/div><div class=\"  circle--pattern-bottom-large col-sm-12 col-md-12 img-article\"><div class=\"holder-publish col-md-12\" style=\"border-bottom: 1px solid #B8B8B8\"><div class=\"content-holder h-100 component-border overflow-hidden row m-0 p-4 aling-items-center\"><ul class=\"p-0 list-style-none\"><li class=\"p-0 me-2\"><i class=\"fas fa-solid fa-newspaper fa-fw\"><\/i> REVISTA European Early Childhood Education Research Journal<\/li><li class=\"p-0\"><i class=\"fa fa-regular fa-calendar fa-fw\"><\/i> 2017<\/li><\/ul><div class=\"caption col-12 p-0 col-md-12 row m-0 align-items-center\"><div class=\"px-md-1\"><h3 class=\"small-space title-ss text-decoration-none m-0\">Children of two to three years of age in France: early childhood settings and age divisions<\/h3><br><i class=\"fas fa-solid fa-users fa-fw me-2\"><\/i><small class=\"text-muted\"> \u2022 Pascale Garnier \u2022  Sylvie Rayna \u2022  Gilles Broug\u00e8re \u2022  Pablo Iv\u00e1n Rup\u00edn Guti\u00e9rrez <\/small><br><p class=\"text-muted pt-3 position-relative\" style=\"z-index:2;\"><a href=\"http:\/\/dx.doi.org\/10.1080\/1350293X.2016.1195064\" target=\"_blank\"><i class=\"fas fa-solid fa-link fa-fw\"><\/i> http:\/\/dx.doi.org\/10.1080\/1350293X.2016.1195064<\/a><\/small><span class=\"caption-field-publish\"><\/span><\/div><\/div><\/div><\/div><\/div><div class=\"  circle--pattern-bottom-large col-sm-12 col-md-12 img-article\"><div class=\"holder-publish col-md-12\" style=\"border-bottom: 1px solid #B8B8B8\"><div class=\"content-holder h-100 component-border overflow-hidden row m-0 p-4 aling-items-center\"><ul class=\"p-0 list-style-none\"><li class=\"p-0 me-2\"><i class=\"fas fa-solid fa-newspaper fa-fw\"><\/i> REVISTA European Early Childhood Education Research Journal<\/li><li class=\"p-0\"><i class=\"fa fa-regular fa-calendar fa-fw\"><\/i> 2017<\/li><\/ul><div class=\"caption col-12 p-0 col-md-12 row m-0 align-items-center\"><div class=\"px-md-1\"><h3 class=\"small-space title-ss text-decoration-none m-0\">Children of two to three years of age in France: early childhood settings and age divisions<\/h3><br><i class=\"fas fa-solid fa-users fa-fw me-2\"><\/i><small class=\"text-muted\"> \u2022 Pascale Garnier \u2022  Sylvie Rayna \u2022  Gilles Broug\u00e8re \u2022  Pablo Iv\u00e1n Rup\u00edn Guti\u00e9rrez <\/small><br><p class=\"text-muted pt-3 position-relative\" style=\"z-index:2;\"><a href=\"http:\/\/dx.doi.org\/10.1080\/1350293X.2016.1195064\" target=\"_blank\"><i class=\"fas fa-solid fa-link fa-fw\"><\/i> http:\/\/dx.doi.org\/10.1080\/1350293X.2016.1195064<\/a><\/small><span class=\"caption-field-publish\"><\/span><\/div><\/div><\/div><\/div><\/div><div class=\"  circle--pattern-bottom-large col-sm-12 col-md-12 img-article\"><div class=\"holder-publish col-md-12\" style=\"border-bottom: 1px solid #B8B8B8\"><div class=\"content-holder h-100 component-border overflow-hidden row m-0 p-4 aling-items-center\"><ul class=\"p-0 list-style-none\"><li class=\"p-0 me-2\"><i class=\"fas fa-solid fa-newspaper fa-fw\"><\/i> REVISTA La nouvelle revue de l'adaptation et de la scolarisation<\/li><li class=\"p-0\"><i class=\"fa fa-regular fa-calendar fa-fw\"><\/i> 2016<\/li><\/ul><div class=\"caption col-12 p-0 col-md-12 row m-0 align-items-center\"><div class=\"px-md-1\"><h3 class=\"small-space title-ss text-decoration-none m-0\">Participation des parents, inclusion et prise en compte de la diversit\u00e9 dans le pr\u00e9scolaire chilien<\/h3><br><i class=\"fas fa-solid fa-users fa-fw me-2\"><\/i><small class=\"text-muted\"> \u2022 Pablo Iv\u00e1n Rup\u00edn Guti\u00e9rrez <\/small><br><p class=\"text-muted pt-3 position-relative\" style=\"z-index:2;\"><a href=\"http:\/\/dx.doi.org\/10.3917\/nras.073.0049\" target=\"_blank\"><i class=\"fas fa-solid fa-link fa-fw\"><\/i> http:\/\/dx.doi.org\/10.3917\/nras.073.0049<\/a><\/small><span class=\"caption-field-publish\"><\/span><\/div><\/div><\/div><\/div><\/div><div class=\"  circle--pattern-bottom-large col-sm-12 col-md-12 img-article\"><div class=\"holder-publish col-md-12\" style=\"border-bottom: 1px solid #B8B8B8\"><div class=\"content-holder h-100 component-border overflow-hidden row m-0 p-4 aling-items-center\"><ul class=\"p-0 list-style-none\"><li class=\"p-0 me-2\"><i class=\"fas fa-solid fa-newspaper fa-fw\"><\/i> REVISTA La nouvelle revue de l'adaptation et de la scolarisation<\/li><li class=\"p-0\"><i class=\"fa fa-regular fa-calendar fa-fw\"><\/i> 2016<\/li><\/ul><div class=\"caption col-12 p-0 col-md-12 row m-0 align-items-center\"><div class=\"px-md-1\"><h3 class=\"small-space title-ss text-decoration-none m-0\">Participation des parents, inclusion et prise en compte de la diversit\u00e9 dans le pr\u00e9scolaire chilien<\/h3><br><i class=\"fas fa-solid fa-users fa-fw me-2\"><\/i><small class=\"text-muted\"> \u2022 Pablo Iv\u00e1n Rup\u00edn Guti\u00e9rrez <\/small><br><p class=\"text-muted pt-3 position-relative\" style=\"z-index:2;\"><a href=\"http:\/\/dx.doi.org\/10.3917\/nras.073.0049\" target=\"_blank\"><i class=\"fas fa-solid fa-link fa-fw\"><\/i> http:\/\/dx.doi.org\/10.3917\/nras.073.0049<\/a><\/small><span class=\"caption-field-publish\"><\/span><\/div><\/div><\/div><\/div><\/div><div class=\"  circle--pattern-bottom-large col-sm-12 col-md-12 img-article\"><div class=\"holder-publish col-md-12\" style=\"border-bottom: 1px solid #B8B8B8\"><div class=\"content-holder h-100 component-border overflow-hidden row m-0 p-4 aling-items-center\"><ul class=\"p-0 list-style-none\"><li class=\"p-0 me-2\"><i class=\"fas fa-solid fa-newspaper fa-fw\"><\/i> REVISTA Revue des politiques sociales et familiales<\/li><li class=\"p-0\"><i class=\"fa fa-regular fa-calendar fa-fw\"><\/i> 2015<\/li><\/ul><div class=\"caption col-12 p-0 col-md-12 row m-0 align-items-center\"><div class=\"px-md-1\"><h3 class=\"small-space title-ss text-decoration-none m-0\">L\u0092accueil des enfants de 2 \u00e0 3 ans. Regards crois\u00e9s sur une cat\u00e9gorie d\u0092\u00e2ge dans diff\u00e9rents lieux d\u0092accueil collectif<\/h3><br><i class=\"fas fa-solid fa-users fa-fw me-2\"><\/i><small class=\"text-muted\"> \u2022 Pascale Garnier \u2022  Gilles Broug\u00e8re \u2022  Pablo Iv\u00e1n Rup\u00edn Guti\u00e9rrez \u2022  Sylvie Rayna \u2022  Natalia La Valle <\/small><br><p class=\"text-muted pt-3 position-relative\" style=\"z-index:2;\"><a href=\"http:\/\/dx.doi.org\/10.3406\/CAF.2015.3110\" target=\"_blank\"><i class=\"fas fa-solid fa-link fa-fw\"><\/i> http:\/\/dx.doi.org\/10.3406\/CAF.2015.3110<\/a><\/small><span class=\"caption-field-publish\"><\/span><\/div><\/div><\/div><\/div><\/div><div class=\"  circle--pattern-bottom-large col-sm-12 col-md-12 img-article\"><div class=\"holder-publish col-md-12\" style=\"border-bottom: 1px solid #B8B8B8\"><div class=\"content-holder h-100 component-border overflow-hidden row m-0 p-4 aling-items-center\"><ul class=\"p-0 list-style-none\"><li class=\"p-0 me-2\"><i class=\"fas fa-solid fa-newspaper fa-fw\"><\/i> REVISTA Revue des politiques sociales et familiales<\/li><li class=\"p-0\"><i class=\"fa fa-regular fa-calendar fa-fw\"><\/i> 2015<\/li><\/ul><div class=\"caption col-12 p-0 col-md-12 row m-0 align-items-center\"><div class=\"px-md-1\"><h3 class=\"small-space title-ss text-decoration-none m-0\">L\u0092accueil des enfants de 2 \u00e0 3 ans. Regards crois\u00e9s sur une cat\u00e9gorie d\u0092\u00e2ge dans diff\u00e9rents lieux d\u0092accueil collectif<\/h3><br><i class=\"fas fa-solid fa-users fa-fw me-2\"><\/i><small class=\"text-muted\"> \u2022 Pascale Garnier \u2022  Gilles Broug\u00e8re \u2022  Pablo Iv\u00e1n Rup\u00edn Guti\u00e9rrez \u2022  Sylvie Rayna \u2022  Natalia La Valle <\/small><br><p class=\"text-muted pt-3 position-relative\" style=\"z-index:2;\"><a href=\"http:\/\/dx.doi.org\/10.3406\/CAF.2015.3110\" target=\"_blank\"><i class=\"fas fa-solid fa-link fa-fw\"><\/i> http:\/\/dx.doi.org\/10.3406\/CAF.2015.3110<\/a><\/small><span class=\"caption-field-publish\"><\/span><\/div><\/div><\/div><\/div><\/div><div class=\"  circle--pattern-bottom-large col-sm-12 col-md-12 img-article\"><div class=\"holder-publish col-md-12\" style=\"border-bottom: 1px solid #B8B8B8\"><div class=\"content-holder h-100 component-border overflow-hidden row m-0 p-4 aling-items-center\"><ul class=\"p-0 list-style-none\"><li class=\"p-0 me-2\"><i class=\"fas fa-solid fa-newspaper fa-fw\"><\/i> REVISTA Revue internationale de l\u0092\u00e9ducation familiale<\/li><li class=\"p-0\"><i class=\"fa fa-regular fa-calendar fa-fw\"><\/i> 2012<\/li><\/ul><div class=\"caption col-12 p-0 col-md-12 row m-0 align-items-center\"><div class=\"px-md-1\"><h3 class=\"small-space title-ss text-decoration-none m-0\">Participation parentale au pr\u00e9scolaire : apprentissages et pratiques communautaires au Chili<\/h3><br><i class=\"fas fa-solid fa-users fa-fw me-2\"><\/i><small class=\"text-muted\"> \u2022 Pablo Iv\u00e1n Rup\u00edn Guti\u00e9rrez <\/small><br><p class=\"text-muted pt-3 position-relative\" style=\"z-index:2;\"><a href=\"http:\/\/dx.doi.org\/10.3917\/rief.032.0079\" target=\"_blank\"><i class=\"fas fa-solid fa-link fa-fw\"><\/i> http:\/\/dx.doi.org\/10.3917\/rief.032.0079<\/a><\/small><span class=\"caption-field-publish\"><\/span><\/div><\/div><\/div><\/div><\/div><div class=\"  circle--pattern-bottom-large col-sm-12 col-md-12 img-article\"><div class=\"holder-publish col-md-12\" style=\"border-bottom: 1px solid #B8B8B8\"><div class=\"content-holder h-100 component-border overflow-hidden row m-0 p-4 aling-items-center\"><ul class=\"p-0 list-style-none\"><li class=\"p-0 me-2\"><i class=\"fas fa-solid fa-newspaper fa-fw\"><\/i> REVISTA Revue internationale de l\u0092\u00e9ducation familiale<\/li><li class=\"p-0\"><i class=\"fa fa-regular fa-calendar fa-fw\"><\/i> 2012<\/li><\/ul><div class=\"caption col-12 p-0 col-md-12 row m-0 align-items-center\"><div class=\"px-md-1\"><h3 class=\"small-space title-ss text-decoration-none m-0\">Participation parentale au pr\u00e9scolaire : apprentissages et pratiques communautaires au Chili<\/h3><br><i class=\"fas fa-solid fa-users fa-fw me-2\"><\/i><small class=\"text-muted\"> \u2022 Pablo Iv\u00e1n Rup\u00edn Guti\u00e9rrez <\/small><br><p class=\"text-muted pt-3 position-relative\" style=\"z-index:2;\"><a href=\"http:\/\/dx.doi.org\/10.3917\/rief.032.0079\" target=\"_blank\"><i class=\"fas fa-solid fa-link fa-fw\"><\/i> http:\/\/dx.doi.org\/10.3917\/rief.032.0079<\/a><\/small><span class=\"caption-field-publish\"><\/span><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div>[\/vc_tta_section][vc_tta_section title=&#8221;Proyectos&#8221; tab_id=&#8221;proyectos&#8221;]<link rel=\"stylesheet\" id=\"font-awesome-css\" href=\"https:\/\/cdnjs.cloudflare.com\/ajax\/libs\/font-awesome\/6.5.1\/css\/all.min.css\" type=\"text\/css\" media=\"all\"><div class=\"row m-0 p-0\"><div class=\"col-12 col-md-9 pt-5 pt-md-0 px-md-0 \"><\/div><\/div><div class=\"content-holder row m-0 p-0 aling-items-center pt-5 pb-5 \"><div class=\"row  large--swipper-content p-0 \"><div class=\"\"><div class=\"  circle--pattern-bottom-large col-sm-12 col-md-12 img-article\"><div class=\"holder-publish col-md-12\" style=\"border-bottom: 1px solid #48A2F9\"><div class=\"content-holder h-100 component-border overflow-hidden row m-0 p-4 aling-items-center\"><ul class=\"p-0 list-style-none\"><li class=\"p-0 ms-1\"><i class=\"fa fa-regular fa-calendar fa-fw ms-1\"><\/i>Septiembre 2024<\/li><\/ul><div class=\"caption col-12 p-0 col-md-12 row m-0 align-items-center\"><div class=\"px-md-1\"><small class=\"badge rounded-pill fw-semibold\" style=\"background-color:#48A2F9 !important; color:#FFF\">En Ejecuci\u00f3n<\/small><small class=\"ms-2 badge rounded-pill fw-semibold\" style=\"background-color:#F0F1F3 !important; color:#797979\"><i class=\"fa fa-solid fa-lg fa-money-check-dollar fa-fw me-1\"><\/i>International Centre for Antimicrobial Resistance Solutions (ICARS)<\/small>\n                            <div class=\"accordion accordion-flush\" id=\"36993\">\n                                <div class=\"accordion-item\">\n                                    <h3 class=\"my-0 small-space pt-2 title-ss text-decoration-none accordion-header\">\n                                        <a role=\"button\" class=\"bg-transparent p-0\" href=\"\">\n                                            <i class=\"fas fa-solid fa-link fa-fw me-2\"><\/i>\n                                            Surveillance, alert, and response system (SVAR) for the use of antimicrobials in Chilean salmon farming\n                                        <\/a><\/h3>\n                                    <div id=\"collapse-36993\" class=\"accordion-collapse collapse\" data-bs-parent=\"#36993\">\n                                        <div class=\"accordion-body p-0 pt-4 pb-4\">\n                                            [vc_section el_class=\"container mx-auto align-items-center circle--pattern\" css=\".vc_custom_1648956589196{padding-top: 3rem !important;}\"][vc_row el_class=\"pb-5\"][vc_column][vc_wp_custommenu nav_menu=\"6\"][uoh_breadcrumb_component automatic_breadcrumb=\"true\"][uoh_title_component title_dropdown=\"big\" title_decorator=\"true\"]{{title}}[\/uoh_title_component][vc_column_text css=\"\"]The use of antimicrobials (AMU) in the salmon farming industry in Chile is concentrated in the sea fattening phase of the production cycle. In 2022, 91% of the AMU in fattening farms was for treatment of Piscirickettsia salmonis (Sernapesca, 2023), the main disease-causing pathogen affecting farmed salmon in Chile (Rozas and Enriquez, 2014).\r\n\r\nTo control P. salmonis, a series of preventive strategies have been adopted. Nevertheless, the incidence of P. salmonis remains high; resulting in high mortality rates (Jakob et al., 2014) and extensive AMU. The use of antimicrobials is exacerbated by current management practices in salmon farms as well as a lack of standardization in treatment guidelines and practices between veterinarians and companies (e.g. treatment of all or selected cages, dosage, etc.), but also because of limited consolidation, communication and use of available AMU data.\r\n\r\nThe aim of this project is to reduce antimicrobial consumption in salmon farming in Los Lagos and Aysen regions where P. salmonis is a challenge and improve science-based governance of AMU in the salmon farming sector through a surveillance, alert and response system (SVARS). The project will be implemented in two phases. Phase one will focus on increasing the knowledge of AMU drivers by developing a catalog of practices and factors that impact the use of antimicrobials and conduct a cost-effectiveness analysis to assess the more cost efficient alternative methods to AMU practices. The catalog will be compiled in a format that can be used to implement improvements on high AMU farms. Different AMU metrics will be reviewed and selected to differentiate farms with low, medium and high AMU. In addition, the legislative requirements to develop and sustain a surveillance, alert and response system (SVARS) to reduce AMU in Chilean salmon farming will be reviewed. Finally, the infrastructural and operational requirements for the platform will be assessed and the design of the platform will be completed, integrating geospatial and health information.\r\n\r\nIn phase two, the SVARS will categorize the farms based on their AMU levels. The high use farms will be recruited to a Randomized Controlled Trial where intervention farms will implement practices and methods from the catalog created in phase one to reduce AMU. The outcomes and the effectiveness of the SVARS will be quantitatively and qualitatively assessed. Finally, results and outcomes of establishing and implementing the SVARS will be shared with relevant stakeholders in Chile, to low-and middle-income countries in the region and beyond, e.g. through workshops and education training programs in order to disseminate the results.[\/vc_column_text][\/vc_column][\/vc_row][\/vc_section][vc_section css=\".vc_custom_1649209804184{background-color: #f6faff !important;}\" el_class=\"p-md-0 pt-md-5\"][vc_row el_class=\"container mx-auto align-items-center p-md-0 pt-5\"][vc_column el_class=\"p-0\"][\/vc_column][\/vc_row][\/vc_section][vc_section css=\".vc_custom_1649210787516{background-color: #f6faff !important;}\" el_class=\"p-md-0 pt-md-5 pb-md-5\"][vc_row el_class=\"container mx-auto align-items-center\"][vc_column][\/vc_column][\/vc_row][\/vc_section]\n                                        <\/div>\n                                    <\/div>\n                                <\/div>\n                            <\/div><div class=\"mt-3\"><i class=\"fas fa-solid fa-user-tag fa-fw me-2\"><\/i><small class=\"text-muted\">Investigador\/a Responsable<\/small><\/div><span class=\"caption-field-publish\"><\/span><\/div><\/div><\/div><\/div><\/div><div class=\"  circle--pattern-bottom-large col-sm-12 col-md-12 img-article\"><div class=\"holder-publish col-md-12\" style=\"border-bottom: 1px solid #48A2F9\"><div class=\"content-holder h-100 component-border overflow-hidden row m-0 p-4 aling-items-center\"><ul class=\"p-0 list-style-none\"><li class=\"p-0 ms-1 me-2\"><i class=\"fa fa-solid fa-id-card-clip fa-fw\"><\/i> 24I10188<\/li><li class=\"p-0 ms-1\"><i class=\"fa fa-regular fa-calendar fa-fw ms-1\"><\/i>Junio 2024 - Junio 2026<\/li><\/ul><div class=\"caption col-12 p-0 col-md-12 row m-0 align-items-center\"><div class=\"px-md-1\"><small class=\"badge rounded-pill fw-semibold\" style=\"background-color:#48A2F9 !important; color:#FFF\">En Ejecuci\u00f3n<\/small><small class=\"ms-2 badge rounded-pill fw-semibold\" style=\"background-color:#F0F1F3 !important; color:#797979\"><i class=\"fa fa-solid fa-lg fa-money-check-dollar fa-fw me-1\"><\/i>Agencia Nacional de Investigaci\u00f3n y Desarrollo - ANID<\/small>\n                            <div class=\"accordion accordion-flush\" id=\"36995\">\n                                <div class=\"accordion-item\">\n                                    <h3 class=\"my-0 small-space pt-2 title-ss text-decoration-none accordion-header\">\n                                        <a role=\"button\" class=\"bg-transparent p-0\" href=\"\">\n                                            <i class=\"fas fa-solid fa-link fa-fw me-2\"><\/i>\n                                            Herramienta molecular para el monitoreo de la sensibilidad farmacol\u00f3gica de productos antiparasitarios contra el piojo de mar en la industria salmonera\n                                        <\/a><\/h3>\n                                    <div id=\"collapse-36995\" class=\"accordion-collapse collapse\" data-bs-parent=\"#36995\">\n                                        <div class=\"accordion-body p-0 pt-4 pb-4\">\n                                            [vc_section el_class=\"container mx-auto align-items-center circle--pattern\" css=\".vc_custom_1648956589196{padding-top: 3rem !important;}\"][vc_row el_class=\"pb-5\"][vc_column][vc_wp_custommenu nav_menu=\"6\"][uoh_breadcrumb_component automatic_breadcrumb=\"true\"][uoh_title_component title_dropdown=\"big\" title_decorator=\"true\"]{{title}}[\/uoh_title_component][vc_column_text css=\"\"]Objetivo General\r\nDesarrollar un kit de qPCR que permita evaluar con precisi\u00f3n la sensibilidad farmacol\u00f3gica de C.\r\nrogercresseyi a tratamientos como inhibidores de quitina mediante asociaci\u00f3n estad\u00edstica entre\r\nfrecuencia de marcadores gen\u00f3micos y eficacia de tratamientos en campo.\r\n\r\nObjetivos Espec\u00edficos\r\n1. Validar estad\u00edsticamente la relaci\u00f3n entre las variantes gen\u00f3micas detectadas por el kit de\r\nqPCR y la resistencia a tratamientos con inhibidores de quitina.\r\n2. Establecer un protocolo de buenas pr\u00e1cticas de laboratorio para la correcta aplicaci\u00f3n del\r\nkit de qPCR.\r\n3. Implementar capacitaciones para laboratorios y culminar con la certificaci\u00f3n de aquellos\r\naptos para aplicar la t\u00e9cnica con eficacia.