
{"id":26,"date":"2022-04-21T07:06:43","date_gmt":"2022-04-21T10:06:43","guid":{"rendered":"https:\/\/www.uoh.cl\/instituto-de-ciencias-agroalimentarias\/?page_id=26"},"modified":"2022-04-25T03:21:26","modified_gmt":"2022-04-25T06:21:26","slug":"proyectos","status":"publish","type":"page","link":"https:\/\/www.uoh.cl\/instituto-de-ciencias-agroalimentarias\/proyectos\/","title":{"rendered":"Proyectos"},"content":{"rendered":"<div class=\"wpb-content-wrapper\"><p>[vc_section el_class=&#8221;container mx-auto align-items-center text-right circle&#8211;pattern&#8221; css=&#8221;.vc_custom_1648956589196{padding-top: 3rem !important;}&#8221;][vc_row][vc_column][vc_wp_custommenu nav_menu=&#8221;3&#8243;]<div class=\"breadcrumb\"><ol itemscope itemtype=\"https:\/\/schema.org\/BreadcrumbList\"><li itemprop=\"itemListElement\" itemscope itemtype=\"https:\/\/schema.org\/ListItem\"><a itemprop=\"item\" href=\"http:\/\/www.uoh.cl\"><span itemprop=\"name\">Inicio<\/span><\/a><meta itemprop=\"position\" content=\"1\" \/><li itemprop=\"itemListElement\" itemscope itemtype=\"https:\/\/schema.org\/ListItem\"><a itemprop=\"item\" href=\"https:\/\/www.uoh.cl\/instituto-de-ciencias-agroalimentarias\"><span itemprop=\"name\">Instituto de Ciencias Agroalimentarias, Animales y Ambientales<\/span><\/a><meta itemprop=\"position\" content=\"2\" \/><li itemprop=\"itemListElement\" itemscope itemtype=\"https:\/\/schema.org\/ListItem\"><span itemprop=\"name\">Proyectos <\/span><meta itemprop=\"position\" content=\"3\" \/><\/ol><\/div><div class=\"uoh_title_component-container\"><h1 class=\"title title--ms d-inline-block title--decorator  big\">Proyectos<\/h1><\/div><div class=\"row filter__row m-0 horizontal\"> <form class=\"filter__form p-0 row m-0\" action=\"https:\/\/www.uoh.cl\/instituto-de-ciencias-agroalimentarias\/wp-admin\/admin-ajax.php\" method=\"post\" id=\"filter\"><div class=\"col-12 col-md-6 filter__container-input p-0\"><div class=\"filter__icon-search\"><svg enable-background=\"new 0 0 32 32\" id=\"Editable-line\" version=\"1.1\" viewBox=\"0 0 32 32\" xml:space=\"preserve\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\"><circle cx=\"14\" cy=\"14\" fill=\"none\" id=\"XMLID_42_\" r=\"9\" stroke=\"#000000\" stroke-linecap=\"round\" stroke-linejoin=\"round\" stroke-miterlimit=\"10\" stroke-width=\"2\"><\/circle><line fill=\"none\" id=\"XMLID_44_\" stroke=\"#000000\" stroke-linecap=\"round\" stroke-linejoin=\"round\" stroke-miterlimit=\"10\" stroke-width=\"2\" x1=\"27\" x2=\"20.366\" y1=\"27\" y2=\"20.366\"><\/line><\/svg><\/div><input type=\"text\" class=\"filter__input\" placeholder=\"Buscar Proyectos\" name=\"filter__form-text\" autocomplete=\"off\"\/><\/div><div class=\"col-12 col-md-6 row m-0 justify-content-end p-0\"><input type=\"hidden\" name=\"action\" value=\"uoh_filter\" \/><input type=\"hidden\" name=\"posttype\" value=\"projects\" \/><div class=\"loading\"><svg version=\"1.1\" id=\"L5\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" x=\"0px\" y=\"0px\" viewBox=\"0 0 100 100\" enable-background=\"new 0 0 0 0\" xml:space=\"preserve\">\n                  <circle fill=\"#42a0f8\" stroke=\"none\" cx=\"6\" cy=\"50\" r=\"6\">\n                    <animateTransform attributeName=\"transform\" dur=\"1s\" type=\"translate\" values=\"0 15 ; 0 -15; 0 15\" repeatCount=\"indefinite\" begin=\"0.1\"><\/animateTransform>\n                  <\/circle>\n                  <circle fill=\"#42a0f8\" stroke=\"none\" cx=\"30\" cy=\"50\" r=\"6\">\n                    <animateTransform attributeName=\"transform\" dur=\"1s\" type=\"translate\" values=\"0 10 ; 0 -10; 0 10\" repeatCount=\"indefinite\" begin=\"0.2\"><\/animateTransform>\n                  <\/circle>\n                  <circle fill=\"#42a0f8\" stroke=\"none\" cx=\"54\" cy=\"50\" r=\"6\">\n                    <animateTransform attributeName=\"transform\" dur=\"1s\" type=\"translate\" values=\"0 5 ; 0 -5; 0 5\" repeatCount=\"indefinite\" begin=\"0.3\"><\/animateTransform>\n                  <\/circle>\n                <\/svg><\/div><button type=\"submit\" class=\"button__arrow\"> <svg version=\"1.1\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" x=\"0px\" y=\"0px\" width=\"22px\"height=\"22px\" viewBox=\"0 0 22 22\" style=\"overflow:visible;enable-background:new 0 0 80 64.6;\" xml:space=\"preserve\"><g clip-path=\"url(#acA)\"><path fill-rule=\"evenodd\" d=\"M21.913 11.266a.93.93 0 000-.711c-.022-.056-.063-.097-.091-.144s-.053-.103-.097-.15L12.306.294c-.357-.379-.955-.394-1.334-.038s-.394.955-.038 1.334l7.917 8.374H.927a.95.95 0 00-.908.983.946.946 0 00.908.908h17.924l-8.089 8.552c-.357.379-.341.977.034 1.334s.977.341 1.334-.034l9.594-10.148c.044-.044.063-.1.097-.15.028-.047.069-.088.091-.141z\"\/><\/g><defs><clipPath id=\"acA\"><path fill=\"#fff\" d=\"M0 0h22v22H0z\"\/><\/clipPath><\/defs><\/svg><\/button><\/div><\/form><\/div>[\/vc_column][\/vc_row][\/vc_section][vc_section css=&#8221;.vc_custom_1650785168913{background-color: #f6faff !important;}&#8221; el_class=&#8221;p-md-0&#8243;][vc_row el_class=&#8221;container mx-auto p-md-0&#8243;][vc_column width=&#8221;1\/4&#8243;]<div class=\"row filter__row margin-box-vertical box-vertical\"> <form  p-0 row m-0\" action=\"https:\/\/www.uoh.cl\/instituto-de-ciencias-agroalimentarias\/wp-admin\/admin-ajax.php\" method=\"post\" id=\"filter__vertical\"><div class=\"select__for-authors\">\n                                <span> Ordenar Resultados<\/span>\n\n                                <div class=\"select__for-authors-input\">\n                                    <select name=\"order\" id=\"order\" class=\"select__author mb-4\">\n                                        <option value=\"desc\">M\u00e1s Nuevos<\/option>\n                                        <option value=\"asc\">M\u00e1s Antiguos<\/option>\n                                    <\/select>\n                                <\/div>\n                            <\/div><div class=\"select__for-authors mb-2\"><span> Filtrar por autor<\/span><input type=\"text\" id=\"autocomplete__authors\" name=\"author\" placeholder=\"Buscar autor\" autocomplete=\"off\"><div class=\"loading loading-author\"><svg version=\"1.1\" id=\"L5\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" x=\"0px\" y=\"0px\" viewBox=\"0 0 100 100\" enable-background=\"new 0 0 0 0\" xml:space=\"preserve\">\n                  <circle fill=\"#42a0f8\" stroke=\"none\" cx=\"6\" cy=\"50\" r=\"6\">\n                    <animateTransform attributeName=\"transform\" dur=\"1s\" type=\"translate\" values=\"0 15 ; 0 -15; 0 15\" repeatCount=\"indefinite\" begin=\"0.1\"><\/animateTransform>\n                  <\/circle>\n                  <circle fill=\"#42a0f8\" stroke=\"none\" cx=\"30\" cy=\"50\" r=\"6\">\n                    <animateTransform attributeName=\"transform\" dur=\"1s\" type=\"translate\" values=\"0 