[\/vc_column_text][\/vc_column][\/vc_row][\/vc_section][vc_section css=\".vc_custom_1649209804184{background-color: #f6faff !important;}\" el_class=\"p-md-0 pt-md-5\"][vc_row el_class=\"container mx-auto align-items-center p-md-0 pt-5\"][vc_column el_class=\"p-0\"][\/vc_column][\/vc_row][\/vc_section][vc_section css=\".vc_custom_1649210787516{background-color: #f6faff !important;}\" el_class=\"p-md-0 pt-md-5 pb-md-5\"][vc_row el_class=\"container mx-auto align-items-center\"][vc_column][\/vc_column][\/vc_row][\/vc_section]\n                                        <\/div>\n                                    <\/div>\n                                <\/div>\n                            <\/div><div class=\"mt-3\"><i class=\"fas fa-solid fa-user-tag fa-fw me-2\"><\/i><small class=\"text-muted\">Co-Investigador\/a<\/small><\/div><span class=\"caption-field-publish\"><\/span><\/div><\/div><\/div><\/div><\/div><div class=\"  circle--pattern-bottom-large col-sm-12 col-md-12 img-article\"><div class=\"holder-publish col-md-12\" style=\"border-bottom: 1px solid #EFB956\"><div class=\"content-holder h-100 component-border overflow-hidden row m-0 p-4 aling-items-center\"><ul class=\"p-0 list-style-none\"><li class=\"p-0 ms-1\"><i class=\"fa fa-regular fa-calendar fa-fw ms-1\"><\/i>Abril 2024 - Marzo 2027<\/li><\/ul><div class=\"caption col-12 p-0 col-md-12 row m-0 align-items-center\"><div class=\"px-md-1\"><small class=\"badge rounded-pill fw-semibold\" style=\"background-color:#EFB956 !important; color:#FFF\">Adjudicado<\/small><small class=\"ms-2 badge rounded-pill fw-semibold\" style=\"background-color:#F0F1F3 !important; color:#797979\"><i class=\"fa fa-solid fa-lg fa-money-check-dollar fa-fw me-1\"><\/i>Agencia Nacional de Investigaci\u00f3n y Desarrollo - ANID<\/small>\n                            <div class=\"accordion accordion-flush\" id=\"37017\">\n                                <div class=\"accordion-item\">\n                                    <h3 class=\"my-0 small-space pt-2 title-ss text-decoration-none accordion-header\">\n                                        <a role=\"button\" class=\"bg-transparent p-0\" href=\"\">\n                                            <i class=\"fas fa-solid fa-link fa-fw me-2\"><\/i>\n                                            A Biopsychosocial Approach for Frailty Intervention: Uncovering a Circulating microRNA Biomarker Panel Using an Omics-Based Machine Learning Approach\n                                        <\/a><\/h3>\n                                    <div id=\"collapse-37017\" class=\"accordion-collapse collapse\" data-bs-parent=\"#37017\">\n                                        <div class=\"accordion-body p-0 pt-4 pb-4\">\n                                            [vc_section el_class=\"container mx-auto align-items-center circle--pattern\" css=\".vc_custom_1648956589196{padding-top: 3rem !important;}\"][vc_row el_class=\"pb-5\"][vc_column][vc_wp_custommenu nav_menu=\"6\"][uoh_breadcrumb_component automatic_breadcrumb=\"true\"][uoh_title_component title_dropdown=\"big\" title_decorator=\"true\"]{{title}}[\/uoh_title_component][vc_column_text css=\"\"]Frailty is increasingly becoming an important public health challenge worldwide because it is associated with older age, and with adverse outcomes such as reduced quality of life, increased mortality rates, hospitalizations, falls, depression, and dementia. Frailty is defined as dynamic state affecting an individual who experiences losses in one or more domains of human functioning (physical, psychological, social) that are caused by the influence of a range of variables, and which increases the risk of adverse outcomes. This more integral conceptual definition promotes the collaboration of scientists, social and behavioral professionals as well as clinicians from diverse specialties. In this proposal an interdisciplinary group (Biochemistry, Geriatric, Occupational Therapist, Kinesiologist, social worker, bioengineer, statistician among others) aims to evaluate frailty in Chile with a biopsychosocial approach with the final purpose to identify and manage frailty while taking into consideration all the dimensions. Additionally, we aim to design a multidomain personalized person-base intervention for a healthy aging that can uncover a circulating microRNA biomarker panel that can allow an early-detection of frailty, leading to a new multidimensional geriatric assessment. We propose the following hypothesis:  A personalized multidimensional training program reduces the frailty prevalence, increasing adherence and participation in the program among community-living older adults. This intervention will be paralleled by a distinctive miRNA profile reflecting the multiple domains of frailty, as well as improvements in diverse psychosocial traits.[\/vc_column_text][\/vc_column][\/vc_row][\/vc_section][vc_section css=\".vc_custom_1649209804184{background-color: #f6faff !important;}\" el_class=\"p-md-0 pt-md-5\"][vc_row el_class=\"container mx-auto align-items-center p-md-0 pt-5\"][vc_column el_class=\"p-0\"][\/vc_column][\/vc_row][\/vc_section][vc_section css=\".vc_custom_1649210787516{background-color: #f6faff !important;}\" el_class=\"p-md-0 pt-md-5 pb-md-5\"][vc_row el_class=\"container mx-auto align-items-center\"][vc_column][\/vc_column][\/vc_row][\/vc_section]\n                                        <\/div>\n                                    <\/div>\n                                <\/div>\n                            <\/div><div class=\"mt-3\"><i class=\"fas fa-solid fa-user-tag fa-fw me-2\"><\/i><small class=\"text-muted\">Investigador\/a Responsable<\/small><\/div><span class=\"caption-field-publish\"><\/span><\/div><\/div><\/div><\/div><\/div><div class=\"  circle--pattern-bottom-large col-sm-12 col-md-12 img-article\"><div class=\"holder-publish col-md-12\" style=\"border-bottom: 1px solid #35DB54\"><div class=\"content-holder h-100 component-border overflow-hidden row m-0 p-4 aling-items-center\"><ul class=\"p-0 list-style-none\"><li class=\"p-0 ms-1 me-2\"><i class=\"fa fa-solid fa-id-card-clip fa-fw\"><\/i> FOVI230047<\/li><li class=\"p-0 ms-1\"><i class=\"fa fa-regular fa-calendar fa-fw ms-1\"><\/i>Enero 2024 - Diciembre 2024<\/li><\/ul><div class=\"caption col-12 p-0 col-md-12 row m-0 align-items-center\"><div class=\"px-md-1\"><small class=\"badge rounded-pill fw-semibold\" style=\"background-color:#35DB54 !important; color:#FFF\">Finalizado<\/small><small class=\"ms-2 badge rounded-pill fw-semibold\" style=\"background-color:#F0F1F3 !important; color:#797979\"><i class=\"fa fa-solid fa-lg fa-money-check-dollar fa-fw me-1\"><\/i>Agencia Nacional de Investigaci\u00f3n y Desarrollo - ANID<\/small>\n                            <div class=\"accordion accordion-flush\" id=\"36989\">\n                                <div class=\"accordion-item\">\n                                    <h3 class=\"my-0 small-space pt-2 title-ss text-decoration-none accordion-header\">\n                                        <a role=\"button\" class=\"bg-transparent p-0\" href=\"\">\n                                            <i class=\"fas fa-solid fa-link fa-fw me-2\"><\/i>\n                                            Vinculaci\u00f3n internacional para la evaluaci\u00f3n de la capacidad centinela de moluscos bivalvos filtradores en el monitoreo de contaminantes emergentes en \u00e1reas costeras marinas\n                                        <\/a><\/h3>\n                                    <div id=\"collapse-36989\" class=\"accordion-collapse collapse\" data-bs-parent=\"#36989\">\n                                        <div class=\"accordion-body p-0 pt-4 pb-4\">\n                                            [vc_section el_class=\"container mx-auto align-items-center circle--pattern\" css=\".vc_custom_1648956589196{padding-top: 3rem !important;}\"][vc_row el_class=\"pb-5\"][vc_column][vc_wp_custommenu nav_menu=\"6\"][uoh_breadcrumb_component automatic_breadcrumb=\"true\"][uoh_title_component title_dropdown=\"big\" title_decorator=\"true\"]{{title}}[\/uoh_title_component][vc_column_text css=\"\"]Vinculaci\u00f3n internacional para la evaluaci\u00f3n de la capacidad centinela de moluscos bivalvos filtradores en el monitoreo de contaminantes emergentes en \u00e1reas costeras marinas[\/vc_column_text][\/vc_column][\/vc_row][\/vc_section][vc_section css=\".vc_custom_1649209804184{background-color: #f6faff !important;}\" el_class=\"p-md-0 pt-md-5\"][vc_row el_class=\"container mx-auto align-items-center p-md-0 pt-5\"][vc_column el_class=\"p-0\"][\/vc_column][\/vc_row][\/vc_section][vc_section css=\".vc_custom_1649210787516{background-color: #f6faff !important;}\" el_class=\"p-md-0 pt-md-5 pb-md-5\"][vc_row el_class=\"container mx-auto align-items-center\"][vc_column][\/vc_column][\/vc_row][\/vc_section]\n                                        <\/div>\n                                    <\/div>\n                                <\/div>\n                            <\/div><div class=\"mt-3\"><i class=\"fas fa-solid fa-user-tag fa-fw me-2\"><\/i><small class=\"text-muted\">Co-Investigador\/a<\/small><\/div><span class=\"caption-field-publish\"><\/span><\/div><\/div><\/div><\/div><\/div><div class=\"  circle--pattern-bottom-large col-sm-12 col-md-12 img-article\"><div class=\"holder-publish col-md-12\" style=\"border-bottom: 1px solid #48A2F9\"><div class=\"content-holder h-100 component-border overflow-hidden row m-0 p-4 aling-items-center\"><ul class=\"p-0 list-style-none\"><li class=\"p-0 ms-1\"><i class=\"fa fa-regular fa-calendar fa-fw ms-1\"><\/i>Enero 2024 - Diciembre 2025<\/li><\/ul><div class=\"caption col-12 p-0 col-md-12 row m-0 align-items-center\"><div class=\"px-md-1\"><small class=\"badge rounded-pill fw-semibold\" style=\"background-color:#48A2F9 !important; color:#FFF\">En Ejecuci\u00f3n<\/small><small class=\"ms-2 badge rounded-pill fw-semibold\" style=\"background-color:#F0F1F3 !important; color:#797979\"><i class=\"fa fa-solid fa-lg fa-money-check-dollar fa-fw me-1\"><\/i>Universidad de O'Higgins<\/small>\n                            <div class=\"accordion accordion-flush\" id=\"37026\">\n                                <div class=\"accordion-item\">\n                                    <h3 class=\"my-0 small-space pt-2 title-ss text-decoration-none accordion-header\">\n                                        <a role=\"button\" class=\"bg-transparent p-0\" href=\"\">\n                                            <i class=\"fas fa-solid fa-link fa-fw me-2\"><\/i>\n                                            An\u00e1lisis multi\u00f3mico de redes reguladoras post-transcripcionales microARN- ARNm en el m\u00fasculo esquel\u00e9tico humano envejecido.\n                                        <\/a><\/h3>\n                                    <div id=\"collapse-37026\" class=\"accordion-collapse collapse\" data-bs-parent=\"#37026\">\n                                        <div class=\"accordion-body p-0 pt-4 pb-4\">\n                                            [vc_section el_class=\"container mx-auto align-items-center circle--pattern\" css=\".vc_custom_1648956589196{padding-top: 3rem !important;}\"][vc_row el_class=\"pb-5\"][vc_column][vc_wp_custommenu nav_menu=\"6\"][uoh_breadcrumb_component automatic_breadcrumb=\"true\"][uoh_title_component title_dropdown=\"big\" title_decorator=\"true\"]{{title}}[\/uoh_title_component][vc_column_text css=\"\"]Durante las \u00faltimas d\u00e9cadas, la expectativa de vida promedio ha aumentado dram\u00e1ticamente, mientras\r\nque la salud no ha aumentado proporcionalmente. Para Chile se espera que para el 2050 el n\u00famero de\r\nadultos mayores superar\u00e1 el 30% de la poblaci\u00f3n con un incremento del 109% respecto al 2015,\r\nsuperando el 75% proyectado para la poblaci\u00f3n mundial. Entender el proceso de envejecimeinto y\r\nencontrar marcadores biol\u00f3gicos con capacidad diagn\u00f3stica y pron\u00f3stica, permitir\u00e1 promover estrategias\r\npara aumentar el n\u00famero de a\u00f1os de vida saludable, disminuyendo los gastos en salud asociado al\r\nenvejecimiento.\r\nVarios estudios han permitido avanzar y entender los mecanismos moleculares de p\u00e9rdidad de funci\u00f3n\r\nmuscular durante el evenjecimiento, m\u00e1s conocida como sarcopenia. Sin embargo, la complejidad del\r\nproceso y el insuficiente conocimiento de los mecanismos subjacentes dificultan el dise\u00f1o de estrategias\r\nterap\u00e9uticas eficaces. Hasta el momento, la actividad f\u00edsica y el ejercicio siguen siendo la estrategia m\u00e1s\r\neficaz para previnir y tratar la sarcopenia. Por lo cual, identificar nuevos biomarcadores musculares en\r\ncombinaci\u00f3n con marcadores cl\u00ednicos bien establecidos de par\u00e1metros f\u00edsicos y funcionales, fortalecer\u00eda\r\nla actual evaluaci\u00f3n geri\u00e1trica, al utilizar un enfoque interdiciplinario.\r\nLos microRNA (miRNA, 18\u009625 nt de largo) han ganado inter\u00e9s debido a que son mol\u00e9culas altamente\r\nconservadas en todas las especies, y act\u00faan como reguladores positivos y\/o negativos de la expresi\u00f3n\r\ng\u00e9nica. Entender la relaci\u00f3n reguladora directa entre los miARN y el ARN mensajero (mRNA) desempe\u00f1a\r\nen el m\u00fasculo esquel\u00e9tica es fundamentaltanto para el proceso de transcripci\u00f3n del ARNm y traducci\u00f3n\r\nde prote\u00ednas como para entender el deterioro de la funci\u00f3n muscular. Sin embargo, la regulaci\u00f3n de la\r\nred post-transcripcional miARN-ARNm y los mecanismos gen\u00e9ticos involucrados en el proceso de\r\nenvejecimiento del m\u00fasculo esquel\u00e9tico humano est\u00e1n lejos de ser elucidados.\r\nEn el presente estudio, nuestro objetivo es explorar e integrar coperfiles emparejados de miARN y ARNm\r\ndurante la p\u00e9rdida de funci\u00f3n muscular producidad durante el envejecimeinto en personas mayores. Este\r\nan\u00e1lisis integral permitir\u00e1 la identificaci\u00f3n de nuevos blancos de miARN y estrategias reguladoras que\r\ncontrolan la expresi\u00f3n g\u00e9nica en la p\u00e9rdidad de funci\u00f3n del m\u00fasculo esquel\u00e9tico y c\u00f3mo \u00e9stas son\r\nmodificadas por el entrenamiento de fuerza.\r\nSe hipotetiza que existen redes de regulaci\u00f3n post-transcripcional miRNA\/mRNA que se expresan de\r\nmanera diferencial en el m\u00fasculo esquel\u00e9tico de personas j\u00f3venes y personas mayores, que estar\u00edan\r\nasociadas con cambios en la funci\u00f3n muscular durante el envejecimiento. Adem\u00e1s, el entrenamiento de\r\nfuerza modifica estas redes de regulaci\u00f3n, lo que podr\u00eda contribuir a la mejora de la funci\u00f3n muscular y la\r\nprevenci\u00f3n o atenuaci\u00f3n de la sarcopenia.\r\nObjetivos generales\r\n- Identificar las redes de regulaci\u00f3n post-transcripcional miRNA\/mRNA involucradas en la\r\np\u00e9rdida de funci\u00f3n musclular en personas mayores que son moduladas por un entrenamiento\r\nde fuerza, para proponer nuevos biomarcadores de funci\u00f3n muscular durante el\r\nenvejecimeinto que se correlacionan con par\u00e1metros cl\u00ednicos\/funcionales.\r\nObjetivos espec\u00edficos\r\n1. Determinar las redes de regulaci\u00f3n post-transcripcional miRNA\/mRNA que se expresan\r\ndiferencialmente en el m\u00fasculo esquel\u00e9tico de personas j\u00f3venes y personas mayores.\r\n2. Identificar las redes de regulaci\u00f3n post-transcripcional miRNA\/mRNA que se modifican\r\ndespu\u00e9s de 12 semanas de entrenamiento de fuerza en personas mayores\r\n3. Correlacionar las redes miRNA\/mRNA identificadas con par\u00e1metros bioqu\u00edmicos, f\u00edsicos y\r\nfuncionales de funci\u00f3n muscular, antes y despu\u00e9s de 12 semanas de entrenamiento de\r\nfuerza en personas mayores\r\nEste proyecto busca Identificar nuevos biomarcadores de funci\u00f3n muscular durante el envejecimiento,\r\npodr\u00edan ser utilizados en futuros estudios y en la pr\u00e1ctica cl\u00ednica para evaluar la salud muscular en\r\npersonas mayores. Adem\u00e1s, de contribuir a una mejor comprensi\u00f3n de los mecanismos moleculares que\r\nsubyacen a la p\u00e9rdida de masa muscular en el envejecimiento y c\u00f3mo la intervenci\u00f3n del entrenamiento\r\nde fuerza puede modificar esos mecanismos. Finalmente, el uso de tecnolog\u00edas avanzadas de\r\nsecuenciaci\u00f3n (mARN y miARN) y bioinform\u00e1tica permitir\u00e1 impulsar el desarrollo y la mejora de t\u00e9cnicas\r\nde secuenciaci\u00f3n y an\u00e1lisis de datos en el campo de la gen\u00f3mica y la transcript\u00f3mica en el \u00e1rea del\r\nenvejecimiento, como tambi\u00e9n, promover la colaboraci\u00f3n a nivel nacional e internacional a trav\u00e9s de las\r\nbases de datos y recursos bioinform\u00e1ticos generados que estar\u00e1n a disposici\u00f3n de investigadores del \u00e1rea.[\/vc_column_text][\/vc_column][\/vc_row][\/vc_section][vc_section css=\".vc_custom_1649209804184{background-color: #f6faff !important;}\" el_class=\"p-md-0 pt-md-5\"][vc_row el_class=\"container mx-auto align-items-center p-md-0 pt-5\"][vc_column el_class=\"p-0\"][\/vc_column][\/vc_row][\/vc_section][vc_section css=\".vc_custom_1649210787516{background-color: #f6faff !important;}\" el_class=\"p-md-0 pt-md-5 pb-md-5\"][vc_row el_class=\"container mx-auto align-items-center\"][vc_column][\/vc_column][\/vc_row][\/vc_section]\n                                        <\/div>\n                                    <\/div>\n                                <\/div>\n                            <\/div><div class=\"mt-3\"><i class=\"fas fa-solid fa-user-tag fa-fw me-2\"><\/i><small class=\"text-muted\">Investigador\/a Responsable<\/small><\/div><span class=\"caption-field-publish\"><\/span><\/div><\/div><\/div><\/div><\/div><div class=\"  circle--pattern-bottom-large col-sm-12 col-md-12 img-article\"><div class=\"holder-publish col-md-12\" style=\"border-bottom: 1px solid #EFB956\"><div class=\"content-holder h-100 component-border overflow-hidden row m-0 p-4 aling-items-center\"><ul class=\"p-0 list-style-none\"><li class=\"p-0 ms-1 me-2\"><i class=\"fa fa-solid fa-id-card-clip fa-fw\"><\/i> 23CVC-245806<\/li><li class=\"p-0 ms-1\"><i class=\"fa fa-regular fa-calendar fa-fw ms-1\"><\/i>Octubre 2023 - Diciembre 2026<\/li><\/ul><div class=\"caption col-12 p-0 col-md-12 row m-0 align-items-center\"><div class=\"px-md-1\"><small class=\"badge rounded-pill fw-semibold\" style=\"background-color:#EFB956 !important; color:#FFF\">Adjudicado<\/small><small class=\"ms-2 badge rounded-pill fw-semibold\" style=\"background-color:#F0F1F3 !important; color:#797979\"><i class=\"fa fa-solid fa-lg fa-money-check-dollar fa-fw me-1\"><\/i>Corporaci\u00f3n de Fomento de la Producci\u00f3n - CORFO<\/small>\n                            <div class=\"accordion accordion-flush\" id=\"37021\">\n                                <div class=\"accordion-item\">\n                                    <h3 class=\"my-0 small-space pt-2 title-ss text-decoration-none accordion-header\">\n                                        <a role=\"button\" class=\"bg-transparent p-0\" href=\"\">\n                                            <i class=\"fas fa-solid fa-link fa-fw me-2\"><\/i>\n                                            Strong-Bee: Gel multi-ingredientes formulado en base a compuestos naturales, especialmente desarrollado para favorecer la recuperaci\u00f3n muscular y el rendimiento de deportistas\n                                        <\/a><\/h3>\n                                    <div id=\"collapse-37021\" class=\"accordion-collapse collapse\" data-bs-parent=\"#37021\">\n                                        <div class=\"accordion-body p-0 pt-4 pb-4\">\n                                            [vc_section el_class=\"container mx-auto align-items-center circle--pattern\" css=\".vc_custom_1648956589196{padding-top: 3rem !important;}\"][vc_row el_class=\"pb-5\"][vc_column][vc_wp_custommenu nav_menu=\"6\"][uoh_breadcrumb_component automatic_breadcrumb=\"true\"][uoh_title_component title_dropdown=\"big\" title_decorator=\"true\"]{{title}}[\/uoh_title_component][vc_column_text css=\"\"]Desarrollar y validar mediante ensayos in vivo un gel energ\u00e9tico para deportistas de alto rendimiento, formulado en\r\nbase a miel y extractos naturales, para ser utilizado como potenciador del rendimiento deportivo y la recuperaci\u00f3n\r\nmuscular post ejercicio. Los principales objetivos son: 1) Formular el gel energ\u00e9tico en base a los requerimientos\r\nnutricionales espec\u00ed&#1048789;cos de deportistas de alto rendimiento, caracteriz\u00e1ndolo en t\u00e9rminos nutricionales, capacidad\r\nantioxidante y ausencia de sustancias no deseadas. 