10 ; 0 -10; 0 10\" repeatCount=\"indefinite\" begin=\"0.2\"><\/animateTransform>\n                  <\/circle>\n                  <circle fill=\"#42a0f8\" stroke=\"none\" cx=\"54\" cy=\"50\" r=\"6\">\n                    <animateTransform attributeName=\"transform\" dur=\"1s\" type=\"translate\" values=\"0 5 ; 0 -5; 0 5\" repeatCount=\"indefinite\" begin=\"0.3\"><\/animateTransform>\n                  <\/circle>\n                <\/svg><\/div><div id=\"user__option\">\n                        <li class=\"academic-list pe-4 py-2 inline\"><a target=\"__blank\" href=\"\"><img decoding=\"async\" width=\"150\" height=\"150\" src=\"\" class=\"attachment-thumbnail size-thumbnail wp-post-image\" alt=\"\" ><\/a><h5 class=\"name-user-option\"><em class=\"d-block font-style-normal name-user-option-em\"> <\/em><\/h5><\/li>\n                        <div class=\"btn-close\"><\/div>\n                        <\/div><div id=\"someElem\"><\/div><\/div><div class=\"tax_select mt-4\">\n                    <span class=\"col-12 p-0  d-block\"> Filtrar por Categor\u00eda<\/span><div class=\"select__for-authors-input\"><select name=\"tax\" class=\"select__author mb-4\"><option value=\"-1\" class=\"filter__option-title\">Seleccionar <\/option><\/select><\/div><\/div><div class=\"tags-cloud mt-2 d-block mb-4\">\n                    <span class=\"col-12 p-0 mb-3 d-block\"> Filtrar por tema de int\u00e9res<\/span><\/div><\/div><input type=\"hidden\" name=\"action\" value=\"uoh_filter\" \/><input type=\"hidden\" name=\"posttype\" value=\"projects\" \/>[\/vc_column][vc_column width=&#8221;3\/4&#8243;]<link rel=\"stylesheet\" id=\"font-awesome-css\" href=\"https:\/\/cdnjs.cloudflare.com\/ajax\/libs\/font-awesome\/6.5.1\/css\/all.min.css\" type=\"text\/css\" media=\"all\"><div class=\"row m-0 p-0\"><div class=\"col-12 col-md-9 pt-5 pt-md-0 px-md-0 \"><\/div><\/div><div class=\"content-holder row m-0 p-0 aling-items-center pt-5 pb-5 \"><div class=\"row  large--swipper-content p-0 \"><div class=\"\"><div class=\"  circle--pattern-bottom-large col-sm-12 col-md-12 img-article\"><div class=\"holder-publish col-md-12\" style=\"border-bottom: 1px solid #48A2F9\"><div class=\"content-holder h-100 component-border overflow-hidden row m-0 p-4 aling-items-center\"><ul class=\"p-0 list-style-none\"><li class=\"p-0 ms-1\"><i class=\"fa fa-regular fa-calendar fa-fw ms-1\"><\/i>Septiembre 2024<\/li><\/ul><div class=\"caption col-12 p-0 col-md-12 row m-0 align-items-center\"><div class=\"px-md-1\"><small class=\"badge rounded-pill fw-semibold\" style=\"background-color:#48A2F9 !important; color:#FFF\">En Ejecuci\u00f3n<\/small><small class=\"ms-2 badge rounded-pill fw-semibold\" style=\"background-color:#F0F1F3 !important; color:#797979\"><i class=\"fa fa-solid fa-lg fa-money-check-dollar fa-fw me-1\"><\/i>International Centre for Antimicrobial Resistance Solutions (ICARS)<\/small>\n                            <div class=\"accordion accordion-flush\" id=\"11506\">\n                                <div class=\"accordion-item\">\n                                    <h3 class=\"my-0 small-space pt-2 title-ss text-decoration-none accordion-header\">\n                                        <a role=\"button\" class=\"bg-transparent p-0\" href=\"\">\n                                            <i class=\"fas fa-solid fa-link fa-fw me-2\"><\/i>\n                                            Surveillance, alert, and response system (SVAR) for the use of antimicrobials in Chilean salmon farming\n                                        <\/a><\/h3>\n                                    <div id=\"collapse-11506\" class=\"accordion-collapse collapse\" data-bs-parent=\"#11506\">\n                                        <div class=\"accordion-body p-0 pt-4 pb-4\">\n                                            [vc_section el_class=\"container mx-auto align-items-center circle--pattern\" css=\".vc_custom_1648956589196{padding-top: 3rem !important;}\"][vc_row el_class=\"pb-5\"][vc_column][vc_wp_custommenu nav_menu=\"6\"][uoh_breadcrumb_component automatic_breadcrumb=\"true\"][uoh_title_component title_dropdown=\"big\" title_decorator=\"true\"]{{title}}[\/uoh_title_component][vc_column_text css=\"\"]The use of antimicrobials (AMU) in the salmon farming industry in Chile is concentrated in the sea fattening phase of the production cycle. In 2022, 91% of the AMU in fattening farms was for treatment of Piscirickettsia salmonis (Sernapesca, 2023), the main disease-causing pathogen affecting farmed salmon in Chile (Rozas and Enriquez, 2014).\r\n\r\nTo control P. salmonis, a series of preventive strategies have been adopted. Nevertheless, the incidence of P. salmonis remains high; resulting in high mortality rates (Jakob et al., 2014) and extensive AMU. The use of antimicrobials is exacerbated by current management practices in salmon farms as well as a lack of standardization in treatment guidelines and practices between veterinarians and companies (e.g. treatment of all or selected cages, dosage, etc.), but also because of limited consolidation, communication and use of available AMU data.\r\n\r\nThe aim of this project is to reduce antimicrobial consumption in salmon farming in Los Lagos and Aysen regions where P. salmonis is a challenge and improve science-based governance of AMU in the salmon farming sector through a surveillance, alert and response system (SVARS). The project will be implemented in two phases. Phase one will focus on increasing the knowledge of AMU drivers by developing a catalog of practices and factors that impact the use of antimicrobials and conduct a cost-effectiveness analysis to assess the more cost efficient alternative methods to AMU practices. The catalog will be compiled in a format that can be used to implement improvements on high AMU farms. Different AMU metrics will be reviewed and selected to differentiate farms with low, medium and high AMU. In addition, the legislative requirements to develop and sustain a surveillance, alert and response system (SVARS) to reduce AMU in Chilean salmon farming will be reviewed. Finally, the infrastructural and operational requirements for the platform will be assessed and the design of the platform will be completed, integrating geospatial and health information.\r\n\r\nIn phase two, the SVARS will categorize the farms based on their AMU levels. The high use farms will be recruited to a Randomized Controlled Trial where intervention farms will implement practices and methods from the catalog created in phase one to reduce AMU. The outcomes and the effectiveness of the SVARS will be quantitatively and qualitatively assessed. Finally, results and outcomes of establishing and implementing the SVARS will be shared with relevant stakeholders in Chile, to low-and middle-income countries in the region and beyond, e.g. through workshops and education training programs in order to disseminate the results.[\/vc_column_text][\/vc_column][\/vc_row][\/vc_section][vc_section css=\".vc_custom_1649209804184{background-color: #f6faff !important;}\" el_class=\"p-md-0 pt-md-5\"][vc_row el_class=\"container mx-auto align-items-center p-md-0 pt-5\"][vc_column el_class=\"p-0\"][\/vc_column][\/vc_row][\/vc_section][vc_section css=\".vc_custom_1649210787516{background-color: #f6faff !important;}\" el_class=\"p-md-0 pt-md-5 pb-md-5\"][vc_row el_class=\"container mx-auto align-items-center\"][vc_column][\/vc_column][\/vc_row][\/vc_section]\n                                        <\/div>\n                                    <\/div>\n                                <\/div>\n                            <\/div><div class=\"mt-3\"><i class=\"fas fa-solid fa-user-tag fa-fw me-2\"><\/i><small class=\"text-muted\">Investigador\/a Responsable<\/small><\/div><span class=\"caption-field-publish\"><\/span><\/div><\/div><\/div><\/div><\/div><div class=\"  circle--pattern-bottom-large col-sm-12 col-md-12 img-article\"><div class=\"holder-publish col-md-12\" style=\"border-bottom: 1px solid #48A2F9\"><div class=\"content-holder h-100 component-border overflow-hidden row m-0 p-4 aling-items-center\"><ul class=\"p-0 list-style-none\"><li class=\"p-0 ms-1 me-2\"><i class=\"fa fa-solid fa-id-card-clip fa-fw\"><\/i> 24I10188<\/li><li class=\"p-0 ms-1\"><i class=\"fa fa-regular fa-calendar fa-fw ms-1\"><\/i>Junio 2024 - Junio 2026<\/li><\/ul><div class=\"caption col-12 p-0 col-md-12 row m-0 align-items-center\"><div class=\"px-md-1\"><small class=\"badge rounded-pill fw-semibold\" style=\"background-color:#48A2F9 !important; color:#FFF\">En Ejecuci\u00f3n<\/small><small class=\"ms-2 badge rounded-pill fw-semibold\" style=\"background-color:#F0F1F3 !important; color:#797979\"><i class=\"fa fa-solid fa-lg fa-money-check-dollar fa-fw me-1\"><\/i>Agencia Nacional de Investigaci\u00f3n y Desarrollo - ANID<\/small>\n                            <div class=\"accordion accordion-flush\" id=\"11508\">\n                                <div class=\"accordion-item\">\n                                    <h3 class=\"my-0 small-space pt-2 title-ss text-decoration-none accordion-header\">\n                                        <a role=\"button\" class=\"bg-transparent p-0\" href=\"\">\n                                            <i class=\"fas fa-solid fa-link fa-fw me-2\"><\/i>\n                                            Herramienta molecular para el monitoreo de la sensibilidad farmacol\u00f3gica de productos antiparasitarios contra el piojo de mar en la industria salmonera\n                                        <\/a><\/h3>\n                                    <div id=\"collapse-11508\" class=\"accordion-collapse collapse\" data-bs-parent=\"#11508\">\n                                        <div class=\"accordion-body p-0 pt-4 pb-4\">\n                                            [vc_section el_class=\"container mx-auto align-items-center circle--pattern\" css=\".vc_custom_1648956589196{padding-top: 3rem !important;}\"][vc_row el_class=\"pb-5\"][vc_column][vc_wp_custommenu nav_menu=\"6\"][uoh_breadcrumb_component automatic_breadcrumb=\"true\"][uoh_title_component title_dropdown=\"big\" title_decorator=\"true\"]{{title}}[\/uoh_title_component][vc_column_text css=\"\"]Objetivo General\r\nDesarrollar un kit de qPCR que permita evaluar con precisi\u00f3n la sensibilidad farmacol\u00f3gica de C.\r\nrogercresseyi a tratamientos como inhibidores de quitina mediante asociaci\u00f3n estad\u00edstica entre\r\nfrecuencia de marcadores gen\u00f3micos y eficacia de tratamientos en campo.\r\n\r\nObjetivos Espec\u00edficos\r\n1. Validar estad\u00edsticamente la relaci\u00f3n entre las variantes gen\u00f3micas detectadas por el kit de\r\nqPCR y la resistencia a tratamientos con inhibidores de quitina.\r\n2. Establecer un protocolo de buenas pr\u00e1cticas de laboratorio para la correcta aplicaci\u00f3n del\r\nkit de qPCR.\r\n3. Implementar capacitaciones para laboratorios y culminar con la certificaci\u00f3n de aquellos\r\naptos para aplicar la t\u00e9cnica con eficacia.[\/vc_column_text][\/vc_column][\/vc_row][\/vc_section][vc_section css=\".vc_custom_1649209804184{background-color: #f6faff !important;}\" el_class=\"p-md-0 pt-md-5\"][vc_row el_class=\"container mx-auto align-items-center p-md-0 pt-5\"][vc_column el_class=\"p-0\"][\/vc_column][\/vc_row][\/vc_section][vc_section css=\".vc_custom_1649210787516{background-color: #f6faff !important;}\" el_class=\"p-md-0 pt-md-5 pb-md-5\"][vc_row el_class=\"container mx-auto align-items-center\"][vc_column][\/vc_column][\/vc_row][\/vc_section]\n                                        <\/div>\n                                    <\/div>\n                                <\/div>\n                            <\/div><div class=\"mt-3\"><i class=\"fas fa-solid fa-user-tag fa-fw me-2\"><\/i><small class=\"text-muted\">Co-Investigador\/a<\/small><\/div><span class=\"caption-field-publish\"><\/span><\/div><\/div><\/div><\/div><\/div><div class=\"  circle--pattern-bottom-large col-sm-12 col-md-12 img-article\"><div class=\"holder-publish col-md-12\" style=\"border-bottom: 1px solid #35DB54\"><div class=\"content-holder h-100 component-border overflow-hidden row m-0 p-4 aling-items-center\"><ul class=\"p-0 list-style-none\"><li class=\"p-0 ms-1 me-2\"><i class=\"fa fa-solid fa-id-card-clip fa-fw\"><\/i> FOVI230047<\/li><li class=\"p-0 ms-1\"><i class=\"fa fa-regular fa-calendar fa-fw ms-1\"><\/i>Enero 2024 - Diciembre 2024<\/li><\/ul><div class=\"caption col-12 p-0 col-md-12 row m-0 align-items-center\"><div class=\"px-md-1\"><small class=\"badge rounded-pill fw-semibold\" style=\"background-color:#35DB54 !important; color:#FFF\">Finalizado<\/small><small class=\"ms-2 badge rounded-pill fw-semibold\" style=\"background-color:#F0F1F3 !important; color:#797979\"><i class=\"fa fa-solid fa-lg fa-money-check-dollar fa-fw me-1\"><\/i>Agencia Nacional de Investigaci\u00f3n y Desarrollo - ANID<\/small>\n                            <div class=\"accordion accordion-flush\" id=\"11502\">\n                                <div class=\"accordion-item\">\n                                    <h3 class=\"my-0 small-space pt-2 title-ss text-decoration-none accordion-header\">\n                                        <a role=\"button\" class=\"bg-transparent p-0\" href=\"\">\n                                            <i class=\"fas fa-solid fa-link fa-fw me-2\"><\/i>\n                                            Vinculaci\u00f3n internacional para la evaluaci\u00f3n de la capacidad centinela de moluscos bivalvos filtradores en el monitoreo de contaminantes emergentes en \u00e1reas costeras marinas\n                                        <\/a><\/h3>\n                                    <div id=\"collapse-11502\" class=\"accordion-collapse collapse\" data-bs-parent=\"#11502\">\n                                        <div class=\"accordion-body p-0 pt-4 pb-4\">\n                                            [vc_section el_class=\"container mx-auto align-items-center circle--pattern\" css=\".vc_custom_1648956589196{padding-top: 3rem !important;}\"][vc_row el_class=\"pb-5\"][vc_column][vc_wp_custommenu nav_menu=\"6\"][uoh_breadcrumb_component automatic_breadcrumb=\"true\"][uoh_title_component title_dropdown=\"big\" title_decorator=\"true\"]{{title}}[\/uoh_title_component][vc_column_text css=\"\"]Vinculaci\u00f3n internacional para la evaluaci\u00f3n de la capacidad centinela de moluscos bivalvos filtradores en el monitoreo de contaminantes emergentes en \u00e1reas costeras marinas[\/vc_column_text][\/vc_column][\/vc_row][\/vc_section][vc_section css=\".vc_custom_1649209804184{background-color: #f6faff !important;}\" el_class=\"p-md-0 pt-md-5\"][vc_row el_class=\"container mx-auto align-items-center p-md-0 pt-5\"][vc_column el_class=\"p-0\"][\/vc_column][\/vc_row][\/vc_section][vc_section css=\".vc_custom_1649210787516{background-color: #f6faff !important;}\" el_class=\"p-md-0 pt-md-5 pb-md-5\"][vc_row el_class=\"container mx-auto align-items-center\"][vc_column][\/vc_column][\/vc_row][\/vc_section]\n                                        <\/div>\n                                    <\/div>\n                                <\/div>\n                            <\/div><div class=\"mt-3\"><i class=\"fas fa-solid fa-user-tag fa-fw me-2\"><\/i><small class=\"text-muted\">Co-Investigador\/a<\/small><\/div><span class=\"caption-field-publish\"><\/span><\/div><\/div><\/div><\/div><\/div><div class=\"  circle--pattern-bottom-large col-sm-12 col-md-12 img-article\"><div class=\"holder-publish col-md-12\" style=\"border-bottom: 1px solid #48A2F9\"><div class=\"content-holder h-100 component-border overflow-hidden row m-0 p-4 aling-items-center\"><ul class=\"p-0 list-style-none\"><li class=\"p-0 ms-1\"><i class=\"fa fa-regular fa-calendar fa-fw ms-1\"><\/i>Marzo 2022 - Febrero 2024<\/li><\/ul><div class=\"caption col-12 p-0 col-md-12 row m-0 align-items-center\"><div class=\"px-md-1\"><small class=\"badge rounded-pill fw-semibold\" style=\"background-color:#48A2F9 !important; color:#FFF\">En Ejecuci\u00f3n<\/small><small class=\"ms-2 badge rounded-pill fw-semibold\" style=\"background-color:#F0F1F3 !important; color:#797979\"><i class=\"fa fa-solid fa-lg fa-money-check-dollar fa-fw me-1\"><\/i>Agencia Nacional de Investigaci\u00f3n y Desarrollo - ANID<\/small>\n                            <div class=\"accordion accordion-flush\" id=\"11476\">\n                                <div class=\"accordion-item\">\n                                    <h3 class=\"my-0 small-space pt-2 title-ss text-decoration-none accordion-header\">\n                                        <a role=\"button\" class=\"bg-transparent p-0\" href=\"\">\n                                            <i class=\"fas fa-solid fa-link fa-fw me-2\"><\/i>\n                                            The epidemiology of antimicrobial resistance in a region with intense aquaculture activity: evaluating the role of bivalve mollusks as sentinel organisms and potential impacts on public health\n                                        <\/a><\/h3>\n                                    <div id=\"collapse-11476\" class=\"accordion-collapse collapse\" data-bs-parent=\"#11476\">\n                                        <div class=\"accordion-body p-0 pt-4 pb-4\">\n                                            [vc_section el_class=\"container mx-auto align-items-center circle--pattern\" css=\".vc_custom_1648956589196{padding-top: 3rem !important;}\"][vc_row el_class=\"pb-5\"][vc_column][vc_wp_custommenu nav_menu=\"6\"][uoh_breadcrumb_component automatic_breadcrumb=\"true\"][uoh_title_component title_dropdown=\"big\" title_decorator=\"true\"]{{title}}[\/uoh_title_component][vc_column_text css=\"\"]Antimicrobial resistance (AMR) is a phenomenon that happens when bacteria become tolerant to antibiotics used to treat the infections they cause. Antibiotics are key therapeutic tools to treat many human and animal infectious diseases; consequently, keeping their activity on bacteria is fundamental for public and animal health. Aquaculture farming is known for using large amounts of antibiotics, making this activity particularly relevant in development and spread of AMR in aquatic environments. There is evidence in Chile that aquaculture activity increases the presence of resistant bacteria and their corresponding genes in marine sediments directly impacted by salmon farms; however, these evaluations are limited to few locations which hampers a generalization of these conclusions to other salmon farming sites in Chilean waters. There is also evidence suggesting that aquaculture-associated resistance genes present in marine sediments might be transferred to bacteria with pathogenic potential in humans such as Escherichia coli, but no studies have reported the presence of resistance traits in such bacteria in the marine environment from areas impacted by salmon farming in Chile. In countries like Norway, bivalve mollusks are used to monitor antibiotic resistance in Enterobacteria in the marine environment; therefore, they could also be useful for monitoring AMR associated with salmon farming and other anthropogenic sources in Chile. Sampling of bivalve mollusks represents an important logistical advantage to complex and expensive seabed sediment sampling. Los Lagos is the region with the highest historical production of farmed salmon in Chile; then, it is a suitable area to investigate the impact of aquaculture-sourced AMR in the marine environment.\r\nThe general objective of this proposal is to investigate aquaculture-associated AMR in the marine environment of Los Lagos region from an epidemiologic approach, using bivalve mollusks as sentinel organisms and E. coli as the indicator bacterium. Specific objectives include: 1) to detect, characterize and estimate the prevalence of AMR in E. coli isolated from bivalve mollusks in the Los Lagos region, through a region-level sampling; 2) to study the spatial variability of AMR in E. coli isolated from bivalve mollusks from Los Lagos region; 3) to evaluate the effect of salmon farming activity on the richness and intensity of AMR in E. coli isolated from bivalves from Los Lagos region, controlling for potential confounding factors; and 4) to determine whether significant differences exist in the accumulation of E. coli and resistant E. coli in bivalve mollusks between the sampled bivalve species, accounting for environmental and biological factors.