2)Evaluar la tolerabilidad in vivo del producto en t\u00e9rminos de\r\npalatabilidad y efectos gastrointestinales. 3)Dise\u00f1ar e implementar el proceso mezclamiento y envasado para escalar\r\nla producci\u00f3n. 4)Cuanti&#1048789;car los efectos del producto desarrollado respecto del aporte sobre el rendimiento deportivo,\r\nla recuperaci\u00f3n muscular post ejercicio y s\u00edntomas de malestar gastrointestinal. y 5) Fortalecer el modelo de negocios.[\/vc_column_text][\/vc_column][\/vc_row][\/vc_section][vc_section css=\".vc_custom_1649209804184{background-color: #f6faff !important;}\" el_class=\"p-md-0 pt-md-5\"][vc_row el_class=\"container mx-auto align-items-center p-md-0 pt-5\"][vc_column el_class=\"p-0\"][\/vc_column][\/vc_row][\/vc_section][vc_section css=\".vc_custom_1649210787516{background-color: #f6faff !important;}\" el_class=\"p-md-0 pt-md-5 pb-md-5\"][vc_row el_class=\"container mx-auto align-items-center\"][vc_column][\/vc_column][\/vc_row][\/vc_section]\n                                        <\/div>\n                                    <\/div>\n                                <\/div>\n                            <\/div><div class=\"mt-3\"><i class=\"fas fa-solid fa-user-tag fa-fw me-2\"><\/i><small class=\"text-muted\">Co-Investigador\/a<\/small><\/div><span class=\"caption-field-publish\"><\/span><\/div><\/div><\/div><\/div><\/div><div class=\"  circle--pattern-bottom-large col-sm-12 col-md-12 img-article\"><div class=\"holder-publish col-md-12\" style=\"border-bottom: 1px solid #48A2F9\"><div class=\"content-holder h-100 component-border overflow-hidden row m-0 p-4 aling-items-center\"><ul class=\"p-0 list-style-none\"><li class=\"p-0 ms-1\"><i class=\"fa fa-regular fa-calendar fa-fw ms-1\"><\/i>Febrero 2023 - Febrero 2024<\/li><\/ul><div class=\"caption col-12 p-0 col-md-12 row m-0 align-items-center\"><div class=\"px-md-1\"><small class=\"badge rounded-pill fw-semibold\" style=\"background-color:#48A2F9 !important; color:#FFF\">En Ejecuci\u00f3n<\/small><small class=\"ms-2 badge rounded-pill fw-semibold\" style=\"background-color:#F0F1F3 !important; color:#797979\"><i class=\"fa fa-solid fa-lg fa-money-check-dollar fa-fw me-1\"><\/i>Sociedad Chilena de Nutrici\u00f3n<\/small>\n                            <div class=\"accordion accordion-flush\" id=\"37013\">\n                                <div class=\"accordion-item\">\n                                    <h3 class=\"my-0 small-space pt-2 title-ss text-decoration-none accordion-header\">\n                                        <a role=\"button\" class=\"bg-transparent p-0\" href=\"\">\n                                            <i class=\"fas fa-solid fa-link fa-fw me-2\"><\/i>\n                                            No Whey: L\u00e1cteos altos en prote\u00edna y ejercicio de resistencia para la mejora de la composici\u00f3n corporal y funci\u00f3n muscular de personas mayores.\n                                        <\/a><\/h3>\n                                    <div id=\"collapse-37013\" class=\"accordion-collapse collapse\" data-bs-parent=\"#37013\">\n                                        <div class=\"accordion-body p-0 pt-4 pb-4\">\n                                            [vc_section el_class=\"container mx-auto align-items-center circle--pattern\" css=\".vc_custom_1648956589196{padding-top: 3rem !important;}\"][vc_row el_class=\"pb-5\"][vc_column][vc_wp_custommenu nav_menu=\"6\"][uoh_breadcrumb_component automatic_breadcrumb=\"true\"][uoh_title_component title_dropdown=\"big\" title_decorator=\"true\"]{{title}}[\/uoh_title_component][vc_column_text css=\"\"]La suplementaci\u00f3n con prote\u00ednas es una de las principales recomendaciones ante la practica regular de ejercicio f\u00edsico de resistencia (RT). En personas mayores, la necesidad de prote\u00edna se incrementa particularmente ante cambios fisiol\u00f3gicos y fisiopatol\u00f3gicos los que se asocian con la p\u00e9rdida de la funci\u00f3n y tejido muscular, por lo que su ingesta se hace de mayor relevancia en esta poblaci\u00f3n. Los l\u00e1cteos fermentados como el yogur, y en especial los con un contenido extra de prote\u00edna, han aumentado su popularidad y consumo en el mercado nacional. Su composici\u00f3n nutricional resulta de particular inter\u00e9s, dado su perfil de amino\u00e1cidos y en particular su alto contenido de Leucina, el que podr\u00eda compararse con los cl\u00e1sico suplementos de prote\u00edna recomendados para la ganancia y recuperaci\u00f3n muscular. Objetivo: Analizar el efecto en la composici\u00f3n corporal, perfil lip\u00eddico, condici\u00f3n fisica y funcionalidad muscular inducidas por ingesta de yogures altos en prote\u00edna versus prote\u00edna Whey junto un programa de resistencia muscular en personas mayores Hip\u00f3tesis: La ingesta de yogures altos en prote\u00edna conllevar\u00e1 a iguales o mayores ganancias de masa muscular, condici\u00f3n fisica y funcionalidad que las obtenidas con la ingesta de prote\u00ednas Whey en conjunto a un entrenamiento de resistencia en personas mayores. Metodolog\u00eda: Se reclutar\u00e1n 16 personas mayores (60-75 a\u00f1os), sanas y sin intolerancia a la lactosa para llevar a cabo 8 semanas de entrenamiento de resistencia (RT) muscular 3 veces por semana, los que de forma aleatoria ser\u00e1n suplementados con yogurt alto en prote\u00ednas (YPRT) o prote\u00edna Whey (WPRT). Al inicio y al t\u00e9rmino de la intervenci\u00f3n se evaluar\u00e1 la composici\u00f3n corporal mediante DEXA, fuerza muscular, consumo m\u00e1ximo de ox\u00edgeno y perfil lip\u00eddico. Resultados Esperados: Se espera que el grupo YPRT logre incrementos similares o superiores en la fuerza muscular, masa libre de grasa, perfil lip\u00eddico y disminuci\u00f3n de la masa grasa y que el grupo WPRT.[\/vc_column_text][\/vc_column][\/vc_row][\/vc_section][vc_section css=\".vc_custom_1649209804184{background-color: #f6faff !important;}\" el_class=\"p-md-0 pt-md-5\"][vc_row el_class=\"container mx-auto align-items-center p-md-0 pt-5\"][vc_column el_class=\"p-0\"][\/vc_column][\/vc_row][\/vc_section][vc_section css=\".vc_custom_1649210787516{background-color: #f6faff !important;}\" el_class=\"p-md-0 pt-md-5 pb-md-5\"][vc_row el_class=\"container mx-auto align-items-center\"][vc_column][\/vc_column][\/vc_row][\/vc_section]\n                                        <\/div>\n                                    <\/div>\n                                <\/div>\n                            <\/div><div class=\"mt-3\"><i class=\"fas fa-solid fa-user-tag fa-fw me-2\"><\/i><small class=\"text-muted\">Responsable Alterno<\/small><\/div><span class=\"caption-field-publish\"><\/span><\/div><\/div><\/div><\/div><\/div><div class=\"  circle--pattern-bottom-large col-sm-12 col-md-12 img-article\"><div class=\"holder-publish col-md-12\" style=\"border-bottom: 1px solid #EFB956\"><div class=\"content-holder h-100 component-border overflow-hidden row m-0 p-4 aling-items-center\"><ul class=\"p-0 list-style-none\"><li class=\"p-0 ms-1\"><i class=\"fa fa-regular fa-calendar fa-fw ms-1\"><\/i>Diciembre 2022 - Diciembre 2024<\/li><\/ul><div class=\"caption col-12 p-0 col-md-12 row m-0 align-items-center\"><div class=\"px-md-1\"><small class=\"badge rounded-pill fw-semibold\" style=\"background-color:#EFB956 !important; color:#FFF\">Adjudicado<\/small><small class=\"ms-2 badge rounded-pill fw-semibold\" style=\"background-color:#F0F1F3 !important; color:#797979\"><i class=\"fa fa-solid fa-lg fa-money-check-dollar fa-fw me-1\"><\/i>Centro Interuniversitario de Envejecimiento Saludable<\/small>\n                            <div class=\"accordion accordion-flush\" id=\"37024\">\n                                <div class=\"accordion-item\">\n                                    <h3 class=\"my-0 small-space pt-2 title-ss text-decoration-none accordion-header\">\n                                        <a role=\"button\" class=\"bg-transparent p-0\" href=\"\">\n                                            <i class=\"fas fa-solid fa-link fa-fw me-2\"><\/i>\n                                            Caracterizaci\u00f3n de la capacidad funcional y condici\u00f3n f\u00edsica de personas mayores de siete comunas de la zona centro-sur de Chile\n                                        <\/a><\/h3>\n                                    <div id=\"collapse-37024\" class=\"accordion-collapse collapse\" data-bs-parent=\"#37024\">\n                                        <div class=\"accordion-body p-0 pt-4 pb-4\">\n                                            [vc_section el_class=\"container mx-auto align-items-center circle--pattern\" css=\".vc_custom_1648956589196{padding-top: 3rem !important;}\"][vc_row el_class=\"pb-5\"][vc_column][vc_wp_custommenu nav_menu=\"6\"][uoh_breadcrumb_component automatic_breadcrumb=\"true\"][uoh_title_component title_dropdown=\"big\" title_decorator=\"true\"]{{title}}[\/uoh_title_component][vc_column_text css=\"\"]Proyecto que involucra a 7 universidades p\u00fablicas chilenas donde evaluaremos la condici\u00f3n f\u00edsica y capacidad funcional de personas mayores en siete diferentes comunas de la zona centro-sur de Chile y su asociaci\u00f3n con antecedentes bio-demogr\u00e1ficos.[\/vc_column_text][\/vc_column][\/vc_row][\/vc_section][vc_section css=\".vc_custom_1649209804184{background-color: #f6faff !important;}\" el_class=\"p-md-0 pt-md-5\"][vc_row el_class=\"container mx-auto align-items-center p-md-0 pt-5\"][vc_column el_class=\"p-0\"][\/vc_column][\/vc_row][\/vc_section][vc_section css=\".vc_custom_1649210787516{background-color: #f6faff !important;}\" el_class=\"p-md-0 pt-md-5 pb-md-5\"][vc_row el_class=\"container mx-auto align-items-center\"][vc_column][\/vc_column][\/vc_row][\/vc_section]\n                                        <\/div>\n                                    <\/div>\n                                <\/div>\n                            <\/div><div class=\"mt-3\"><i class=\"fas fa-solid fa-user-tag fa-fw me-2\"><\/i><small class=\"text-muted\">Responsable Alterno<\/small><\/div><span class=\"caption-field-publish\"><\/span><\/div><\/div><\/div><\/div><\/div><div class=\"  circle--pattern-bottom-large col-sm-12 col-md-12 img-article\"><div class=\"holder-publish col-md-12\" style=\"border-bottom: 1px solid #EFB956\"><div class=\"content-holder h-100 component-border overflow-hidden row m-0 p-4 aling-items-center\"><ul class=\"p-0 list-style-none\"><li class=\"p-0 ms-1 me-2\"><i class=\"fa fa-solid fa-id-card-clip fa-fw\"><\/i> CIES005<\/li><li class=\"p-0 ms-1\"><i class=\"fa fa-regular fa-calendar fa-fw ms-1\"><\/i>Octubre 2022 - Julio 2024<\/li><\/ul><div class=\"caption col-12 p-0 col-md-12 row m-0 align-items-center\"><div class=\"px-md-1\"><small class=\"badge rounded-pill fw-semibold\" style=\"background-color:#EFB956 !important; color:#FFF\">Adjudicado<\/small><small class=\"ms-2 badge rounded-pill fw-semibold\" style=\"background-color:#F0F1F3 !important; color:#797979\"><i class=\"fa fa-solid fa-lg fa-money-check-dollar fa-fw me-1\"><\/i>Ministerio de Educaci\u00f3n<\/small>\n                            <div class=\"accordion accordion-flush\" id=\"37019\">\n                                <div class=\"accordion-item\">\n                                    <h3 class=\"my-0 small-space pt-2 title-ss text-decoration-none accordion-header\">\n                                        <a role=\"button\" class=\"bg-transparent p-0\" href=\"\">\n                                            <i class=\"fas fa-solid fa-link fa-fw me-2\"><\/i>\n                                            Caracterizaci\u00f3n de la capacidad funcional  y condici\u00f3n f\u00edsica de personas mayores de siete comunas de la zona centro-sur de Chile\n                                        <\/a><\/h3>\n                                    <div id=\"collapse-37019\" class=\"accordion-collapse collapse\" data-bs-parent=\"#37019\">\n                                        <div class=\"accordion-body p-0 pt-4 pb-4\">\n                                            [vc_section el_class=\"container mx-auto align-items-center circle--pattern\" css=\".vc_custom_1648956589196{padding-top: 3rem !important;}\"][vc_row el_class=\"pb-5\"][vc_column][vc_wp_custommenu nav_menu=\"6\"][uoh_breadcrumb_component automatic_breadcrumb=\"true\"][uoh_title_component title_dropdown=\"big\" title_decorator=\"true\"]{{title}}[\/uoh_title_component][vc_column_text css=\"\"]mayores (PM) de 65 a\u00f1os superan el n\u00famero de menores de 5 a\u00f1os y se espera que para el a\u00f1o 2030 \u00e9sta cifra aumente en un 34%. Frente a esto, Chile tiene importantes desaf\u00edos orientados al desarrollo de estrategias que promuevan el envejecimiento activo y saludable. Se acepta que una buena condici\u00f3n f\u00edsica se relaciona con una mejor capacidad funcional y reducci\u00f3n de la mortalidad en PM. Si bien existen estudios de cohortes de PM en Chile como ALEXANDROS, n= 2311 y la encuesta nacional de calidad de vida en la vejez  (n=2.132), estas no est\u00e1n espec\u00edficamente orientadas a la evaluaci\u00f3n de la condici\u00f3n f\u00edsica y su relaci\u00f3n con la capacidad funcional de las personas y, adem\u00e1s, son cohortes pertenecientes principalmente a la Regi\u00f3n Metropolitana. \r\nEl prop\u00f3sito de este proyecto es caracterizar la condici\u00f3n f\u00edsica y capacidad funcional de personas mayores de siete diferentes comunas de la zona centro-sur de Chile y su relaci\u00f3n con caracter\u00edsticas bio-demogr\u00e1ficas, de manera que permita orientar pol\u00edticas y acciones necesarias e integrales para la mejora de estos par\u00e1metros considerados determinantes del envejecimiento activo y saludable. Adicionalmente, se espera iniciar una cohorte multi-regional para estudios longitudinales, como tambi\u00e9n, el inicio de un biobanco para futuros an\u00e1lisis de biomarcadores relacionados a sarcopenia, condici\u00f3n f\u00edsica y capacidad funcional.\r\nSe propone un dise\u00f1o transversal, en donde se incluir\u00e1n PM de 60 a\u00f1os y m\u00e1s,  capaces de caminar sin ayuda de otra persona al menos una distancia de 10 metros, pertenecientes a centros de Atenci\u00f3n Primaria o centros comunitarios de 7 comunas: Valpara\u00edso, Santiago, Rancagua, Talca, Chill\u00e1n, Temuco y Puerto Montt. Se excluir\u00e1n personas que presenten deterioro cognitivo, patolog\u00edas card\u00edacas, respiratorias, m\u00fasculo esquel\u00e9ticas o neurol\u00f3gicas que le impidan o tengan contraindicaci\u00f3n para realizar las evaluaciones o pruebas de rendimiento f\u00edsico, incapacidad para comunicarse o dependencia en las actividades b\u00e1sicas de la vida diaria seg\u00fan \u00cdndice de Barthel. \r\nEl tama\u00f1o muestral se ha estimado a partir de la poblaci\u00f3n total compuesta por el total de sujetos de las 7 comunas (279.991), utilizando los siguientes par\u00e1metros: N=total poblacional, Z2=3,84 (nivel de confianza 95%), p=prevalencia de sarcopenia (19,1%), p=1-p y d2=3% precisi\u00f3n o error de muestreo. La muestra calculada se ajust\u00f3 a un 30% de p\u00e9rdidas por lo que tama\u00f1o de muestra fue de 936 en total. La muestra ser\u00e1 seleccionada mediante muestreo aleatorio simple. \r\nSe  caracterizar\u00e1n antecedentes biodemogr\u00e1ficos, de salud,  capacidad funcional y condici\u00f3n f\u00edsica de las PM, a trav\u00e9s de la aplicaci\u00f3n de cuestionarios,  pruebas de condici\u00f3n f\u00edsica y test funcionales, todos validados y estandarizados en cada lugar de evaluaci\u00f3n.[\/vc_column_text][\/vc_column][\/vc_row][\/vc_section][vc_section css=\".vc_custom_1649209804184{background-color: #f6faff !important;}\" el_class=\"p-md-0 pt-md-5\"][vc_row el_class=\"container mx-auto align-items-center p-md-0 pt-5\"][vc_column el_class=\"p-0\"][\/vc_column][\/vc_row][\/vc_section][vc_section css=\".vc_custom_1649210787516{background-color: #f6faff !important;}\" el_class=\"p-md-0 pt-md-5 pb-md-5\"][vc_row el_class=\"container mx-auto align-items-center\"][vc_column][\/vc_column][\/vc_row][\/vc_section]\n                                        <\/div>\n                                    <\/div>\n                                <\/div>\n                            <\/div><div class=\"mt-3\"><i class=\"fas fa-solid fa-user-tag fa-fw me-2\"><\/i><small class=\"text-muted\">Responsable Alterno<\/small><\/div><span class=\"caption-field-publish\"><\/span><\/div><\/div><\/div><\/div><\/div><div class=\"  circle--pattern-bottom-large col-sm-12 col-md-12 img-article\"><div class=\"holder-publish col-md-12\" style=\"border-bottom: 1px solid #48A2F9\"><div class=\"content-holder h-100 component-border overflow-hidden row m-0 p-4 aling-items-center\"><ul class=\"p-0 list-style-none\"><li class=\"p-0 ms-1 me-2\"><i class=\"fa fa-solid fa-id-card-clip fa-fw\"><\/i> URO2295<\/li><li class=\"p-0 ms-1\"><i class=\"fa fa-regular fa-calendar fa-fw ms-1\"><\/i>Agosto 2022 - Enero 2025<\/li><\/ul><div class=\"caption col-12 p-0 col-md-12 row m-0 align-items-center\"><div class=\"px-md-1\"><small class=\"badge rounded-pill fw-semibold\" style=\"background-color:#48A2F9 !important; color:#FFF\">En Ejecuci\u00f3n<\/small><small class=\"ms-2 badge rounded-pill fw-semibold\" style=\"background-color:#F0F1F3 !important; color:#797979\"><i class=\"fa fa-solid fa-lg fa-money-check-dollar fa-fw me-1\"><\/i>Ministerio de Educaci\u00f3n<\/small>\n                            <div class=\"accordion accordion-flush\" id=\"36999\">\n                                <div class=\"accordion-item\">\n                                    <h3 class=\"my-0 small-space pt-2 title-ss text-decoration-none accordion-header\">\n                                        <a role=\"button\" class=\"bg-transparent p-0\" href=\"\">\n                                            <i class=\"fas fa-solid fa-link fa-fw me-2\"><\/i>\n                                            Fortalecimiento de estrategias comunitarias de promoci\u00f3n de la salud, prevenci\u00f3n y tratamiento temprano y oportuno de enfermedades cr\u00f3nicas no transmisibles con foco en actividad f\u00edsica y nutrici\u00f3n saludable\n                                        <\/a><\/h3>\n                                    <div id=\"collapse-36999\" class=\"accordion-collapse collapse\" data-bs-parent=\"#36999\">\n                                        <div class=\"accordion-body p-0 pt-4 pb-4\">\n                                            [vc_section el_class=\"container mx-auto align-items-center circle--pattern\" css=\".vc_custom_1648956589196{padding-top: 3rem !important;}\"][vc_row el_class=\"pb-5\"][vc_column][vc_wp_custommenu nav_menu=\"6\"][uoh_breadcrumb_component automatic_breadcrumb=\"true\"][uoh_title_component title_dropdown=\"big\" title_decorator=\"true\"]{{title}}[\/uoh_title_component][vc_column_text css=\"\"]URO 2295. El Ministerio de Educaci\u00f3n a trav\u00e9s del Departamento de Fortalecimiento Institucional de la Subsecretaria de Educaci\u00f3n Superior financia proyectos que permitan contribuir al desarrollo social y territorial, a nivel local y\/o regional, a trav\u00e9s de la generaci\u00f3n compartida de conocimientos, oportunidades de desarrollo y\/o beneficios entre