\r\nBivalve mollusks samples will be obtained the 130 sampling stations set along the coast of Los Lagos by the National Program for Surveillance and Control of Harmful Algal Blooms Intoxications (red tides) coordinated by the Ministry of Health. Thirty-three additional sampling stations will be set in the same study area in order to achieve the calculated total sample size of 163 sampling stations. At each sampling station bivalve mollusks will be sampled to quantify E. coli and to detect and characterize both phenotypic and genotypic AMR in this bacterium. The study will be focused in 29 antimicrobial resistance genes (ARGs) and 20 antibiotics commonly used in salmon farming or for which resistance has been detected in previous studies. The antimicrobial susceptibility will be performed by estimating the minimal inhibitory concentrations (MICs) for each antibiotic using the VITEK2 technology. The genotypic analysis will be carried out by means of the detection target ARGs, through PCR. Spatial clustering will be examined for each antibiotic tested using MIC values and the ARG richness index; global clustering will be evaluated through the Moran\u0092s I statistic, while local clustering will be examined by means of the spatial scan statistic. ARG richness will be modeled as a function of the local salmon farming intensity expressed as the number of active salmon farms within 10 km seaway distance from the bivalve sampling location, using a Poisson mixed-effects model in order to control for other AMR sources and important environmental variables. Similar models will be constructed using MICs as the outcome for antimicrobials that show substantial variability in this parameter. Finally, the abundance of both total and resistant E. coli (MPN\/100g) found in bivalve mollusks will be modeled as a function of the bivalve species sampled, accounting for bivalve size, water temperature, local salmon farming intensity and distance to other AMR sources, using a mixed-effect linear regression model.\r\nThis study will contribute to characterize and to identify the main drivers of the environmental AMR in an area with intense salmon farming activity, and it will help to understand how this AMR can impact public health through potential pathogenic bacteria. In practice, this proposal will be the first extensive epidemiological study in this matter in Chile. Moreover, this proposal will help to determine which bivalve mollusks species are suitable to monitor AMR in environments impacted by salmon farming. All this information will be crucial to set the foundations for a future AMR monitoring program in areas of intense aquaculture.[\/vc_column_text][\/vc_column][\/vc_row][\/vc_section][vc_section css=\".vc_custom_1649209804184{background-color: #f6faff !important;}\" el_class=\"p-md-0 pt-md-5\"][vc_row el_class=\"container mx-auto align-items-center p-md-0 pt-5\"][vc_column el_class=\"p-0\"][\/vc_column][\/vc_row][\/vc_section][vc_section css=\".vc_custom_1649210787516{background-color: #f6faff !important;}\" el_class=\"p-md-0 pt-md-5 pb-md-5\"][vc_row el_class=\"container mx-auto align-items-center\"][vc_column][\/vc_column][\/vc_row][\/vc_section]\n                                        <\/div>\n                                    <\/div>\n                                <\/div>\n                            <\/div><div class=\"mt-3\"><i class=\"fas fa-solid fa-user-tag fa-fw me-2\"><\/i><small class=\"text-muted\">Investigador\/a Responsable<\/small><\/div><span class=\"caption-field-publish\"><\/span><\/div><\/div><\/div><\/div><\/div><div class=\"  circle--pattern-bottom-large col-sm-12 col-md-12 img-article\"><div class=\"holder-publish col-md-12\" style=\"border-bottom: 1px solid #35DB54\"><div class=\"content-holder h-100 component-border overflow-hidden row m-0 p-4 aling-items-center\"><ul class=\"p-0 list-style-none\"><li class=\"p-0 ms-1\"><i class=\"fa fa-regular fa-calendar fa-fw ms-1\"><\/i>Enero 2022 - Diciembre 2024<\/li><\/ul><div class=\"caption col-12 p-0 col-md-12 row m-0 align-items-center\"><div class=\"px-md-1\"><small class=\"badge rounded-pill fw-semibold\" style=\"background-color:#35DB54 !important; color:#FFF\">Finalizado<\/small><small class=\"ms-2 badge rounded-pill fw-semibold\" style=\"background-color:#F0F1F3 !important; color:#797979\"><i class=\"fa fa-solid fa-lg fa-money-check-dollar fa-fw me-1\"><\/i>Ministerio de Educaci\u00f3n<\/small>\n                            <div class=\"accordion accordion-flush\" id=\"11504\">\n                                <div class=\"accordion-item\">\n                                    <h3 class=\"my-0 small-space pt-2 title-ss text-decoration-none accordion-header\">\n                                        <a role=\"button\" class=\"bg-transparent p-0\" href=\"\">\n                                            <i class=\"fas fa-solid fa-link fa-fw me-2\"><\/i>\n                                            Sistema Articulado de Investigaci\u00f3n en Cambio Clim\u00e1tico y Sustentabilidad de Zonas Costeras de Chile (URO RED21992)\n                                        <\/a><\/h3>\n                                    <div id=\"collapse-11504\" class=\"accordion-collapse collapse\" data-bs-parent=\"#11504\">\n                                        <div class=\"accordion-body p-0 pt-4 pb-4\">\n                                            [vc_section el_class=\"container mx-auto align-items-center circle--pattern\" css=\".vc_custom_1648956589196{padding-top: 3rem !important;}\"][vc_row el_class=\"pb-5\"][vc_column][vc_wp_custommenu nav_menu=\"6\"][uoh_breadcrumb_component automatic_breadcrumb=\"true\"][uoh_title_component title_dropdown=\"big\" title_decorator=\"true\"]{{title}}[\/uoh_title_component][vc_column_text css=\"\"]Sistema Articulado de Investigaci\u00f3n en Cambio Clim\u00e1tico y Sustentabilidad de Zonas Costeras de Chile CUECH\/RISUE RED21992[\/vc_column_text][\/vc_column][\/vc_row][\/vc_section][vc_section css=\".vc_custom_1649209804184{background-color: #f6faff !important;}\" el_class=\"p-md-0 pt-md-5\"][vc_row el_class=\"container mx-auto align-items-center p-md-0 pt-5\"][vc_column el_class=\"p-0\"][\/vc_column][\/vc_row][\/vc_section][vc_section css=\".vc_custom_1649210787516{background-color: #f6faff !important;}\" el_class=\"p-md-0 pt-md-5 pb-md-5\"][vc_row el_class=\"container mx-auto align-items-center\"][vc_column][\/vc_column][\/vc_row][\/vc_section]\n                                        <\/div>\n                                    <\/div>\n                                <\/div>\n                            <\/div><div class=\"mt-3\"><i class=\"fas fa-solid fa-user-tag fa-fw me-2\"><\/i><small class=\"text-muted\">Co-Investigador\/a<\/small><\/div><span class=\"caption-field-publish\"><\/span><\/div><\/div><\/div><\/div><\/div><div class=\"  circle--pattern-bottom-large col-sm-12 col-md-12 img-article\"><div class=\"holder-publish col-md-12\" style=\"border-bottom: 1px solid #48A2F9\"><div class=\"content-holder h-100 component-border overflow-hidden row m-0 p-4 aling-items-center\"><ul class=\"p-0 list-style-none\"><li class=\"p-0 ms-1\"><i class=\"fa fa-regular fa-calendar fa-fw ms-1\"><\/i>Abril 2021 - Febrero 2024<\/li><\/ul><div class=\"caption col-12 p-0 col-md-12 row m-0 align-items-center\"><div class=\"px-md-1\"><small class=\"badge rounded-pill fw-semibold\" style=\"background-color:#48A2F9 !important; color:#FFF\">En Ejecuci\u00f3n<\/small>\n                            <div class=\"accordion accordion-flush\" id=\"11478\">\n                                <div class=\"accordion-item\">\n                                    <h3 class=\"my-0 small-space pt-2 title-ss text-decoration-none accordion-header\">\n                                        <a role=\"button\" class=\"bg-transparent p-0\" href=\"\">\n                                            <i class=\"fas fa-solid fa-link fa-fw me-2\"><\/i>\n                                            Characterization of the resistance of indicator bacteria against critical antimicrobials and identification of associated risk factors in healthy dogs from the Metropolitan Region\n                                        <\/a><\/h3>\n                                    <div id=\"collapse-11478\" class=\"accordion-collapse collapse\" data-bs-parent=\"#11478\">\n                                        <div class=\"accordion-body p-0 pt-4 pb-4\">\n                                            [vc_section el_class=\"container mx-auto align-items-center circle--pattern\" css=\".vc_custom_1648956589196{padding-top: 3rem !important;}\"][vc_row el_class=\"pb-5\"][vc_column][vc_wp_custommenu nav_menu=\"6\"][uoh_breadcrumb_component automatic_breadcrumb=\"true\"][uoh_title_component title_dropdown=\"big\" title_decorator=\"true\"]{{title}}[\/uoh_title_component][vc_column_text css=\"\"][\/vc_column_text][\/vc_column][\/vc_row][\/vc_section][vc_section css=\".vc_custom_1649209804184{background-color: #f6faff !important;}\" el_class=\"p-md-0 pt-md-5\"][vc_row el_class=\"container mx-auto align-items-center p-md-0 pt-5\"][vc_column el_class=\"p-0\"][\/vc_column][\/vc_row][\/vc_section][vc_section css=\".vc_custom_1649210787516{background-color: #f6faff !important;}\" el_class=\"p-md-0 pt-md-5 pb-md-5\"][vc_row el_class=\"container mx-auto align-items-center\"][vc_column][\/vc_column][\/vc_row][\/vc_section]\n                                        <\/div>\n                                    <\/div>\n                                <\/div>\n                            <\/div><div class=\"mt-3\"><i class=\"fas fa-solid fa-user-tag fa-fw me-2\"><\/i><small class=\"text-muted\">Co-Investigador\/a<\/small><\/div><span class=\"caption-field-publish\"><\/span><\/div><\/div><\/div><\/div><\/div><div class=\"  circle--pattern-bottom-large col-sm-12 col-md-12 img-article\"><div class=\"holder-publish col-md-12\" style=\"border-bottom: 1px solid #48A2F9\"><div class=\"content-holder h-100 component-border overflow-hidden row m-0 p-4 aling-items-center\"><ul class=\"p-0 list-style-none\"><li class=\"p-0 ms-1\"><i class=\"fa fa-regular fa-calendar fa-fw ms-1\"><\/i>Abril 2021 - Marzo 2023<\/li><\/ul><div class=\"caption col-12 p-0 col-md-12 row m-0 align-items-center\"><div class=\"px-md-1\"><small class=\"badge rounded-pill fw-semibold\" style=\"background-color:#48A2F9 !important; color:#FFF\">En Ejecuci\u00f3n<\/small>\n                            <div class=\"accordion accordion-flush\" id=\"11527\">\n                                <div class=\"accordion-item\">\n                                    <h3 class=\"my-0 small-space pt-2 title-ss text-decoration-none accordion-header\">\n                                        <a role=\"button\" class=\"bg-transparent p-0\" href=\"\">\n                                            <i class=\"fas fa-solid fa-link fa-fw me-2\"><\/i>\n                                            Transferencia Drosophila suzukii: Plaga presente &#8211; Futura convivencia\n                                        <\/a><\/h3>\n                                    <div id=\"collapse-11527\" class=\"accordion-collapse collapse\" data-bs-parent=\"#11527\">\n                                        <div class=\"accordion-body p-0 pt-4 pb-4\">\n                                            [vc_section el_class=\"container mx-auto align-items-center circle--pattern\" css=\".vc_custom_1648956589196{padding-top: 3rem !important;}\"][vc_row el_class=\"pb-5\"][vc_column][vc_wp_custommenu nav_menu=\"6\"][uoh_breadcrumb_component automatic_breadcrumb=\"true\"][uoh_title_component title_dropdown=\"big\" title_decorator=\"true\"]{{title}}[\/uoh_title_component][vc_column_text css=\"\"][\/vc_column_text][\/vc_column][\/vc_row][\/vc_section][vc_section css=\".vc_custom_1649209804184{background-color: #f6faff !important;}\" el_class=\"p-md-0 pt-md-5\"][vc_row el_class=\"container mx-auto align-items-center p-md-0 pt-5\"][vc_column el_class=\"p-0\"][\/vc_column][\/vc_row][\/vc_section][vc_section css=\".vc_custom_1649210787516{background-color: #f6faff !important;}\" el_class=\"p-md-0 pt-md-5 pb-md-5\"][vc_row el_class=\"container mx-auto align-items-center\"][vc_column][\/vc_column][\/vc_row][\/vc_section]\n                                        <\/div>\n                                    <\/div>\n                                <\/div>\n                            <\/div><div class=\"mt-3\"><i class=\"fas fa-solid fa-user-tag fa-fw me-2\"><\/i><small class=\"text-muted\">Investigador\/a Responsable<\/small><\/div><span class=\"caption-field-publish\"><\/span><\/div><\/div><\/div><\/div><\/div><div class=\"  circle--pattern-bottom-large col-sm-12 col-md-12 img-article\"><div class=\"holder-publish col-md-12\" style=\"border-bottom: 1px solid #35DB54\"><div class=\"content-holder h-100 component-border overflow-hidden row m-0 p-4 aling-items-center\"><ul class=\"p-0 list-style-none\"><li class=\"p-0 ms-1\"><i class=\"fa fa-regular fa-calendar fa-fw ms-1\"><\/i>Diciembre 2020 - Marzo 2022<\/li><\/ul><div class=\"caption col-12 p-0 col-md-12 row m-0 align-items-center\"><div class=\"px-md-1\"><small class=\"badge rounded-pill fw-semibold\" style=\"background-color:#35DB54 !important; color:#FFF\">Finalizado<\/small><small class=\"ms-2 badge rounded-pill fw-semibold\" style=\"background-color:#F0F1F3 !important; color:#797979\"><i class=\"fa fa-solid fa-lg fa-money-check-dollar fa-fw me-1\"><\/i>Agencia Nacional de Investigaci\u00f3n y Desarrollo - ANID<\/small>\n                            <div class=\"accordion accordion-flush\" id=\"11480\">\n                                <div class=\"accordion-item\">\n                                    <h3 class=\"my-0 small-space