las instituciones de educaci\u00f3n superior y los actores sociales, tanto p\u00fablicos como privados. En este contexto, este proyecto busca generar estrategias eficaces \u0096 con la comunidad y distintos actores sociales de la regi\u00f3n \u0096 y basadas en la evidencia que aborden el aumento de la prevalencia de enfermedades cr\u00f3nicas no transmisibles a trav\u00e9s de la mejora de los patrones de actividad f\u00edsica y alimentarios de la poblaci\u00f3n regional. \r\nObjetivo general: Fortalecer las estrategias comunitarias de promoci\u00f3n de la salud, prevenci\u00f3n y tratamiento temprano y oportuno de enfermedades cr\u00f3nicas no transmisibles en la Regi\u00f3n de O\u0092Higgins con foco en actividad f\u00edsica y nutrici\u00f3n saludable[\/vc_column_text][\/vc_column][\/vc_row][\/vc_section][vc_section css=\".vc_custom_1649209804184{background-color: #f6faff !important;}\" el_class=\"p-md-0 pt-md-5\"][vc_row el_class=\"container mx-auto align-items-center p-md-0 pt-5\"][vc_column el_class=\"p-0\"][\/vc_column][\/vc_row][\/vc_section][vc_section css=\".vc_custom_1649210787516{background-color: #f6faff !important;}\" el_class=\"p-md-0 pt-md-5 pb-md-5\"][vc_row el_class=\"container mx-auto align-items-center\"][vc_column][\/vc_column][\/vc_row][\/vc_section]\n                                        <\/div>\n                                    <\/div>\n                                <\/div>\n                            <\/div><div class=\"mt-3\"><i class=\"fas fa-solid fa-user-tag fa-fw me-2\"><\/i><small class=\"text-muted\">Co-Investigador\/a<\/small><\/div><span class=\"caption-field-publish\"><\/span><\/div><\/div><\/div><\/div><\/div><div class=\"  circle--pattern-bottom-large col-sm-12 col-md-12 img-article\"><div class=\"holder-publish col-md-12\" style=\"border-bottom: 1px solid #48A2F9\"><div class=\"content-holder h-100 component-border overflow-hidden row m-0 p-4 aling-items-center\"><ul class=\"p-0 list-style-none\"><li class=\"p-0 ms-1\"><i class=\"fa fa-regular fa-calendar fa-fw ms-1\"><\/i>Marzo 2022 - Febrero 2024<\/li><\/ul><div class=\"caption col-12 p-0 col-md-12 row m-0 align-items-center\"><div class=\"px-md-1\"><small class=\"badge rounded-pill fw-semibold\" style=\"background-color:#48A2F9 !important; color:#FFF\">En Ejecuci\u00f3n<\/small><small class=\"ms-2 badge rounded-pill fw-semibold\" style=\"background-color:#F0F1F3 !important; color:#797979\"><i class=\"fa fa-solid fa-lg fa-money-check-dollar fa-fw me-1\"><\/i>Agencia Nacional de Investigaci\u00f3n y Desarrollo - ANID<\/small>\n                            <div class=\"accordion accordion-flush\" id=\"36963\">\n                                <div class=\"accordion-item\">\n                                    <h3 class=\"my-0 small-space pt-2 title-ss text-decoration-none accordion-header\">\n                                        <a role=\"button\" class=\"bg-transparent p-0\" href=\"\">\n                                            <i class=\"fas fa-solid fa-link fa-fw me-2\"><\/i>\n                                            The epidemiology of antimicrobial resistance in a region with intense aquaculture activity: evaluating the role of bivalve mollusks as sentinel organisms and potential impacts on public health\n                                        <\/a><\/h3>\n                                    <div id=\"collapse-36963\" class=\"accordion-collapse collapse\" data-bs-parent=\"#36963\">\n                                        <div class=\"accordion-body p-0 pt-4 pb-4\">\n                                            [vc_section el_class=\"container mx-auto align-items-center circle--pattern\" css=\".vc_custom_1648956589196{padding-top: 3rem !important;}\"][vc_row el_class=\"pb-5\"][vc_column][vc_wp_custommenu nav_menu=\"6\"][uoh_breadcrumb_component automatic_breadcrumb=\"true\"][uoh_title_component title_dropdown=\"big\" title_decorator=\"true\"]{{title}}[\/uoh_title_component][vc_column_text css=\"\"]Antimicrobial resistance (AMR) is a phenomenon that happens when bacteria become tolerant to antibiotics used to treat the infections they cause. Antibiotics are key therapeutic tools to treat many human and animal infectious diseases; consequently, keeping their activity on bacteria is fundamental for public and animal health. Aquaculture farming is known for using large amounts of antibiotics, making this activity particularly relevant in development and spread of AMR in aquatic environments. There is evidence in Chile that aquaculture activity increases the presence of resistant bacteria and their corresponding genes in marine sediments directly impacted by salmon farms; however, these evaluations are limited to few locations which hampers a generalization of these conclusions to other salmon farming sites in Chilean waters. There is also evidence suggesting that aquaculture-associated resistance genes present in marine sediments might be transferred to bacteria with pathogenic potential in humans such as Escherichia coli, but no studies have reported the presence of resistance traits in such bacteria in the marine environment from areas impacted by salmon farming in Chile. In countries like Norway, bivalve mollusks are used to monitor antibiotic resistance in Enterobacteria in the marine environment; therefore, they could also be useful for monitoring AMR associated with salmon farming and other anthropogenic sources in Chile. Sampling of bivalve mollusks represents an important logistical advantage to complex and expensive seabed sediment sampling. Los Lagos is the region with the highest historical production of farmed salmon in Chile; then, it is a suitable area to investigate the impact of aquaculture-sourced AMR in the marine environment.\r\nThe general objective of this proposal is to investigate aquaculture-associated AMR in the marine environment of Los Lagos region from an epidemiologic approach, using bivalve mollusks as sentinel organisms and E. coli as the indicator bacterium. Specific objectives include: 1) to detect, characterize and estimate the prevalence of AMR in E. coli isolated from bivalve mollusks in the Los Lagos region, through a region-level sampling; 2) to study the spatial variability of AMR in E. coli isolated from bivalve mollusks from Los Lagos region; 3) to evaluate the effect of salmon farming activity on the richness and intensity of AMR in E. coli isolated from bivalves from Los Lagos region, controlling for potential confounding factors; and 4) to determine whether significant differences exist in the accumulation of E. coli and resistant E. coli in bivalve mollusks between the sampled bivalve species, accounting for environmental and biological factors.\r\nBivalve mollusks samples will be obtained the 130 sampling stations set along the coast of Los Lagos by the National Program for Surveillance and Control of Harmful Algal Blooms Intoxications (red tides) coordinated by the Ministry of Health. Thirty-three additional sampling stations will be set in the same study area in order to achieve the calculated total sample size of 163 sampling stations. At each sampling station bivalve mollusks will be sampled to quantify E. coli and to detect and characterize both phenotypic and genotypic AMR in this bacterium. The study will be focused in 29 antimicrobial resistance genes (ARGs) and 20 antibiotics commonly used in salmon farming or for which resistance has been detected in previous studies. The antimicrobial susceptibility will be performed by estimating the minimal inhibitory concentrations (MICs) for each antibiotic using the VITEK2 technology. The genotypic analysis will be carried out by means of the detection target ARGs, through PCR. Spatial clustering will be examined for each antibiotic tested using MIC values and the ARG richness index; global clustering will be evaluated through the Moran\u0092s I statistic, while local clustering will be examined by means of the spatial scan statistic. ARG richness will be modeled as a function of the local salmon farming intensity expressed as the number of active salmon farms within 10 km seaway distance from the bivalve sampling location, using a Poisson mixed-effects model in order to control for other AMR sources and important environmental variables. Similar models will be constructed using MICs as the outcome for antimicrobials that show substantial variability in this parameter. Finally, the abundance of both total and resistant E. coli (MPN\/100g) found in bivalve mollusks will be modeled as a function of the bivalve species sampled, accounting for bivalve size, water temperature, local salmon farming intensity and distance to other AMR sources, using a mixed-effect linear regression model.\r\nThis study will contribute to characterize and to identify the main drivers of the environmental AMR in an area with intense salmon farming activity, and it will help to understand how this AMR can impact public health through potential pathogenic bacteria. In practice, this proposal will be the first extensive epidemiological study in this matter in Chile. Moreover, this proposal will help to determine which bivalve mollusks species are suitable to monitor AMR in environments impacted by salmon farming. All this information will be crucial to set the foundations for a future AMR monitoring program in areas of intense aquaculture.[\/vc_column_text][\/vc_column][\/vc_row][\/vc_section][vc_section css=\".vc_custom_1649209804184{background-color: #f6faff !important;}\" el_class=\"p-md-0 pt-md-5\"][vc_row el_class=\"container mx-auto align-items-center p-md-0 pt-5\"][vc_column el_class=\"p-0\"][\/vc_column][\/vc_row][\/vc_section][vc_section css=\".vc_custom_1649210787516{background-color: #f6faff !important;}\" el_class=\"p-md-0 pt-md-5 pb-md-5\"][vc_row el_class=\"container mx-auto align-items-center\"][vc_column][\/vc_column][\/vc_row][\/vc_section]\n                                        <\/div>\n                                    <\/div>\n                                <\/div>\n                            <\/div><div class=\"mt-3\"><i class=\"fas fa-solid fa-user-tag fa-fw me-2\"><\/i><small class=\"text-muted\">Investigador\/a Responsable<\/small><\/div><span class=\"caption-field-publish\"><\/span><\/div><\/div><\/div><\/div><\/div><div class=\"  circle--pattern-bottom-large col-sm-12 col-md-12 img-article\"><div class=\"holder-publish col-md-12\" style=\"border-bottom: 1px solid #35DB54\"><div class=\"content-holder h-100 component-border overflow-hidden row m-0 p-4 aling-items-center\"><ul class=\"p-0 list-style-none\"><li class=\"p-0 ms-1\"><i class=\"fa fa-regular fa-calendar fa-fw ms-1\"><\/i>Enero 2022 - Diciembre 2024<\/li><\/ul><div class=\"caption col-12 p-0 col-md-12 row m-0 align-items-center\"><div class=\"px-md-1\"><small class=\"badge rounded-pill fw-semibold\" style=\"background-color:#35DB54 !important; color:#FFF\">Finalizado<\/small><small class=\"ms-2 badge rounded-pill fw-semibold\" style=\"background-color:#F0F1F3 !important; color:#797979\"><i class=\"fa fa-solid fa-lg fa-money-check-dollar fa-fw me-1\"><\/i>Ministerio de Educaci\u00f3n<\/small>\n                            <div class=\"accordion accordion-flush\" id=\"36991\">\n                                <div class=\"accordion-item\">\n                                    <h3 class=\"my-0 small-space pt-2 title-ss text-decoration-none accordion-header\">\n                                        <a role=\"button\" class=\"bg-transparent p-0\" href=\"\">\n                                            <i class=\"fas fa-solid fa-link fa-fw me-2\"><\/i>\n                                            Sistema Articulado de Investigaci\u00f3n en Cambio Clim\u00e1tico y Sustentabilidad de Zonas Costeras de Chile (URO RED21992)\n                                        <\/a><\/h3>\n                                    <div id=\"collapse-36991\" class=\"accordion-collapse collapse\" data-bs-parent=\"#36991\">\n                                        <div class=\"accordion-body p-0 pt-4 pb-4\">\n                                            [vc_section el_class=\"container mx-auto align-items-center circle--pattern\" css=\".vc_custom_1648956589196{padding-top: 3rem !important;}\"][vc_row el_class=\"pb-5\"][vc_column][vc_wp_custommenu nav_menu=\"6\"][uoh_breadcrumb_component automatic_breadcrumb=\"true\"][uoh_title_component title_dropdown=\"big\" title_decorator=\"true\"]{{title}}[\/uoh_title_component][vc_column_text css=\"\"]Sistema Articulado de Investigaci\u00f3n en Cambio Clim\u00e1tico y Sustentabilidad de Zonas Costeras de Chile CUECH\/RISUE RED21992[\/vc_column_text][\/vc_column][\/vc_row][\/vc_section][vc_section css=\".vc_custom_1649209804184{background-color: #f6faff !important;}\" el_class=\"p-md-0 pt-md-5\"][vc_row el_class=\"container mx-auto align-items-center p-md-0 pt-5\"][vc_column el_class=\"p-0\"][\/vc_column][\/vc_row][\/vc_section][vc_section css=\".vc_custom_1649210787516{background-color: #f6faff !important;}\" el_class=\"p-md-0 pt-md-5 pb-md-5\"][vc_row el_class=\"container mx-auto align-items-center\"][vc_column][\/vc_column][\/vc_row][\/vc_section]\n                                        <\/div>\n                                    <\/div>\n                                <\/div>\n                            <\/div><div class=\"mt-3\"><i class=\"fas fa-solid fa-user-tag fa-fw me-2\"><\/i><small class=\"text-muted\">Co-Investigador\/a<\/small><\/div><span class=\"caption-field-publish\"><\/span><\/div><\/div><\/div><\/div><\/div><div class=\"  circle--pattern-bottom-large col-sm-12 col-md-12 img-article\"><div class=\"holder-publish col-md-12\" style=\"border-bottom: 1px solid #EFB956\"><div class=\"content-holder h-100 component-border overflow-hidden row m-0 p-4 aling-items-center\"><ul class=\"p-0 list-style-none\"><li class=\"p-0 ms-1\"><i class=\"fa fa-regular fa-calendar fa-fw ms-1\"><\/i>Diciembre 2021 - Noviembre 2023<\/li><\/ul><div class=\"caption col-12 p-0 col-md-12 row m-0 align-items-center\"><div class=\"px-md-1\"><small class=\"badge rounded-pill fw-semibold\" style=\"background-color:#EFB956 !important; color:#FFF\">Adjudicado<\/small>\n                            <div class=\"accordion accordion-flush\" id=\"37003\">\n                                <div class=\"accordion-item\">\n                                    <h3 class=\"my-0 small-space pt-2 title-ss text-decoration-none accordion-header\">\n                                        <a role=\"button\" class=\"bg-transparent p-0\" href=\"\">\n                                            <i class=\"fas fa-solid fa-link fa-fw me-2\"><\/i>\n                                            Creacion de imagenes de super-resolucion ultrasonicas en placentas humanas ex vivo\n                                        <\/a><\/h3>\n                                    <div id=\"collapse-37003\" class=\"accordion-collapse collapse\" data-bs-parent=\"#37003\">\n                                        <div class=\"accordion-body p-0 pt-4 pb-4\">\n                                            [vc_section el_class=\"container mx-auto align-items-center circle--pattern\" css=\".vc_custom_1648956589196{padding-top: 3rem !important;}\"][vc_row el_class=\"pb-5\"][vc_column][vc_wp_custommenu nav_menu=\"6\"][uoh_breadcrumb_component automatic_breadcrumb=\"true\"][uoh_title_component title_dropdown=\"big\" title_decorator=\"true\"]{{title}}[\/uoh_title_component][vc_column_text css=\"\"]El desarrollo de herramientas para el an &#769;alisis de funciones vitales a trav &#769;es de im &#769;agenes representa un campo de creciente inter &#769;es, especialmente para el estudio de marcadores tempranos de diversas patolog &#769;&#305;as, as &#769;&#305; como el desarrollo de aplicaciones diagn &#769;osticas a mediano plazo. En este contexto, el an &#769;alisis de la funci &#769;on vascular, a lo largo del ciclo vital, continua siendo un  &#769;area con un alta demanda de nuevas tecnolog &#769;&#305;as, debido a su gran impacto a nivel de salud en la poblaci &#769;on. Esta propuesta busca generar una l &#769;&#305;nea de investigaci &#769;on actualmente casi inexistente en Chile, las im &#769;agenes ultras &#769;onicas m &#769;edicas. En particular, nos gustar &#769;&#305;a introducir en Chile una t &#769;ecnica recientemente propuesta, denominada microscop &#769;&#305;a de localizaci &#769;on por ultrasonido (ULM), tambi &#769;en conocida como im &#769;agenes de su &#769;per- resoluci &#769;on. Esta t &#769;ecnica puede crear im &#769;agenes del sistema circulatoria con una resoluci &#769;on nunca antes vista, lo que permite visualizar vasos sangu &#769;&#305;neos de hasta 5&#956;m. As &#769;&#305;, nuestra propuesta posee dos grandes objetivos. El primero es Optimizar y robusteces los procesos involucrados en el desarrollo de las im &#769;agenes de su &#769;per-resoluci &#769;on ultras &#769;onicas, esto a trav &#769;es de Optimizar los par &#769;ametros de adquisici &#769;on de datos y de procesamiento con el fin de robustecer la generaci &#769;on de este tipo de im &#769;agenes. Nuestro segundo objetivo es generar im &#769;agenes de su &#769;per- resoluci &#769;on de la red vascular interna de placenta humana ex-vivo y a buscar candidatos a marcadores a partir de estas im &#769;agenes.\r\nLa ecograf &#769;&#305;a convencional es ampliamente usada en Chile y el mundo. Es preferida entre otras modalidades de im &#769;agenes (MRI, PET, TC) debido a su portabilidad, bajo costo, naturaleza no invasiva y a que utiliza radiaci &#769;on no ionizante, especialmente en condiciones como el embarazo, o en pacientes con manejo farmacol &#769;ogico complejo, entre otras. Recientemente, se han desarrollado nuevas modalidades de im &#769;agenes ultras &#769;onicas, propiciadas por la mejora en la industria de los semiconductores, lo que ha permitido un incremento en la capacidad de computo de los esc &#769;aneres ultraso &#769;nicos y en el nu &#769;mero de elementos piezoel &#769;ectrico de los transductores ultras &#769;onicos, generando un aumento significativo en la versatilidad y calidad de estas tecnolog &#769;&#305;as. Dentro de estas nuevas t &#769;ecnicas encontramos la microscop &#769;&#305;a de localizaci &#769;on por ultrasonido (ULM) o su &#769;per-resoluci &#769;on ultras &#769;onica. Esta revolucionaria t &#769;ecnica es capaz de superar el l &#769;&#305;mite de difracci &#769;on y producir una resoluci &#769;on diez veces mayor en comparaci &#769;on con la ecograf &#769;&#305;a convencional. Puede ser usada para producir ima &#769;genes vasculares con una resoluci &#769;on sin precedentes de hasta 5 &#956;m permitiendo as &#769;&#305; la visualizaci &#769;on de vasos sangu &#769;&#305;neos microsc &#769;opicos que hasta ahora no pueden ser vistos por ninguna t &#769;ecnica disponible cl &#769;&#305;nicamente. ULM utiliza microburbujas (MBs) de gas (1 &#956;m de di &#769;ametro) que actu &#769;an como fuentes acu &#769;sticas estoc &#769;asticas. Las MBs se inyectan en el torrente sangu &#769;&#305;neo y fluyen dentro del sistema circulatorio, donde aparecen y desaparecen de la regi &#769;on de inter &#769;es, lo que permite su localizaci &#769;on. Luego, la imagen de su &#769;per-resoluci &#769;on se construye a partir de la acumulaci &#769;on de cientos de miles de MBs localizadas.\r\nActualmente, la mayor parte de la investigaci &#769;on en ULM se realiza desde el punto de vista de las ciencias de la ingenier &#769;&#305;a, que deja a veces a la ciencia fundamental como un aspecto secundario. Nuestro equipo, debido al car &#769;acter transdisciplinario de esta propuesta, esta constituido por investigadores de el  &#769;area de la ingenier &#769;&#305;a, f &#769;&#305;sica, biomedicina y matem &#769;aticas. Basados en las fortalezas de este equipo, proponemos estudiar esta tecnolog &#769;&#305;a desde la perspectiva de la ciencia fundamental, buscando limitaciones en ella, y estableciendo los mecanismos fisiol &#769;ogicos que se manifiestan a nivel de las im &#769;agenes de su &#769;per-resoluci &#769;on, permitiendo superar sus actuales limitaciones y potenciando su posible aplicaci &#769;on en el  &#769;area m &#769;edica. En este contexto buscaremos como segundo objetivo el visualizar la microvasculatura de muestras de placenta ex-vivo, las que ser &#769;an donadas voluntariamente por pacientes del hospital regional de Rancagua, y complementar estas observaciones con par &#769;ametros funcionales y moleculares, con el fin de modelar desde distintas perspectivas nuevos marcadores de funci &#769;on vascular.