pt-2 title-ss text-decoration-none accordion-header\">\n                                        <a role=\"button\" class=\"bg-transparent p-0\" href=\"\">\n                                            <i class=\"fas fa-solid fa-link fa-fw me-2\"><\/i>\n                                            Generaci\u00f3n de capital social entre los productores ap\u00edcolas y la universidad de O\u0092Higgins, para mejorar el estatus sanitario y epidemiol\u00f3gico de las colmenas de la regi\u00f3n de O\u0092Higgins\n                                        <\/a><\/h3>\n                                    <div id=\"collapse-11480\" class=\"accordion-collapse collapse\" data-bs-parent=\"#11480\">\n                                        <div class=\"accordion-body p-0 pt-4 pb-4\">\n                                            [vc_section el_class=\"container mx-auto align-items-center circle--pattern\" css=\".vc_custom_1648956589196{padding-top: 3rem !important;}\"][vc_row el_class=\"pb-5\"][vc_column][vc_wp_custommenu nav_menu=\"6\"][uoh_breadcrumb_component automatic_breadcrumb=\"true\"][uoh_title_component title_dropdown=\"big\" title_decorator=\"true\"]{{title}}[\/uoh_title_component][vc_column_text css=\"\"]El objetivo es dise\u00f1ar e implementar una estrategia transdisciplinaria de vinculaci\u00f3n entre los apicultores de la regi\u00f3n y la Universidad de O'Higgins, que permita construir una \u0093Hoja de Ruta\u0094 para resolver las brechas existentes en el sector y definir las l\u00edneas de investigaci\u00f3n aplicada a desarrollarse. Esto permitir\u00e1 mejorar la asociatividad de los apicultores, mejorar la salud de las colmenas, los servicios de polinizaci\u00f3n y por ende la productividad ap\u00edcola regional.[\/vc_column_text][\/vc_column][\/vc_row][\/vc_section][vc_section css=\".vc_custom_1649209804184{background-color: #f6faff !important;}\" el_class=\"p-md-0 pt-md-5\"][vc_row el_class=\"container mx-auto align-items-center p-md-0 pt-5\"][vc_column el_class=\"p-0\"][\/vc_column][\/vc_row][\/vc_section][vc_section css=\".vc_custom_1649210787516{background-color: #f6faff !important;}\" el_class=\"p-md-0 pt-md-5 pb-md-5\"][vc_row el_class=\"container mx-auto align-items-center\"][vc_column][\/vc_column][\/vc_row][\/vc_section]\n                                        <\/div>\n                                    <\/div>\n                                <\/div>\n                            <\/div><div class=\"mt-3\"><i class=\"fas fa-solid fa-user-tag fa-fw me-2\"><\/i><small class=\"text-muted\">Co-Investigador\/a<\/small><\/div><span class=\"caption-field-publish\"><\/span><\/div><\/div><\/div><\/div><\/div><div class=\"  circle--pattern-bottom-large col-sm-12 col-md-12 img-article\"><div class=\"holder-publish col-md-12\" style=\"border-bottom: 1px solid #35DB54\"><div class=\"content-holder h-100 component-border overflow-hidden row m-0 p-4 aling-items-center\"><ul class=\"p-0 list-style-none\"><li class=\"p-0 ms-1\"><i class=\"fa fa-regular fa-calendar fa-fw ms-1\"><\/i>Julio 2020 - Marzo 2021<\/li><\/ul><div class=\"caption col-12 p-0 col-md-12 row m-0 align-items-center\"><div class=\"px-md-1\"><small class=\"badge rounded-pill fw-semibold\" style=\"background-color:#35DB54 !important; color:#FFF\">Finalizado<\/small><small class=\"ms-2 badge rounded-pill fw-semibold\" style=\"background-color:#F0F1F3 !important; color:#797979\"><i class=\"fa fa-solid fa-lg fa-money-check-dollar fa-fw me-1\"><\/i>Agencia Nacional de Investigaci\u00f3n y Desarrollo - ANID<\/small>\n                            <div class=\"accordion accordion-flush\" id=\"11482\">\n                                <div class=\"accordion-item\">\n                                    <h3 class=\"my-0 small-space pt-2 title-ss text-decoration-none accordion-header\">\n                                        <a role=\"button\" class=\"bg-transparent p-0\" href=\"\">\n                                            <i class=\"fas fa-solid fa-link fa-fw me-2\"><\/i>\n                                            Estudio epidemiol\u00f3gico observacional para evaluar el efecto de medidas de control gubernamentales sobre la din\u00e1mica espacio-temporal de Covid-19 en Chile\n                                        <\/a><\/h3>\n                                    <div id=\"collapse-11482\" class=\"accordion-collapse collapse\" data-bs-parent=\"#11482\">\n                                        <div class=\"accordion-body p-0 pt-4 pb-4\">\n                                            [vc_section el_class=\"container mx-auto align-items-center circle--pattern\" css=\".vc_custom_1648956589196{padding-top: 3rem !important;}\"][vc_row el_class=\"pb-5\"][vc_column][vc_wp_custommenu nav_menu=\"6\"][uoh_breadcrumb_component automatic_breadcrumb=\"true\"][uoh_title_component title_dropdown=\"big\" title_decorator=\"true\"]{{title}}[\/uoh_title_component][vc_column_text css=\"\"]A\u00fan lejos de tener una vacuna efectiva y segura, los gobiernos nacionales han tenido que establecer medidas sanitarias (e.g. cuarentena) para reducir el impacto de la pandemia de COVID-19. Sin embargo, no existe claridad respecto a cu\u00e1les medidas son las m\u00e1s eficaces y c\u00f3mo la efectividad de \u00e9stas es afectada por diferentes contextos sociales, demogr\u00e1ficos y epidemiol\u00f3gicos. El objetivo de esta propuesta es desarrollar un estudio observacional para evaluar el impacto de las diferentes medidas de control aplicadas por la autoridad sanitaria sobre la din\u00e1mica de COVID-19, a nivel comunal y de \u00e1reas metropolitanas, utilizando la informaci\u00f3n generada por el Ministerio de Salud. Los datos ser\u00e1n analizados utilizando modelos de regresi\u00f3n para datos de conteo, lo que permitir\u00e1 evaluar potenciales desfases en el tiempo de los efectos de las medidas de control, junto con considerar el efecto de variables potencialmente confundentes. Al finalizar este estudio, la autoridad sanitaria dispondr\u00e1 de evidencia cient\u00edfica para sustentar el establecimiento de diferentes medidas de control para COVID-19, dependiendo de contextos sociales, demogr\u00e1ficos y epidemiol\u00f3gicos, permitiendo enfatizar aquellas medidas m\u00e1s adecuadas para cada caso. Los modelos quedar\u00e1n disponibles en una aplicaci\u00f3n web donde podr\u00e1n ser interrogados por las autoridades sanitarias.