\r\nUsualmente para lograr el avance en le desarrollo de este tipo de t &#769;ecnicas, se requieren condiciones experimentales altamente controlables, las que se logran utilizando sistemas que imitan el tejido en cuesti &#769;on, el que en nuestro caso es el sistema vascular. Para esto, se utilizan mayormente experimentos in-vitro fabricados a partir de microtubos de 50&#8722;150 &#956;m de di &#769;ametro interno. Sin embargo, existe una gran diferencia entre las propiedades de este tipo de sistemas y las propiedades acu &#769;sticas de tejido in-vivo humano. Lo que requiere una gran cantidad de iteraciones experimentales retazando el desarrollo. As &#769;&#305;, al utilizar tejido humano ex-vivo pretendemos aumentar significativamente la velocidad de la curva de aprendizaje y por consiguiente lograr im &#769;agenes de su &#769;per-resoluci &#769;on humano compatibles dentro de la duraci &#769;on de esta propuesta. As &#769;&#305; mismo, el desarrollo de esta propuesta en un modelo vascular como la placenta humana representa un clara oportunidad para aportar en un  &#769;area actualmente limitada en su capacidad diagn &#769;ostica, lo que restringe la aplicaci &#769;on de intervenciones efectivas durante el embarazo, con consecuencias en la salud de la madre y su progenie.\r\nComo proyecciones de este esquema colaborativo esperamos tener acceso a par &#769;ametros biol &#769;ogicos con los cuales generar nuevas formas de diagn &#769;ostico de alta precisi &#769;on, en especial a nivel de las estructuras involucradas, en primera instancia, con el desarrollo de alteraciones vasculares (i.e. vasos de pequen &#771;o calibre). Con ello buscamos desarrollar un tecnolog &#769;&#305;a con base cient &#769;&#305;fica a trav &#769;es de la cual ser &#769;a posible obtener indicadores de mayor sensibilidad y especificidad para variadas condiciones, enfermedades o s &#769;&#305;ndromes, relacionados con la funci &#769;on vascular.[\/vc_column_text][\/vc_column][\/vc_row][\/vc_section][vc_section css=\".vc_custom_1649209804184{background-color: #f6faff !important;}\" el_class=\"p-md-0 pt-md-5\"][vc_row el_class=\"container mx-auto align-items-center p-md-0 pt-5\"][vc_column el_class=\"p-0\"][\/vc_column][\/vc_row][\/vc_section][vc_section css=\".vc_custom_1649210787516{background-color: #f6faff !important;}\" el_class=\"p-md-0 pt-md-5 pb-md-5\"][vc_row el_class=\"container mx-auto align-items-center\"][vc_column][\/vc_column][\/vc_row][\/vc_section]\n                                        <\/div>\n                                    <\/div>\n                                <\/div>\n                            <\/div><div class=\"mt-3\"><i class=\"fas fa-solid fa-user-tag fa-fw me-2\"><\/i><small class=\"text-muted\">Co-Investigador\/a<\/small><\/div><span class=\"caption-field-publish\"><\/span><\/div><\/div><\/div><\/div><\/div><div class=\"  circle--pattern-bottom-large col-sm-12 col-md-12 img-article\"><div class=\"holder-publish col-md-12\" style=\"border-bottom: 1px solid #EFB956\"><div class=\"content-holder h-100 component-border overflow-hidden row m-0 p-4 aling-items-center\"><ul class=\"p-0 list-style-none\"><li class=\"p-0 ms-1\"><i class=\"fa fa-regular fa-calendar fa-fw ms-1\"><\/i>Diciembre 2021 - Diciembre 2022<\/li><\/ul><div class=\"caption col-12 p-0 col-md-12 row m-0 align-items-center\"><div class=\"px-md-1\"><small class=\"badge rounded-pill fw-semibold\" style=\"background-color:#EFB956 !important; color:#FFF\">Adjudicado<\/small><small class=\"ms-2 badge rounded-pill fw-semibold\" style=\"background-color:#F0F1F3 !important; color:#797979\"><i class=\"fa fa-solid fa-lg fa-money-check-dollar fa-fw me-1\"><\/i>Ministerio de Ciencia, Tecnolog\u00eda, Conocimiento e Innovaci\u00f3n<\/small>\n                            <div class=\"accordion accordion-flush\" id=\"37007\">\n                                <div class=\"accordion-item\">\n                                    <h3 class=\"my-0 small-space pt-2 title-ss text-decoration-none accordion-header\">\n                                        <a role=\"button\" class=\"bg-transparent p-0\" href=\"\">\n                                            <i class=\"fas fa-solid fa-link fa-fw me-2\"><\/i>\n                                            Divas de la Ciencia\u0094 Mujeres del Pasado Inspirando al Futuro\n                                        <\/a><\/h3>\n                                    <div id=\"collapse-37007\" class=\"accordion-collapse collapse\" data-bs-parent=\"#37007\">\n                                        <div class=\"accordion-body p-0 pt-4 pb-4\">\n                                            [vc_section el_class=\"container mx-auto align-items-center circle--pattern\" css=\".vc_custom_1648956589196{padding-top: 3rem !important;}\"][vc_row el_class=\"pb-5\"][vc_column][vc_wp_custommenu nav_menu=\"6\"][uoh_breadcrumb_component automatic_breadcrumb=\"true\"][uoh_title_component title_dropdown=\"big\" title_decorator=\"true\"]{{title}}[\/uoh_title_component][vc_column_text css=\"\"]Cuando pensamos en cient\u00edficos y su aporte a la ciencia, generalmente reconocemos un estereotipo masculino, acompa\u00f1ado de un desconocimiento del rol de la mujer en la ciencia. En nuestro pa\u00eds el n\u00famero de cient\u00edficos va en aumento, en n\u00famero de cient\u00edficas es de aproximadamente un 30% en las diferentes regiones del pa\u00eds. Conjuntamente,  la ciencia es reconocida como un proceso centralizado y debido a la baja difusi\u00f3n y divulgaci\u00f3n, el reconocimiento de referentes nacionales es reducido. La promoci\u00f3n del conocimiento a trav\u00e9s de sus actores en estudiantes de colegio puede incentivar la vocaci\u00f3n cient\u00edfica y promover la equidad de g\u00e9nero en \u00e1reas masculinizadas. El objetivo general de esta propuesta es: Promover el reconocimiento de Grandes Cient\u00edficas hist\u00f3ricas y de Cient\u00edfico(a)s Regionales a trav\u00e9s de la serie \u0093Divas de la Ciencia\u0094 dirigido tanto a estudiantes de colegios como al p\u00fablico general. Los objetivos espec\u00edficos son: 1) Visibilizar a Grandes Cient\u00edficas con el fin de promover su reconocimiento por el p\u00fablico general, 2) Promocionar a Cient\u00edfico(a)s Regionales como nuevos referentes cient\u00edficos por el p\u00fablico general, y 3) Integrar la serie como herramienta de ense\u00f1anza\/aprendizaje a las clases de ciencia en colegios del pa\u00eds. La serie constar\u00e1 de 12 episodios, y cada entrega tendr\u00e1 una presentaci\u00f3n animada de una \u0093Diva\u0094 (3 min) enlazada a la investigaci\u00f3n del Cient\u00edfico(a) Regional (5 min), y divulgada en un canal de YouTube. El dise\u00f1o de los episodios espera generar una experiencia memorable al exponer los problemas que debi\u00f3 enfrentar cada \u0093Diva\u0094 para lograr su investigaci\u00f3n en conjunto con la identificaci\u00f3n con el\/la Cient\u00edfico\/a Regional; adem\u00e1s de utilizar un lenguaje cercano y sencillo, musicalizaci\u00f3n y movimientos de las animaciones digitales. Los cap\u00edtulos estar\u00e1n divididos en tres ciclos de acuerdo a los programas del Mineduc: 7\u00ba-8\u00ba b\u00e1sico (ciclo I), 1\u00ba-2\u00ba Medio (ciclo II), y 3\u00ba-4\u00ba medio (ciclo III). Adem\u00e1s, los profesores interesados ser\u00e1n capacitados para utilizar la serie en sus clases a trav\u00e9s de una gu\u00eda de actividades pr\u00e1cticas. Toda la propuesta no tendr\u00e1 costo alguno para los participantes.[\/vc_column_text][\/vc_column][\/vc_row][\/vc_section][vc_section css=\".vc_custom_1649209804184{background-color: #f6faff !important;}\" el_class=\"p-md-0 pt-md-5\"][vc_row el_class=\"container mx-auto align-items-center p-md-0 pt-5\"][vc_column el_class=\"p-0\"][\/vc_column][\/vc_row][\/vc_section][vc_section css=\".vc_custom_1649210787516{background-color: #f6faff !important;}\" el_class=\"p-md-0 pt-md-5 pb-md-5\"][vc_row el_class=\"container mx-auto align-items-center\"][vc_column][\/vc_column][\/vc_row][\/vc_section]\n                                        <\/div>\n                                    <\/div>\n                                <\/div>\n                            <\/div><div class=\"mt-3\"><i class=\"fas fa-solid fa-user-tag fa-fw me-2\"><\/i><small class=\"text-muted\">Investigador\/a Responsable<\/small><\/div><span class=\"caption-field-publish\"><\/span><\/div><\/div><\/div><\/div><\/div><div class=\"  circle--pattern-bottom-large col-sm-12 col-md-12 img-article\"><div class=\"holder-publish col-md-12\" style=\"border-bottom: 1px solid #48A2F9\"><div class=\"content-holder h-100 component-border overflow-hidden row m-0 p-4 aling-items-center\"><ul class=\"p-0 list-style-none\"><li class=\"p-0 ms-1 me-2\"><i class=\"fa fa-solid fa-id-card-clip fa-fw\"><\/i> 1211962<\/li><li class=\"p-0 ms-1\"><i class=\"fa fa-regular fa-calendar fa-fw ms-1\"><\/i>Noviembre 2021 - Octubre 2025<\/li><\/ul><div class=\"caption col-12 p-0 col-md-12 row m-0 align-items-center\"><div class=\"px-md-1\"><small class=\"badge rounded-pill fw-semibold\" style=\"background-color:#48A2F9 !important; color:#FFF\">En Ejecuci\u00f3n<\/small><small class=\"ms-2 badge rounded-pill fw-semibold\" style=\"background-color:#F0F1F3 !important; color:#797979\"><i class=\"fa fa-solid fa-lg fa-money-check-dollar fa-fw me-1\"><\/i>Agencia Nacional de Investigaci\u00f3n y Desarrollo - ANID<\/small>\n                            <div class=\"accordion accordion-flush\" id=\"37016\">\n                                <div class=\"accordion-item\">\n                                    <h3 class=\"my-0 small-space pt-2 title-ss text-decoration-none accordion-header\">\n                                        <a role=\"button\" class=\"bg-transparent p-0\" href=\"\">\n                                            <i class=\"fas fa-solid fa-link fa-fw me-2\"><\/i>\n                                            Effects of eccentric, concentric and eccentric\/concentric training on muscle function and mass, functional performance, cardiometabolic health, quality of life and molecular adaptations of skeletal muscle in COPD patients: a multicenter randomized trial\n                                        <\/a><\/h3>\n                                    <div id=\"collapse-37016\" class=\"accordion-collapse collapse\" data-bs-parent=\"#37016\">\n                                        <div class=\"accordion-body p-0 pt-4 pb-4\">\n                                            [vc_section el_class=\"container mx-auto align-items-center circle--pattern\" css=\".vc_custom_1648956589196{padding-top: 3rem !important;}\"][vc_row el_class=\"pb-5\"][vc_column][vc_wp_custommenu nav_menu=\"6\"][uoh_breadcrumb_component automatic_breadcrumb=\"true\"][uoh_title_component title_dropdown=\"big\" title_decorator=\"true\"]{{title}}[\/uoh_title_component][vc_column_text css=\"\"]Es proyecto busca comparar los  efectos de diversos programas de ejercicio f\u00edsico en diversos parametros pronosticos en pacientes con EPOC severo[\/vc_column_text][\/vc_column][\/vc_row][\/vc_section][vc_section css=\".vc_custom_1649209804184{background-color: #f6faff !important;}\" el_class=\"p-md-0 pt-md-5\"][vc_row el_class=\"container mx-auto align-items-center p-md-0 pt-5\"][vc_column el_class=\"p-0\"][\/vc_column][\/vc_row][\/vc_section][vc_section css=\".vc_custom_1649210787516{background-color: #f6faff !important;}\" el_class=\"p-md-0 pt-md-5 pb-md-5\"][vc_row el_class=\"container mx-auto align-items-center\"][vc_column][\/vc_column][\/vc_row][\/vc_section]\n                                        <\/div>\n                                    <\/div>\n                                <\/div>\n                            <\/div><div class=\"mt-3\"><i class=\"fas fa-solid fa-user-tag fa-fw me-2\"><\/i><small class=\"text-muted\">Co-Investigador\/a<\/small><\/div><span class=\"caption-field-publish\"><\/span><\/div><\/div><\/div><\/div><\/div><div class=\"  circle--pattern-bottom-large col-sm-12 col-md-12 img-article\"><div class=\"holder-publish col-md-12\" style=\"border-bottom: 1px solid #EFB956\"><div class=\"content-holder h-100 component-border overflow-hidden row m-0 p-4 aling-items-center\"><ul class=\"p-0 list-style-none\"><li class=\"p-0 ms-1\"><i class=\"fa fa-regular fa-calendar fa-fw ms-1\"><\/i>Julio 2021 - Julio 2023<\/li><\/ul><div class=\"caption col-12 p-0 col-md-12 row m-0 align-items-center\"><div class=\"px-md-1\"><small class=\"badge rounded-pill fw-semibold\" style=\"background-color:#EFB956 !important; color:#FFF\">Adjudicado<\/small>\n                            <div class=\"accordion accordion-flush\" id=\"37001\">\n                                <div class=\"accordion-item\">\n                                    <h3 class=\"my-0 small-space pt-2 title-ss text-decoration-none accordion-header\">\n                                        <a role=\"button\" class=\"bg-transparent p-0\" href=\"\">\n                                            <i class=\"fas fa-solid fa-link fa-fw me-2\"><\/i>\n                                            Creaci\u00f3n de im\u00e1genes de super-resoluci\u00f3n ultras\u00f3nicas en placentas humanas ex-vivo\n                                        <\/a><\/h3>\n                                    <div id=\"collapse-37001\" class=\"accordion-collapse collapse\" data-bs-parent=\"#37001\">\n                                        <div class=\"accordion-body p-0 pt-4 pb-4\">\n                                            [vc_section el_class=\"container mx-auto align-items-center circle--pattern\" css=\".vc_custom_1648956589196{padding-top: 3rem !important;}\"][vc_row el_class=\"pb-5\"][vc_column][vc_wp_custommenu nav_menu=\"6\"][uoh_breadcrumb_component automatic_breadcrumb=\"true\"][uoh_title_component title_dropdown=\"big\" title_decorator=\"true\"]{{title}}[\/uoh_title_component][vc_column_text css=\"\"][\/vc_column_text][\/vc_column][\/vc_row][\/vc_section][vc_section css=\".vc_custom_1649209804184{background-color: #f6faff !important;}\" el_class=\"p-md-0 pt-md-5\"][vc_row el_class=\"container mx-auto align-items-center p-md-0 pt-5\"][vc_column el_class=\"p-0\"][\/vc_column][\/vc_row][\/vc_section][vc_section css=\".vc_custom_1649210787516{background-color: #f6faff !important;}\" el_class=\"p-md-0 pt-md-5 pb-md-5\"][vc_row el_class=\"container mx-auto align-items-center\"][vc_column][\/vc_column][\/vc_row][\/vc_section]\n                                        <\/div>\n                                    <\/div>\n                                <\/div>\n                            <\/div><div class=\"mt-3\"><i class=\"fas fa-solid fa-user-tag fa-fw me-2\"><\/i><small class=\"text-muted\">Co-Investigador\/a<\/small><\/div><span class=\"caption-field-publish\"><\/span><\/div><\/div><\/div><\/div><\/div><div class=\"  circle--pattern-bottom-large col-sm-12 col-md-12 img-article\"><div class=\"holder-publish col-md-12\" style=\"border-bottom: 1px solid #48A2F9\"><div class=\"content-holder h-100 component-border overflow-hidden row m-0 p-4 aling-items-center\"><ul class=\"p-0 list-style-none\"><li class=\"p-0 ms-1\"><i class=\"fa fa-regular fa-calendar fa-fw ms-1\"><\/i>Abril 2021 - Febrero 2024<\/li><\/ul><div class=\"caption col-12 p-0 col-md-12 row m-0 align-items-center\"><div class=\"px-md-1\"><small class=\"badge rounded-pill fw-semibold\" style=\"background-color:#48A2F9 !important; color:#FFF\">En Ejecuci\u00f3n<\/small>\n                            <div class=\"accordion accordion-flush\" id=\"36965\">\n                                <div class=\"accordion-item\">\n                                    <h3 class=\"my-0 small-space pt-2 title-ss text-decoration-none accordion-header\">\n                                        <a role=\"button\" class=\"bg-transparent p-0\" href=\"\">\n                                            <i class=\"fas fa-solid fa-link fa-fw me-2\"><\/i>\n                                            Characterization of the resistance of indicator bacteria against critical antimicrobials and identification of associated risk factors in healthy dogs from the Metropolitan Region\n                                        <\/a><\/h3>\n                                    <div id=\"collapse-36965\" class=\"accordion-collapse collapse\" data-bs-parent=\"#36965\">\n                                        <div class=\"accordion-body p-0 pt-4 pb-4\">\n                                            [vc_section el_class=\"container mx-auto align-items-center circle--pattern\" css=\".vc_custom_1648956589196{padding-top: 3rem !important;}\"][vc_row el_class=\"pb-5\"][vc_column][vc_wp_custommenu nav_menu=\"6\"][uoh_breadcrumb_component automatic_breadcrumb=\"true\"][uoh_title_component title_dropdown=\"big\" title_decorator=\"true\"]{{title}}[\/uoh_title_component][vc_column_text css=\"\"][\/vc_column_text][\/vc_column][\/vc_row][\/vc_section][vc_section css=\".vc_custom_1649209804184{background-color: #f6faff !important;}\" el_class=\"p-md-0 pt-md-5\"][vc_row el_class=\"container mx-auto align-items-center p-md-0 pt-5\"][vc_column el_class=\"p-0\"][\/vc_column][\/vc_row][\/vc_section][vc_section css=\".vc_custom_1649210787516{background-color: #f6faff !important;}\" el_class=\"p-md-0 pt-md-5 pb-md-5\"][vc_row el_class=\"container mx-auto align-items-center\"][vc_column][\/vc_column][\/vc_row][\/vc_section]\n                                        <\/div>\n                                    <\/div>\n                                <\/div>\n                            <\/div><div class=\"mt-3\"><i class=\"fas fa-solid fa-user-tag fa-fw me-2\"><\/i><small class=\"text-muted\">Co-Investigador\/a<\/small><\/div><span class=\"caption-field-publish\"><\/span><\/div><\/div><\/div><\/div><\/div><div class=\"  circle--pattern-bottom-large col-sm-12 col-md-12 img-article\"><div class=\"holder-publish col-md-12\" style=\"border-bottom: 1px solid #EFB956\"><div class=\"content-holder h-100 component-border overflow-hidden row m-0 p-4 aling-items-center\"><ul class=\"p-0 list-style-none\"><li class=\"p-0 ms-1\"><i class=\"fa fa-regular fa-calendar fa-fw ms-1\"><\/i>Abril 2021 - Abril 2024<\/li><\/ul><div class=\"caption col-12 p-0 col-md-12 row m-0 align-items-center\"><div class=\"px-md-1\"><small class=\"badge rounded-pill fw-semibold\" style=\"background-color:#EFB956 !important; color:#FFF\">Adjudicado<\/small>\n                            <div class=\"accordion accordion-flush\" id=\"37005\">\n                                <div class=\"accordion-item\">\n                                    <h3 class=\"my-0 small-space pt-2 title-ss text-decoration-none accordion-header\">\n                                        <a role=\"button\" class=\"bg-transparent p-0\" href=\"\">\n                                            <i class=\"fas fa-solid fa-link fa-fw me-2\"><\/i>\n                                            Effects of eccentric, concentric and eccentric\/concentric training on muscle function and mass, functional performance, cardiometabolic health, quality of life and molecular adaptations of skeletal muscle in COPD patients: a multicenter randomized trial\n                                        <\/a><\/h3>\n                                    <div id=\"collapse-37005\" class=\"accordion-collapse collapse\" data-bs-parent=\"#37005\">\n                                        <div class=\"accordion-body p-0 pt-4 pb-4\">\n                                            [vc_section el_class=\"container mx-auto align-items-center circle--pattern\" css=\".vc_custom_1648956589196{padding-top: 3rem !important;}\"][vc_row el_class=\"pb-5\"][vc_column][vc_wp_custommenu nav_menu=\"6\"][uoh_breadcrumb_component automatic_breadcrumb=\"true\"][uoh_title_component title_dropdown=\"big\" title_decorator=\"true\"]{{title}}[\/uoh_title_component][vc_column_text css=\"\"][\/vc_column_text][\/vc_column][\/vc_row][\/vc_section][vc_section css=\".vc_custom_1649209804184{background-color: #f6faff !important;}\" el_class=\"p-md-0 pt-md-5\"][vc_row el_class=\"container mx-auto align-items-center p-md-0 pt-5\"][vc_column el_class=\"p-0\"][\/vc_column][\/vc_row][\/vc_section][vc_section css=\".vc_custom_1649210787516{background-color: #f6faff !important;}\" el_class=\"p-md-0 pt-md-5 pb-md-5\"][vc_row el_class=\"container mx-auto align-items-center\"][vc_column][\/vc_column][\/vc_row][\/vc_section]\n                                        <\/div>\n                                    <\/div>\n                                <\/div>\n                            <\/div><div class=\"mt-3\"><i class=\"fas fa-solid fa-user-tag fa-fw me-2\"><\/i><small class=\"text-muted\">Co-Investigador\/a<\/small><\/div><span class=\"caption-field-publish\"><\/span><\/div><\/div><\/div><\/div><\/div><div class=\"  circle--pattern-bottom-large col-sm-12 col-md-12 img-article\"><div class=\"holder-publish col-md-12\" style=\"border-bottom: 1px solid #48A2F9\"><div class=\"content-holder h-100 component-border overflow-hidden row m-0 p-4 aling-items-center\"><ul class=\"p-0 list-style-none\"><li class=\"p-0 ms-1\"><i class=\"fa fa-regular fa-calendar fa-fw ms-1\"><\/i>Abril 2021 - Marzo 2023<\/li><\/ul><div class=\"caption col-12 p-0 col-md-12 row m-0 align-items-center\"><div class=\"px-md-1\"><small class=\"badge rounded-pill fw-semibold\" style=\"background-color:#48A2F9 !important; color:#FFF\">En Ejecuci\u00f3n<\/small>\n                            <div class=\"accordion accordion-flush\" id=\"37028\">\n                                <div class=\"accordion-item\">\n                                    <h3 class=\"my-0 small-space pt-2 title-ss text-decoration-none accordion-header\">\n                                        <a role=\"button\" class=\"bg-transparent p-0\" href=\"\">\n                                            <i class=\"fas fa-solid fa-link fa-fw me-2\"><\/i>\n                                            Transferencia Drosophila suzukii: Plaga presente &#8211; Futura convivencia\n                                        <\/a><\/h3>\n                                    <div id=\"collapse-37028\" class=\"accordion-collapse collapse\" data-bs-parent=\"#37028\">\n                                        <div class=\"accordion-body p-0 pt-4 pb-4\">\n                                            [vc_section el_class=\"container mx-auto align-items-center circle--pattern\" css=\".vc_custom_1648956589196{padding-top: 3rem !important;}\"][vc_row el_class=\"pb-5\"][vc_column][vc_wp_custommenu nav_menu=\"6\"][uoh_breadcrumb_component automatic_breadcrumb=\"true\"][uoh_title_component title_dropdown=\"big\" title_decorator=\"true\"]{{title}}[\/uoh_title_component][vc_column_text css=\"\"][\/vc_column_text][\/vc_column][\/vc_row][\/vc_section][vc_section css=\".vc_custom_1649209804184{background-color: #f6faff !important;}\" el_class=\"p-md-0 pt-md-5\"][vc_row el_class=\"container mx-auto align-items-center p-md-0 pt-5\"][vc_column el_class=\"p-0\"][\/vc_column][\/vc_row][\/vc_section][vc_section css=\".vc_custom_1649210787516{background-color: #f6faff !important;}\" el_class=\"p-md-0 pt-md-5 pb-md-5\"][vc_row el_class=\"container mx-auto align-items-center\"][vc_column][\/vc_column][\/vc_row][\/vc_section]\n                                        <\/div>\n                                    <\/div>\n                                <\/div>\n                            <\/div><div class=\"mt-3\"><i class=\"fas fa-solid fa-user-tag fa-fw me-2\"><\/i><small class=\"text-muted\">Investigador\/a Responsable<\/small><\/div><span class=\"caption-field-publish\"><\/span><\/div><\/div><\/div><\/div><\/div><div class=\"  circle--pattern-bottom-large col-sm-12 col-md-12 img-article\"><div class=\"holder-publish col-md-12\" style=\"border-bottom: 1px solid #35DB54\"><div class=\"content-holder h-100 component-border overflow-hidden row m-0 p-4 aling-items-center\"><ul class=\"p-0 list-style-none\"><li class=\"p-0 ms-1\"><i class=\"fa fa-regular fa-calendar fa-fw ms-1\"><\/i>Diciembre 2020 - Marzo 2022<\/li><\/ul><div class=\"caption col-12 p-0 col-md-12 row m-0 align-items-center\"><div class=\"px-md-1\"><small class=\"badge rounded-pill fw-semibold\" style=\"background-color:#35DB54 !important; color:#FFF\">Finalizado<\/small><small class=\"ms-2 badge rounded-pill fw-semibold\" style=\"background-color:#F0F1F3 !important; color:#797979\"><i class=\"fa fa-solid fa-lg fa-money-check-dollar fa-fw me-1\"><\/i>Agencia Nacional de Investigaci\u00f3n y Desarrollo - ANID<\/small>\n                            <div class=\"accordion accordion-flush\" id=\"36967\">\n                                <div class=\"accordion-item\">\n                                    <h3 class=\"my-0 small-space pt-2 title-ss text-decoration-none accordion-header\">\n                                        <a role=\"button\" class=\"bg-transparent p-0\" href=\"\">\n                                            <i class=\"fas fa-solid fa-link fa-fw me-2\"><\/i>\n                                            Generaci\u00f3n de capital social entre los productores ap\u00edcolas y la universidad de O\u0092Higgins, para mejorar el estatus sanitario y epidemiol\u00f3gico de las colmenas de la regi\u00f3n de O\u0092Higgins\n                                        <\/a><\/h3>\n                                    <div id=\"collapse-36967\" class=\"accordion-collapse collapse\" data-bs-parent=\"#36967\">\n                                        <div class=\"accordion-body p-0 pt-4 pb-4\">\n                                            [vc_section el_class=\"container mx-auto align-items-center circle--pattern\" css=\".vc_custom_1648956589196{padding-top: 3rem !important;}\"][vc_row el_class=\"pb-5\"][vc_column][vc_wp_custommenu nav_menu=\"6\"][uoh_breadcrumb_component automatic_breadcrumb=\"true\"][uoh_title_component title_dropdown=\"big\" title_decorator=\"true\"]{{title}}[\/uoh_title_component][vc_column_text css=\"\"]El objetivo es dise\u00f1ar e implementar una estrategia transdisciplinaria de vinculaci\u00f3n entre los apicultores de la regi\u00f3n y la Universidad de O'Higgins, que permita construir una \u0093Hoja de Ruta\u0094 para resolver las brechas existentes en el sector y definir las l\u00edneas de investigaci\u00f3n aplicada a desarrollarse. Esto permitir\u00e1 mejorar la asociatividad de los apicultores, mejorar la salud de las colmenas, los servicios de polinizaci\u00f3n y por ende la productividad ap\u00edcola regional.[\/vc_column_text][\/vc_column][\/vc_row][\/vc_section][vc_section css=\".vc_custom_1649209804184{background-color: #f6faff !important;}\" el_class=\"p-md-0 pt-md-5\"][vc_row el_class=\"container mx-auto align-items-center p-md-0 pt-5\"][vc_column el_class=\"p-0\"][\/vc_column][\/vc_row][\/vc_section][vc_section css=\".vc_custom_1649210787516{background-color: #f6faff !important;}\" el_class=\"p-md-0 pt-md-5 pb-md-5\"][vc_row el_class=\"container mx-auto align-items-center\"][vc_column][\/vc_column][\/vc_row][\/vc_section]\n                                        <\/div>\n                                    <\/div>\n                                <\/div>\n                            <\/div><div class=\"mt-3\"><i class=\"fas fa-solid fa-user-tag fa-fw me-2\"><\/i><small class=\"text-muted\">Co-Investigador\/a<\/small><\/div><span class=\"caption-field-publish\"><\/span><\/div><\/div><\/div><\/div><\/div><div class=\"  circle--pattern-bottom-large col-sm-12 col-md-12 img-article\"><div class=\"holder-publish col-md-12\" style=\"border-bottom: 1px solid #35DB54\"><div class=\"content-holder h-100 component-border overflow-hidden row m-0 p-4 aling-items-center\"><ul class=\"p-0 list-style-none\"><li class=\"p-0 ms-1\"><i class=\"fa fa-regular fa-calendar fa-fw ms-1\"><\/i>Julio 2020 - Marzo 2021<\/li><\/ul><div class=\"caption col-12 p-0 col-md-12 row m-0 align-items-center\"><div class=\"px-md-1\"><small class=\"badge rounded-pill fw-semibold\" style=\"background-color:#35DB54 !important; color:#FFF\">Finalizado<\/small><small class=\"ms-2 badge rounded-pill fw-semibold\" style=\"background-color:#F0F1F3 !important; color:#797979\"><i class=\"fa fa-solid fa-lg fa-money-check-dollar fa-fw me-1\"><\/i>Agencia Nacional de Investigaci\u00f3n y Desarrollo - ANID<\/small>\n                            <div class=\"accordion accordion-flush\" id=\"36969\">\n                                <div class=\"accordion-item\">\n                                    <h3 class=\"my-0 small-space pt-2 title-ss text-decoration-none accordion-header\">\n                                        <a role=\"button\" class=\"bg-transparent p-0\" href=\"\">\n                                            <i class=\"fas fa-solid fa-link fa-fw me-2\"><\/i>\n                                            Estudio epidemiol\u00f3gico observacional para evaluar el efecto de medidas de control gubernamentales sobre la din\u00e1mica espacio-temporal de Covid-19 en Chile\n                                        <\/a><\/h3>\n                                    <div id=\"collapse-36969\" class=\"accordion-collapse collapse\" data-bs-parent=\"#36969\">\n                                        <div class=\"accordion-body p-0 pt-4 pb-4\">\n                                            [vc_section el_class=\"container mx-auto align-items-center circle--pattern\" css=\".vc_custom_1648956589196{padding-top: 3rem !important;}\"][vc_row el_class=\"pb-5\"][vc_column][vc_wp_custommenu nav_menu=\"6\"][uoh_breadcrumb_component automatic_breadcrumb=\"true\"][uoh_title_component title_dropdown=\"big\" title_decorator=\"true\"]{{title}}[\/uoh_title_component][vc_column_text css=\"\"]A\u00fan lejos de tener una vacuna efectiva y segura, los gobiernos nacionales han tenido que establecer medidas sanitarias (e.g. cuarentena) para reducir el impacto de la pandemia de COVID-19. Sin embargo, no existe claridad respecto a cu\u00e1les medidas son las m\u00e1s eficaces y c\u00f3mo la efectividad de \u00e9stas es afectada por diferentes contextos sociales, demogr\u00e1ficos y epidemiol\u00f3gicos. El objetivo de esta propuesta es desarrollar un estudio observacional para evaluar el impacto de las diferentes medidas de control aplicadas por la autoridad sanitaria sobre la din\u00e1mica de COVID-19, a nivel comunal y de \u00e1reas metropolitanas, utilizando la informaci\u00f3n generada por el Ministerio de Salud. Los datos ser\u00e1n analizados utilizando modelos de regresi\u00f3n para datos de conteo, lo que permitir\u00e1 evaluar potenciales desfases en el tiempo de los efectos de las medidas de control, junto con considerar el efecto de variables potencialmente confundentes. Al finalizar este estudio, la autoridad sanitaria dispondr\u00e1 de evidencia cient\u00edfica para sustentar el establecimiento de diferentes medidas de control para COVID-19, dependiendo de contextos sociales, demogr\u00e1ficos y epidemiol\u00f3gicos, permitiendo enfatizar aquellas medidas m\u00e1s adecuadas para cada caso. Los modelos quedar\u00e1n disponibles en una aplicaci\u00f3n web donde podr\u00e1n ser interrogados por las autoridades sanitarias.[\/vc_column_text][\/vc_column][\/vc_row][\/vc_section][vc_section css=\".vc_custom_1649209804184{background-color: #f6faff !important;}\" el_class=\"p-md-0 pt-md-5\"][vc_row el_class=\"container mx-auto align-items-center p-md-0 pt-5\"][vc_column el_class=\"p-0\"][\/vc_column][\/vc_row][\/vc_section][vc_section css=\".vc_custom_1649210787516{background-color: #f6faff !important;}\" el_class=\"p-md-0 pt-md-5 pb-md-5\"][vc_row el_class=\"container mx-auto align-items-center\"][vc_column][\/vc_column][\/vc_row][\/vc_section]\n                                        <\/div>\n                                    <\/div>\n                                <\/div>\n                            <\/div><div class=\"mt-3\"><i class=\"fas fa-solid fa-user-tag fa-fw me-2\"><\/i><small class=\"text-muted\">Investigador\/a Responsable<\/small><\/div><span class=\"caption-field-publish\"><\/span><\/div><\/div><\/div><\/div><\/div><div class=\"  circle--pattern-bottom-large col-sm-12 col-md-12 img-article\"><div class=\"holder-publish col-md-12\" style=\"border-bottom: 1px solid #35DB54\"><div class=\"content-holder h-100 component-border overflow-hidden row m-0 p-4 aling-items-center\"><ul class=\"p-0 list-style-none\"><li class=\"p-0 ms-1\"><i class=\"fa fa-regular fa-calendar fa-fw ms-1\"><\/i>Abril 2020 - Marzo 2023<\/li><\/ul><div class=\"caption col-12 p-0 col-md-12 row m-0 align-items-center\"><div class=\"px-md-1\"><small class=\"badge rounded-pill fw-semibold\" style=\"background-color:#35DB54 !important; color:#FFF\">Finalizado<\/small><small class=\"ms-2 badge rounded-pill fw-semibold\" style=\"background-color:#F0F1F3 !important; color:#797979\"><i class=\"fa fa-solid fa-lg fa-money-check-dollar fa-fw me-1\"><\/i>Gobierno Regional - GORE<\/small>\n                            <div class=\"accordion accordion-flush\" id=\"36970\">\n                                <div class=\"accordion-item\">\n                                    <h3 class=\"my-0 small-space pt-2 title-ss text-decoration-none accordion-header\">\n                                        <a role=\"button\" class=\"bg-transparent p-0\" href=\"\">\n                                            <i class=\"fas fa-solid fa-link fa-fw me-2\"><\/i>\n                                            Transferencia de  un Modelo de Inocuidad agroalimentaria regional\n                                        <\/a><\/h3>\n                                    <div id=\"collapse-36970\" class=\"accordion-collapse collapse\" data-bs-parent=\"#36970\">\n                                        <div class=\"accordion-body p-0 pt-4 pb-4\">\n                                            [vc_section el_class=\"container mx-auto align-items-center circle--pattern\" css=\".vc_custom_1648956589196{padding-top: 3rem !important;}\"][vc_row el_class=\"pb-5\"][vc_column][vc_wp_custommenu nav_menu=\"6\"][uoh_breadcrumb_component automatic_breadcrumb=\"true\"][uoh_title_component title_dropdown=\"big\" title_decorator=\"true\"]{{title}}[\/uoh_title_component][vc_column_text css=\"\"]Este proyecto tiene como objetivo, ejecutar un sistema de extensi\u00f3n para productores hort\u00edcolas y ap\u00edcolas de la regi\u00f3n de O\u0092Higgins, junto con un sistema de monitoreo de peligros alimentarios, un sistema de cultura de inocuidad y un SELLO o marca de certificaci\u00f3n en base a criterios de inocuidad alimentaria.[\/vc_column_text][\/vc_column][\/vc_row][\/vc_section][vc_section css=\".vc_custom_1649209804184{background-color: #f6faff !important;}\" el_class=\"p-md-0 pt-md-5\"][vc_row el_class=\"container mx-auto align-items-center p-md-0 pt-5\"][vc_column el_class=\"p-0\"][\/vc_column][\/vc_row][\/vc_section][vc_section css=\".vc_custom_1649210787516{background-color: #f6faff !important;}\" el_class=\"p-md-0 pt-md-5 pb-md-5\"][vc_row el_class=\"container mx-auto align-items-center\"][vc_column][\/vc_column][\/vc_row][\/vc_section]\n                                        <\/div>\n                                    <\/div>\n                                <\/div>\n                            <\/div><div class=\"mt-3\"><i class=\"fas fa-solid fa-user-tag fa-fw me-2\"><\/i><small class=\"text-muted\">Co-Investigador\/a<\/small><\/div><span class=\"caption-field-publish\"><\/span><\/div><\/div><\/div><\/div><\/div><div class=\"  circle--pattern-bottom-large col-sm-12 col-md-12 img-article\"><div class=\"holder-publish col-md-12\" style=\"border-bottom: 1px solid #35DB54\"><div class=\"content-holder h-100 component-border overflow-hidden row m-0 p-4 aling-items-center\"><ul class=\"p-0 list-style-none\"><li class=\"p-0 ms-1\"><i class=\"fa fa-regular fa-calendar fa-fw ms-1\"><\/i>Abril 2020 - Febrero 2022<\/li><\/ul><div class=\"caption col-12 p-0 col-md-12 row m-0 align-items-center\"><div class=\"px-md-1\"><small class=\"badge rounded-pill fw-semibold\" style=\"background-color:#35DB54 !important; color:#FFF\">Finalizado<\/small>\n                            <div class=\"accordion accordion-flush\" id=\"37029\">\n                                <div class=\"accordion-item\">\n                                    <h3 class=\"my-0 small-space pt-2 title-ss text-decoration-none accordion-header\">\n                                        <a role=\"button\" class=\"bg-transparent p-0\" href=\"\">\n                                            <i class=\"fas fa-solid fa-link fa-fw me-2\"><\/i>\n                                            Image Modeling and Processing for REmote SenSing in agriculture (IMPRESS)\n                                        <\/a><\/h3>\n                                    <div id=\"collapse-37029\" class=\"accordion-collapse collapse\" data-bs-parent=\"#37029\">\n                                        <div class=\"accordion-body p-0 pt-4 pb-4\">\n                                            [vc_section el_class=\"container mx-auto align-items-center circle--pattern\" css=\".vc_custom_1648956589196{padding-top: 3rem !important;}\"][vc_row el_class=\"pb-5\"][vc_column][vc_wp_custommenu nav_menu=\"6\"][uoh_breadcrumb_component automatic_breadcrumb=\"true\"][uoh_title_component title_dropdown=\"big\" title_decorator=\"true\"]{{title}}[\/uoh_title_component][vc_column_text css=\"\"]The field of remote sensing is experiencing an unprecedented acceleration. Besides the large public programs such as Sentinel (see e.g. https:\/\/sentinel.esa.int\/web\/sentinel\/missions\/sentinel-2), private actors are creating fleets of micro-satellites capable of  monitoring of the earth with daily revisits. This abundant and cheap data is creating opportunities for developing novel applications for the monitoring of industrial and agricultural activity. The automatic exploitation of this data is bound to specific application domain knowledge, which  requires a mastery of advanced techniques such as computer vision and machine learning, as well as expert knowledge in the field of agriculture. To do this, the team must master earth observation satellites, be able to define the adequate mathematical detection theories, and build on a deep knowledge of satellite image processing, while also including expert knowledge in agriculture. This project aims at uniting competences across the fields of computer vision and machine learning, remote sensing to address emerging applications in agronomy. This project will in addition foster the creation of reproducible research by adopting a reproducible research methodology thus contributing the resulting algorithms to the journal Image Processing On-Line (IPOL). The IPOL journal is an initiative to establish a clear and reproducible state-of-the-art in the domain of image processing and computer vision.