[\/vc_column_text][\/vc_column][\/vc_row][\/vc_section][vc_section css=\".vc_custom_1649209804184{background-color: #f6faff !important;}\" el_class=\"p-md-0 pt-md-5\"][vc_row el_class=\"container mx-auto align-items-center p-md-0 pt-5\"][vc_column el_class=\"p-0\"][\/vc_column][\/vc_row][\/vc_section][vc_section css=\".vc_custom_1649210787516{background-color: #f6faff !important;}\" el_class=\"p-md-0 pt-md-5 pb-md-5\"][vc_row el_class=\"container mx-auto align-items-center\"][vc_column][\/vc_column][\/vc_row][\/vc_section]\n                                        <\/div>\n                                    <\/div>\n                                <\/div>\n                            <\/div><div class=\"mt-3\"><i class=\"fas fa-solid fa-user-tag fa-fw me-2\"><\/i><small class=\"text-muted\">Investigador\/a Responsable<\/small><\/div><span class=\"caption-field-publish\"><\/span><\/div><\/div><\/div><\/div><\/div><div class=\"  circle--pattern-bottom-large col-sm-12 col-md-12 img-article\"><div class=\"holder-publish col-md-12\" style=\"border-bottom: 1px solid #35DB54\"><div class=\"content-holder h-100 component-border overflow-hidden row m-0 p-4 aling-items-center\"><ul class=\"p-0 list-style-none\"><li class=\"p-0 ms-1\"><i class=\"fa fa-regular fa-calendar fa-fw ms-1\"><\/i>Abril 2020 - Marzo 2023<\/li><\/ul><div class=\"caption col-12 p-0 col-md-12 row m-0 align-items-center\"><div class=\"px-md-1\"><small class=\"badge rounded-pill fw-semibold\" style=\"background-color:#35DB54 !important; color:#FFF\">Finalizado<\/small><small class=\"ms-2 badge rounded-pill fw-semibold\" style=\"background-color:#F0F1F3 !important; color:#797979\"><i class=\"fa fa-solid fa-lg fa-money-check-dollar fa-fw me-1\"><\/i>Gobierno Regional - GORE<\/small>\n                            <div class=\"accordion accordion-flush\" id=\"11484\">\n                                <div class=\"accordion-item\">\n                                    <h3 class=\"my-0 small-space pt-2 title-ss text-decoration-none accordion-header\">\n                                        <a role=\"button\" class=\"bg-transparent p-0\" href=\"\">\n                                            <i class=\"fas fa-solid fa-link fa-fw me-2\"><\/i>\n                                            Transferencia de  un Modelo de Inocuidad agroalimentaria regional\n                                        <\/a><\/h3>\n                                    <div id=\"collapse-11484\" class=\"accordion-collapse collapse\" data-bs-parent=\"#11484\">\n                                        <div class=\"accordion-body p-0 pt-4 pb-4\">\n                                            [vc_section el_class=\"container mx-auto align-items-center circle--pattern\" css=\".vc_custom_1648956589196{padding-top: 3rem !important;}\"][vc_row el_class=\"pb-5\"][vc_column][vc_wp_custommenu nav_menu=\"6\"][uoh_breadcrumb_component automatic_breadcrumb=\"true\"][uoh_title_component title_dropdown=\"big\" title_decorator=\"true\"]{{title}}[\/uoh_title_component][vc_column_text css=\"\"]Este proyecto tiene como objetivo, ejecutar un sistema de extensi\u00f3n para productores hort\u00edcolas y ap\u00edcolas de la regi\u00f3n de O\u0092Higgins, junto con un sistema de monitoreo de peligros alimentarios, un sistema de cultura de inocuidad y un SELLO o marca de certificaci\u00f3n en base a criterios de inocuidad alimentaria.[\/vc_column_text][\/vc_column][\/vc_row][\/vc_section][vc_section css=\".vc_custom_1649209804184{background-color: #f6faff !important;}\" el_class=\"p-md-0 pt-md-5\"][vc_row el_class=\"container mx-auto align-items-center p-md-0 pt-5\"][vc_column el_class=\"p-0\"][\/vc_column][\/vc_row][\/vc_section][vc_section css=\".vc_custom_1649210787516{background-color: #f6faff !important;}\" el_class=\"p-md-0 pt-md-5 pb-md-5\"][vc_row el_class=\"container mx-auto align-items-center\"][vc_column][\/vc_column][\/vc_row][\/vc_section]\n                                        <\/div>\n                                    <\/div>\n                                <\/div>\n                            <\/div><div class=\"mt-3\"><i class=\"fas fa-solid fa-user-tag fa-fw me-2\"><\/i><small class=\"text-muted\">Co-Investigador\/a<\/small><\/div><span class=\"caption-field-publish\"><\/span><\/div><\/div><\/div><\/div><\/div><div class=\"pagination justify-content-center my-5\"><span aria-current=\"page\" class=\"page-numbers current\">1<\/span>\n<a class=\"page-numbers\" href=\"https:\/\/www.uoh.cl\/instituto-de-ciencias-agroalimentarias\/wp-json\/wp\/v2\/pages\/26\/\/page\/2\">2<\/a>\n<a class=\"page-numbers\" href=\"https:\/\/www.uoh.cl\/instituto-de-ciencias-agroalimentarias\/wp-json\/wp\/v2\/pages\/26\/\/page\/3\">3<\/a>\n<a class=\"next page-numbers\" href=\"https:\/\/www.uoh.cl\/instituto-de-ciencias-agroalimentarias\/wp-json\/wp\/v2\/pages\/26\/\/page\/2\"><div class=\"icon-pagination-next\"> <?xml version=\"1.0\" ?><svg viewBox=\"0 0 96 96\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><title\/><path d=\"M39.3756,48.0022l30.47-25.39a6.0035,6.0035,0,0,0-7.6878-9.223L26.1563,43.3906a6.0092,6.0092,0,0,0,0,9.2231L62.1578,82.615a6.0035,6.0035,0,0,0,7.6878-9.2231Z\"\/><\/svg> <\/div><\/a><\/div><\/div><\/div><\/div>[\/vc_column][\/vc_row][\/vc_section][vc_section css=&#8221;.vc_custom_1649210787516{background-color: #f6faff !important;}&#8221; el_class=&#8221;p-md-0 pt-md-5 pb-md-5&#8243;][vc_row el_class=&#8221;container mx-auto align-items-center text-right&#8221;][vc_column][\/vc_column][\/vc_row][\/vc_section]<\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>[vc_section el_class=&#8221;container mx-auto align-items-center text-right circle&#8211;pattern&#8221; css=&#8221;.vc_custom_1648956589196{padding-top: 3rem !important;}&#8221;][vc_row][vc_column][vc_wp_custommenu nav_menu=&#8221;3&#8243;][\/vc_column][\/vc_row][\/vc_section][vc_section css=&#8221;.vc_custom_1650785168913{background-color: #f6faff !important;}&#8221; el_class=&#8221;p-md-0&#8243;][vc_row el_class=&#8221;container mx-auto p-md-0&#8243;][vc_column width=&#8221;1\/4&#8243;][\/vc_column][vc_column width=&#8221;3\/4&#8243;][\/vc_column][\/vc_row][\/vc_section][vc_section css=&#8221;.vc_custom_1649210787516{background-color: #f6faff !important;}&#8221; el_class=&#8221;p-md-0 pt-md-5 pb-md-5&#8243;][vc_row el_class=&#8221;container mx-auto align-items-center text-right&#8221;][vc_column][\/vc_column][\/vc_row][\/vc_section]<\/p>\n","protected":false},"author":34,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"footnotes":""},"class_list":["post-26","page","type-page","status-publish","hentry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.6 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Proyectos - Instituto de Ciencias Agroalimentarias, Animales y Ambientales<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.uoh.cl\/instituto-de-ciencias-agroalimentarias\/proyectos\/\" \/>\n<meta property=\"og:locale\" content=\"es_ES\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Proyectos - Instituto de Ciencias Agroalimentarias, Animales y Ambientales\" \/>\n<meta property=\"og:description\" content=\"[vc_section el_class=&#8221;container mx-auto align-items-center text-right circle&#8211;pattern&#8221; 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