[\/vc_column_text][\/vc_column][\/vc_row][\/vc_section][vc_section css=\".vc_custom_1649209804184{background-color: #f6faff !important;}\" el_class=\"p-md-0 pt-md-5\"][vc_row el_class=\"container mx-auto align-items-center p-md-0 pt-5\"][vc_column el_class=\"p-0\"][\/vc_column][\/vc_row][\/vc_section][vc_section css=\".vc_custom_1649210787516{background-color: #f6faff !important;}\" el_class=\"p-md-0 pt-md-5 pb-md-5\"][vc_row el_class=\"container mx-auto align-items-center\"][vc_column][\/vc_column][\/vc_row][\/vc_section]\n                                        <\/div>\n                                    <\/div>\n                                <\/div>\n                            <\/div><div class=\"mt-3\"><i class=\"fas fa-solid fa-user-tag fa-fw me-2\"><\/i><small class=\"text-muted\">Co-Investigador\/a<\/small><\/div><span class=\"caption-field-publish\"><\/span><\/div><\/div><\/div><\/div><\/div><div class=\"  circle--pattern-bottom-large col-sm-12 col-md-12 img-article\"><div class=\"holder-publish col-md-12\" style=\"border-bottom: 1px solid #35DB54\"><div class=\"content-holder h-100 component-border overflow-hidden row m-0 p-4 aling-items-center\"><ul class=\"p-0 list-style-none\"><li class=\"p-0 ms-1\"><i class=\"fa fa-regular fa-calendar fa-fw ms-1\"><\/i>Noviembre 2019 - Octubre 2022<\/li><\/ul><div class=\"caption col-12 p-0 col-md-12 row m-0 align-items-center\"><div class=\"px-md-1\"><small class=\"badge rounded-pill fw-semibold\" style=\"background-color:#35DB54 !important; color:#FFF\">Finalizado<\/small><small class=\"ms-2 badge rounded-pill fw-semibold\" style=\"background-color:#F0F1F3 !important; color:#797979\"><i class=\"fa fa-solid fa-lg fa-money-check-dollar fa-fw me-1\"><\/i>Agencia Nacional de Investigaci\u00f3n y Desarrollo - ANID<\/small>\n                            <div class=\"accordion accordion-flush\" id=\"37009\">\n                                <div class=\"accordion-item\">\n                                    <h3 class=\"my-0 small-space pt-2 title-ss text-decoration-none accordion-header\">\n                                        <a role=\"button\" class=\"bg-transparent p-0\" href=\"\">\n                                            <i class=\"fas fa-solid fa-link fa-fw me-2\"><\/i>\n                                            Exercise stimulates autophagy by downregulation of NOX2 activity improving young and aged human skeletal muscle function\n                                        <\/a><\/h3>\n                                    <div id=\"collapse-37009\" class=\"accordion-collapse collapse\" data-bs-parent=\"#37009\">\n                                        <div class=\"accordion-body p-0 pt-4 pb-4\">\n                                            [vc_section el_class=\"container mx-auto align-items-center circle--pattern\" css=\".vc_custom_1648956589196{padding-top: 3rem !important;}\"][vc_row el_class=\"pb-5\"][vc_column][vc_wp_custommenu nav_menu=\"6\"][uoh_breadcrumb_component automatic_breadcrumb=\"true\"][uoh_title_component title_dropdown=\"big\" title_decorator=\"true\"]{{title}}[\/uoh_title_component][vc_column_text css=\"\"]During the past few decades average life expectancy has dramatically increased worldwide; specifically by 2050 the number of older adults will overcome the number of young people in Chile. This leads to a major challenge due to multiple chronic diseases highly prevalent in elderly. Aging process is defined as a series of time-dependent physiological changes that decrease reserve and functional capacity of skeletal muscle. Several studies have proposed that aging is caused by damage of macromolecules by reactive oxygen species (ROS) and decreased autophagy levels, a process that is essential for skeletal muscle regeneration, homeostasis and function. Exercise is a novel strategy used in elderly, which has shown to improve muscle mass, muscle function and decrease chronic diseases in old individuals. However, the molecular mechanisms and signaling pathways involved on the benefits of exercise in aged skeletal muscle are not completely clear. While exercise regulations of oxidative stress and autophagy have been studied separately, a direct interplay between exercise inducing autophagy via a ROS-dependent pathway has not yet been addressed in young or aged human skeletal muscle. Moreover, studies in human skeletal muscle examining the autophagy modulation after endurance exercise are limited and controversial. Although it is known that resting autophagy levels are decreased in aged skeletal muscle, the effects of acute exercise on skeletal muscle autophagy between young and older adults remain to be elucidated and could shed light on regulation of autophagy in humans. Additionally, it is also not known if a controlled exercise-training program can induce similar increases in autophagy levels in older adults. Recently, we have shown that the non-mitochondrial sources of ROS, NADPH oxidases 2 (NOX2), plays a major role in ROS production in skeletal muscle, both at rest and during contracting activity. Furthermore, our preliminary results show that NOX2 expression is increased during the aging process and strongly correlates with decreased autophagy levels detected in aged human skeletal muscle. Moreover, we also show that 12 weeks of endurance exercise training reduced the NOX2 levels in aged human muscle. We speculate that a decrease in NOX2 associated with a decrease in ROS levels in aged skeletal muscle induced by exercise training will improve aged muscle function by re-stablishing autophagy up to young skeletal muscle levels[\/vc_column_text][\/vc_column][\/vc_row][\/vc_section][vc_section css=\".vc_custom_1649209804184{background-color: #f6faff !important;}\" el_class=\"p-md-0 pt-md-5\"][vc_row el_class=\"container mx-auto align-items-center p-md-0 pt-5\"][vc_column el_class=\"p-0\"][\/vc_column][\/vc_row][\/vc_section][vc_section css=\".vc_custom_1649210787516{background-color: #f6faff !important;}\" el_class=\"p-md-0 pt-md-5 pb-md-5\"][vc_row el_class=\"container mx-auto align-items-center\"][vc_column][\/vc_column][\/vc_row][\/vc_section]\n                                        <\/div>\n                                    <\/div>\n                                <\/div>\n                            <\/div><div class=\"mt-3\"><i class=\"fas fa-solid fa-user-tag fa-fw me-2\"><\/i><small class=\"text-muted\">Investigador\/a Responsable<\/small><\/div><span class=\"caption-field-publish\"><\/span><\/div><\/div><\/div><\/div><\/div><div class=\"  circle--pattern-bottom-large col-sm-12 col-md-12 img-article\"><div class=\"holder-publish col-md-12\" style=\"border-bottom: 1px solid #35DB54\"><div class=\"content-holder h-100 component-border overflow-hidden row m-0 p-4 aling-items-center\"><ul class=\"p-0 list-style-none\"><li class=\"p-0 ms-1\"><i class=\"fa fa-regular fa-calendar fa-fw ms-1\"><\/i>Abril 2019 - Marzo 2021<\/li><\/ul><div class=\"caption col-12 p-0 col-md-12 row m-0 align-items-center\"><div class=\"px-md-1\"><small class=\"badge rounded-pill fw-semibold\" style=\"background-color:#35DB54 !important; color:#FFF\">Finalizado<\/small>\n                            <div class=\"accordion accordion-flush\" id=\"37032\">\n                                <div class=\"accordion-item\">\n                                    <h3 class=\"my-0 small-space pt-2 title-ss text-decoration-none accordion-header\">\n                                        <a role=\"button\" class=\"bg-transparent p-0\" href=\"\">\n                                            <i class=\"fas fa-solid fa-link fa-fw me-2\"><\/i>\n                                            Transferencia: D. suzukii mitigaci\u00f3n econ\u00f3mica y social mediante una estrategia de difusi\u00f3n y manejo integrado\n                                        <\/a><\/h3>\n                                    <div id=\"collapse-37032\" class=\"accordion-collapse collapse\" data-bs-parent=\"#37032\">\n                                        <div class=\"accordion-body p-0 pt-4 pb-4\">\n                                            [vc_section el_class=\"container mx-auto align-items-center circle--pattern\" css=\".vc_custom_1648956589196{padding-top: 3rem !important;}\"][vc_row el_class=\"pb-5\"][vc_column][vc_wp_custommenu nav_menu=\"6\"][uoh_breadcrumb_component automatic_breadcrumb=\"true\"][uoh_title_component title_dropdown=\"big\" title_decorator=\"true\"]{{title}}[\/uoh_title_component][vc_column_text css=\"\"]El Objetivo del proyecto es mitigar impacto econ\u00f3mico mediante difusi\u00f3n y capacitaciones taxon\u00f3micas y visuales enfocadas a peque\u00f1os productores, logrando un plan de manejo integrado de la plaga.[\/vc_column_text][\/vc_column][\/vc_row][\/vc_section][vc_section css=\".vc_custom_1649209804184{background-color: #f6faff !important;}\" el_class=\"p-md-0 pt-md-5\"][vc_row el_class=\"container mx-auto align-items-center p-md-0 pt-5\"][vc_column el_class=\"p-0\"][\/vc_column][\/vc_row][\/vc_section][vc_section css=\".vc_custom_1649210787516{background-color: #f6faff !important;}\" el_class=\"p-md-0 pt-md-5 pb-md-5\"][vc_row el_class=\"container mx-auto align-items-center\"][vc_column][\/vc_column][\/vc_row][\/vc_section]\n                                        <\/div>\n                                    <\/div>\n                                <\/div>\n                            <\/div><div class=\"mt-3\"><i class=\"fas fa-solid fa-user-tag fa-fw me-2\"><\/i><small class=\"text-muted\">Investigador\/a Responsable<\/small><\/div><span class=\"caption-field-publish\"><\/span><\/div><\/div><\/div><\/div><\/div><div class=\"  circle--pattern-bottom-large col-sm-12 col-md-12 img-article\"><div class=\"holder-publish col-md-12\" style=\"border-bottom: 1px solid #03286B\"><div class=\"content-holder h-100 component-border overflow-hidden row m-0 p-4 aling-items-center\"><ul class=\"p-0 list-style-none\"><li class=\"p-0 ms-1\"><i class=\"fa fa-regular fa-calendar fa-fw ms-1\"><\/i>Marzo 2018 - Marzo 2020<\/li><\/ul><div class=\"caption col-12 p-0 col-md-12 row m-0 align-items-center\"><div class=\"px-md-1\"><small class=\"badge rounded-pill fw-semibold\" style=\"background-color:#03286B !important; color:#FFF\">Ejecutado<\/small>\n                            <div class=\"accordion accordion-flush\" id=\"37034\">\n                                <div class=\"accordion-item\">\n                                    <h3 class=\"my-0 small-space pt-2 title-ss text-decoration-none accordion-header\">\n                                        <a role=\"button\" class=\"bg-transparent p-0\" href=\"\">\n                                            <i class=\"fas fa-solid fa-link fa-fw me-2\"><\/i>\n                                            Fortalecimiento de la Unidad de An\u00e1lisis Biol\u00f3gicos y Qu\u00edmicos de la Universidad de O\u0092Higgins: Cuantificaci\u00f3n de pesticidas en muestras vegetales y humanas de la regi\u00f3n de O&#8217;Higgins\n                                        <\/a><\/h3>\n                                    <div id=\"collapse-37034\" class=\"accordion-collapse collapse\" data-bs-parent=\"#37034\">\n                                        <div class=\"accordion-body p-0 pt-4 pb-4\">\n                                            [vc_section el_class=\"container mx-auto align-items-center circle--pattern\" css=\".vc_custom_1648956589196{padding-top: 3rem !important;}\"][vc_row el_class=\"pb-5\"][vc_column][vc_wp_custommenu nav_menu=\"6\"][uoh_breadcrumb_component automatic_breadcrumb=\"true\"][uoh_title_component title_dropdown=\"big\" title_decorator=\"true\"]{{title}}[\/uoh_title_component][vc_column_text css=\"\"][\/vc_column_text][\/vc_column][\/vc_row][\/vc_section][vc_section css=\".vc_custom_1649209804184{background-color: #f6faff !important;}\" el_class=\"p-md-0 pt-md-5\"][vc_row el_class=\"container mx-auto align-items-center p-md-0 pt-5\"][vc_column el_class=\"p-0\"][\/vc_column][\/vc_row][\/vc_section][vc_section css=\".vc_custom_1649210787516{background-color: #f6faff !important;}\" el_class=\"p-md-0 pt-md-5 pb-md-5\"][vc_row el_class=\"container mx-auto align-items-center\"][vc_column][\/vc_column][\/vc_row][\/vc_section]\n                                        <\/div>\n                                    <\/div>\n                                <\/div>\n                            <\/div><div class=\"mt-3\"><i class=\"fas fa-solid fa-user-tag fa-fw me-2\"><\/i><small class=\"text-muted\">Co-Investigador\/a<\/small><\/div><span class=\"caption-field-publish\"><\/span><\/div><\/div><\/div><\/div><\/div><div class=\"  circle--pattern-bottom-large col-sm-12 col-md-12 img-article\"><div class=\"holder-publish col-md-12\" style=\"border-bottom: 1px solid #03286B\"><div class=\"content-holder h-100 component-border overflow-hidden row m-0 p-4 aling-items-center\"><ul class=\"p-0 list-style-none\"><li class=\"p-0 ms-1\"><i class=\"fa fa-regular fa-calendar fa-fw ms-1\"><\/i>Octubre 2017 - Noviembre 2018<\/li><\/ul><div class=\"caption col-12 p-0 col-md-12 row m-0 align-items-center\"><div class=\"px-md-1\"><small class=\"badge rounded-pill fw-semibold\" style=\"background-color:#03286B !important; color:#FFF\">Ejecutado<\/small>\n                            <div class=\"accordion accordion-flush\" id=\"36976\">\n                                <div class=\"accordion-item\">\n                                    <h3 class=\"my-0 small-space pt-2 title-ss text-decoration-none accordion-header\">\n                                        <a role=\"button\" class=\"bg-transparent p-0\" href=\"\">\n                                            <i class=\"fas fa-solid fa-link fa-fw me-2\"><\/i>\n                                            Identificaci\u00f3n, ponderaci\u00f3n y validaci\u00f3n en terreno de factores predictivos para el \u00e9xito de tratamientos antiparasitarios por inmersi\u00f3n por medio de un panel de expertos\n                                        <\/a><\/h3>\n                                    <div id=\"collapse-36976\" class=\"accordion-collapse collapse\" data-bs-parent=\"#36976\">\n                                        <div class=\"accordion-body p-0 pt-4 pb-4\">\n                                            [vc_section el_class=\"container mx-auto align-items-center circle--pattern\" css=\".vc_custom_1648956589196{padding-top: 3rem !important;}\"][vc_row el_class=\"pb-5\"][vc_column][vc_wp_custommenu nav_menu=\"6\"][uoh_breadcrumb_component automatic_breadcrumb=\"true\"][uoh_title_component title_dropdown=\"big\" title_decorator=\"true\"]{{title}}[\/uoh_title_component][vc_column_text css=\"\"][\/vc_column_text][\/vc_column][\/vc_row][\/vc_section][vc_section css=\".vc_custom_1649209804184{background-color: #f6faff !important;}\" el_class=\"p-md-0 pt-md-5\"][vc_row el_class=\"container mx-auto align-items-center p-md-0 pt-5\"][vc_column el_class=\"p-0\"][\/vc_column][\/vc_row][\/vc_section][vc_section css=\".vc_custom_1649210787516{background-color: #f6faff !important;}\" el_class=\"p-md-0 pt-md-5 pb-md-5\"][vc_row el_class=\"container mx-auto align-items-center\"][vc_column][\/vc_column][\/vc_row][\/vc_section]\n                                        <\/div>\n                                    <\/div>\n                                <\/div>\n                            <\/div><div class=\"mt-3\"><i class=\"fas fa-solid fa-user-tag fa-fw me-2\"><\/i><small class=\"text-muted\">Co-Investigador\/a<\/small><\/div><span class=\"caption-field-publish\"><\/span><\/div><\/div><\/div><\/div><\/div><div class=\"  circle--pattern-bottom-large col-sm-12 col-md-12 img-article\"><div class=\"holder-publish col-md-12\" style=\"border-bottom: 1px solid #03286B\"><div class=\"content-holder h-100 component-border overflow-hidden row m-0 p-4 aling-items-center\"><ul class=\"p-0 list-style-none\"><li class=\"p-0 ms-1\"><i class=\"fa fa-regular fa-calendar fa-fw ms-1\"><\/i>Marzo 2017 - Diciembre 2019<\/li><\/ul><div class=\"caption col-12 p-0 col-md-12 row m-0 align-items-center\"><div class=\"px-md-1\"><small class=\"badge rounded-pill fw-semibold\" style=\"background-color:#03286B !important; color:#FFF\">Ejecutado<\/small>\n                            <div class=\"accordion accordion-flush\" id=\"36973\">\n                                <div class=\"accordion-item\">\n                                    <h3 class=\"my-0 small-space pt-2 title-ss text-decoration-none accordion-header\">\n                                        <a role=\"button\" class=\"bg-transparent p-0\" href=\"\">\n                                            <i class=\"fas fa-solid fa-link fa-fw me-2\"><\/i>\n                                            CaligusLIFE: Investigaci\u00f3n cient\u00edfica de excelencia para la comprensi\u00f3n de la biolog\u00eda de Caligus rogercresseyi y su aplicaci\u00f3n en estrategias de control de la Caligidosis en la industria del salm\u00f3n\n                                        <\/a><\/h3>\n                                    <div id=\"collapse-36973\" class=\"accordion-collapse collapse\" data-bs-parent=\"#36973\">\n                                        <div class=\"accordion-body p-0 pt-4 pb-4\">\n                                            [vc_section el_class=\"container mx-auto align-items-center circle--pattern\" css=\".vc_custom_1648956589196{padding-top: 3rem !important;}\"][vc_row el_class=\"pb-5\"][vc_column][vc_wp_custommenu nav_menu=\"6\"][uoh_breadcrumb_component automatic_breadcrumb=\"true\"][uoh_title_component title_dropdown=\"big\" title_decorator=\"true\"]{{title}}[\/uoh_title_component][vc_column_text css=\"\"][\/vc_column_text][\/vc_column][\/vc_row][\/vc_section][vc_section css=\".vc_custom_1649209804184{background-color: #f6faff !important;}\" el_class=\"p-md-0 pt-md-5\"][vc_row el_class=\"container mx-auto align-items-center p-md-0 pt-5\"][vc_column el_class=\"p-0\"][\/vc_column][\/vc_row][\/vc_section][vc_section css=\".vc_custom_1649210787516{background-color: #f6faff !important;}\" el_class=\"p-md-0 pt-md-5 pb-md-5\"][vc_row el_class=\"container mx-auto align-items-center\"][vc_column][\/vc_column][\/vc_row][\/vc_section]\n                                        <\/div>\n                                    <\/div>\n                                <\/div>\n                            <\/div><div class=\"mt-3\"><i class=\"fas fa-solid fa-user-tag fa-fw me-2\"><\/i><small class=\"text-muted\">Co-Investigador\/a<\/small><\/div><span class=\"caption-field-publish\"><\/span><\/div><\/div><\/div><\/div><\/div><div class=\"  circle--pattern-bottom-large col-sm-12 col-md-12 img-article\"><div class=\"holder-publish col-md-12\" style=\"border-bottom: 1px solid #03286B\"><div class=\"content-holder h-100 component-border overflow-hidden row m-0 p-4 aling-items-center\"><ul class=\"p-0 list-style-none\"><li class=\"p-0 ms-1\"><i class=\"fa fa-regular fa-calendar fa-fw ms-1\"><\/i>Marzo 2017 - Febrero 2020<\/li><\/ul><div class=\"caption col-12 p-0 col-md-12 row m-0 align-items-center\"><div class=\"px-md-1\"><small class=\"badge rounded-pill fw-semibold\" style=\"background-color:#03286B !important; color:#FFF\">Ejecutado<\/small>\n                            <div class=\"accordion accordion-flush\" id=\"36975\">\n                                <div class=\"accordion-item\">\n                                    <h3 class=\"my-0 small-space pt-2 title-ss text-decoration-none accordion-header\">\n                                        <a role=\"button\" class=\"bg-transparent p-0\" href=\"\">\n                                            <i class=\"fas fa-solid fa-link fa-fw me-2\"><\/i>\n                                            Epidemiolog\u00eda de la co-infecci\u00f3n de Caligus rogercresseyi y Piscirickettsia salmonis en salm\u00f3nidos de cultivo en Chile\n                                        <\/a><\/h3>\n                                    <div id=\"collapse-36975\" class=\"accordion-collapse collapse\" data-bs-parent=\"#36975\">\n                                        <div class=\"accordion-body p-0 pt-4 pb-4\">\n                                            [vc_section el_class=\"container mx-auto align-items-center circle--pattern\" css=\".vc_custom_1648956589196{padding-top: 3rem !important;}\"][vc_row el_class=\"pb-5\"][vc_column][vc_wp_custommenu nav_menu=\"6\"][uoh_breadcrumb_component automatic_breadcrumb=\"true\"][uoh_title_component title_dropdown=\"big\" title_decorator=\"true\"]{{title}}[\/uoh_title_component][vc_column_text css=\"\"][\/vc_column_text][\/vc_column][\/vc_row][\/vc_section][vc_section css=\".vc_custom_1649209804184{background-color: #f6faff !important;}\" el_class=\"p-md-0 pt-md-5\"][vc_row el_class=\"container mx-auto align-items-center p-md-0 pt-5\"][vc_column el_class=\"p-0\"][\/vc_column][\/vc_row][\/vc_section][vc_section css=\".vc_custom_1649210787516{background-color: #f6faff !important;}\" el_class=\"p-md-0 pt-md-5 pb-md-5\"][vc_row el_class=\"container mx-auto align-items-center\"][vc_column][\/vc_column][\/vc_row][\/vc_section]\n                                        <\/div>\n                                    <\/div>\n                                <\/div>\n                            <\/div><div class=\"mt-3\"><i class=\"fas fa-solid fa-user-tag fa-fw me-2\"><\/i><small class=\"text-muted\">Co-Investigador\/a<\/small><\/div><span class=\"caption-field-publish\"><\/span><\/div><\/div><\/div><\/div><\/div><div class=\"  circle--pattern-bottom-large col-sm-12 col-md-12 img-article\"><div class=\"holder-publish col-md-12\" style=\"border-bottom: 1px solid #03286B\"><div class=\"content-holder h-100 component-border overflow-hidden row m-0 p-4 aling-items-center\"><ul class=\"p-0 list-style-none\"><li class=\"p-0 ms-1\"><i class=\"fa fa-regular fa-calendar fa-fw ms-1\"><\/i>Agosto 2015 - Octubre 2016<\/li><\/ul><div class=\"caption col-12 p-0 col-md-12 row m-0 align-items-center\"><div class=\"px-md-1\"><small class=\"badge rounded-pill fw-semibold\" style=\"background-color:#03286B !important; color:#FFF\">Ejecutado<\/small>\n                            <div class=\"accordion accordion-flush\" id=\"36979\">\n                                <div class=\"accordion-item\">\n                                    <h3 class=\"my-0 small-space pt-2 title-ss text-decoration-none accordion-header\">\n                                        <a role=\"button\" class=\"bg-transparent p-0\" href=\"\">\n                                            <i class=\"fas fa-solid fa-link fa-fw me-2\"><\/i>\n                                            Evaluaci\u00f3n bibliogr\u00e1fica y estad\u00edstica de las estrategias estacionales coordinadas de tratamiento contra Caligus rogercresseyi para su optimizaci\u00f3n a trav\u00e9s de un protocolo\n                                        <\/a><\/h3>\n                                    <div id=\"collapse-36979\" class=\"accordion-collapse collapse\" data-bs-parent=\"#36979\">\n                                        <div class=\"accordion-body p-0 pt-4 pb-4\">\n                                            [vc_section el_class=\"container mx-auto align-items-center circle--pattern\" css=\".vc_custom_1648956589196{padding-top: 3rem !important;}\"][vc_row el_class=\"pb-5\"][vc_column][vc_wp_custommenu nav_menu=\"6\"][uoh_breadcrumb_component automatic_breadcrumb=\"true\"][uoh_title_component title_dropdown=\"big\" title_decorator=\"true\"]{{title}}[\/uoh_title_component][vc_column_text css=\"\"][\/vc_column_text][\/vc_column][\/vc_row][\/vc_section][vc_section css=\".vc_custom_1649209804184{background-color: #f6faff !important;}\" el_class=\"p-md-0 pt-md-5\"][vc_row el_class=\"container mx-auto align-items-center p-md-0 pt-5\"][vc_column el_class=\"p-0\"][\/vc_column][\/vc_row][\/vc_section][vc_section css=\".vc_custom_1649210787516{background-color: #f6faff !important;}\" el_class=\"p-md-0 pt-md-5 pb-md-5\"][vc_row el_class=\"container mx-auto align-items-center\"][vc_column][\/vc_column][\/vc_row][\/vc_section]\n                                        <\/div>\n                                    <\/div>\n                                <\/div>\n                            <\/div><div class=\"mt-3\"><i class=\"fas fa-solid fa-user-tag fa-fw me-2\"><\/i><small class=\"text-muted\">Co-Investigador\/a<\/small><\/div><span class=\"caption-field-publish\"><\/span><\/div><\/div><\/div><\/div><\/div><div class=\"  circle--pattern-bottom-large col-sm-12 col-md-12 img-article\"><div class=\"holder-publish col-md-12\" style=\"border-bottom: 1px solid #03286B\"><div class=\"content-holder h-100 component-border overflow-hidden row m-0 p-4 aling-items-center\"><ul class=\"p-0 list-style-none\"><li class=\"p-0 ms-1\"><i class=\"fa fa-regular fa-calendar fa-fw ms-1\"><\/i>Junio 2014 - Noviembre 2015<\/li><\/ul><div class=\"caption col-12 p-0 col-md-12 row m-0 align-items-center\"><div class=\"px-md-1\"><small class=\"badge rounded-pill fw-semibold\" style=\"background-color:#03286B !important; color:#FFF\">Ejecutado<\/small>\n                            <div class=\"accordion accordion-flush\" id=\"36981\">\n                                <div class=\"accordion-item\">\n                                    <h3 class=\"my-0 small-space pt-2 title-ss text-decoration-none accordion-header\">\n                                        <a role=\"button\" class=\"bg-transparent p-0\" href=\"\">\n                                            <i class=\"fas fa-solid fa-link fa-fw me-2\"><\/i>\n                                            Nuevos prototipos de sets de biomarcadores sangu\u00edneos aplicados al diagn\u00f3stico predictivo de enfermedades en acuicultura \u0096 Bioblood y Bioplasma\n                                        <\/a><\/h3>\n                                    <div id=\"collapse-36981\" class=\"accordion-collapse collapse\" data-bs-parent=\"#36981\">\n                                        <div class=\"accordion-body p-0 pt-4 pb-4\">\n                                            [vc_section el_class=\"container mx-auto align-items-center circle--pattern\" css=\".vc_custom_1648956589196{padding-top: 3rem !important;}\"][vc_row el_class=\"pb-5\"][vc_column][vc_wp_custommenu nav_menu=\"6\"][uoh_breadcrumb_component automatic_breadcrumb=\"true\"][uoh_title_component title_dropdown=\"big\" title_decorator=\"true\"]{{title}}[\/uoh_title_component][vc_column_text css=\"\"][\/vc_column_text][\/vc_column][\/vc_row][\/vc_section][vc_section css=\".vc_custom_1649209804184{background-color: #f6faff !important;}\" el_class=\"p-md-0 pt-md-5\"][vc_row el_class=\"container mx-auto align-items-center p-md-0 pt-5\"][vc_column el_class=\"p-0\"][\/vc_column][\/vc_row][\/vc_section][vc_section css=\".vc_custom_1649210787516{background-color: #f6faff !important;}\" el_class=\"p-md-0 pt-md-5 pb-md-5\"][vc_row el_class=\"container mx-auto align-items-center\"][vc_column][\/vc_column][\/vc_row][\/vc_section]\n                                        <\/div>\n                                    <\/div>\n                                <\/div>\n                            <\/div><div class=\"mt-3\"><i class=\"fas fa-solid fa-user-tag fa-fw me-2\"><\/i><small class=\"text-muted\">Co-Investigador\/a<\/small><\/div><span class=\"caption-field-publish\"><\/span><\/div><\/div><\/div><\/div><\/div><div class=\"  circle--pattern-bottom-large col-sm-12 col-md-12 img-article\"><div class=\"holder-publish col-md-12\" style=\"border-bottom: 1px solid #03286B\"><div class=\"content-holder h-100 component-border overflow-hidden row m-0 p-4 aling-items-center\"><ul class=\"p-0 list-style-none\"><li class=\"p-0 ms-1\"><i class=\"fa fa-regular fa-calendar fa-fw ms-1\"><\/i>Octubre 2013 - Octubre 2016<\/li><\/ul><div class=\"caption col-12 p-0 col-md-12 row m-0 align-items-center\"><div class=\"px-md-1\"><small class=\"badge rounded-pill fw-semibold\" style=\"background-color:#03286B !important; color:#FFF\">Ejecutado<\/small>\n                            <div class=\"accordion accordion-flush\" id=\"37011\">\n                                <div class=\"accordion-item\">\n                                    <h3 class=\"my-0 small-space pt-2 title-ss text-decoration-none accordion-header\">\n                                        <a role=\"button\" class=\"bg-transparent p-0\" href=\"\">\n                                            <i class=\"fas fa-solid fa-link fa-fw me-2\"><\/i>\n                                            Modulaci\u00f3n de la autofagia por el receptor de inositol trifosfato (IP3R) en distrofia muscular de Duchenne\n                                        <\/a><\/h3>\n                                    <div id=\"collapse-37011\" class=\"accordion-collapse collapse\" data-bs-parent=\"#37011\">\n                                        <div class=\"accordion-body p-0 pt-4 pb-4\">\n                                            [vc_section el_class=\"container mx-auto align-items-center circle--pattern\" css=\".vc_custom_1648956589196{padding-top: 3rem !important;}\"][vc_row el_class=\"pb-5\"][vc_column][vc_wp_custommenu nav_menu=\"6\"][uoh_breadcrumb_component automatic_breadcrumb=\"true\"][uoh_title_component title_dropdown=\"big\" title_decorator=\"true\"]{{title}}[\/uoh_title_component][vc_column_text css=\"\"][\/vc_column_text][\/vc_column][\/vc_row][\/vc_section][vc_section css=\".vc_custom_1649209804184{background-color: #f6faff !important;}\" el_class=\"p-md-0 pt-md-5\"][vc_row el_class=\"container mx-auto align-items-center p-md-0 pt-5\"][vc_column el_class=\"p-0\"][\/vc_column][\/vc_row][\/vc_section][vc_section css=\".vc_custom_1649210787516{background-color: #f6faff !important;}\" el_class=\"p-md-0 pt-md-5 pb-md-5\"][vc_row el_class=\"container mx-auto align-items-center\"][vc_column][\/vc_column][\/vc_row][\/vc_section]\n                                        <\/div>\n                                    <\/div>\n                                <\/div>\n                            <\/div><div class=\"mt-3\"><i class=\"fas fa-solid fa-user-tag fa-fw me-2\"><\/i><small class=\"text-muted\">Co-Investigador\/a<\/small><\/div><span class=\"caption-field-publish\"><\/span><\/div><\/div><\/div><\/div><\/div><div class=\"  circle--pattern-bottom-large col-sm-12 col-md-12 img-article\"><div class=\"holder-publish col-md-12\" style=\"border-bottom: 1px solid #03286B\"><div class=\"content-holder h-100 component-border overflow-hidden row m-0 p-4 aling-items-center\"><ul class=\"p-0 list-style-none\"><li class=\"p-0 ms-1\"><i class=\"fa fa-regular fa-calendar fa-fw ms-1\"><\/i>Marzo 2009 - Diciembre 2009<\/li><\/ul><div class=\"caption col-12 p-0 col-md-12 row m-0 align-items-center\"><div class=\"px-md-1\"><small class=\"badge rounded-pill fw-semibold\" style=\"background-color:#03286B !important; color:#FFF\">Ejecutado<\/small>\n                            <div class=\"accordion accordion-flush\" id=\"36983\">\n                                <div class=\"accordion-item\">\n                                    <h3 class=\"my-0 small-space pt-2 title-ss text-decoration-none accordion-header\">\n                                        <a role=\"button\" class=\"bg-transparent p-0\" href=\"\">\n                                            <i class=\"fas fa-solid fa-link fa-fw me-2\"><\/i>\n                                            Detecci\u00f3n del virus de la anemia infecciosa del Salm\u00f3n (ISAV) y de la enfermedad pancre\u00e1tica (PDV) en peces silvestres y asilvestrados de lagos de la Regi\u00f3n de Los Lagos con concesiones de acuicultura\n                                        <\/a><\/h3>\n                                    <div id=\"collapse-36983\" class=\"accordion-collapse collapse\" data-bs-parent=\"#36983\">\n                                        <div class=\"accordion-body p-0 pt-4 pb-4\">\n                                            [vc_section el_class=\"container mx-auto align-items-center circle--pattern\" css=\".vc_custom_1648956589196{padding-top: 3rem !important;}\"][vc_row el_class=\"pb-5\"][vc_column][vc_wp_custommenu nav_menu=\"6\"][uoh_breadcrumb_component automatic_breadcrumb=\"true\"][uoh_title_component title_dropdown=\"big\" title_decorator=\"true\"]{{title}}[\/uoh_title_component][vc_column_text css=\"\"][\/vc_column_text][\/vc_column][\/vc_row][\/vc_section][vc_section css=\".vc_custom_1649209804184{background-color: #f6faff !important;}\" el_class=\"p-md-0 pt-md-5\"][vc_row el_class=\"container mx-auto align-items-center p-md-0 pt-5\"][vc_column el_class=\"p-0\"][\/vc_column][\/vc_row][\/vc_section][vc_section css=\".vc_custom_1649210787516{background-color: #f6faff !important;}\" el_class=\"p-md-0 pt-md-5 pb-md-5\"][vc_row el_class=\"container mx-auto align-items-center\"][vc_column][\/vc_column][\/vc_row][\/vc_section]\n                                        <\/div>\n                                    <\/div>\n                                <\/div>\n                            <\/div><div class=\"mt-3\"><i class=\"fas fa-solid fa-user-tag fa-fw me-2\"><\/i><small class=\"text-muted\">Co-Investigador\/a<\/small><\/div><span class=\"caption-field-publish\"><\/span><\/div><\/div><\/div><\/div><\/div><div class=\"  circle--pattern-bottom-large col-sm-12 col-md-12 img-article\"><div class=\"holder-publish col-md-12\" style=\"border-bottom: 1px solid #03286B\"><div class=\"content-holder h-100 component-border overflow-hidden row m-0 p-4 aling-items-center\"><ul class=\"p-0 list-style-none\"><li class=\"p-0 ms-1\"><i class=\"fa fa-regular fa-calendar fa-fw ms-1\"><\/i>Enero 2004 - Diciembre 2005<\/li><\/ul><div class=\"caption col-12 p-0 col-md-12 row m-0 align-items-center\"><div class=\"px-md-1\"><small class=\"badge rounded-pill fw-semibold\" style=\"background-color:#03286B !important; color:#FFF\">Ejecutado<\/small>\n                            <div class=\"accordion accordion-flush\" id=\"36985\">\n                                <div class=\"accordion-item\">\n                                    <h3 class=\"my-0 small-space pt-2 title-ss text-decoration-none accordion-header\">\n                                        <a role=\"button\" class=\"bg-transparent p-0\" href=\"\">\n                                            <i class=\"fas fa-solid fa-link fa-fw me-2\"><\/i>\n                                            Investigaci\u00f3n, Tecnolog\u00edas de la Informaci\u00f3n y Capacitaci\u00f3n Local para apoyar la Toma de Decisiones sanitarias en Mareas Rojas\n                                        <\/a><\/h3>\n                                    <div id=\"collapse-36985\" class=\"accordion-collapse collapse\" data-bs-parent=\"#36985\">\n                                        <div class=\"accordion-body p-0 pt-4 pb-4\">\n                                            [vc_section el_class=\"container mx-auto align-items-center circle--pattern\" css=\".vc_custom_1648956589196{padding-top: 3rem !important;}\"][vc_row el_class=\"pb-5\"][vc_column][vc_wp_custommenu nav_menu=\"6\"][uoh_breadcrumb_component automatic_breadcrumb=\"true\"][uoh_title_component title_dropdown=\"big\" title_decorator=\"true\"]{{title}}[\/uoh_title_component][vc_column_text css=\"\"][\/vc_column_text][\/vc_column][\/vc_row][\/vc_section][vc_section css=\".vc_custom_1649209804184{background-color: #f6faff !important;}\" el_class=\"p-md-0 pt-md-5\"][vc_row el_class=\"container mx-auto align-items-center p-md-0 pt-5\"][vc_column el_class=\"p-0\"][\/vc_column][\/vc_row][\/vc_section][vc_section css=\".vc_custom_1649210787516{background-color: #f6faff !important;}\" el_class=\"p-md-0 pt-md-5 pb-md-5\"][vc_row el_class=\"container mx-auto align-items-center\"][vc_column][\/vc_column][\/vc_row][\/vc_section]\n                                        <\/div>\n                                    <\/div>\n                                <\/div>\n                            <\/div><div class=\"mt-3\"><i class=\"fas fa-solid fa-user-tag fa-fw me-2\"><\/i><small class=\"text-muted\">Co-Investigador\/a<\/small><\/div><span class=\"caption-field-publish\"><\/span><\/div><\/div><\/div><\/div><\/div><div class=\"  circle--pattern-bottom-large col-sm-12 col-md-12 img-article\"><div class=\"holder-publish col-md-12\" style=\"border-bottom: 1px solid #03286B\"><div class=\"content-holder h-100 component-border overflow-hidden row m-0 p-4 aling-items-center\"><ul class=\"p-0 list-style-none\"><li class=\"p-0 ms-1\"><i class=\"fa fa-regular fa-calendar fa-fw ms-1\"><\/i>Enero 2003 - Diciembre 2004<\/li><\/ul><div class=\"caption col-12 p-0 col-md-12 row m-0 align-items-center\"><div class=\"px-md-1\"><small class=\"badge rounded-pill fw-semibold\" style=\"background-color:#03286B !important; color:#FFF\">Ejecutado<\/small>\n                            <div class=\"accordion accordion-flush\" id=\"36987\">\n                                <div class=\"accordion-item\">\n                                    <h3 class=\"my-0 small-space pt-2 title-ss text-decoration-none accordion-header\">\n                                        <a role=\"button\" class=\"bg-transparent p-0\" href=\"\">\n                                            <i class=\"fas fa-solid fa-link fa-fw me-2\"><\/i>\n                                            An\u00e1lisis de riesgos de la operaci\u00f3n de viveros flotantes y barcos de transporte de peces vivos de salm\u00f3nidos\n                                        <\/a><\/h3>\n                                    <div id=\"collapse-36987\" class=\"accordion-collapse collapse\" data-bs-parent=\"#36987\">\n                                        <div class=\"accordion-body p-0 pt-4 pb-4\">\n                                            [vc_section el_class=\"container mx-auto align-items-center circle--pattern\" css=\".vc_custom_1648956589196{padding-top: 3rem !important;}\"][vc_row el_class=\"pb-5\"][vc_column][vc_wp_custommenu nav_menu=\"6\"][uoh_breadcrumb_component automatic_breadcrumb=\"true\"][uoh_title_component title_dropdown=\"big\" title_decorator=\"true\"]{{title}}[\/uoh_title_component][vc_column_text css=\"\"][\/vc_column_text][\/vc_column][\/vc_row][\/vc_section][vc_section css=\".vc_custom_1649209804184{background-color: #f6faff !important;}\" el_class=\"p-md-0 pt-md-5\"][vc_row el_class=\"container mx-auto align-items-center p-md-0 pt-5\"][vc_column el_class=\"p-0\"][\/vc_column][\/vc_row][\/vc_section][vc_section css=\".vc_custom_1649210787516{background-color: #f6faff !important;}\" el_class=\"p-md-0 pt-md-5 pb-md-5\"][vc_row el_class=\"container mx-auto align-items-center\"][vc_column][\/vc_column][\/vc_row][\/vc_section]\n                                        <\/div>\n                                    <\/div>\n                                <\/div>\n                            <\/div><div class=\"mt-3\"><i class=\"fas fa-solid fa-user-tag fa-fw me-2\"><\/i><small class=\"text-muted\">Co-Investigador\/a<\/small><\/div><span class=\"caption-field-publish\"><\/span><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div>[\/vc_tta_section][vc_tta_section title=&#8221;Libros y Monografias&#8221; tab_id=&#8221;libros&#8221;]<link rel=\"stylesheet\" id=\"font-awesome-css\" href=\"https:\/\/cdnjs.cloudflare.com\/ajax\/libs\/font-awesome\/6.5.1\/css\/all.min.css\" type=\"text\/css\" media=\"all\"><div class=\"row m-0 p-0\"><div class=\"col-12 col-md-9 pt-5 pt-md-0 px-md-0 \"><\/div><\/div>[\/vc_tta_section][vc_tta_section title=&#8221;Cap\u00edtulos de Libros&#8221; tab_id=&#8221;cap-libros&#8221;]<link rel=\"stylesheet\" id=\"font-awesome-css\" href=\"https:\/\/cdnjs.cloudflare.com\/ajax\/libs\/font-awesome\/6.5.1\/css\/all.min.css\" type=\"text\/css\" media=\"all\"><div class=\"row m-0 p-0\"><div class=\"col-12 col-md-9 pt-5 pt-md-0 px-md-0 \"><\/div><\/div>[\/vc_tta_section][vc_tta_section title=&#8221;Contacto&#8221; tab_id=&#8221;contacto&#8221;][\/vc_tta_section][\/vc_tta_tabs][\/vc_column][\/vc_row][\/vc_section]<\/p>\n<\/div>","protected":false},"featured_media":9892,"parent":0,"template":"","meta":{"_acf_changed":false,"footnotes":""},"institute_academics":[7],"profile_academics":[14],"class_list":["post-766","academics","type-academics","status-publish","has-post-thumbnail","hentry","institute_academics-instituto-de-ciencias-de-la-educacion","profile_academics-academico"],"rut_academico":"13057208-1","mail_academico":"pablo.rupin@uoh.cl","n_proyectos":"9","n_publicaciones":"8","n_libros":"1","n_cap_libros":"4","n_otros_libros":"0","acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.6 - 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